AutismKB 2.0

Annotation Detail for NUDT14


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NUDT14 ( UGPP,UGPPase )
Gene Full Name: nudix (nucleoside diphosphate linked moiety X)-type motif 14
Band: 14q32.33
Quick LinksEntrez ID:256281; OMIM: 609219; Uniprot ID:NUD14_HUMAN; ENSEMBL ID: ENSG00000183828; HGNC ID: 20141
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of NUDT14 mRNAaffects expression 21346803
D001564 Benzo(a)pyrene Benzo(a)pyrene results in increased expression of NUDT14 mRNAincreases expression 20106945
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of NUDT14 mRNAdecreases expression 20127859
D004041 Dietary Fats Dietary Fats results in increased expression of NUDT14 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of NUDT14 mRNAincreases expression 18042831
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0620127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.866695378
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.6419183758
MESH:D001161 Arteriosclerosis Dietary Fats 4.4515238619
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0720146248 17474063
MESH:D001943 Breast Neoplasms Dietary Fats 2.0720435547
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 1.7916705839
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.5818551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 2.0518551238 21346803
MESH:D050171 Dyslipidemias Dietary Fats 3.7318367378
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0816530937
MESH:D005234 Fatty Liver Dietary Fats 3.6618296743 17967931 19551842 19004024
MESH:D005355 Fibrosis Dietary Fats 4.0818296743
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8320471113
MESH:D006937 Hypercholesterolemia Dietary Fats 4.0221332399
MESH:D006949 Hyperlipidemias Dietary Fats 4.0821332399
MESH:D007249 Inflammation Dietary Fats 2.6020412841
MESH:D007333 Insulin Resistance Dietary Fats 3.3411836018 18457598
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 3.3216705839
MESH:D008103 Liver Cirrhosis Dietary Fats 3.0718296743
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 2.1520195826 21137059
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5717053015 18569708 20135361 18816296 20064080 20464547 18520028 6695378 20869020
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.5016381670
MESH:D009336 Necrosis 2,4-dinitrotoluene 4.4918551238
MESH:D009369 Neoplasms Benzo(a)pyrene 2.3311141357
MESH:D009765 Obesity Dietary Fats 2.3621332399 20518802 17217161 16723640 18674790 18457598 19632207 11836018 20132043
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.8212819281 16049721
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 2.9117292933
MESH:D012640 Seizures 2,4-dinitrotoluene 2.7918551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5219755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3916049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.3917053015
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.9510091137
MESH:D015430 Weight Gain Dietary Fats 4.1116723640
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018