AutismKB 2.0

Annotation Detail for GABRA1


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Basic Information Top
Gene Symbol:GABRA1 ( ECA4,EJM,EJM5 )
Gene Full Name: gamma-aminobutyric acid (GABA) A receptor, alpha 1
Band: 5q34
Quick LinksEntrez ID:2554; OMIM: 137160; Uniprot ID:GBRA1_HUMAN; ENSEMBL ID: ENSG00000022355; HGNC ID: 4075
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
bipolar disorder
mood disorder
CHEMDEPENDENCY
PSYCH
depressive disorder, major
alcohol abuse
alcohol dependence
alcohol withdrawal alcoholism
No data
Desease Name
Epilepsy, childhood absence, susceptibility to, 4
Epilepsy, juvenile myoclonic, susceptibility to, 5
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|affects reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C118559 1-bromopropane 1-bromopropane results in decreased expression of GABRA1 mRNAdecreases expression 19576243
C038844 1-octen-3-ol 1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
C038844 1-octen-3-ol 1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
C036531 2,6-xylenol 2,6-xylenol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
C034047 2-cresol 2-cresol results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]affects binding|increases activity 11399263
C015542 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol GABRA1 protein affects the susceptibility to 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-olaffects response to substance 12490572
C054511 4,5-dimethyl-3-hydroxy-2(5H)-furanone 4,5-dimethyl-3-hydroxy-2(5H)-furanone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
C534316 7-hydroxy-7-methyl-3-methylene-1-octene 7-hydroxy-7-methyl-3-methylene-1-octene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D000481 Allantoin Allantoin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
C040534 alpha-hexachlorocyclohexane alpha-hexachlorocyclohexane results in decreased expression of GABRA1 mRNAdecreases expression 17785943
C006477 alphaxalone alphaxalone promotes the reaction [Flunitrazepam binds to GABRA1 protein]affects binding|increases reaction 8397295
C006477 alphaxalone alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
C006477 alphaxalone alphaxalone results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D005680 gamma-Aminobutyric Acid 1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D005680 gamma-Aminobutyric Acid 1-octen-3-ol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D005680 gamma-Aminobutyric Acid 4,5-dimethyl-3-hydroxy-2(5H)-furanone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D005680 gamma-Aminobutyric Acid 7-hydroxy-7-methyl-3-methylene-1-octene promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D005680 gamma-Aminobutyric Acid Allantoin inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid benzothiazole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D005680 gamma-Aminobutyric Acid catechol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D005680 gamma-Aminobutyric Acid Chlorogenic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid Coffee inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid Ethanol analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 12926865
D005680 gamma-Aminobutyric Acid geraniol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D005680 gamma-Aminobutyric Acid Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D005680 gamma-Aminobutyric Acid linalool promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D005680 gamma-Aminobutyric Acid maltol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid Theobromine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid Theophylline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D005680 gamma-Aminobutyric Acid 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]affects binding|affects reaction|increases activity 11137757
D005680 gamma-Aminobutyric Acid beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction|increases activity 15588619
D005680 gamma-Aminobutyric Acid Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]affects binding|increases activity|increases reaction 11156579
D005680 gamma-Aminobutyric Acid Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|affects reaction 14637376
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 11812690
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]affects binding|increases activity 11137757
D005680 gamma-Aminobutyric Acid isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]affects binding|decreases reaction|increases activity 11156579
D005680 gamma-Aminobutyric Acid Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D005680 gamma-Aminobutyric Acid Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 11812690
D005680 gamma-Aminobutyric Acid Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D005680 gamma-Aminobutyric Acid Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]affects binding|increases activity 1712603
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D005680 gamma-Aminobutyric Acid alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 1977069
D005680 gamma-Aminobutyric Acid Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects activity|affects binding 17054655
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]affects binding|increases activity 1977069
