AutismKB 2.0

Annotation Detail for GABRB3


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:GABRB3 ( ECA5,MGC9051 )
Gene Full Name: gamma-aminobutyric acid (GABA) A receptor, beta 3
Band: 15q12
Quick LinksEntrez ID:2562; OMIM: 137192; Uniprot ID:GBRB3_HUMAN; ENSEMBL ID: ENSG00000166206; HGNC ID: 4083
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04080Neuroactive ligand-receptor interaction
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
PSYCH
NEUROLOGICAL
post-traumatic stress disorder
Autism
Cognitive performance
Desease Name
Cognitive performance
Desease Name
Insomnia
Epilepsy, childhood absence, susceptibility to, 5
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 proteinaffects binding 16537435
11489356
11312652
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Endosulfan inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane fipronil inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
C091518 1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
C098123 3,3-bis(trifluoromethyl)bicyclo(2.2.1)heptane-2,2-dicarbonitrile 3,3-bis(trifluoromethyl)bicyclo(2.2.1)heptane-2,2-dicarbonitrile binds to GABRB3 proteinaffects binding 16537435
C006477 alphaxalone alphaxalone promotes the reaction [Muscimol binds to GABRB3 protein]affects binding|increases reaction 8397295
D005680 gamma-Aminobutyric Acid Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 8632757
D005680 gamma-Aminobutyric Acid gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]increases reaction|increases transport 8161449
D005680 gamma-Aminobutyric Acid loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
D005680 gamma-Aminobutyric Acid Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 8632757
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GABRB3 mRNAaffects expression 16483693
D001640 Bicuculline Bicuculline results in decreased expression of GABRB3 mRNAdecreases expression 9600394
C054626 bretazenil bretazenil binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C054626 bretazenil bretazenil binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D002712 Chlorides GABRB3 protein results in increased transport of Chloridesincreases transport 8161449
D002712 Chlorides gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]increases reaction|increases transport 8161449
D002712 Chlorides loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
C021604 CL 218872 CL 218872 binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D003024 Clozapine Clozapine results in increased expression of GABRB3 mRNAincreases expression 18923069
D003975 Diazepam Diazepam results in increased expression of GABRB3 mRNAincreases expression 15802192
D004026 Dieldrin Dieldrin results in decreased expression of GABRB3 mRNAdecreases expression 9600394
D004026 Dieldrin Dieldrin results in increased expression of GABRB3 mRNAincreases expression 9302086
D004726 Endosulfan Endosulfan binds to GABRB3 proteinaffects binding 11489356
16537435
D004726 Endosulfan Endosulfan inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
D004958 Estradiol Estradiol results in increased expression of GABRB3 mRNAincreases expression 16000229
D005045 Etomidate GABRB3 protein results in increased susceptibility to Etomidateincreases response to substance 9523823
C082360 fipronil fipronil binds to GABRB3 proteinaffects binding 11489356
16537435
C082360 fipronil fipronil inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
D005442 Flumazenil Flumazenil binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D005442 Flumazenil Flumazenil binds to [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding 8632757
D005442 Flumazenil Flumazenil promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 8632757
