AutismKB 2.0

Annotation Detail for GABRB2


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Basic Information Top
Gene Symbol:GABRB2 ( MGC119386,MGC119388,MGC119389 )
Gene Full Name: gamma-aminobutyric acid (GABA) A receptor, beta 2
Band: 5q34
Quick LinksEntrez ID:2561; OMIM: 600232; Uniprot ID:GBRB2_HUMAN; ENSEMBL ID: ENSG00000145864; HGNC ID: 4082
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
alcohol consumption
PSYCH
alcohol-dependence
schizophrenia
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|affects reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C036531 2,6-xylenol 2,6-xylenol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
C034047 2-cresol 2-cresol results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]affects binding|increases activity 11399263
C015542 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-ol GABRB2 protein affects the susceptibility to 4,5,6,7-tetrahydroisoxazolo(5,4-c)pyridin-3-olaffects response to substance 12490572
C006477 alphaxalone alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
C006477 alphaxalone alphaxalone promotes the reaction [Muscimol binds to GABRB2 protein]affects binding|increases reaction 8397295
C006477 alphaxalone alphaxalone results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
C006477 alphaxalone GABRB2 protein affects the susceptibility to alphaxaloneaffects response to substance 12939268
D005680 gamma-Aminobutyric Acid 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]affects binding|affects reaction|increases activity 11137757
D005680 gamma-Aminobutyric Acid beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction|increases activity 15588619
D005680 gamma-Aminobutyric Acid Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid GABRA5 protein affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRB2 protein binds to GABRG2 protein]]affects binding|affects reaction|increases activity 10987858
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid affects the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|affects reaction 14637376
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 11812690
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]affects binding|increases activity 11137757
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]increases reaction|increases transport 8161449
D005680 gamma-Aminobutyric Acid isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
D005680 gamma-Aminobutyric Acid Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D005680 gamma-Aminobutyric Acid Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 11812690
D005680 gamma-Aminobutyric Acid alphaxalone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid GABRB2 protein affects the susceptibility to gamma-Aminobutyric Acidaffects response to substance 12939268
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects activity|affects binding 17054655
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]affects cotreatment|increases activity 11123204
D005680 gamma-Aminobutyric Acid [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]affects cotreatment|increases activity 11123204
D005680 gamma-Aminobutyric Acid [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]affects cotreatment|increases activity 11123204
D005680 gamma-Aminobutyric Acid [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]affects cotreatment|increases activity 11123204
D005680 gamma-Aminobutyric Acid [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
D005680 gamma-Aminobutyric Acid Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D005680 gamma-Aminobutyric Acid pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D005680 gamma-Aminobutyric Acid Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005680 gamma-Aminobutyric Acid topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D005680 gamma-Aminobutyric Acid topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|increases activity|increases reaction|increases transport 11123204
D005680 gamma-Aminobutyric Acid Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GABRB2 mRNAaffects expression 16483693
C019264 avermectin avermectin results in decreased activity of GABRB2 proteindecreases activity 10841270
