AutismKB 2.0

Annotation Detail for DNAH1


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Basic Information Top
Gene Symbol:DNAH1 ( DNAHC1,HDHC7,HL-11,HL11,XLHSRF-1 )
Gene Full Name: dynein, axonemal, heavy chain 1
Band: 3p21.1
Quick LinksEntrez ID:25981; OMIM: 603332; Uniprot ID:DYH1_HUMAN; ENSEMBL ID: ENSG00000114841; HGNC ID: 2940
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
Pathway IDPathway Name
hsa05016Huntington's disease
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of DNAH1 mRNAaffects expression 21346803
D000643 Ammonium Chloride Ammonium Chloride affects the expression of DNAH1 mRNAaffects expression 16483693
D008628 Mercury Mercury results in decreased expression of DNAH1 mRNAdecreases expression 16823088
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.3018287403
MESH:D001321 Autistic Disorder Mercury 2.7617497416
MESH:D001327 Autoimmune Diseases Mercury 5.5216634805
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7916705839
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.5710334427
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.066135515
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.6718551238
MESH:D017449 Dermatitis, Allergic Contact Mercury 4.4316823706
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0618551238 21346803
MESH:D007674 Kidney Diseases Mercury 3.7817934191
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.3616705839
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 2.287678174
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.792876784 2876786 6135515
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.6018551238 7678174
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.8816049721
MESH:D012640 Seizures 2,6-dinitrotoluene 2.8218551238
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.4216049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 5.0610091137
Pathway ID Pathway Name
KEGG:05016 Huntington's disease
Pharmacogenomics Knowledge Base Top
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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