D005445 Flunitrazepam Flunitrazepam binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D018682 GABA Agents GABA Agents binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D018682 GABA Agents GABA Agents binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D006220 Haloperidol Haloperidol results in increased expression of GABRB3 mRNAincreases expression 18923069
C063822 L 663581 L 663581 binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C063822 L 663581 L 663581 binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
D001556 Lindane Lindane binds to GABRB3 proteinaffects binding 11489356
16537435
D001556 Lindane Lindane inhibits the reaction [1-(4-ethynylphenyl)-4-propyl-2,6,7-trioxabicyclo(2.2.2)octane binds to GABRB3 protein]affects binding|decreases reaction 11312652
C066440 loreclezole GABRB3 protein affects the susceptibility to loreclezoleaffects response to substance 10797553
C066440 loreclezole loreclezole promotes the reaction [gamma-Aminobutyric Acid promotes the reaction [GABRB3 protein results in increased transport of Chlorides]]increases reaction|increases transport 8161449
D008874 Midazolam GABRB3 protein results in increased susceptibility to Midazolamincreases response to substance 9523823
D009118 Muscimol alphaxalone promotes the reaction [Muscimol binds to GABRB3 protein]affects binding|increases reaction 8397295
D009118 Muscimol Muscimol binds to GABRB3 proteinaffects binding 8397295
D009118 Muscimol Pentobarbital promotes the reaction [Muscimol binds to GABRB3 protein]affects binding|increases reaction 8397295
D010424 Pentobarbital Pentobarbital promotes the reaction [Muscimol binds to GABRB3 protein]affects binding|increases reaction 8397295
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GABRB3 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of GABRB3 mRNAincreases expression 19482888
C033457 phenobarbital quinidine phenobarbital quinidine results in increased expression of GABRB3 mRNAincreases expression 15802192
C022961 picrotoxinin picrotoxinin binds to GABRB3 proteinaffects binding 16537435
C042957 Ro 15-4513 Ro 15-4513 binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
C042957 Ro 15-4513 Ro 15-4513 promotes the reaction [gamma-Aminobutyric Acid binds to and results in increased activity of [GABRA6 protein binds to GABRB3 protein binds to GABRG2 protein]]affects binding|increases activity|increases reaction 8632757
C037476 tert-butylbicyclophosphorothionate tert-butylbicyclophosphorothionate binds to GABRB3 proteinaffects binding 16537435
D014050 Toluene Toluene affects the expression of GABRB3 mRNAaffects expression 17108153
D014801 Vitamin A Vitamin A results in increased expression of GABRB3 mRNAincreases expression 17225872
C049109 zolpidem zolpidem binds to and results in increased activity of [GABRA1 protein binds to GABRB3 protein binds to GABRG2 protein]affects binding|increases activity 8632757
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.116195326
MESH:D000015 Abnormalities, Multiple Vitamin A 4.5610992263
MESH:D000138 Acidosis Ammonium Chloride 3.2218287403
MESH:D000230 Adenocarcinoma Estradiol 2.0111473722
MESH:D018248 Adenoma, Liver Cell Phenobarbital 3.6317620307
MESH:D000380 Agranulocytosis Clozapine 4.7212649775 16160616 14617031
MESH:D000382 Agricultural Workers' Diseases Lindane 4.0412661182
MESH:D000740 Anemia Vitamin A 4.2316960172
MESH:D018798 Anemia, Iron-Deficiency Vitamin A 4.5016960172
MESH:D017204 Angelman Syndrome marker/mechanism 15878204
MESH:D001008 Anxiety Disorders Diazepam 8.9618313124 16284244
MESH:D001008 Anxiety Disorders Pentobarbital 8.9618313124 11141031
MESH:D001249 Asthma Vitamin A 3.2516732791
MESH:D001321 Autistic Disorder marker/mechanism 9545402
MESH:D001321 Autistic Disorder Haloperidol 2.7719368416 18080171
MESH:D001943 Breast Neoplasms Dieldrin 2.1815770527 11859874
MESH:D001943 Breast Neoplasms Estradiol 2.1818497071 12948864 19861407 17289903 17261762 16675129 17018787 14630087
