AutismKB 2.0

Annotation Detail for TMEM184B


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Basic Information Top
Gene Symbol:TMEM184B ( C22orf5,DKFZp586A1024,DKFZp686F07174,DKFZp686N1150,FM08,HS5O6A )
Gene Full Name: transmembrane protein 184B
Band: 22q13.1
Quick LinksEntrez ID:25829; OMIM: NA; Uniprot ID:T184B_HUMAN; ENSEMBL ID: ENSG00000198792; HGNC ID: 1310
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of TMEM184B mRNAaffects expression 17562736
D005472 Fluorouracil TMEM184B protein affects the susceptibility to Fluorouracilaffects response to substance 16217747
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of TMEM184B mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of TMEM184B mRNAincreases expression 19270015
19482888
D014284 Triiodothyronine [Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of TMEM184B mRNAaffects cotreatment|increases expression 14761676
D013749 Tetrachlorodibenzodioxin [Triiodothyronine co-treated with Tetrachlorodibenzodioxin] results in increased expression of TMEM184B mRNAaffects cotreatment|increases expression 14761676
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 10.156195326
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 10.1515322242 14514962 11752688
MESH:D000230 Adenocarcinoma Fluorouracil 2.4917638652
MESH:D018248 Adenoma, Liver Cell Phenobarbital 11.9517620307
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.9516835633
MESH:D000740 Anemia Fluorouracil 9.8615504547 17963324 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.8611748828
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.4212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.4015340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9715746008
MESH:D001943 Breast Neoplasms Fluorouracil 2.0216110121 16557594 18357371 19217205 16595493 15136595 18608205
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.0220435547
MESH:D002276 Carcinoid Tumor Fluorouracil 5.2816051944
MESH:D002277 Carcinoma Fluorouracil 9.1617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 9.1616835633
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.823084413
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 4.8216332177 16799960 17045692 17971768 17088986 18930000
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 4.821701930 20935162 17173139 20007298 6705139
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1518695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5718986760 17066447 16757204 16280240
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.5418850075 16120746 18670907
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.744080065
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.4916835633
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.228697196 12621046 16354765 15340226 15668235
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2817287894 17016597 17172411 18772588 16340194 15001691 16510598 17169374 17018589 17725105
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.0016391804 18383874 18448328 16303861 18802399 15148649 20501625 17695437 15289873 14970324 18288408 16524972 17255274 18509181 16282729 17594712 17094418 17401013 18949393 17454858 17016601 16331619
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.3814669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2710048152 20055451 15322242
MESH:D007644 Darier Disease Fluorouracil 5.3316733453
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7317107852
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8319164858 12705907 16177239 11529661 16081117 18071297 15968718 14550746 12153990 11743745 10663392 19416960 17522070 11739529 15619225 14725611 19923254 17906064 11834606 16781746 17562736 16227642 2444490 10915739 16485898 11461765 16393943 19739265 12392966 11287661 10774834 12540782 19085960 19420014 14986274 18713872 11421492 12594235 16109766 19370779 12958197
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.8320420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 3.0211462148
MESH:D004421 Dystonia Phenobarbital 4.411851702
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.7412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.5115322242 16714409 18230668
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.3710568697 9294722
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.593659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.483922381 11558140
MESH:D004827 Epilepsy Phenobarbital 3.0420417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.876401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.747750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.563659116
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.5215173087 16481741 16785472 17638652 16337965
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.2711564622
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.9411858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.4320067830
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D005910 Glioma Fluorouracil 2.9816145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 5.2110696789
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.6115102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4910048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.7111000095
MESH:D006529 Hepatomegaly Phenobarbital 10.1016109766
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 10.1012621046 16120746 15340226
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.6616959395 18606429 16354765 15340226 8697196
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 2.0118850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 2.0112200463 12878042
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.7116580747
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D007680 Kidney Neoplasms Fluorouracil 3.6116985049
MESH:D008103 Liver Cirrhosis Phenobarbital 3.0721047994
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2512878042
MESH:D008107 Liver Diseases Acetaminophen 4.1719014921 11587558 19784758 16610002 19460945 16611625 12969438 12587719
MESH:D008107 Liver Diseases Phenobarbital 4.1719363144
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5816871587 17185352
MESH:D008113 Liver Neoplasms Fluorouracil 8.0916603448 15113037 17045692 18383874
MESH:D008113 Liver Neoplasms Phenobarbital 8.0921047994 8742319 15975961 19812893 19482888 19073162
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 8.0916984957
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 6.481399818 18308698 17172636 6150874 2563599
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.4812151625
MESH:D008175 Lung Neoplasms Fluorouracil 2.4315246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.4311884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.3315086387
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Fluorouracil 3.9016757204 18986760
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.3112213967
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 5.0217484760
MESH:D009369 Neoplasms Fluorouracil 2.7518600527 16928823 18239605
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.6514600291
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.6616436463
MESH:D010018 Osteomalacia Phenobarbital 4.9017016548
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 5.7016500647 19003803 16929163 15113037
MESH:D010190 Pancreatic Neoplasms Phenobarbital 5.7016965848
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.8612520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 4.0018163543
MESH:D011230 Precancerous Conditions Phenobarbital 3.952563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.7311399792 11118676 11222880 11896295
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3618626508 19082440
MESH:D019310 Pseudolymphoma Phenobarbital 5.1112752131
MESH:D012004 Rectal Neoplasms Fluorouracil 4.3415538739 18722050 18286688 16160472
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.2818990726
MESH:D012640 Seizures Phenobarbital 2.9211442880 3137016 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.366407741
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1816192470
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0016424979 18567086 19084572 19015929 17522103 16951190 15786421 18396642 17498489 17172411
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.5112697716
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.321399818
MESH:D014062 Tongue Neoplasms Fluorouracil 4.3416280240
MESH:D014581 Urticaria Acetaminophen 3.3810982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.2316803524
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 5.2112125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.8615886252
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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