AutismKB 2.0

Annotation Detail for RAB26


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Basic Information Top
Gene Symbol:RAB26 ( V46133 )
Gene Full Name: RAB26, member RAS oncogene family
Band: 16p13.3
Quick LinksEntrez ID:25837; OMIM: 605455; Uniprot ID:RAB26_HUMAN; ENSEMBL ID: ENSG00000167964; HGNC ID: 14259
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of RAB26 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of RAB26 mRNAaffects expression 16483693
D016572 Cyclosporine Cyclosporine results in decreased expression of RAB26 mRNAdecreases expression 20106945
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of RAB26 mRNAaffects cotreatment|increases expression 19619570
D004958 Estradiol Estradiol results in increased expression of RAB26 mRNAincreases expression 19619570
D000431 Ethanol Ethanol results in decreased expression of RAB26 mRNAdecreases expression 17920746
D005419 Flavonoids Flavonoids results in increased expression of RAB26 mRNAincreases expression 18035473
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of RAB26 mRNAaffects cotreatment|increases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of RAB26 mRNAincreases expression 19619570
D014810 Vitamin E Vitamin E results in decreased expression of RAB26 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Ethanol 9.6218926900 17676605
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 9.6211752688 15322242 14514962
MESH:D000138 Acidosis Ammonium Chloride 11.6218287403
MESH:D000138 Acidosis Ethanol 11.6211192467
MESH:D000230 Adenocarcinoma Estradiol 2.1411473722
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.7116835633
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 5.7015451040 15451039
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D000853 Anophthalmos Ethanol 5.1315513904
MESH:D001008 Anxiety Disorders Ethanol 4.2011141031
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Estradiol 1.9118497071 17289903 19861407 16675129 17018787 12948864 17261762 14630087
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9120435547
MESH:D002056 Burns Ethanol 4.9616374292
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.8016111702
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.2416050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 4.8521507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Estradiol 4.8516924424
MESH:D006528 Carcinoma, Hepatocellular Ethanol 4.8518788625 15763234 15289165
MESH:D006332 Cardiomegaly Ethanol 7.2519332462
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 7.2518850075 18670907 16120746
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 7.1112371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 7.1118566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3816835633
MESH:D002779 Cholestasis Cyclosporine 3.0919486331
MESH:D002971 Cleft Lip Ethanol 3.6915513904
MESH:D002972 Cleft Palate Ethanol 6.2415513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 6.2415668235 15340226 12621046 8697196 16354765
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2717141729 14669216
MESH:D019465 Craniofacial Abnormalities Ethanol 3.9515451039 15451040 19302082 11198716 11873399 10194807 15513904
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 3.9520055451 10048152 15322242
MESH:D019465 Craniofacial Abnormalities Vitamin E 3.9519769572
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.6319279558
MESH:D056486 Drug-Induced Liver Injury Ethanol 4.1311566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 4.1320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:C538011 Eales disease Vitamin E 5.089068938
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2818230668 15322242 16714409
MESH:D016889 Endometrial Neoplasms Estradiol 3.1319148513 18566989 11473722
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.259294722 10568697
MESH:D004938 Esophageal Neoplasms Ethanol 2.8016704527
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Cyclosporine 8.7319224547
MESH:D005234 Fatty Liver Ethanol 8.7318620774 19236843 16409862
MESH:D005235 Fatty Liver, Alcoholic Ethanol 6.0417920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 5.6416946407 15513904 10194807 15451040
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Cyclosporine 9.5212639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.5220067830
MESH:D005756 Gastritis Ethanol 5.0715046732
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.568708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.9510048152 11294989
MESH:D006330 Heart Defects, Congenital Vitamin E 6.9516080930
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7615720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2012621046 16120746 15340226
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7716863852 16490937
MESH:D006558 Herpes Genitalis Estradiol 5.4115709030
MESH:D019584 Hot Flashes Estradiol 11.3417088409
MESH:D019584 Hot Flashes Vitamin E 11.3414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.4216354765 15340226 18606429 8697196 16959395
MESH:D006930 Hyperalgesia Ethanol 3.9118783367
MESH:D006973 Hypertension Cyclosporine 5.2110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.2118670907 18850075
MESH:D007249 Inflammation Flavonoids 5.3717296493
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.3712200463 12878042
MESH:D007251 Influenza, Human Vitamin E 4.5916624496
MESH:D007333 Insulin Resistance Estradiol 3.1116393666 16627594
MESH:D007569 Jaw Abnormalities Ethanol 10.9415513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 10.9416580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.8215604871
MESH:D007674 Kidney Diseases Cyclosporine 10.8018776723 8314463 10903974
MESH:D007674 Kidney Diseases Estradiol 10.8015618244
MESH:D007674 Kidney Diseases Vitamin E 10.8012488133
MESH:D007680 Kidney Neoplasms Cyclosporine 7.9512371664
MESH:D007680 Kidney Neoplasms Estradiol 7.9515610895
MESH:D007859 Learning Disorders Ethanol 4.5215451040
MESH:D017880 Limb Deformities, Congenital Ethanol 3.9817676605
MESH:D008103 Liver Cirrhosis Ethanol 3.4915289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 5.4318295389
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.1714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 5.1718166357
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.1712878042
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 5.1716169303
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.9617347304 17207112
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.7015890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.7016984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.288603461
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2812151625
MESH:D008171 Lung Diseases Vitamin E 3.3316863852
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.5314755239
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.5319555203 11884234
MESH:D008175 Lung Neoplasms Vitamin E 3.5311062179
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.7011807958 16891317 17203775 11408345
MESH:D020149 Manganese Poisoning Estradiol 4.8619453300
MESH:D008569 Memory Disorders Ethanol 4.4715451040 18411066
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1616801185
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.4616810080
MESH:D009389 Neovascularization, Pathologic Estradiol 4.0717289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.8217954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.5019348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 10.4216427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.4214600291
MESH:D010051 Ovarian Neoplasms Estradiol 2.2819401270
MESH:D010190 Pancreatic Neoplasms Ethanol 3.0412384795
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.4412371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311118676 11896295 11399792 11222880
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.1320887781
MESH:D011471 Prostatic Neoplasms Estradiol 3.1816740699
MESH:D011471 Prostatic Neoplasms Vitamin E 3.1815084515
MESH:D011565 Psoriasis Cyclosporine 2.3016882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012640 Seizures Ethanol 3.329754883
MESH:D012871 Skin Diseases Vitamin E 2.4918709164
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1416192470
MESH:D013274 Stomach Neoplasms Ethanol 2.3118456281
MESH:D013276 Stomach Ulcer Ethanol 3.7716755016 11906479 17189318 17918041 9211565 9562338
MESH:D020521 Stroke Vitamin E 3.7116517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 4.489754883
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2812697716
MESH:D013978 Tibial Fractures Estradiol 5.0619048282
MESH:D014605 Uveitis Cyclosporine 4.361336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.8217120751
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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