C005790 beta-thujone beta-thujone inhibits the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction|increases activity 15588619
D001761 Bleomycin Bleomycin results in decreased expression of GABRB2 mRNAdecreases expression 15808516
C015044 bromoform bromoform binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects activity|affects binding 12505655
D020001 1-Butanol 1-Butanol affects the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRG2 protein binds to GABRA1 protein binds to GABRB2 protein]]affects binding|affects reaction|increases activity 11137757
D002164 Camphor Camphor promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C006923 carvone carvone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D002712 Chlorides GABRB2 protein results in increased transport of Chloridesincreases transport 8161449
D002712 Chlorides gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]increases reaction|increases transport 8161449
D002712 Chlorides loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
D002712 Chlorides GABRB2 protein affects the reaction [Muscimol results in increased uptake of Chlorides]affects reaction|increases uptake 12490572
D002712 Chlorides [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D002712 Chlorides [gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D002712 Chlorides [gamma-Aminobutyric Acid results in increased activity of [GABRA4 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D002712 Chlorides [gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chloridesaffects cotreatment|increases activity|increases transport 11123204
D002712 Chlorides topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D002712 Chlorides topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
D002712 Chlorides topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|increases activity|increases reaction|increases transport 11123204
C086916 delta-hexachlorocyclohexane delta-hexachlorocyclohexane results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]affects binding|decreases activity 11156579
C086916 delta-hexachlorocyclohexane delta-hexachlorocyclohexane results in decreased activity of [GABRA4 protein binds to GABRB2 protein binds to GABRG2 protein alternative form]affects binding|decreases activity 11156579
D004026 Dieldrin Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D004026 Dieldrin Dieldrin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D004026 Dieldrin Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D007980 Levodopa Levodopa results in decreased expression of GABRB2 mRNAdecreases expression 15837143
D000431 Ethanol GABRB2 protein affects the susceptibility to Ethanolaffects response to substance 12490572
D005045 Etomidate GABRB2 protein affects the susceptibility to Etomidateaffects response to substance 12490572
D005045 Etomidate Etomidate promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D005045 Etomidate Etomidate results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D005045 Etomidate GABRB2 protein affects the susceptibility to Etomidateaffects response to substance 12939268
D005479 Flurazepam GABRB2 protein affects the susceptibility to Flurazepamaffects response to substance 12490572
C022871 isoborneol isoborneol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D001556 Lindane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D001556 Lindane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D008070 Lipopolysaccharides Lipopolysaccharides results in increased expression of GABRB2 mRNAincreases expression 12057914
C066440 loreclezole GABRB2 protein affects the susceptibility to loreclezoleaffects response to substance 10797553
C066440 loreclezole loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB2 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
D008610 Menthol Menthol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
C019466 menthone menthone promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 15588619
D009118 Muscimol GABRB2 protein affects the reaction [Muscimol results in increased uptake of Chlorides]affects reaction|increases uptake 12490572
D009118 Muscimol alphaxalone promotes the reaction [Muscimol binds to GABRB2 protein]affects binding|increases reaction 8397295