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]affects cotreatment|increases activity 11123204
D005680 gamma-Aminobutyric Acid [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]affects binding|increases activity 2165521
D005680 gamma-Aminobutyric Acid methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D005680 gamma-Aminobutyric Acid pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D005680 gamma-Aminobutyric Acid Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GABRA1 mRNAaffects expression 16483693
C016986 apraclonidine apraclonidine binds to and affects the activity of GABRA1 proteinaffects activity|affects binding 17496723
C006632 arsenic trioxide arsenic trioxide results in increased expression of GABRA1 mRNAincreases expression 20458559
C005465 benzothiazole benzothiazole promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
C005790 beta-thujone beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction|increases activity 15588619
D001640 Bicuculline Bicuculline inhibits the reaction [Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|decreases reaction|increases activity 16569037
D001640 Bicuculline Bicuculline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 1977069
D001640 Bicuculline Bicuculline results in decreased expression of GABRA1 mRNAdecreases expression 9600394
C054626 bretazenil bretazenil binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C015044 bromoform bromoform binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects activity|affects binding 12505655
D020001 1-Butanol 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]affects binding|affects reaction|increases activity 11137757
D020001 1-Butanol 1-Butanol results in increased activity of GABRA1 proteinincreases activity 16807363
D002164 Camphor Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C006923 carvone carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C034221 catechol catechol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D002712 Chlorides GABRA1 protein affects the reaction [Muscimol results in increased uptake of Chlorides]affects reaction|increases uptake 12490572
D002712 Chlorides [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D002712 Chlorides topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D002726 Chlorogenic Acid Chlorogenic Acid inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
C021604 CL 218872 CL 218872 binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D003000 Clonidine Clonidine binds to and affects the activity of GABRA1 proteinaffects activity|affects binding 17496723
D003024 Clozapine Clozapine results in increased expression of GABRA1 mRNAincreases expression 17266109
D003069 Coffee Coffee inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D003474 Curcumin Curcumin results in decreased expression of GABRA1 mRNAdecreases expression 18299980
C086916 delta-hexachlorocyclohexane delta-hexachlorocyclohexane promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]affects binding|increases activity|increases reaction 11156579
C086916 delta-hexachlorocyclohexane delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]affects binding|decreases activity 11156579
C086916 delta-hexachlorocyclohexane delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]affects binding|decreases activity 11156579
D003975 Diazepam Diazepam affects the activity of GABRA1 proteinaffects activity 15864560
D003975 Diazepam Diazepam promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D003975 Diazepam Diazepam results in decreased expression of GABRA1 mRNAdecreases expression 15802192
D003975 Diazepam Diazepam results in increased activity of GABRA1 proteinincreases activity 15613639
D004026 Dieldrin Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D004026 Dieldrin Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D004026 Dieldrin Dieldrin results in decreased expression of GABRA1 mRNAdecreases expression 9600394
D007980 Levodopa Levodopa results in decreased expression of GABRA1 mRNAdecreases expression 15837143
D007980 Levodopa Levodopa results in decreased expression of GABRA1 proteindecreases expression 15837143
D000431 Ethanol Bicuculline inhibits the reaction [Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|decreases reaction|increases activity 16569037
D000431 Ethanol Ethanol analog promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 12926865
D000431 Ethanol Ethanol analog results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]affects cotreatment|increases activity 16569037
D000431 Ethanol Ethanol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D000431 Ethanol Ethanol results in increased activity of GABRA1 proteinincreases activity 16807363
D000431 Ethanol GABRA1 protein affects the susceptibility to Ethanolaffects response to substance 12490572
D000431 Ethanol Ethanol results in decreased expression of GABRA1 mRNAdecreases expression 2158791
1711815
D005045 Etomidate Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D005045 Etomidate Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D005045 Etomidate Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005045 Etomidate Etomidate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D005442 Flumazenil Flumazenil promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D005445 Flunitrazepam Flunitrazepam binds to GABRA1 proteinaffects binding 17496723
