AutismKB 2.0

Annotation Detail for ABP1


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Basic Information Top
Gene Symbol:ABP1 ( ABP,AOC1,DAO,DAO1,KAO )
Gene Full Name: amiloride binding protein 1 (amine oxidase (copper-containing))
Band: 7q34-q36
Quick LinksEntrez ID:26; OMIM: 104610; Uniprot ID:ABP1_HUMAN; ENSEMBL ID: ENSG00000002726; HGNC ID:
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-6181histamine degradation
Pathway IDPathway Name
hsa00380Tryptophan metabolism
hsa00330Arginine and proline metabolism
hsa00340Histidine metabolism
No data
No data
Pathway IDPathway Name
P02766Phenylethylamine degradation
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
2171Celiac disease
Desease Name
ulcerative colitis
PHARMACOGENOMIC
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of ABP1 proteinaffects expression 20106945
D000584 Amiloride Amiloride binds to ABP1 proteinaffects binding 2217167
D000584 Amiloride Amiloride inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
D000584 Amiloride Amiloride results in decreased activity of ABP1 proteindecreases activity 8144586
D000499 Allylamine Allylamine affects the expression of ABP1 mRNAaffects expression 15910882
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ABP1 mRNAaffects expression 16483693
C013407 benzamil benzamil binds to ABP1 proteinaffects binding 2217167
C018021 cobaltous chloride cobaltous chloride binds to ABP1 proteinaffects binding 16842785
C029892 cupric chloride cupric chloride results in increased activity of ABP1 proteinincreases activity 16842785
D003513 Cycloheximide Cycloheximide inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D003513 Cycloheximide Cycloheximide inhibits the reaction [Terbutaline results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D016572 Cyclosporine Cyclosporine results in decreased expression of ABP1 mRNAdecreases expression 20106945
D003609 Dactinomycin Dactinomycin inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D003609 Dactinomycin Dactinomycin inhibits the reaction [Terbutaline results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
C021006 diaminobutene diaminobutene results in decreased activity of ABP1 proteindecreases activity 7492592
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ABP1 mRNAincreases expression 19638242
D004054 Diethylstilbestrol Diethylstilbestrol results in increased expression of ABP1 mRNAincreases expression 15289156
D004837 Epinephrine Cycloheximide inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D004837 Epinephrine Dactinomycin inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D004837 Epinephrine Epinephrine results in increased activity of ABP1 proteinincreases activity 2860926
D004837 Epinephrine Timolol inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D004958 Estradiol Estradiol results in increased expression of ABP1 mRNAincreases expression 15289156
C039614 ethylisopropylamiloride ethylisopropylamiloride binds to ABP1 proteinaffects binding 2217167
C039614 ethylisopropylamiloride ethylisopropylamiloride inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
C039614 ethylisopropylamiloride ethylisopropylamiloride results in decreased activity of ABP1 proteindecreases activity 8144586
D005576 Forskolin Forskolin results in increased activity of ABP1 proteinincreases activity 2860926
D019833 Genistein Genistein results in increased expression of ABP1 mRNAincreases expression 15289156
C004380 H 35-25 H 35-25 inhibits the reaction [Isoproterenol results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
C010176 halofuginone halofuginone results in increased expression of ABP1 mRNAincreases expression 17180598
D006830 Hydralazine [Hydralazine co-treated with Valproic Acid] results in increased expression of ABP1 mRNAaffects cotreatment|increases expression 17183730
D007545 Isoproterenol H 35-25 inhibits the reaction [Isoproterenol results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D007545 Isoproterenol Isoproterenol results in increased activity of ABP1 proteinincreases activity 2860926
D008727 Methotrexate ABP1 protein affects the susceptibility to Methotrexateaffects response to substance 16217747
C029938 nickel sulfate nickel sulfate results in increased expression of ABP1 mRNAincreases expression 16780908
C047088 phenylamil phenylamil binds to ABP1 proteinaffects binding 2217167
C047088 phenylamil phenylamil inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
C047088 phenylamil phenylamil results in decreased activity of ABP1 proteindecreases activity 8144586
C047088 phenylamil phenylamil binds to ABP1 proteinaffects binding 8144586
C004479 pimagedine pimagedine results in decreased activity of ABP1 proteindecreases activity 11445272
C004479 pimagedine pimagedine inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
C004479 pimagedine pimagedine results in decreased activity of ABP1 proteindecreases activity 8144586
D011700 Putrescine ABP1 protein results in increased degradation of Putrescineincreases degradation 8144586
D011700 Putrescine Amiloride inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
D011700 Putrescine ethylisopropylamiloride inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
D011700 Putrescine phenylamil inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
D011700 Putrescine pimagedine inhibits the reaction [ABP1 protein results in increased degradation of Putrescine]decreases reaction|increases degradation 8144586