D009118 Muscimol GABRB2 protein binds to Muscimolaffects binding 10591412
D009118 Muscimol Muscimol binds to GABRB2 proteinaffects binding 8397295
D009118 Muscimol Pentobarbital affects the reaction [GABRB2 protein binds to Muscimol]affects binding|affects reaction 10591412
D009118 Muscimol Pentobarbital promotes the reaction [Muscimol binds to GABRB2 protein]affects binding|increases reaction 8397295
D010424 Pentobarbital GABRB2 protein affects the susceptibility to Pentobarbitalaffects response to substance 12939268
D010424 Pentobarbital Pentobarbital affects the expression of GABRB2 mRNAaffects expression 10591412
D010424 Pentobarbital Pentobarbital affects the reaction [GABRB2 protein binds to Muscimol]affects binding|affects reaction 10591412
D010424 Pentobarbital Pentobarbital promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D010424 Pentobarbital Pentobarbital promotes the reaction [Muscimol binds to GABRB2 protein]affects binding|increases reaction 8397295
D010424 Pentobarbital Pentobarbital results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D010433 Pentylenetetrazole Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010433 Pentylenetetrazole Pentylenetetrazole inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010433 Pentylenetetrazole Pentylenetetrazole inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D010852 Picrotoxin Picrotoxin inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D010852 Picrotoxin Picrotoxin results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
C025299 polyphenols polyphenols results in decreased expression of GABRB2 mRNAdecreases expression 16293270
C018370 pregnenolone sulfate pregnenolone sulfate inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
C018370 pregnenolone sulfate pregnenolone sulfate results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
D015742 Propofol GABRB2 protein affects the susceptibility to Propofolaffects response to substance 12939268
D015742 Propofol Propofol promotes the reaction [gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 12939268
D015742 Propofol Propofol results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|increases activity 12939268
D015742 Propofol Propofol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
C046308 tert-butylbicyclo-2-benzoate tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C046308 tert-butylbicyclo-2-benzoate tert-butylbicyclo-2-benzoate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Dieldrin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Pentylenetetrazole inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate Picrotoxin inhibits the reaction [tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding 14637376
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to [GABRA2 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|decreases reaction 14637376
D013943 Thymol Thymol results in increased activity of [GABRG2 binds to GABRA1 binds to GABRB2]affects binding|increases activity 11399263
D014050 Toluene Toluene affects the expression of GABRB2 mRNAaffects expression 17108153
C052342 topiramate topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA1 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
C052342 topiramate topiramate inhibits the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA2 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|decreases reaction|increases activity|increases transport 11123204
C052342 topiramate topiramate promotes the reaction [[gamma-Aminobutyric Acid results in increased activity of [GABRA6 protein co-treated with GABRB2 protein co-treated with GABRG2 protein]] which results in increased transport of Chlorides]affects cotreatment|increases activity|increases reaction|increases transport 11123204
D014520 Urethane Urethane promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 11812690
D020888 Vigabatrin Vigabatrin results in decreased expression of GABRB2 mRNAdecreases expression 15869561
D015032 Zinc Zinc inhibits the reaction [gamma-Aminobutyric Acid binds to and affects the activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]]affects activity|affects binding|decreases reaction 17054655
D015032 Zinc Zinc results in decreased activity of [GABRA1 protein binds to GABRB2 protein binds to GABRG2 protein]affects binding|decreases activity 17054655
