Annotation Detail for ST6GALNAC3
Basic Information Top
| Gene Symbol: | ST6GALNAC3 ( FLJ13669,FLJ27239,PRO7177,SIAT7C,ST6GALNACIII,STY ) |
|---|---|
| Gene Full Name: | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 |
| Band: | 1p31.1 |
| Quick Links | Entrez ID:256435; OMIM: 610133; Uniprot ID:SIA7C_HUMAN; ENSEMBL ID: ENSG00000184005; HGNC ID: 19343 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C472791 | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid | 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in decreased expression of ST6GALNAC3 mRNA | decreases expression | 16788091 |
| D000082 | Acetaminophen | Acetaminophen affects the expression of ST6GALNAC3 mRNA | affects expression | 17562736 |
| C006253 | pirinixic acid | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of ST6GALNAC3 mRNA | affects binding|increases activity|increases expression | 19710929 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D055371 | Acute Lung Injury | pirinixic acid | 3.64 | 18653653 | |
| MESH:D018248 | Adenoma, Liver Cell | pirinixic acid | 4.22 | 16434500 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001778 | Blood Coagulation Disorders | pirinixic acid | 3.63 | 19483382 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D002779 | Cholestasis | pirinixic acid | 3.15 | 19176532 | |
| MESH:D003876 | Dermatitis, Atopic | pirinixic acid | 2.59 | 18249437 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19085960 12540782 12958197 11739529 15968718 11287661 19164858 12153990 19739265 19420014 12392966 11529661 16485898 18071297 12705907 10915739 11421492 12594235 17522070 14550746 15619225 18713872 16109766 10663392 11461765 17906064 19416960 11743745 16781746 14725611 19923254 16227642 16081117 11834606 19370779 10774834 14986274 16393943 16177239 17562736 2444490 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004487 | Edema | pirinixic acid | 2.96 | 12083418 | |
| MESH:D005234 | Fatty Liver | pirinixic acid | 3.25 | 20131406 19236843 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006333 | Heart Failure | pirinixic acid | 2.78 | 20558911 | |
| MESH:D006529 | Hepatomegaly | pirinixic acid | 3.64 | 19772884 16221962 19176532 18467677 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D006943 | Hyperglycemia | pirinixic acid | 3.63 | 20558911 | |
| MESH:D007333 | Insulin Resistance | pirinixic acid | 2.90 | 16306350 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | pirinixic acid | 1.35 | 15474484 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12587719 12969438 19784758 16611625 16610002 19460945 11587558 19014921 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | pirinixic acid | 1.94 | 20007298 16377806 15890375 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009135 | Muscular Diseases | pirinixic acid | 4.16 | 16239165 | |
| MESH:D009203 | Myocardial Infarction | pirinixic acid | 2.29 | 19151258 | |
| MESH:D015428 | Myocardial Reperfusion Injury | pirinixic acid | 3.29 | 16411023 | |
| MESH:D009369 | Neoplasms | pirinixic acid | 2.12 | 17405874 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D009765 | Obesity | pirinixic acid | 1.89 | 20558911 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D015427 | Reperfusion Injury | pirinixic acid | 2.56 | 19058328 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:00604 | Glycosphingolipid biosynthesis - ganglio series |
| KEGG:01100 | Metabolic pathways |