AutismKB 2.0

Annotation Detail for ALS2CL


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Basic Information Top
Gene Symbol:ALS2CL ( DKFZp686P238,MGC129698,RN49018 )
Gene Full Name: ALS2 C-terminal like
Band: 3p21.31
Quick LinksEntrez ID:259173; OMIM: 612402; Uniprot ID:AL2CL_HUMAN; ENSEMBL ID: ENSG00000178038; HGNC ID: 20605
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2134Amyotrophic lateral sclerosis
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C006253 pirinixic acid pirinixic acid results in increased expression of ALS2CL mRNAincreases expression 18445702
18301758
D012643 Selenium Selenium results in increased expression of ALS2CL mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.7218653653
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.3716434500
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.7019483382
MESH:D002779 Cholestasis pirinixic acid 3.1919176532
MESH:D003092 Colitis Selenium 4.5417936198
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.6118249437
MESH:D056486 Drug-Induced Liver Injury Selenium 2.2715131321
MESH:D004487 Edema pirinixic acid 3.0212083418
MESH:D005234 Fatty Liver pirinixic acid 3.3119236843 20131406
MESH:D006333 Heart Failure pirinixic acid 7.8620558911
MESH:D006333 Heart Failure Selenium 7.8617162251
MESH:D006529 Hepatomegaly pirinixic acid 3.7616221962 19772884 18467677 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.6920558911
MESH:D007251 Influenza, Human Selenium 5.2716624496
MESH:D007333 Insulin Resistance pirinixic acid 2.9316306350
MESH:D007676 Kidney Failure, Chronic Selenium 4.4416518626
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9515890375 16377806 20007298
MESH:D008325 Mammary Neoplasms, Experimental Selenium 3.0515318939
MESH:D008654 Mesothelioma Selenium 2.9415107826
MESH:D009135 Muscular Diseases pirinixic acid 4.2716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.3019151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.3316411023
MESH:D009369 Neoplasms pirinixic acid 2.1417405874
MESH:D009765 Obesity pirinixic acid 1.9020558911
MESH:D010954 Plasmacytoma Selenium 5.9615087411
MESH:D015427 Reperfusion Injury pirinixic acid 2.5819058328
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA134949717
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    No data
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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