Annotation Detail for GABPB1
Basic Information Top
| Gene Symbol: | GABPB1 ( BABPB2,E4TF1,E4TF1-47,E4TF1-53,E4TF1B,GABPB,GABPB2,NRF2B1,NRF2B2 ) |
|---|---|
| Gene Full Name: | GA binding protein transcription factor, beta subunit 1 |
| Band: | 15q21.2 |
| Quick Links | Entrez ID:2553; OMIM: 600610; Uniprot ID:GABP1_HUMAN; ENSEMBL ID: ENSG00000104064; HGNC ID: 4074 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C404910 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GABPB1 mRNA] | affects expression|affects reaction | 19414516 |
| C404910 | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [FSHB protein affects the expression of GABPB1 mRNA] | affects expression|affects reaction | 19414516 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of GABPB1 mRNA | affects expression | 17562736 |
| D000242 | Cyclic AMP | 2,2-bis(4-hydroxyphenyl)-1,1,1-trichloroethane affects the reaction [Cyclic AMP affects the expression of GABPB1 mRNA] | affects expression|affects reaction | 19414516 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of GABPB1 mRNA | increases expression | 17942748 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 4.66 | 17505938 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 1.88 | 14692618 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 4.02 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 2.89 | 15885639 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 3.17 | 16105132 11677210 16919318 17110522 17681005 15861022 17333356 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 18713872 16109766 11529661 2444490 11743745 17562736 11739529 16393943 12594235 19923254 12392966 16485898 10663392 19370779 19164858 17522070 15619225 19085960 10774834 10915739 19420014 18071297 19416960 12958197 16227642 19739265 14986274 12540782 11834606 11287661 16177239 11461765 16781746 14725611 11421492 15968718 12153990 12705907 14550746 16081117 17906064 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 3.69 | 12538720 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 3.24 | 15345470 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 4.37 | 16945680 16569931 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 3.92 | 12013081 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 2.73 | 17937319 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 12587719 19014921 16610002 12969438 11587558 19460945 16611625 19784758 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 16871587 17185352 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D020326 | Migraine without Aura | Cyclic AMP | 5.66 | 11304026 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 4.15 | 11578682 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 3.94 | 16919318 15861022 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 4.66 | 16709447 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 4.08 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 3.52 | 15669648 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 3.80 | 14692618 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 3.97 | 14671159 15869587 |
| No data |