C049109 zolpidem GABRB2 protein affects the susceptibility to zolpidemaffects response to substance 12490572
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 3.4718926900 17676605
MESH:D000138 Acidosis Ammonium Chloride 8.9618287403
MESH:D000138 Acidosis Ethanol 8.9611192467
MESH:D000169 Acrodermatitis Zinc 4.9517202136 17190629 16889938
MESH:D055371 Acute Lung Injury Bleomycin 8.3117118201
MESH:D055371 Acute Lung Injury Lipopolysaccharides 8.3111850527 18653653
MESH:D000230 Adenocarcinoma Urethane 3.2118316556
MESH:D002282 Adenocarcinoma, Bronchiolo-Alveolar Urethane 5.2515814487
MESH:D000236 Adenoma Urethane 3.7217093202 16926031 10530776 6695378 11497255 10822126 17195641
MESH:D000382 Agricultural Workers' Diseases Lindane 3.9312661182
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.8615451040 15451039
MESH:D000437 Alcoholism topiramate 4.6819331489 18552399 17925516
MESH:D000544 Alzheimer Disease Zinc 2.6516325427 16410023 16580781 17119284
MESH:D000755 Anemia, Sickle Cell Zinc 4.4716916123
MESH:D000853 Anophthalmos Ethanol 4.3815513904
MESH:D000860 Anoxia Bleomycin 4.9515782499
MESH:D001008 Anxiety Disorders Ethanol 8.2211141031
MESH:D001008 Anxiety Disorders Pentobarbital 8.2218313124 11141031
MESH:D001249 Asthma Zinc 2.8117085522
MESH:D001259 Ataxia 1-Butanol 5.167820390
MESH:D001836 Body Weight Changes 2-cresol 6.2512820538
MESH:D001930 Brain Injuries Zinc 4.2517109824
MESH:D001943 Breast Neoplasms Dieldrin 3.0311859874 15770527
MESH:D001943 Breast Neoplasms Lindane 3.0314688026
MESH:D002056 Burns Ethanol 4.2116374292
MESH:D006528 Carcinoma, Hepatocellular Ethanol 2.3515763234 15289165 18788625
MESH:D002294 Carcinoma, Squamous Cell Bleomycin 4.866189445
MESH:D002294 Carcinoma, Squamous Cell Zinc 4.8616543248
MESH:D006332 Cardiomegaly Ethanol 3.1819332462
MESH:D002318 Cardiovascular Diseases Zinc 3.3416936243
MESH:D002471 Cell Transformation, Neoplastic bromoform 5.0718075178
MESH:D002547 Cerebral Palsy Toluene 5.399294310
MESH:D002659 Child Development Disorders, Pervasive topiramate 3.9215650499
MESH:D002971 Cleft Lip Ethanol 3.3415513904
MESH:D002972 Cleft Palate Ethanol 5.8715513904
MESH:D002972 Cleft Palate Urethane 5.8712810352
MESH:D003110 Colonic Neoplasms polyphenols 2.5916293270
MESH:D019465 Craniofacial Abnormalities Ethanol 3.7815451039 11873399 19302082 15451040 10194807 11198716 15513904
MESH:D019465 Craniofacial Abnormalities Toluene 3.789294310
MESH:D019465 Craniofacial Abnormalities Zinc 3.7819302082
MESH:D003643 Death Pentylenetetrazole 12.356431079
MESH:D003643 Death Toluene 12.356431079
MESH:D003920 Diabetes Mellitus Zinc 3.8216479319
MESH:D003924 Diabetes Mellitus, Type 2 topiramate 3.5816979414
MESH:D056486 Drug-Induced Liver Injury Ethanol 3.8911566570
MESH:D056486 Drug-Induced Liver Injury polyphenols 3.8919370779
MESH:D004409 Dyskinesia, Drug-Induced Levodopa 5.903690436 15893579
MESH:D004487 Edema Bleomycin 3.8617118201
MESH:D019446 Endotoxemia Lipopolysaccharides 3.9417637181 15328337 15821434
MESH:D004827 Epilepsy topiramate 4.0819148780
MESH:D004832 Epilepsy, Absence Pentylenetetrazole 5.266426943
MESH:D004833 Epilepsy, Temporal Lobe topiramate 5.8116499746
MESH:D004938 Esophageal Neoplasms Ethanol 4.4616704527
MESH:D004938 Esophageal Neoplasms Zinc 4.4616543248
MESH:D005234 Fatty Liver Ethanol 3.3416409862 18620774 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.2017920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.8416946407 15451040 15513904 10194807
MESH:D005334 Fever Lipopolysaccharides 3.629205823 11852909
MESH:D005756 Gastritis Ethanol 10.0015046732
MESH:D005756 Gastritis Zinc 10.0017241300
MESH:D006130 Growth Disorders Zinc 3.6617217573
MESH:D006331 Heart Diseases Urethane 3.9216046796
MESH:D006333 Heart Failure Zinc 3.3217162251
MESH:D006335 Heart Injuries Zinc 5.3117074742
MESH:D016481 Helicobacter Infections Zinc 4.1117241300
MESH:D006463 Hemolytic-Uremic Syndrome Lipopolysaccharides 3.9916366002
MESH:D006527 Hepatolenticular Degeneration Zinc 4.2517276780
MESH:D006689 Hodgkin Disease Bleomycin 4.0017606976 15147373 18501091
MESH:D006930 Hyperalgesia Ethanol 3.3618783367
MESH:D020138 Hyperhomocysteinemia Levodopa 5.3116275827 16787708
