AutismKB 2.0

Annotation Detail for ARHGAP30


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Basic Information Top
Gene Symbol:ARHGAP30 ( FLJ00267,FLJ44128 )
Gene Full Name: Rho GTPase activating protein 30
Band: 1q23.3
Quick LinksEntrez ID:257106; OMIM: NA; Uniprot ID:RHG30_HUMAN; ENSEMBL ID: ENSG00000186517; HGNC ID: 27414
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Signaling by Rho GTPases
No data
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Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D003474 Curcumin Curcumin results in decreased expression of ARHGAP30 mRNAdecreases expression 18421014
D003907 Dexamethasone Dexamethasone results in increased expression of ARHGAP30 mRNAincreases expression 17998272
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D019973 Alcohol-Related Disorders Curcumin 6.1517887948
MESH:D000544 Alzheimer Disease Curcumin 2.6915590663
MESH:D001169 Arthritis, Experimental Dexamethasone 3.8117659584
MESH:D001172 Arthritis, Rheumatoid Curcumin 2.8216807698
MESH:D050197 Atherosclerosis Curcumin 3.5818704882
MESH:D001327 Autoimmune Diseases Curcumin 5.2619761891
MESH:D002545 Brain Ischemia Curcumin 5.2216770732
MESH:D001932 Brain Neoplasms Curcumin 4.4417596214
MESH:D001943 Breast Neoplasms Curcumin 2.6918593918 16243823 19250217 18462866
MESH:D002277 Carcinoma Curcumin 4.2418593918
MESH:D002289 Carcinoma, Non-Small-Cell Lung Curcumin 3.1018414057
MESH:D002294 Carcinoma, Squamous Cell Curcumin 2.8618462866
MESH:D003092 Colitis Curcumin 4.9416782535 18200517 16804969
MESH:D003103 Coloboma Curcumin 5.1018809619
MESH:D003110 Colonic Neoplasms Curcumin 4.2519359593 16340194
MESH:D003110 Colonic Neoplasms Dexamethasone 4.2515824018
MESH:D016510 Corneal Neovascularization Curcumin 5.6618497527
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.3017728286
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 4.1612438553
MESH:D003924 Diabetes Mellitus, Type 2 Curcumin 2.7918403477
MESH:D003928 Diabetic Nephropathies Curcumin 4.4818204486
MESH:D003967 Diarrhea Dexamethasone 4.377237001
MESH:D004381 Duodenal Ulcer Curcumin 4.7217351913
MESH:D004485 Eczema Dexamethasone 5.1312438553
MESH:D004487 Edema Dexamethasone 3.9519703484
MESH:D005234 Fatty Liver Curcumin 4.2519297423
MESH:D005355 Fibrosis Curcumin 4.7518705752
MESH:D005770 Gastrointestinal Neoplasms Curcumin 5.4618462866
MESH:D005909 Glioblastoma Curcumin 3.7717596214
MESH:D006258 Head and Neck Neoplasms Curcumin 3.9718462866 18829502
MESH:D015417 Hereditary Sensory and Motor Neuropathy Curcumin 5.8017701891
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.207520565
MESH:D006937 Hypercholesterolemia Curcumin 4.6018704882
MESH:D006973 Hypertension Dexamethasone 3.0717042910
MESH:D007249 Inflammation Curcumin 6.1916956363 18403477 17151092
MESH:D007249 Inflammation Dexamethasone 6.198960868 11099482
MESH:D015212 Inflammatory Bowel Diseases Curcumin 3.3618200517 18596194
MESH:D007414 Intestinal Neoplasms Curcumin 4.7310783313
MESH:D007889 Leiomyoma Curcumin 5.1818555241
MESH:D007938 Leukemia Curcumin 3.4418462866
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell Curcumin 4.7616106398
MESH:D015458 Leukemia, T-Cell Curcumin 5.4416106398
MESH:D008106 Liver Cirrhosis, Experimental Curcumin 2.9618006644 18705752 17355460
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 2.9616718785
MESH:D008107 Liver Diseases Curcumin 2.7016956363
MESH:D008175 Lung Neoplasms Curcumin 2.9316243823 19359593 18462866
MESH:D008175 Lung Neoplasms Dexamethasone 2.9311195469 15824018
MESH:D008223 Lymphoma Curcumin 3.9318462866
MESH:D016399 Lymphoma, T-Cell Curcumin 5.4616173963
MESH:D008545 Melanoma Curcumin 2.4617885582 18462866
MESH:D008569 Memory Disorders Curcumin 4.8317263510
MESH:D009101 Multiple Myeloma Curcumin 8.7419372569
MESH:D009101 Multiple Myeloma Dexamethasone 8.7415744524 16118317 15867202
MESH:D009134 Muscular Atrophy, Spinal Curcumin 5.8017962980
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.789809623
MESH:D009361 Neoplasm Invasiveness Curcumin 5.0418495463
MESH:D009376 Neoplasms, Hormone-Dependent Curcumin 5.6012497104
MESH:D009423 Nervous System Neoplasms Curcumin 6.7018462866
MESH:D009765 Obesity Curcumin 2.8319297423
MESH:D010024 Osteoporosis Curcumin 3.7418719352
MESH:D010051 Ovarian Neoplasms Curcumin 2.9318462866 19020741
MESH:D010190 Pancreatic Neoplasms Curcumin 3.0619401701 17440100 19196508
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.7821297632
MESH:D011471 Prostatic Neoplasms Curcumin 3.6110851300 15129424 12497104 11398177 18156803 18226269 18769126
MESH:D011656 Pulmonary Emphysema Curcumin 5.0319168576
MESH:D012128 Respiratory Distress Syndrome, Adult Curcumin 11.3910666014 18379247
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 11.3911700416 18379247
MESH:D012509 Sarcoma Curcumin 4.6218462866
MESH:D018805 Sepsis Curcumin 4.5118389075
MESH:D013272 Stomach Diseases Dexamethasone 5.2115472012
MESH:D013276 Stomach Ulcer Curcumin 9.4119188055 16631530
MESH:D013276 Stomach Ulcer Dexamethasone 9.4115138204
MESH:D001749 Urinary Bladder Neoplasms Curcumin 3.0318593936
MESH:D014565 Urogenital Neoplasms Curcumin 6.1518462866
MESH:D014605 Uveitis Dexamethasone 5.891336536
Pathway ID Pathway Name
REACT:11044 Signaling by Rho GTPases
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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