Annotation Detail for COBRA1
Basic Information Top
| Gene Symbol: | COBRA1 ( DKFZp586B0519,KIAA1182,NELF-B,NELFB ) |
|---|---|
| Gene Full Name: | cofactor of BRCA1 |
| Band: | 9q34 |
| Quick Links | Entrez ID:25920; OMIM: 611180; Uniprot ID:NELFB_HUMAN; ENSEMBL ID: ENSG00000188986; HGNC ID: |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| Elongation arrest and recovery | |
| Pausing and recovery of elongation | |
| Transcription | |
| Gene Expression | |
| HIV Infection |
| No data |
| No data |
| Pathway ID | Pathway Name |
|---|---|
| 500949 | RNA Polymerase II Pre-transcription Events |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | Acetaminophen affects the expression of COBRA1 mRNA | affects expression | 17562736 |
| C004925 | methylmercuric chloride | methylmercuric chloride results in decreased expression of COBRA1 mRNA | decreases expression | 17961207 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | methylmercuric chloride | 5.61 | 6734493 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.91 | 10982225 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.83 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 16177239 16485898 12392966 11739529 16081117 11743745 15619225 18713872 10774834 16393943 15968718 19420014 19085960 19164858 16109766 12594235 11421492 17562736 10915739 11529661 19739265 19370779 16227642 2444490 14986274 19923254 12540782 12705907 11461765 11287661 12958197 12153990 16781746 14725611 19416960 17906064 18071297 10663392 11834606 17522070 14550746 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 5.17 | 19426721 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.74 | 16983495 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.11 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.44 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 19460945 16610002 19784758 16611625 12969438 11587558 19014921 12587719 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.74 | 17185352 16871587 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.33 | 19513568 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.31 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.82 | 16870215 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.58 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| REACT:1892 | Elongation arrest and recovery |
| REACT:71 | Gene Expression |
| REACT:6185 | HIV Infection |
| REACT:769 | Pausing and recovery of elongation |
| REACT:1788 | Transcription |
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