Annotation Detail for TBC1D22A
Basic Information Top
| Gene Symbol: | TBC1D22A ( C22orf4,HSC79E021 ) |
|---|---|
| Gene Full Name: | TBC1 domain family, member 22A |
| Band: | 22q13.31 |
| Quick Links | Entrez ID:25771; OMIM: NA; Uniprot ID:TB22A_HUMAN; ENSEMBL ID: ENSG00000054611; HGNC ID: 1309 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Pathway Information| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of TBC1D22A mRNA | affects expression | 17562736 |
| D016604 | Aflatoxin B1 | Aflatoxin B1 affects the expression of TBC1D22A protein | affects expression | 20106945 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of TBC1D22A mRNA | decreases expression | 20106945 20064835 |
| D020122 | tert-Butylhydroperoxide | tert-Butylhydroperoxide results in decreased expression of TBC1D22A mRNA | decreases expression | 15336504 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.06 | 20464547 20127859 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.86 | 6695378 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.57 | 10982225 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.64 | 19183758 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.40 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.99 | 17474063 20146248 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 3.03 | 3084413 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Aflatoxin B1 | 3.03 | 21507988 12619106 12907637 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.13 | 20419170 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.79 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.67 | 11461765 15619225 12958197 12153990 19420014 19370779 16177239 12705907 15968718 16781746 12392966 16485898 14986274 14725611 16109766 17906064 10774834 10663392 17522070 14550746 19416960 12540782 11421492 11529661 19085960 2444490 11834606 19923254 16227642 11739529 18071297 11743745 16081117 10915739 18713872 19164858 16393943 12594235 11287661 17562736 19739265 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.82 | 19426721 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.08 | 16530937 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.40 | 16983495 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.83 | 20471113 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.02 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.40 | 12587719 15629191 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.70 | 12969438 19460945 16611625 11587558 12587719 19784758 16610002 19014921 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.63 | 17185352 16871587 | |
| MESH:D008113 | Liver Neoplasms | Aflatoxin B1 | 4.97 | 9163691 2125692 15890375 18177683 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 4.97 | 20195826 21137059 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Aflatoxin B1 | 2.96 | 8603461 | |
| MESH:D008175 | Lung Neoplasms | Aflatoxin B1 | 2.50 | 14755239 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 2.50 | 20464547 18569708 6695378 17053015 20869020 20064080 18520028 20135361 18816296 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.13 | 19513568 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.50 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.33 | 11141357 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.21 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.73 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.91 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 6.24 | 19755658 10029692 | |
| MESH:D012878 | Skin Neoplasms | tert-Butylhydroperoxide | 6.24 | 8532709 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 20155912 2093021 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.30 | 17053015 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.44 | 10982225 |
| No data |