MESH:D001943 Breast Neoplasms Lindane 2.1814688026
MESH:D001997 Bronchopulmonary Dysplasia Vitamin A 5.2617377406 17426644
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1216111702
MESH:D006528 Carcinoma, Hepatocellular Estradiol 2.8416924424
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 2.8417173139 20007298 6705139 20935162 1701930
MESH:D002375 Catalepsy Haloperidol 4.5715215559 1977408
MESH:D002471 Cell Transformation, Neoplastic Estradiol 2.5418566989
MESH:D002493 Central Nervous System Diseases Phenobarbital 3.924080065
MESH:D002547 Cerebral Palsy Toluene 5.519294310
MESH:D015362 Child Nutrition Disorders Vitamin A 5.1316153327
MESH:D002779 Cholestasis Vitamin A 4.0516175620
MESH:D002972 Cleft Palate Diazepam 6.483629520
MESH:D002972 Cleft Palate Vitamin A 6.4816054864
MESH:D003072 Cognition Disorders Clozapine 4.6317123785
MESH:D003110 Colonic Neoplasms Vitamin A 2.9817219422 16267017
MESH:D019465 Craniofacial Abnormalities marker/mechanism 15878204
MESH:D019465 Craniofacial Abnormalities Toluene 3.309294310
MESH:D019465 Craniofacial Abnormalities Vitamin A 3.3010992263
MESH:D003490 Cyanosis Endosulfan 5.217900959
MESH:D003643 Death Toluene 5.326431079
MESH:D016757 Death, Sudden, Cardiac Haloperidol 4.5320210726
MESH:D003704 Dementia Haloperidol 4.2811575062
MESH:D003922 Diabetes Mellitus, Type 1 Vitamin A 3.4016506275
MESH:D003924 Diabetes Mellitus, Type 2 Clozapine 2.8916402076
MESH:D003928 Diabetic Nephropathies Estradiol 3.1319279558
MESH:D006970 Disorders of Excessive Somnolence Clozapine 5.2115331141
MESH:D015352 Dry Eye Syndromes Vitamin A 5.4616146918
MESH:D050171 Dyslipidemias Clozapine 3.9416402076
MESH:D004417 Dyspnea Endosulfan 4.933388749 7900959
MESH:D020920 Dyssomnias marker/mechanism
MESH:D004421 Dystonia Diazepam 9.991851702
MESH:D004421 Dystonia Phenobarbital 9.991851702
MESH:C538011 Eales disease Vitamin A 5.279068938
MESH:D004480 Ectromelia Vitamin A 5.4816054864
MESH:D004646 Emphysema Endosulfan 6.217900959
MESH:D016889 Endometrial Neoplasms Estradiol 2.7611473722 18566989 19148513
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 3.783659116
MESH:D004828 Epilepsies, Partial Diazepam 9.423922381
MESH:D004828 Epilepsies, Partial Phenobarbital 9.423922381 11558140
MESH:D004827 Epilepsy marker/mechanism 15878204
MESH:D004827 Epilepsy Diazepam 6.67821787
MESH:D004827 Epilepsy Phenobarbital 6.6720417680
MESH:D004832 Epilepsy, Absence marker/mechanism
MESH:D004832 Epilepsy, Absence Diazepam 8.526426943 6401628
MESH:D004832 Epilepsy, Absence Phenobarbital 8.526401628
OMIM:612269 EPILEPSY, CHILDHOOD ABSENCE, SUSCEPTIBILITY TO, 5 marker/mechanism
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 3.927750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 3.683659116
MESH:D005327 Fetal Resorption Vitamin A 5.0216054864
MESH:D006330 Heart Defects, Congenital Vitamin A 3.7216080930 10992263
MESH:D006470 Hemorrhage Endosulfan 4.997900959
MESH:D006529 Hepatomegaly Phenobarbital 3.1616109766
MESH:D006548 Hernia, Diaphragmatic Vitamin A 3.5017436238 16490937 16863852 16292552 15707848 16877224
MESH:D006558 Herpes Genitalis Estradiol 4.6915709030
MESH:D015658 HIV Infections Vitamin A 3.6416960176
MESH:D006679 HIV Seropositivity Vitamin A 5.2617209195
MESH:D019584 Hot Flashes Estradiol 3.4117088409
MESH:D006948 Hyperkinesis Clozapine 4.5716046005
MESH:D006986 Hypervitaminosis A Vitamin A 5.8216054864
MESH:D007247 Infertility, Female Dieldrin 4.6210630421
MESH:D007248 Infertility, Male Endosulfan 4.078588293 9432128
MESH:D007333 Insulin Resistance Estradiol 2.7516393666 16627594
MESH:D019586 Intracranial Hypertension Vitamin A 5.4815955940
MESH:D007674 Kidney Diseases Estradiol 2.3915618244
MESH:D007680 Kidney Neoplasms Estradiol 2.7115610895
MESH:D007859 Learning Disorders Endosulfan 4.778157075
MESH:D017880 Limb Deformities, Congenital Vitamin A 4.0716054864
