AutismKB 2.0

Annotation Detail for ANAPC13


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Basic Information Top
Gene Symbol:ANAPC13 ( APC13,DKFZp566D193,SWM1 )
Gene Full Name: anaphase promoting complex subunit 13
Band: 3q22.2
Quick LinksEntrez ID:25847; OMIM: NA; Uniprot ID:APC13_HUMAN; ENSEMBL ID: ENSG00000129055; HGNC ID: 24540
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa04914Progesterone-mediated oocyte maturation
hsa04120Ubiquitin mediated proteolysis
hsa04110Cell cycle
hsa04114Oocyte meiosis
No data
No data
No data
No data
Related Diseases/Disorders Top
No data
No data
Desease Name
height
DEVELOPMENTAL
Desease Name
Height
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of ANAPC13 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of ANAPC13 mRNAaffects expression 17562736
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 3.003712494
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 6.091440618 11289319
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 2.983581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.983084413
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.867296757
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 3.087505956
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 3.5119486331 9022650
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.558970840 2524372 11298694 8156756 11906362 18759878 12868966 14531868
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.102952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 4.089022650 7440962 6482804 1440618 11289319 16192314 8291058 9328219 18692083 18289764 9653073 6679447 18648102
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0816485898 16109766 14550746 11421492 10774834 12594235 12153990 16177239 11529661 16081117 11739529 19164858 12540782 19923254 11743745 19420014 12392966 16227642 16393943 15619225 17562736 11834606 19370779 17906064 10663392 19085960 19739265 14986274 12705907 12958197 16781746 15968718 19416960 17522070 14725611 2444490 11287661 18071297 10915739 11461765 18713872
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 2.193581430
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 6.096705139
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.647505956
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.196705139
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.7015034207
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 6.099022650 8074119
MESH:D007674 Kidney Diseases Acetaminophen 2.4412587719 15629191
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.406582329
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.479327722 15034207
MESH:D008107 Liver Diseases Acetaminophen 1.7112969438 16610002 16611625 12587719 19784758 19014921 19460945 11587558
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7417185352 16871587
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.803712494 1399818 598648 6587162
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.623581430
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.216679447
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.926482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 6.093988306
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.247296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.546228378
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.743692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.266582329 1399818 7505956 6587162 3712494
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.428074119
MESH:D014581 Urticaria Acetaminophen 3.5810982225
Pathway ID Pathway Name
KEGG:04110 Cell cycle
KEGG:04114 Oocyte meiosis
KEGG:04914 Progesterone-mediated oocyte maturation
KEGG:04120 Ubiquitin mediated proteolysis
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  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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