MESH:D007247 Infertility, Female Dieldrin 4.5210630421
MESH:D007249 Inflammation Bleomycin 7.2417118201
MESH:D007249 Inflammation Lipopolysaccharides 7.2417237260 17963957 12878042 9205823 17255318
MESH:D007249 Inflammation polyphenols 7.2416366677
MESH:D019189 Iron Metabolism Disorders Lipopolysaccharides 4.2117255318
MESH:D007511 Ischemia Zinc 4.1916584753
MESH:D007569 Jaw Abnormalities Ethanol 4.0015513904
MESH:D007674 Kidney Diseases Zinc 3.0616960431
MESH:D007676 Kidney Failure, Chronic Zinc 4.0116518626
MESH:D007859 Learning Disorders Ethanol 3.7715451040
MESH:D007970 Leukopenia Lipopolysaccharides 4.2415821434
MESH:D017880 Limb Deformities, Congenital Ethanol 3.4917676605
MESH:D008103 Liver Cirrhosis Ethanol 3.1115289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.6418295389
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 2.7018166357
MESH:D008106 Liver Cirrhosis, Experimental Lipopolysaccharides 2.7012878042
MESH:D008107 Liver Diseases Lindane 4.251715830
MESH:D008107 Liver Diseases polyphenols 4.2516698588
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.2117347304 17207112
MESH:D008113 Liver Neoplasms Dieldrin 4.809539021 8742319
MESH:D008113 Liver Neoplasms Urethane 4.8017559639 17093202 16391232
MESH:D055370 Lung Injury Lipopolysaccharides 3.5721114838
MESH:D008175 Lung Neoplasms Bleomycin 3.216189445
MESH:D008175 Lung Neoplasms Urethane 3.2114587096 16289808 11497255 6695378 12466968 15166089 16788158 10822126 10779650 16926031 16391232 11323394 12117781 11807781 16007126 16204055 17195641 11893704 16337739 10997738 17093202 15902970 11246140 17255336 11307925 11074608 15136453 11062179 7750092 11992545 11552296 12765245 11544531 12957351 10530776
MESH:D008325 Mammary Neoplasms, Experimental Zinc 3.0112773700
MESH:D008545 Melanoma Bleomycin 3.1915577320
MESH:D008569 Memory Disorders Ethanol 3.7618411066 15451040
MESH:D008607 Mental Retardation Toluene 3.489294310
MESH:D008881 Migraine Disorders topiramate 4.2518759728 18765137 16942474 18803445
MESH:D019957 Motor Skills Disorders Toluene 4.819294310
MESH:D009369 Neoplasms Dieldrin 7.328820588
MESH:D009369 Neoplasms Lindane 7.3216818664 12807735
MESH:D009369 Neoplasms Urethane 7.3215625555
MESH:D009374 Neoplasms, Experimental Urethane 4.2415582191
MESH:D010051 Ovarian Neoplasms Urethane 3.3016391232
MESH:D010190 Pancreatic Neoplasms Ethanol 2.8012384795
MESH:D010300 Parkinson Disease Dieldrin 5.8011445065 17291500 16809432 11181820 16112328
MESH:D010300 Parkinson Disease Levodopa 5.807566641 19594199 18328768 11432539 20334432
MESH:D020734 Parkinsonian Disorders Levodopa 5.278817341 11246459 18722529
MESH:D010911 Pituitary Neoplasms Urethane 4.9716391232
MESH:D011014 Pneumonia Bleomycin 9.9716317386 17071938 18024389
MESH:D011014 Pneumonia Lipopolysaccharides 9.9712224865 11605937
MESH:D011225 Pre-Eclampsia Zinc 3.8217114810
MESH:D011471 Prostatic Neoplasms Lindane 4.0214688026 12661182
MESH:D011471 Prostatic Neoplasms Zinc 4.0216700911 12429649 16606632 16517595
MESH:D011654 Pulmonary Edema Bleomycin 4.8615808516
MESH:D011658 Pulmonary Fibrosis Bleomycin 3.6817177178 12624602 15322207 15541506 21435439 17241526 16115399 16314464 18162602 18008008 14609568 11554783 17434272 12574379
MESH:D012004 Rectal Neoplasms bromoform 5.9117535441
MESH:D012021 Reflex, Abnormal Pentobarbital 5.5710930210
MESH:D012130 Respiratory Hypersensitivity Lipopolysaccharides 3.4310835634
MESH:D012162 Retinal Degeneration Zinc 3.7916584753
MESH:D012559 Schizophrenia marker/mechanism 18583979
MESH:C537537 Segawa syndrome, autosomal recessive Levodopa 6.248817341
MESH:D012640 Seizures Ethanol 36.709754883
MESH:D012640 Seizures Lindane 36.707539098 12842176 15475178
MESH:D012640 Seizures loreclezole 36.7010454489
MESH:D012640 Seizures Pentobarbital 36.709754883 10087439
MESH:D012640 Seizures Pentylenetetrazole 36.702616065 8954991 6431079 3352866 19660546 3037702 15475178 18657176 18164287 16054440
MESH:D012640 Seizures Picrotoxin 36.708954991 8635557
MESH:D012640 Seizures Toluene 36.706431079 9294310
MESH:D012640 Seizures topiramate 36.7016499746
MESH:D012640 Seizures Vigabatrin 36.709844417 10454489
MESH:D012640 Seizures zolpidem 36.709754883
MESH:D012878 Skin Neoplasms Urethane 3.4911807781
