AutismKB 2.0

Annotation Detail for CCDC19


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Basic Information Top
Gene Symbol:CCDC19 ( NESG1 )
Gene Full Name: coiled-coil domain containing 19
Band: 1q22
Quick LinksEntrez ID:25790; OMIM: 605152; Uniprot ID:CCD19_HUMAN; ENSEMBL ID: ENSG00000213085; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
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Chemical ID Chemical Name Interaction Interaction Action Publication
C472791 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid 3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid results in increased expression of CCDC19 mRNAincreases expression 16788091
D019324 beta-Naphthoflavone [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCDC19 mRNAaffects cotreatment|increases expression 18164116
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of CCDC19 mRNAaffects cotreatment|increases expression 18164116
D004054 Diethylstilbestrol Diethylstilbestrol results in decreased expression of CCDC19 mRNAdecreases expression 19371625
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma beta-Naphthoflavone 7.5719389873
MESH:D000236 Adenoma Diethylnitrosamine 7.5710737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.5317620307 19052882 19061943 16434500 18056438 17162532
MESH:D000686 Amyloidosis Diethylstilbestrol 4.9915469931
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2717474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.2717129689 15324884
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 3.3111831363 16830150 16935385 20512989 3084413 16540662 19539802 20935162 17138121 17428255 18393292 18494052 17761372 19107877 20214788 16698587 18506893 19383236 21159647 18978308 16779866 20101231 19822196 20524982 19052882 3581430 16288022 19335982 19171122 19394651 20727157 20084675 17173139 17162532 19208518 19519916 19701751 16807293 20007298 18785209 16569478 10737359 18210153 19418558 16328049 16878318 17978847 18788625 18971187 18665156 20432363 20514400 19919837 16681979 10672840 16502159 18056438 17055752 18691550
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 3.3116924424 15948411
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.1217174075 7505956 21159647 2727394
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0519052882
MESH:D003456 Cryptorchidism Diethylstilbestrol 5.0616002989 12952375
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2620387270
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 2.1419107877
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 5.3216402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 3.7016804899 15700306
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.8416302075
MESH:D005234 Fatty Liver Diethylnitrosamine 3.6120387270 21071580
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.8716534752 15751030 16611131 16002989 16513791
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 5.5816452187
MESH:D006965 Hyperplasia Diethylstilbestrol 5.0012960047 14722030
MESH:D007021 Hypospadias Diethylstilbestrol 5.1416002989
MESH:D007246 Infertility Diethylstilbestrol 4.8615036965
MESH:D007249 Inflammation Diethylnitrosamine 2.5518785209
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 3.8015003126 14681315 16762066
MESH:D007859 Learning Disorders Diethylstilbestrol 4.6217184923
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 3.0118522880 18407596 20032147 19638242 18665156
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1717034775
MESH:D008113 Liver Neoplasms beta-Naphthoflavone 8.3119389873 21295105
MESH:D008113 Liver Neoplasms Diethylnitrosamine 8.3112112319 2862719 18644402 20118626 18977376 20501860 19690152 18978307 16942905 19090486 19254457 19642983 20101389 18648771 19499222 2422723 20137499 19551842 19426721 21071580 19294768 21047994 18754104 19996281 20452335 19256749 19812893 20434301 12771043 19833225 19073162 9163691 19427195 19850985 21278145 15885732 15175105 20583210 19638242 20492335 10737359 21167192 20405173 19255062
MESH:D008113 Liver Neoplasms Diethylstilbestrol 8.3115890375 16712894
MESH:D008114 Liver Neoplasms, Experimental beta-Naphthoflavone 6.9018164116
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.903124819 19126423 17854601 18544905 19519916 18164116 18093689 18775883 16842330 18253720 18282651 18079962 21159647 19004024 17942915 17174075 18308698 16267830 9362446 2563599 19539802 19009564
MESH:D008175 Lung Neoplasms Diethylnitrosamine 1.7720970405 20512841 21163286 6695378
MESH:D008181 Lupus Nephritis Diethylstilbestrol 5.7815166399
MESH:D008223 Lymphoma Diethylstilbestrol 3.7515700306
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 6.2416002989
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.693581430 9029167
MESH:D009369 Neoplasms Diethylstilbestrol 2.9315313581
MESH:D009421 Nervous System Malformations Diethylstilbestrol 4.6411399458
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.6920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.8420387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5316540662
MESH:D010900 Pituitary Diseases Diethylstilbestrol 5.8914722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 5.2315687265 16977796
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.922563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 4.7417184923
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 3.5115046698 17136230 15846301
MESH:D013088 Spermatocele Diethylstilbestrol 5.4316709447 16002989
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.297505956
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 2.8916452187 16712894 17306315
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 4.4316175088
MESH:D014591 Uterine Diseases Diethylstilbestrol 5.8914652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 4.5716690809 15809267
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 5.0016513791 16002989
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018