Annotation Detail for MGAT4C
Basic Information
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| Gene Symbol: | MGAT4C ( GNTIVH,HGNT-IV-H ) |
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| Gene Full Name: | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative) |
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| Band: | 12q21.31-q21.32 |
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| Quick Links | Entrez ID:25834; OMIM: 607385; Uniprot ID:MGT4C_HUMAN; ENSEMBL ID: ENSG00000182050; HGNC ID: 30871 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Pathway ID | Pathway Name |
|---|
| hsa00510 | N-Glycan biosynthesis |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C068073 |
Am 580 |
Am 580 results in decreased expression of MGAT4C mRNA | decreases expression | 16982809
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in increased expression of MGAT4C mRNA | increases expression | 17879257
|
| D019259 |
Lamivudine |
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D019259 |
Lamivudine |
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D019259 |
Lamivudine |
[Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D019469 |
Indinavir |
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| C006253 |
pirinixic acid |
pirinixic acid results in decreased expression of MGAT4C mRNA | decreases expression | 17426115
|
| C089730 |
rosiglitazone |
rosiglitazone results in decreased expression of MGAT4C mRNA | decreases expression | 16982809
|
| D019258 |
Saquinavir |
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D015215 |
Zidovudine |
[Zidovudine co-treated with Lamivudine co-treated with Indinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D015215 |
Zidovudine |
[Zidovudine co-treated with Lamivudine co-treated with Saquinavir] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| D015215 |
Zidovudine |
[Zidovudine co-treated with Lamivudine] results in increased expression of MGAT4C mRNA | affects cotreatment|increases expression | 16931933
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000163 |
Acquired Immunodeficiency Syndrome |
|
Zidovudine |
5.13 | 9612607 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.38 | 18653653 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.03 | 20464547 20127859 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.78 | 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
3.82 | 16434500 |
| MESH:D000544 |
Alzheimer Disease |
|
rosiglitazone |
2.89 | 19621015 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.38 | 19183758 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.39 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.01 | 20146248 17474063 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.10 | 20419170 |
| MESH:D002386 |
Cataract |
|
Am 580 |
4.48 | 17460283 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.00 | 19176532 |
| MESH:D003092 |
Colitis |
|
Am 580 |
5.27 | 17035595 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.52 | 18249437 |
| MESH:D003920 |
Diabetes Mellitus |
|
rosiglitazone |
4.51 | 17446233 |
| MESH:D003924 |
Diabetes Mellitus, Type 2 |
|
rosiglitazone |
2.98 | 12642470 |
| MESH:D004362 |
Drug Toxicity |
|
Lamivudine |
9.38 | 15040536 |
| MESH:D004362 |
Drug Toxicity |
|
Zidovudine |
9.38 | 15040536 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
7.82 | 12083418 |
| MESH:D004487 |
Edema |
|
rosiglitazone |
7.82 | 12083418 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.06 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
14.75 | 20131406 19236843 |
| MESH:D005234 |
Fatty Liver |
|
rosiglitazone |
14.75 | 19196556 |
| MESH:D005234 |
Fatty Liver |
|
Zidovudine |
14.75 | 18299183 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.77 | 20471113 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.67 | 20558911 |
| MESH:D006402 |
Hematologic Diseases |
|
Zidovudine |
4.97 | 12579204 |
| MESH:D006509 |
Hepatitis B |
|
Lamivudine |
5.34 | 17703166 |
| MESH:D019694 |
Hepatitis B, Chronic |
|
Lamivudine |
5.34 | 15274664 16476009 15309715 15631357 12044531 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.30 | 19176532 16221962 19772884 18467677 |
| MESH:D015658 |
HIV Infections |
|
Indinavir |
16.46 | 11363243 15388451 11141242 |
| MESH:D015658 |
HIV Infections |
|
Lamivudine |
16.46 | 17530837 11141242 9296927 20032539 |
| MESH:D015658 |
HIV Infections |
|
Saquinavir |
16.46 | 11141242 15388451 |
| MESH:D015658 |
HIV Infections |
|
Zidovudine |
16.46 | 20032539 11363243 11698656 17358032 11141242 |
| MESH:D006930 |
Hyperalgesia |
|
rosiglitazone |
4.11 | 12083418 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.41 | 20558911 |
| MESH:D007249 |
Inflammation |
|
rosiglitazone |
3.23 | 12083418 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
8.00 | 16306350 |
| MESH:D007333 |
Insulin Resistance |
|
rosiglitazone |
8.00 | 16306350 |
| MESH:D007680 |
Kidney Neoplasms |
|
Zidovudine |
3.98 | 12579204 |
| MESH:D015459 |
Leukemia-Lymphoma, Adult T-Cell |
|
Zidovudine |
4.65 | 20370541 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
2.66 | 15474484 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
rosiglitazone |
2.66 | 17347453 15980055 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.62 | 20195826 21137059 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.62 | 20007298 15890375 16377806 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
2.70 | 18569708 20464547 17053015 18816296 18520028 20869020 20135361 6695378 20064080 |
| MESH:D008175 |
Lung Neoplasms |
|
Zidovudine |
2.70 | 18800350 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
rosiglitazone |
3.53 | 16827153 |
| MESH:D024821 |
Metabolic Syndrome X |
|
rosiglitazone |
4.58 | 17261469 |
| MESH:D048629 |
Micronuclei, Chromosome-Defective |
|
Zidovudine |
6.21 | 17358032 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.37 | 16381670 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.81 | 16239165 |
| MESH:D009164 |
Mycobacterium Infections |
|
Indinavir |
5.79 | 21442799 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.22 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.13 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
5.17 | 11141357 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.17 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.86 | 20558911 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.93 | 17292933 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.49 | 19058328 |
| MESH:D012206 |
Rhabdomyolysis |
|
Lamivudine |
5.87 | 9296927 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.46 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
2.64 | 2093021 20155912 |
| MESH:D013274 |
Stomach Neoplasms |
|
Zidovudine |
2.64 | 17696246 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.25 | 17053015 |
| MESH:D014625 |
Vaginal Neoplasms |
|
Zidovudine |
5.06 | 12579204 |
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