D005445 Flunitrazepam Flunitrazepam binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D005445 Flunitrazepam alphaxalone promotes the reaction [Flunitrazepam binds to GABRA1 protein]affects binding|increases reaction 8397295
D005445 Flunitrazepam Flunitrazepam binds to GABRA1 proteinaffects binding 8397295
D005445 Flunitrazepam Pentobarbital promotes the reaction [Flunitrazepam binds to GABRA1 protein]affects binding|increases reaction 8397295
D005479 Flurazepam Flurazepam binds to and affects the activity of GABRA1 proteinaffects activity|affects binding 17496723
D005479 Flurazepam GABRA1 protein affects the susceptibility to Flurazepamaffects response to substance 12490572
D005481 Flurothyl Flurothyl results in decreased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]affects binding|decreases activity 11090101
D005576 Forskolin Forskolin results in increased expression of GABRA1increases expression 9147380
D018682 GABA Agents GABA Agents binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C007836 geraniol geraniol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D006139 Guaiacol Guaiacol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 14664509
D006220 Haloperidol Haloperidol results in decreased expression of GABRA1 mRNAdecreases expression 18797397
C022871 isoborneol isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D007530 Isoflurane Isoflurane results in increased activity of GABRA1 proteinincreases activity 16807363
C063822 L 663581 L 663581 binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C018584 linalool linalool promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB1 protein]]affects cotreatment|increases activity|increases reaction 16569037
D001556 Lindane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D001556 Lindane Lindane inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein alternative form]]affects binding|decreases reaction|increases activity 11156579
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of GABRA1 mRNAincreases expression 12057914
D008140 Lorazepam Lorazepam results in decreased expression of GABRA1 mRNAdecreases expression 16107249
C008316 maltol maltol inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D008610 Menthol Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C019466 menthone menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C034818 methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate methyl 6,7-dimethoxy-4-ethyl-beta-carboline-3-carboxylate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D009020 Morphine Morphine results in decreased expression of GABRA1 mRNAdecreases expression 15183518
D009020 Morphine Morphine results in increased expression of GABRA1 mRNAincreases expression 15183518
D009118 Muscimol GABRA1 protein affects the reaction [Muscimol results in increased uptake of Chlorides]affects reaction|increases uptake 12490572
D010424 Pentobarbital Pentobarbital binds to and affects the activity of GABRA1 proteinaffects activity|affects binding 17496723
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D010424 Pentobarbital Pentobarbital results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]affects binding|increases activity 10049148
D010424 Pentobarbital Pentobarbital results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]affects binding|increases activity 10049148
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 1712603
D010424 Pentobarbital Pentobarbital affects the expression of GABRA1 mRNAaffects expression 8787126
D010424 Pentobarbital Pentobarbital promotes the reaction [Flunitrazepam binds to GABRA1 protein]affects binding|increases reaction 8397295
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|increases activity|increases reaction 1977069
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D010424 Pentobarbital Pentobarbital results in decreased expression of GABRA1 mRNAdecreases expression 8207435
D010424 Pentobarbital Pentobarbital results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D010424 Pentobarbital Pentobarbital results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB1 protein]affects binding|increases activity 2165521
D010433 Pentylenetetrazole Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010433 Pentylenetetrazole Pentylenetetrazole inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010622 Phencyclidine Phencyclidine results in increased expression of GABRA1 mRNAincreases expression 17266109
C033457 phenobarbital quinidine phenobarbital quinidine results in decreased expression of GABRA1 mRNAdecreases expression 15802192
D010852 Picrotoxin Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D010852 Picrotoxin Picrotoxin results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
C018370 pregnenolone sulfate pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
C018370 pregnenolone sulfate pregnenolone sulfate results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
D015742 Propofol Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRE]]affects binding|increases activity|increases reaction 10049148
