Annotation Detail for PLCXD2
Basic Information Top
| Gene Symbol: | PLCXD2 ( FLJ31579 ) |
|---|---|
| Gene Full Name: | phosphatidylinositol-specific phospholipase C, X domain containing 2 |
| Band: | 3q13.2 |
| Quick Links | Entrez ID:257068; OMIM: NA; Uniprot ID:PLCX2_HUMAN; ENSEMBL ID: ENSG00000144824,ENSG00000240891; HGNC ID: 26462 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| No data |
| No data |
| Desease Name |
|---|
| NEUROLOGICAL |
| Cognitive performance |
| No data |
| No data |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of PLCXD2 mRNA | affects expression | 17562736 |
| D002117 | Calcitriol | Calcitriol results in increased expression of PLCXD2 mRNA | increases expression | 16002434 |
| C051890 | irinotecan | irinotecan analog results in increased expression of PLCXD2 mRNA | increases expression | 18927307 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 2.56 | 11237771 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 2.72 | 11237771 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D003110 | Colonic Neoplasms | irinotecan | 2.65 | 17725105 17287894 | |
| MESH:D015179 | Colorectal Neoplasms | irinotecan | 2.36 | 15273666 18259882 18509181 16391804 17454858 17159606 16303861 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 19420014 19739265 14550746 16081117 11739529 16227642 11461765 19370779 12540782 16109766 14725611 16393943 12153990 19164858 15619225 11421492 16781746 16485898 10774834 10915739 11743745 12594235 12705907 14986274 18071297 17562736 10663392 17906064 12392966 12958197 18713872 11834606 19416960 15968718 11529661 17522070 2444490 19085960 11287661 19923254 16177239 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 4.52 | 15138306 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 16611625 12587719 19784758 19014921 12969438 16610002 19460945 11587558 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D052016 | Mucositis | irinotecan | 5.75 | 17159606 | |
| MESH:D009362 | Neoplasm Metastasis | irinotecan | 3.31 | 18259882 | |
| MESH:D009447 | Neuroblastoma | irinotecan | 3.67 | 8761367 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D017599 | Neuroectodermal Tumors | irinotecan | 5.47 | 8761367 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 5.52 | 15572423 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 3.48 | 18247401 16289102 15754350 16644109 12479363 | |
| MESH:D013274 | Stomach Neoplasms | irinotecan | 2.36 | 15723263 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| No data |