MESH:D008064 Lipidoses Clozapine 3.7217567588
MESH:D008103 Liver Cirrhosis Phenobarbital 6.4021047994
MESH:D008103 Liver Cirrhosis Vitamin A 6.4016256175
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 2.7214716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Vitamin A 2.7216248980
MESH:D008107 Liver Diseases Lindane 6.261715830
MESH:D008107 Liver Diseases Phenobarbital 6.2619363144
MESH:D008107 Liver Diseases Vitamin A 6.2616175620
MESH:D008108 Liver Diseases, Alcoholic Vitamin A 4.8216762690
MESH:D008113 Liver Neoplasms Dieldrin 4.588742319 9539021
MESH:D008113 Liver Neoplasms Phenobarbital 4.588742319 19812893 21047994 19073162 19482888 15975961
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 5.676150874 1399818 18308698 17172636 2563599
MESH:D008114 Liver Neoplasms, Experimental Vitamin A 5.6717113696
MESH:D008171 Lung Diseases Vitamin A 3.8716863852
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.3511807958 17203775 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.1419453300
MESH:D001523 Mental Disorders Clozapine 7.2416856516
MESH:D001523 Mental Disorders Haloperidol 7.2416856516
MESH:D008607 Mental Retardation Toluene 3.539294310
MESH:D024821 Metabolic Syndrome X Clozapine 4.1419142101
MESH:D008924 Mite Infestations fipronil 6.6316884176
MESH:D019957 Motor Skills Disorders Toluene 4.929294310
MESH:D009101 Multiple Myeloma Vitamin A 3.8116374440
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.0216810080
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.1317484760
MESH:D009369 Neoplasms Dieldrin 5.268820588
MESH:D009369 Neoplasms Lindane 5.2612807735 16818664
MESH:D009389 Neovascularization, Pathologic Estradiol 3.3917289903
MESH:D009421 Nervous System Malformations Estradiol 3.3311399458 16427766
MESH:D009436 Neural Tube Defects Vitamin A 3.8417400914
MESH:D009765 Obesity Clozapine 2.9318515891 19142110
MESH:D010018 Osteomalacia Phenobarbital 4.0217016548
MESH:D010051 Ovarian Neoplasms Estradiol 2.1119401270
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.3716965848
MESH:D010300 Parkinson Disease Dieldrin 3.4016112328 11181820 16809432 17291500 11445065
MESH:D011230 Precancerous Conditions Phenobarbital 3.342563599
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5820887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.6816740699
MESH:D011471 Prostatic Neoplasms Lindane 3.6812661182 14688026
MESH:D019310 Pseudolymphoma Phenobarbital 4.1512752131
MESH:D011595 Psychomotor Agitation Haloperidol 4.6211575062
MESH:D011618 Psychotic Disorders Clozapine 8.3515331141
MESH:D011618 Psychotic Disorders Haloperidol 8.3511575062
MESH:D012021 Reflex, Abnormal Pentobarbital 5.6810930210
MESH:D012127 Respiratory Distress Syndrome, Newborn Vitamin A 5.4616877224
MESH:D012559 Schizophrenia Clozapine 3.9120521326 17123785 11763009 19369910 18855531 17667964 20580759 20168265 20107430 20521320 17726453 11151749 20452607 16141801 18806925
MESH:D012559 Schizophrenia Haloperidol 3.9118513383 19369910 1830565 20107430
MESH:D012640 Seizures Diazepam 38.6110087439 15946322 9754883
MESH:D012640 Seizures Endosulfan 38.6110698677 7539098
MESH:D012640 Seizures fipronil 38.6110698677
MESH:D012640 Seizures Lindane 38.6112842176 7539098 15475178
MESH:D012640 Seizures loreclezole 38.6110454489
MESH:D012640 Seizures Midazolam 38.6110087439
MESH:D012640 Seizures Pentobarbital 38.619754883 10087439
MESH:D012640 Seizures Phenobarbital 38.6116876388 11442880 4039156 3137016
MESH:D012640 Seizures Toluene 38.616431079 9294310
MESH:D012640 Seizures zolpidem 38.619754883
MESH:D003294 Seizures, Febrile Phenobarbital 4.486407741
MESH:D012871 Skin Diseases Vitamin A 3.2718709164
MESH:D012893 Sleep Disorders Midazolam 10.926138072
MESH:D012893 Sleep Disorders zolpidem 10.9219395429
MESH:D007319 Sleep Initiation and Maintenance Disorders Midazolam 10.176138071