D015742 Propofol Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 binds to GABRB1 binds to GABRG2]]affects binding|increases activity|increases reaction 10049148
D015742 Propofol Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D015742 Propofol Propofol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D015742 Propofol Propofol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
C046308 tert-butylbicyclo-2-benzoate tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Pentylenetetrazole inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding 14637376
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D043343 Testosterone Propionate Testosterone Propionate results in decreased expression of GABRA1 mRNAdecreases expression 16957604
D013805 Theobromine Theobromine inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D013806 Theophylline Theophylline inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB1 protein]]affects binding|decreases reaction|increases activity 14664509
D013943 Thymol Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
D014050 Toluene Toluene affects the expression of GABRA1 mRNAaffects expression 17108153
C052342 topiramate topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D014520 Urethane Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 11812690
D015016 Yohimbine Yohimbine binds to and affects the activity of GABRA1 proteinaffects activity|affects binding 17496723
D015032 Zinc Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D015032 Zinc Zinc results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
C049109 zolpidem zolpidem binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C049109 zolpidem GABRA1 protein affects the susceptibility to zolpidemaffects response to substance 12490572
C049109 zolpidem GABRA1 protein results in increased susceptibility to zolpidemincreases response to substance 16630580
C049109 zolpidem zolpidem results in increased activity of GABRA1 proteinincreases activity 16162846
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 3.2017676605 18926900
MESH:D000138 Acidosis Ammonium Chloride 8.0018287403
MESH:D000138 Acidosis Ethanol 8.0011192467
MESH:D000169 Acrodermatitis Zinc 4.6616889938 17190629 17202136
MESH:D055371 Acute Lung Injury Lipopolysaccharides 3.3511850527 18653653
MESH:D000230 Adenocarcinoma arsenic trioxide 3.9919825857 11798837
MESH:D000230 Adenocarcinoma Urethane 3.9918316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 4.9515814487
MESH:D000236 Adenoma Urethane 3.5210530776 10822126 17093202 16926031 11497255 6695378 17195641
MESH:D000380 Agranulocytosis Clozapine 4.3312649775 14617031 16160616
MESH:D000382 Agricultural Workers' Diseases Lindane 3.6512661182
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.5615451040 15451039
MESH:D000437 Alcoholism topiramate 4.4317925516 19331489 18552399
MESH:D019973 Alcohol-Related Disorders Curcumin 4.3217887948
MESH:D000544 Alzheimer Disease Curcumin 3.7315590663
MESH:D000544 Alzheimer Disease Zinc 3.7316580781 17119284 16410023 16325427
MESH:D000755 Anemia, Sickle Cell Zinc 4.1916916123
MESH:D000853 Anophthalmos Ethanol 4.0915513904
MESH:D001008 Anxiety Disorders Diazepam 11.6918313124 16284244
MESH:D001008 Anxiety Disorders Ethanol 11.6911141031
MESH:D001008 Anxiety Disorders Pentobarbital 11.6918313124 11141031
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.5216807698
MESH:D001249 Asthma Theophylline 4.639701106 12113382
MESH:D001249 Asthma Zinc 4.6317085522
MESH:D001259 Ataxia 1-Butanol 4.897820390
MESH:D050197 Atherosclerosis Curcumin 2.8418704882
MESH:D001321 Autistic Disorder marker/mechanism 18821008
MESH:D001321 Autistic Disorder Haloperidol 2.8719368416 18080171
MESH:D001327 Autoimmune Diseases Curcumin 3.7719761891
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 3.0016206674
MESH:D001836 Body Weight Changes 2-cresol 5.9612820538
MESH:D001930 Brain Injuries Zinc 3.9617109824
MESH:D002545 Brain Ischemia Curcumin 8.1816770732
MESH:D002545 Brain Ischemia Morphine 8.1819211983
MESH:D001932 Brain Neoplasms Curcumin 3.2917596214
MESH:D001943 Breast Neoplasms Curcumin 2.3318462866 19250217 16243823 18593918
MESH:D001943 Breast Neoplasms Dieldrin 2.3315770527 11859874
MESH:D001943 Breast Neoplasms Lindane 2.3314688026
MESH:D002051 Burkitt Lymphoma arsenic trioxide 3.6311589617
MESH:D002056 Burns Ethanol 3.9216374292
MESH:D002277 Carcinoma Curcumin 3.2318593918
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 2.7714691202 11135700 16217749 15553829 15073043
MESH:D006528 Carcinoma, Hepatocellular Ethanol 2.7715289165 15763234 18788625
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 2.6618414057
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.1119014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.4612490120
MESH:D002294 Carcinoma, Squamous Cell Curcumin 4.1018462866
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.1016543248
MESH:D006332 Cardiomegaly Ethanol 2.9819332462
MESH:D002318 Cardiovascular Diseases Zinc 3.1216936243
MESH:D002375 Catalepsy Haloperidol 4.1715215559 1977408
MESH:D002471 Cell Transformation, Neoplastic bromoform 4.8518075178
MESH:D002547 Cerebral Palsy Toluene 5.109294310
MESH:D002637 Chest Pain Theophylline 5.1115238202