MESH:D012893 Sleep Disorders zolpidem 5.9019395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Flurazepam 10.1115341891
MESH:D007319 Sleep Initiation and Maintenance Disorders zolpidem 10.119066939 15341891 17225163
MESH:D013274 Stomach Neoplasms Ethanol 2.3018456281
MESH:D013276 Stomach Ulcer Ethanol 3.1416755016 17918041 9211565 11906479 9562338 17189318
MESH:D013375 Substance Withdrawal Syndrome Ethanol 14.539754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 14.5311529278 9754883
MESH:D013375 Substance Withdrawal Syndrome zolpidem 14.539754883
MESH:D013705 Temporomandibular Joint Disorders polyphenols 4.7917997062
MESH:D013733 Testicular Diseases Toluene 4.5010514026 10048760
MESH:D013742 Tetanus Propofol 5.972903605
MESH:D013921 Thrombocytopenia Lipopolysaccharides 3.7715821434
MESH:D014062 Tongue Neoplasms Zinc 4.0016543248
MESH:D014202 Tremor 2-cresol 5.9112820538
MESH:D019043 Vascular Neoplasms Urethane 5.4510620525
MESH:D015431 Weight Loss Bleomycin 5.1912624602
Pathway ID Pathway Name
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:13685 Synaptic Transmission
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28496
    • No data
    Releated disease ID Related disease Name
    PA447268tardive dyskinesia
    PA447216Schizophrenia
    PA443309Alcoholism
    Releated drug ID Related drug Name
    PA449283diazepam
    PA164781320flunitrazepam
    PA164743987etomidate
    PA164783813adinazolam
    PA448333alprazolam
    PA10402benzodiazepine derivatives
    PA10035bromazepam
    PA448932chlordiazepoxide
    PA164748034cinolazepam
    PA10888clobazam
    PA449050clonazepam
    PA164749297clorazepate
    PA449502estazolam
    PA449681flurazepam
    PA164746526halazepam
    PA164749385ketazolam
    PA450267lorazepam
    PA450496midazolam
    PA10242nitrazepam
    PA450731oxazepam
    PA164776668prazepam
    PA164744373quazepam
    PA451608temazepam
    PA451753triazolam
    PA449659flumazenil
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00186 potentiator Lorazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Benzodiazepines;GABA Modulators
    DB00189 agonist Ethchlorvynol Hypnotics and Sedatives
    DB00231 partial agonist Temazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00349 potentiator Clobazam Anticonvulsants;Benzodiazepines
    DB00404 potentiator Alprazolam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB00475 potentiator Pro Chlorax Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00546 potentiator Adinazolam Anti-anxiety Agents;Antidepressive Agents
    DB00628 potentiator Clorazepate Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB00683 potentiator Midazolam Anti-anxiety Agents;Hypnotics and Sedatives;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous
    DB00690 potentiator Flurazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00801 potentiator Halazepam Anti-anxiety Agents;Muscle Relaxants;Benzodiazepines;Sedative
    DB00818 potentiator Propofol Free Radical Scavengers;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Anesthetics, Intravenous
    DB00829 potentiator Diazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous;Muscle Relaxants, Central
    DB00842 potentiator Oxazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00897 potentiator Triazolam Anti-anxiety Agents;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB01068 potentiator Clonazepam Anticonvulsants;Benzodiazepines;GABA Modulators
    DB01215 potentiator Estazolam Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB01381 negative modulator Ginkgo biloba
    DB01558 potentiator Bromazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB01559 potentiator Clotiazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;Benzodiazepines
    DB01567 potentiator Fludiazepam Anti-anxiety Agents;Benzodiazepines
    DB01588 potentiator Prazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB01594 potentiator Cinolazepam Anticonvulsants;Benzodiazepines;Sedatives and Hypnotics
    DB01595 potentiator Nitrazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;GABA Modulators
    DB06716 potentiator Fospropofol Hypnotics and Sedatives;Anesthetics, Intravenous
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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