AutismKB 2.0

Annotation Detail for TMEM87A


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Basic Information Top
Gene Symbol:TMEM87A ( DKFZp564G2022 )
Gene Full Name: transmembrane protein 87A
Band: 15q15.1
Quick LinksEntrez ID:25963; OMIM: NA; Uniprot ID:TM87A_HUMAN; ENSEMBL ID: ENSG00000103978; HGNC ID: 24522
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of TMEM87A mRNAdecreases expression 18648102
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of TMEM87A mRNAdecreases expression 19150397
D016572 Cyclosporine Cyclosporine results in increased expression of TMEM87A mRNAincreases expression 20106945
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 2.983712494
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.8911289319 1440618
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 1.783581430 7296757
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 2.847296757
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 12.887505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 12.8820889678
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.8812371664
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.989022650 19486331
MESH:D002779 Cholestasis Cyclosporine 8.9819486331
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 3.448156756 8970840 14531868 18759878 11906362 12868966 2524372 11298694
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 4.022952479 3621924
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 2.059653073 9328219 18289764 9022650 18692083 1440618 8291058 6679447 7440962 16192314 6482804 18648102 11289319
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 4.683581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6820426865
MESH:D005234 Fatty Liver Cyclosporine 3.3419224547
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.896705139
MESH:D005355 Fibrosis Cyclosporine 3.7912639820 12168785
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.968708960
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.577505956
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 5.1615720958
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 4.106705139
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.5915034207
MESH:D006973 Hypertension Cyclosporine 2.2310903974
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.899022650 8074119
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 5.3115604871
MESH:D007674 Kidney Diseases Cyclosporine 2.568314463 10903974 18776723
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 8.586582329
MESH:D007680 Kidney Neoplasms Cyclosporine 8.5812371664
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.449327722 15034207
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 2.783712494 1399818 6587162 598648
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.6516801185
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 2.613581430
MESH:D009402 Nephrosis, Lipoid Cyclosporine 5.3117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.7019348381 18481113
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 3.186679447
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.874026338 6482804
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.893988306
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 4.137296757
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 5.346228378
MESH:D011230 Precancerous Conditions Cyclosporine 3.6412371664
MESH:D011565 Psoriasis Cyclosporine 2.3416882103
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.703692021
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 3.223712494 6587162 7505956 6582329 1399818
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.418074119
MESH:D014605 Uveitis Cyclosporine 4.851336536
MESH:D014985 Xerophthalmia Cyclosporine 5.3117120751
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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