MESH:D002659 Child Development Disorders, Pervasive topiramate 3.7715650499
MESH:D002971 Cleft Lip Ethanol 3.1415513904
MESH:D002972 Cleft Palate Diazepam 8.063629520
MESH:D002972 Cleft Palate Ethanol 8.0615513904
MESH:D002972 Cleft Palate Urethane 8.0612810352
MESH:D003072 Cognition Disorders Clozapine 4.2417123785
MESH:D003092 Colitis Curcumin 3.4616804969 18200517 16782535
MESH:D003103 Coloboma Curcumin 3.8718809619
MESH:D003110 Colonic Neoplasms Curcumin 4.1819359593 16340194
MESH:D003110 Colonic Neoplasms geraniol 4.1815374632
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D016510 Corneal Neovascularization Curcumin 4.1718497527
MESH:D023903 Coronary Restenosis arsenic trioxide 3.4712609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 4.4810525206
MESH:D019465 Craniofacial Abnormalities Ethanol 4.4810194807 11198716 15451040 15451039 15513904 19302082 11873399
MESH:D019465 Craniofacial Abnormalities Toluene 4.489294310
MESH:D019465 Craniofacial Abnormalities Zinc 4.4819302082
MESH:D003643 Death Pentylenetetrazole 11.376431079
MESH:D003643 Death Toluene 11.376431079
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 8.6215213294
MESH:D016757 Death, Sudden, Cardiac Haloperidol 8.6220210726
MESH:D003704 Dementia Haloperidol 3.9111575062
MESH:D003920 Diabetes Mellitus Zinc 3.5716479319
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 6.0016402076
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 6.0018403477
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 6.0016979414
MESH:D003928 Diabetic Nephropathies Curcumin 3.3718204486
MESH:D003967 Diarrhea Morphine 3.842540324
MESH:D006970 Disorders of Excessive Somnolence Clozapine 4.7915331141
MESH:D056486 Drug-Induced Liver Injury Ethanol 2.3911566570
MESH:D004381 Duodenal Ulcer Curcumin 3.3517351913
MESH:D004409 Dyskinesia, Drug-Induced Levodopa 5.613690436 15893579
MESH:D050171 Dyslipidemias Clozapine 3.6216402076
MESH:D004421 Dystonia Diazepam 4.981851702
MESH:D019446 Endotoxemia Lipopolysaccharides 3.6617637181 15821434 15328337
MESH:D004751 Enteritis Clonidine 5.378982514
MESH:D004828 Epilepsies, Partial Diazepam 4.793922381
MESH:D004827 Epilepsy Diazepam 6.31821787
MESH:D004827 Epilepsy topiramate 6.3119148780
MESH:D004832 Epilepsy, Absence Diazepam 8.106426943 6401628
MESH:D004832 Epilepsy, Absence Pentylenetetrazole 8.106426943
OMIM:611136 EPILEPSY, JUVENILE MYOCLONIC, SUSCEPTIBILITY TO, 5 marker/mechanism
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.5116499746
MESH:D004938 Esophageal Neoplasms arsenic trioxide 5.8512903497
MESH:D004938 Esophageal Neoplasms Ethanol 5.8516704527
MESH:D004938 Esophageal Neoplasms Zinc 5.8516543248
MESH:D005234 Fatty Liver arsenic trioxide 9.4515073043
MESH:D005234 Fatty Liver Curcumin 9.4519297423
MESH:D005234 Fatty Liver Ethanol 9.4519236843 18620774 16409862
MESH:D005235 Fatty Liver, Alcoholic Ethanol 4.9017920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.5516946407 15513904 15451040 10194807
MESH:D005334 Fever Lipopolysaccharides 3.369205823 11852909
MESH:D005355 Fibrosis Curcumin 3.2718705752
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 3.5516904648
MESH:D005756 Gastritis Ethanol 9.0215046732
MESH:D005756 Gastritis Zinc 9.0217241300
MESH:D005770 Gastrointestinal Neoplasms Curcumin 3.9718462866
MESH:D005902 Glaucoma, Open-Angle apraclonidine 6.4610457699
MESH:D005909 Glioblastoma Curcumin 2.9617596214
MESH:D006130 Growth Disorders Zinc 3.4417217573
MESH:D006258 Head and Neck Neoplasms Curcumin 3.1218462866 18829502
MESH:D006331 Heart Diseases Urethane 3.6916046796
MESH:D006333 Heart Failure Zinc 3.1117162251
MESH:D006335 Heart Injuries Zinc 5.0117074742
MESH:D016481 Helicobacter Infections Zinc 3.8417241300
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.7216366002
MESH:D006501 Hepatic Encephalopathy marker/mechanism 15929193
MESH:D006527 Hepatolenticular Degeneration Zinc 3.9617276780
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 4.3117701891
MESH:D006930 Hyperalgesia Ethanol 6.9618783367
MESH:D006930 Hyperalgesia Yohimbine 6.9612727271
MESH:D006937 Hypercholesterolemia Curcumin 3.3818704882
MESH:D020138 Hyperhomocysteinemia Levodopa 5.0616275827 16787708
MESH:D006948 Hyperkinesis Clozapine 4.1716046005
MESH:D046110 Hypertension, Pregnancy-Induced Clonidine 5.4316612254
MESH:D007022 Hypotension Isoflurane 4.2612967683
MESH:D007247 Infertility, Female Dieldrin 4.2510630421
MESH:D007248 Infertility, Male Theophylline 3.9016988215
MESH:D007249 Inflammation Curcumin 4.0317151092 18403477 16956363
MESH:D007249 Inflammation Lipopolysaccharides 4.039205823 17237260 12878042 17255318 17963957
MESH:D015212 Inflammatory Bowel Diseases Curcumin 2.8518200517 18596194
MESH:D007414 Intestinal Neoplasms Curcumin 3.5610783313
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 3.9317255318
MESH:D007511 Ischemia Zinc 3.9016584753
MESH:D007569 Jaw Abnormalities Ethanol 3.7315513904
MESH:D007674 Kidney Diseases Zinc 2.8716960431
MESH:D007676 Kidney Failure, Chronic Zinc 3.7516518626
MESH:D007859 Learning Disorders Ethanol 3.4915451040
MESH:D007889 Leiomyoma Curcumin 3.8818555241
MESH:D007938 Leukemia arsenic trioxide 5.0715070760
MESH:D007938 Leukemia Curcumin 5.0718462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 7.5217077332 12560223
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 7.5216106398
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 3.5616972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 2.8514633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 3.0919077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 1.9820471514 19850784 16467208 16968895 17050201
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 2.6916112521 19225113 17712046 11161223 19642359 15336539 19035177 12679006 16823087 15622746 12712474 17217047 17649720 16331271 17107899 16966277 11468182 17869043 9834237 12018890 19075265 16330433 15213294 15748426 16891316
MESH:D015458 Leukemia, T-Cell arsenic trioxide 9.3516882451
MESH:D015458 Leukemia, T-Cell Curcumin 9.3516106398
MESH:D007970 Leukopenia Lipopolysaccharides 3.9515821434
MESH:D017880 Limb Deformities, Congenital Ethanol 3.2517676605
MESH:D008064 Lipidoses Clozapine 3.4017567588
MESH:D008103 Liver Cirrhosis Ethanol 2.9215289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.3518295389
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 3.0217355460 18006644 18705752
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 3.0218166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 3.0212878042
MESH:D008107 Liver Diseases Curcumin 3.7916956363
MESH:D008107 Liver Diseases Lindane 3.791715830
MESH:D008108 Liver Diseases, Alcoholic Ethanol 3.9217347304 17207112
MESH:D008113 Liver Neoplasms arsenic trioxide 5.7414682389
MESH:D008113 Liver Neoplasms Dieldrin 5.749539021 8742319
MESH:D008113 Liver Neoplasms Urethane 5.7417559639 17093202 16391232
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 2.2620377131
MESH:D008133 Long QT Syndrome arsenic trioxide 2.7615213294
MESH:D055370 Lung Injury Lipopolysaccharides 3.2921114838
MESH:D008175 Lung Neoplasms arsenic trioxide 2.9919825857 11798837
MESH:D008175 Lung Neoplasms Curcumin 2.9918462866 19359593 16243823
MESH:D008175 Lung Neoplasms Urethane 2.9911807781 7750092 16926031 16337739 10822126 16788158 17195641 11246140 17255336 10530776 11323394 14587096 12765245 10779650 12117781 11307925 17093202 11552296 16204055 11062179 10997738 11074608 15902970 15136453 11544531 11497255 12466968 6695378 16007126 16289808 11992545 16391232 12957351 11893704 15166089
MESH:D008223 Lymphoma Curcumin 3.0318462866
MESH:D016399 Lymphoma, T-Cell Curcumin 3.9716173963
MESH:D008325 Mammary Neoplasms, Experimental Zinc 2.8112773700
MESH:D008545 Melanoma Curcumin 2.3017885582 18462866
MESH:D008569 Memory Disorders Curcumin 7.4017263510
MESH:D008569 Memory Disorders Ethanol 7.4018411066 15451040
MESH:D001523 Mental Disorders Clozapine 5.9516856516
MESH:D001523 Mental Disorders Haloperidol 5.9516856516
MESH:D008607 Mental Retardation Toluene 3.349294310
MESH:D024821 Metabolic Syndrome X Clozapine 3.7819142101
MESH:D008881 Migraine Disorders topiramate 4.0218803445 16942474 18765137 18759728
MESH:D019957 Motor Skills Disorders Toluene 4.549294310
MESH:D009101 Multiple Myeloma arsenic trioxide 5.5714977855 11468182 19417148 19549372 15949261
MESH:D009101 Multiple Myeloma Curcumin 5.5719372569
MESH:D009134 Muscular Atrophy, Spinal Curcumin 4.1717962980
MESH:D009182 Mycosis Fungoides arsenic trioxide 3.9118349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 2.6716105982 16882451
MESH:D020190 Myoclonic Epilepsy, Juvenile marker/mechanism
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 7.9716624393
MESH:D009361 Neoplasm Invasiveness Curcumin 7.9718495463
MESH:D009369 Neoplasms Dieldrin 6.238820588
MESH:D009369 Neoplasms Lindane 6.2312807735 16818664
MESH:D009369 Neoplasms Urethane 6.2315625555
MESH:D009374 Neoplasms, Experimental Urethane 3.9615582191
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 3.7812497104
MESH:D009423 Nervous System Neoplasms Curcumin 4.8718462866
MESH:D009436 Neural Tube Defects arsenic trioxide 2.6010525206
MESH:D009765 Obesity Clozapine 4.1919142110 18515891
MESH:D009765 Obesity Curcumin 4.1919297423
MESH:D010024 Osteoporosis Curcumin 2.9718719352
MESH:D010051 Ovarian Neoplasms arsenic trioxide 6.2919769630 16624393 12452020
MESH:D010051 Ovarian Neoplasms Curcumin 6.2919020741 18462866
MESH:D010051 Ovarian Neoplasms Urethane 6.2916391232
MESH:D010146 Pain Morphine 3.6020225289 16273134 15275824 6776300 18699797 15215642
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 6.7515580305
MESH:D010190 Pancreatic Neoplasms Curcumin 6.7517440100 19401701 19196508
MESH:D010190 Pancreatic Neoplasms Ethanol 6.7512384795
MESH:D010235 Paraganglioma arsenic trioxide 3.4719927285
MESH:D010300 Parkinson Disease Dieldrin 5.2717291500 16112328 11181820 11445065 16809432
MESH:D010300 Parkinson Disease Levodopa 5.2711432539 19594199 20334432 7566641 18328768
MESH:D020734 Parkinsonian Disorders Levodopa 5.018817341 11246459 18722529
MESH:D010538 Peritonitis Isoflurane 4.5017414419
MESH:D010911 Pituitary Neoplasms Urethane 4.6816391232
MESH:D011014 Pneumonia Lipopolysaccharides 3.8111605937 12224865
MESH:D011225 Pre-Eclampsia Zinc 3.5817114810
MESH:D011471 Prostatic Neoplasms arsenic trioxide 2.4419131511
MESH:D011471 Prostatic Neoplasms Curcumin 2.4415129424 11398177 18156803 10851300 12497104 18769126 18226269
MESH:D011471 Prostatic Neoplasms Lindane 2.4414688026 12661182
MESH:D011471 Prostatic Neoplasms Zinc 2.4416517595 16700911 12429649 16606632
MESH:D011595 Psychomotor Agitation Haloperidol 4.2311575062
MESH:D011618 Psychotic Disorders Clozapine 7.2615331141
MESH:D011618 Psychotic Disorders Haloperidol 7.2611575062
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.5418983928
MESH:D011656 Pulmonary Emphysema Curcumin 3.8619168576
MESH:D012004 Rectal Neoplasms bromoform 5.6517535441
MESH:D012021 Reflex, Abnormal Pentobarbital 5.2710930210
MESH:D015427 Reperfusion Injury Morphine 3.7119211983
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 3.3418379247 10666014
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.2010835634
MESH:D012162 Retinal Degeneration Zinc 3.5416584753
MESH:D012509 Sarcoma Curcumin 3.4618462866
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 3.2516646077
MESH:D012559 Schizophrenia Clozapine 3.5520521326 18806925 20452607 20521320 17726453 16141801 11763009 17667964 18855531 19369910 20107430 11151749 20580759 17123785 20168265
MESH:D012559 Schizophrenia Haloperidol 3.5520107430 19369910 1830565 18513383
MESH:C537537 Segawa syndrome, autosomal recessive Levodopa 5.948817341
MESH:D012640 Seizures Clonidine 39.9910087439
MESH:D012640 Seizures Diazepam 39.9910087439 15946322 9754883
MESH:D012640 Seizures Ethanol 39.999754883
MESH:D012640 Seizures Flurothyl 39.993352866
MESH:D012640 Seizures Lindane 39.9915475178 7539098 12842176
MESH:D012640 Seizures Lorazepam 39.9910087439 16107249
MESH:D012640 Seizures Pentobarbital 39.999754883 10087439
MESH:D012640 Seizures Pentylenetetrazole 39.993037702 6431079 8954991 18164287 18657176 2616065 15475178 19660546 16054440 3352866
MESH:D012640 Seizures Picrotoxin 39.998635557 8954991
MESH:D012640 Seizures Toluene 39.999294310 6431079
MESH:D012640 Seizures topiramate 39.9916499746
MESH:D012640 Seizures zolpidem 39.999754883
MESH:D018805 Sepsis Curcumin 7.7318389075
MESH:D018805 Sepsis Isoflurane 7.7317414419
MESH:D012878 Skin Neoplasms Urethane 3.3211807781
MESH:D012893 Sleep Disorders zolpidem 5.6119395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Clonidine 17.7218280681
MESH:D007319 Sleep Initiation and Maintenance Disorders Flurazepam 17.7215341891
MESH:D007319 Sleep Initiation and Maintenance Disorders Lorazepam 17.7215341891
MESH:D007319 Sleep Initiation and Maintenance Disorders zolpidem 17.7215341891 17225163 9066939
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.3917007042
MESH:D013274 Stomach Neoplasms Ethanol 2.3918456281
MESH:D013276 Stomach Ulcer Curcumin 5.3719188055 16631530
MESH:D013276 Stomach Ulcer Ethanol 5.379211565 11906479 9562338 16755016 17189318 17918041
MESH:D013375 Substance Withdrawal Syndrome Diazepam 18.149754883
MESH:D013375 Substance Withdrawal Syndrome Ethanol 18.149754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 18.1411529278 9754883
MESH:D013375 Substance Withdrawal Syndrome zolpidem 18.149754883
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.0020210726
MESH:D013733 Testicular Diseases Toluene 4.2210048760 10514026
MESH:D013742 Tetanus Propofol 5.672903605
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.5115821434
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.5219014326
MESH:D014062 Tongue Neoplasms Zinc 3.7416543248
MESH:D016171 Torsades de Pointes arsenic trioxide 3.2215213294
MESH:D014202 Tremor 2-cresol 5.6212820538
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 4.1120435036 11780464 12973940 12845720
MESH:D001749 Urinary Bladder Neoplasms Curcumin 4.1118593936
MESH:D014565 Urogenital Neoplasms Curcumin 4.5218462866
MESH:D019043 Vascular Neoplasms Urethane 5.1510620525
MESH:D015430 Weight Gain Clozapine 3.8317502770 20564506 20107430 16402076 20521320 16141801
MESH:D015431 Weight Loss Clozapine 4.3317933447
Pathway ID Pathway Name
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:13685 Synaptic Transmission
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28489
    • No data
    No data
    Releated drug ID Related drug Name
    PA449283diazepam
    PA164781320flunitrazepam
    PA164743987etomidate
    PA164783813adinazolam
    PA448333alprazolam
    PA10402benzodiazepine derivatives
    PA10035bromazepam
    PA448932chlordiazepoxide
    PA164748034cinolazepam
    PA10888clobazam
    PA449050clonazepam
    PA164749297clorazepate
    PA449502estazolam
    PA449681flurazepam
    PA164746526halazepam
    PA164749385ketazolam
    PA450267lorazepam
    PA450496midazolam
    PA10242nitrazepam
    PA450731oxazepam
    PA164776668prazepam
    PA164744373quazepam
    PA451608temazepam
    PA451753triazolam
    PA449659flumazenil
    PA164743471adenosine triphosphate
    PA449659flumazenil
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00186 potentiator Lorazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Benzodiazepines;GABA Modulators
    DB00189 agonist Ethchlorvynol Hypnotics and Sedatives
    DB00228 agonist Enflurane Anesthetics, Inhalation;General Anesthetics
    DB00231 potentiator Temazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00237 potentiator Butabarbital Anti-anxiety Agents;Hypnotics and Sedatives;Barbiturates
    DB00241 potentiator Trianal-C 1/2 Capsule Analgesics
    DB00273 agonist Topiramate Anticonvulsants;Anti-Obesity Agents;Neuroprotective Agents
    DB00292 agonist Etomidate Hypnotics and Sedatives;Anesthetics, Intravenous
    DB00306 potentiator Talbutal Analgesics
    DB00312 potentiator Cafergot PB Tab Hypnotics and Sedatives;Adjuvants, Anesthesia;GABA Modulators;Barbiturates
    DB00349 potentiator Clobazam Anticonvulsants;Benzodiazepines
    DB00371 agonist Equagesic Tablets Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;Muscle Relaxants, Central
    DB00402 agonist Eszopiclone Hypnotics and Sedatives
    DB00404 potentiator Alprazolam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB00418 potentiator Secobarbital Hypnotics and Sedatives;Adjuvants, Anesthesia;GABA Modulators;Barbiturates;Adjuvants
    DB00425 agonist Zolpidem GABA Agonists;Hypnotics and Sedatives
    DB00463 potentiator Metharbital Anticonvulsants
    DB00466 antagonist Picrotoxin Central Nervous System Stimulants;Stimulants;Anti-barbituates;GABA receptor antagonists;Antidotes;Convulsants;GABA Antagonists
    DB00474 antagonist Methohexital Barbiturates;Anesthetics;Anesthetics, Intravenous
    DB00475 potentiator Pro Chlorax Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00543 antagonist Amoxapine Adrenergic Uptake Inhibitors;Dopamine Antagonists;Serotonin Uptake Inhibitors;Antidepressive Agents, Second-Generation;Neurotransmitter Uptake Inhibitors
    DB00546 potentiator Adinazolam Anti-anxiety Agents;Antidepressive Agents
    DB00599 potentiator Thiotal 5g Hypnotics and Sedatives;Anticonvulsants;GABA Modulators;Anesthetics, Intravenous
    DB00628 potentiator Clorazepate Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB00683 potentiator Midazolam Anti-anxiety Agents;Hypnotics and Sedatives;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous
    DB00690 potentiator Flurazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00753 agonist Isoflurane Anesthetics, Inhalation;General Anesthetics;Anesthetics
    DB00794 potentiator Primidone Anticonvulsants;Barbiturates
    DB00801 potentiator Halazepam Anti-anxiety Agents;Muscle Relaxants;Benzodiazepines;Sedative
    DB00829 potentiator Diazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous;Muscle Relaxants, Central
    DB00837 agonist Progabide Antidepressants;GABA Agonists;Anticonvulsants;Antiparkinson Agents;Antidyskinetics;Antidepressive Agents
    DB00842 potentiator Oxazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00849 potentiator Methylphenobarbital Hypnotics and Sedatives;Anticonvulsants;GABA Modulators
    DB00897 potentiator Triazolam Anti-anxiety Agents;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00898 agonist Ethanol Anti-Infective Agents, Local;Solvents;Central Nervous System Depressants;Disinfectants
    DB00962 potentiator Zaleplon Hypnotics and Sedatives;Anticonvulsants;Anxiolytics sedatives and hypnotics
    DB01028 agonist Methoxyflurane Anesthetics, Inhalation
    DB01068 potentiator Clonazepam Anticonvulsants;Benzodiazepines;GABA Modulators
    DB01107 agonist Methyprylon Sedatives and Hypnotics
    DB01154 agonist Thiamylal Hypnotics and Sedatives;GABA Modulators;Anesthetics, Intravenous
    DB01159 other/unknown Halothane Anesthetics, Inhalation;General Anesthetics;Anesthetics
    DB01174 potentiator Phenobarbital Hypnotics and Sedatives;Anticonvulsants;GABA Modulators;Excitatory Amino Acid Antagonists
    DB01189 agonist Desflurane Anesthetics, Inhalation;Neuroprotective Agents
    DB01198 agonist Zopiclone Hypnotics and Sedatives
    DB01205 antagonist Flumazenil GABA Modulators;Antidotes
    DB01215 potentiator Estazolam Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB01236 agonist Sevoflurane Platelet Aggregation Inhibitors;Anesthetics, Inhalation
    DB01287 agonist Dihydroergotoxine
    DB01341 potentiator Dihydroquinidine barbiturate
    DB01346 agonist Quinidine barbiturate
    DB01351 potentiator Amobarbital Hypnotics and Sedatives;GABA Modulators
    DB01352 potentiator Aprobarbital
    DB01353 potentiator Butethal Anti-anxiety Agents;Hypnotics and Sedatives;Barbiturates
    DB01354 potentiator Heptabarbital Hypnotics and Sedatives;Barbiturates
    DB01355 potentiator Hexobarbital Hypnotics and Sedatives;GABA Modulators;Barbiturates;Adjuvants
    DB01381 negative modulator Ginkgo biloba
    DB01437 agonist Glutethimide Hypnotics and Sedatives
    DB01483 potentiator Barbital Hypnotics and Sedatives;GABA Modulators
    DB01496 potentiator Barbituric acid derivative
    DB01558 potentiator Bromazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB01559 potentiator Clotiazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;Benzodiazepines
    DB01567 potentiator Fludiazepam Anti-anxiety Agents;Benzodiazepines
    DB01587 potentiator Ketazolam Anti-anxiety Agents;Benzodiazepines
    DB01588 potentiator Prazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB01589 potentiator Quazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB01594 agonist Cinolazepam Anticonvulsants;Benzodiazepines;Sedatives and Hypnotics
    DB01595 potentiator Nitrazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;GABA Modulators
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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