MESH:D007319 Sleep Initiation and Maintenance Disorders zolpidem 10.1717225163 15341891 9066939
MESH:D013375 Substance Withdrawal Syndrome Diazepam 15.279754883
MESH:D013375 Substance Withdrawal Syndrome Pentobarbital 15.2711529278 9754883
MESH:D013375 Substance Withdrawal Syndrome zolpidem 15.279754883
MESH:D017180 Tachycardia, Ventricular Haloperidol 4.3820210726
MESH:D013733 Testicular Diseases Toluene 4.6210048760 10514026
MESH:D013742 Tetanus Midazolam 6.292903605
MESH:D013964 Thyroid Neoplasms Phenobarbital 2.801399818
MESH:D013978 Tibial Fractures Estradiol 4.3419048282
MESH:D014802 Vitamin A Deficiency Vitamin A 4.9616960172 16175781 16146918
MESH:D015430 Weight Gain Clozapine 4.1820521320 20107430 16402076 17502770 16141801 20564506
MESH:D015431 Weight Loss Clozapine 4.7417933447
Pathway ID Pathway Name
KEGG:04080 Neuroactive ligand-receptor interaction
REACT:13685 Synaptic Transmission
REACT:15518 Transmembrane transport of small molecules
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28497
    • No data
    Releated disease ID Related disease Name
    PA447198Autistic Disorder
    PA444070Epilepsy, Absence
    PA443309Alcoholism
    No data
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00186 potentiator Lorazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Benzodiazepines;GABA Modulators
    DB00189 agonist Ethchlorvynol Hypnotics and Sedatives
    DB00231 potentiator Temazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00349 potentiator Clobazam Anticonvulsants;Benzodiazepines
    DB00404 potentiator Alprazolam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB00475 potentiator Pro Chlorax Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB00546 potentiator Adinazolam Anti-anxiety Agents;Antidepressive Agents
    DB00592 agonist Ripercol Horse Wormer Anthelmintics;Antinematodal Agents
    DB00602 agonist Heel 170 Tab Anthelmintics;Antiprotozoal Agents;Antinematodal Agents
    DB00628 potentiator Clorazepate Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB00683 potentiator Midazolam Anti-anxiety Agents;Hypnotics and Sedatives;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous
    DB00690 potentiator Flurazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00801 potentiator Halazepam Anti-anxiety Agents;Muscle Relaxants;Benzodiazepines;Sedative
    DB00818 potentiator Propofol Free Radical Scavengers;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Anesthetics, Intravenous
    DB00829 potentiator Diazepam Anti-anxiety Agents;Hypnotics and Sedatives;Antiemetics;Anticonvulsants;Adjuvants, Anesthesia;GABA Modulators;Anesthetics, Intravenous;Muscle Relaxants, Central
    DB00842 partial agonist Oxazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB00897 potentiator Triazolam Anti-anxiety Agents;Benzodiazepines;Adjuvants, Anesthesia;GABA Modulators
    DB01068 potentiator Clonazepam Anticonvulsants;Benzodiazepines;GABA Modulators
    DB01215 potentiator Estazolam Anti-anxiety Agents;Anticonvulsants;GABA Modulators
    DB01558 potentiator Bromazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB01559 potentiator Clotiazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;Benzodiazepines
    DB01567 potentiator Fludiazepam Anti-anxiety Agents;Benzodiazepines
    DB01588 potentiator Prazepam Anti-anxiety Agents;Hypnotics and Sedatives;GABA Modulators
    DB01589 potentiator Quazepam Anti-anxiety Agents;Hypnotics and Sedatives;Benzodiazepines;GABA Modulators
    DB01594 potentiator Cinolazepam Anticonvulsants;Benzodiazepines;Sedatives and Hypnotics
    DB01595 potentiator Nitrazepam Anti-anxiety Agents;Hypnotics and Sedatives;Anticonvulsants;GABA Modulators
    DB06716 potentiator Fospropofol Hypnotics and Sedatives;Anesthetics, Intravenous
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


    Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved