Annotation Detail for PAN3
Basic Information
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| Gene Symbol: | PAN3 ( - ) |
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| Gene Full Name: | PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae) |
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| Band: | 13q12.2 |
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| Quick Links | Entrez ID:255967; OMIM: NA; Uniprot ID:PAN3_HUMAN; ENSEMBL ID: ENSG00000152520; HGNC ID: 29991 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
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| Metabolism of RNA |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of PAN3 mRNA | decreases expression | 19150397
|
| C051890 |
irinotecan |
irinotecan analog results in decreased expression of PAN3 mRNA | decreases expression | 18927307
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
3.04 | 20889678 |
| MESH:D003110 |
Colonic Neoplasms |
|
irinotecan |
2.65 | 17725105 17287894 |
| MESH:D015179 |
Colorectal Neoplasms |
|
irinotecan |
2.37 | 18509181 16391804 17454858 17159606 16303861 18259882 15273666 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.16 | 20426865 |
| MESH:D052016 |
Mucositis |
|
irinotecan |
5.89 | 17159606 |
| MESH:D009362 |
Neoplasm Metastasis |
|
irinotecan |
3.32 | 18259882 |
| MESH:D009447 |
Neuroblastoma |
|
irinotecan |
3.69 | 8761367 |
| MESH:D017599 |
Neuroectodermal Tumors |
|
irinotecan |
5.62 | 8761367 |
| MESH:D013274 |
Stomach Neoplasms |
|
irinotecan |
2.36 | 15723263 |
Related Diseases/Disorders