D011700 Putrescine ABP1 protein results in increased degradation of Putrescineincreases degradation 8144586
C009277 sodium arsenate sodium arsenate results in decreased expression of ABP1 mRNAdecreases expression 12727804
C017947 sodium arsenite sodium arsenite results in decreased expression of ABP1 mRNAdecreases expression 12727804
D013726 Terbutaline Cycloheximide inhibits the reaction [Terbutaline results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D013726 Terbutaline Dactinomycin inhibits the reaction [Terbutaline results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D013726 Terbutaline Terbutaline results in increased activity of ABP1 proteinincreases activity 2860926
D013806 Theophylline Theophylline results in increased activity of ABP1 proteinincreases activity 2860926
D013999 Timolol Timolol inhibits the reaction [Epinephrine results in increased activity of ABP1 protein]decreases reaction|increases activity 2860926
D014635 Valproic Acid [Hydralazine co-treated with Valproic Acid] results in increased expression of ABP1 mRNAaffects cotreatment|increases expression 17183730
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Methotrexate 12.7012039119
MESH:D000014 Abnormalities, Drug-Induced Terbutaline 12.7014610225
MESH:D000014 Abnormalities, Drug-Induced Valproic Acid 12.708875741
MESH:D000015 Abnormalities, Multiple Valproic Acid 3.6419490988
MESH:D000138 Acidosis Ammonium Chloride 3.2318287403
MESH:D055371 Acute Lung Injury nickel sulfate 4.0119131640 16100012 11954676 12718980
MESH:D000230 Adenocarcinoma Estradiol 4.1711473722
MESH:D000230 Adenocarcinoma Genistein 4.1711473722
MESH:D000236 Adenoma Diethylnitrosamine 2.666695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 3.5817620307 19061943 17162532 19052882 18056438 16434500
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5717306315 16712894
MESH:D000550 Amblyopia Valproic Acid 4.9017688650
MESH:D000686 Amyloidosis Diethylstilbestrol 10.5715469931
MESH:D000686 Amyloidosis Terbutaline 10.577986221
MESH:D001008 Anxiety Disorders Valproic Acid 3.3217497229
MESH:D001172 Arthritis, Rheumatoid Methotrexate 3.0217286800
MESH:D001249 Asthma Theophylline 3.769701106 12113382
MESH:D001321 Autistic Disorder Terbutaline 2.5916417856 17400887
MESH:D001321 Autistic Disorder Valproic Acid 2.5918985861 18316065 18396377 17157402 19232924 16609825 19460635 18775368 18940202 18177632 18558336 17688650 15238991 20603192 17507914
MESH:D001714 Bipolar Disorder Valproic Acid 2.9117594078 20046352
MESH:D001848 Bone Diseases, Developmental Valproic Acid 3.198888407
MESH:D019046 Bone Marrow Neoplasms Dactinomycin 5.2114601052
MESH:D001919 Bradycardia Isoproterenol 4.866740701
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.2517474063
MESH:D001943 Breast Neoplasms Diethylstilbestrol 2.2517129689 15324884
MESH:D001943 Breast Neoplasms Estradiol 2.2517289903 14630087 16675129 17261762 12948864 18497071 17018787 19861407
MESH:D001943 Breast Neoplasms Genistein 2.2516873071 16541309 17200150
MESH:D001943 Breast Neoplasms Methotrexate 2.2516978400
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.1416111702
MESH:D019559 Capillary Leak Syndrome Terbutaline 5.539428835 11713377
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 10.6221507988 12907637 12619106
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 10.6220524982 19418558 17138121 16681979 17978847 16569478 18393292 20514400 18506893 17055752 16502159 18056438 19208518 20214788 19052882 10737359 20007298 19919837 11831363 18971187 16779866 18788625 3084413 18665156 17173139 16878318 17761372 10672840 19701751 20727157 21159647 18691550 16328049 16935385 19539802 20432363 16288022 20935162 19171122 17162532 18210153 18785209 19822196 19107877 19383236 16807293 19519916 20084675 3581430 19335982 19394651 18494052 18978308 16698587 16540662 16830150 17428255 20512989 20101231
MESH:D006528 Carcinoma, Hepatocellular Diethylstilbestrol 10.6216924424 15948411
MESH:D006528 Carcinoma, Hepatocellular Estradiol 10.6216924424
MESH:D006528 Carcinoma, Hepatocellular Genistein 10.6216924424
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 10.6215276417 17306315 16507464
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 2.2918572023
MESH:D002295 Carcinoma, Transitional Cell Amiloride 4.8014644129
MESH:D006332 Cardiomegaly Isoproterenol 3.997544033 11179087
MESH:D009202 Cardiomyopathies pimagedine 4.6616612575
MESH:D002318 Cardiovascular Diseases Genistein 3.0816332659
MESH:D002386 Cataract pimagedine 4.5917936468 15003327
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 14.1812371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 14.1817174075 2727394 7505956 21159647
MESH:D002471 Cell Transformation, Neoplastic Estradiol 14.1818566989
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 14.1820056578 19524636
MESH:D002637 Chest Pain Theophylline 5.5415238202
MESH:D002659 Child Development Disorders, Pervasive Valproic Acid 2.5920734317
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 3.4119052882
MESH:D002779 Cholestasis Cyclosporine 2.6819486331
MESH:D003092 Colitis Amiloride 4.7912065299
MESH:D003110 Colonic Neoplasms Genistein 2.2317182828
MESH:D003371 Cough Terbutaline 5.2319679606
MESH:D019465 Craniofacial Abnormalities Methotrexate 3.8512039119 9562676
MESH:D019465 Craniofacial Abnormalities sodium arsenate 3.8510525206
MESH:D019465 Craniofacial Abnormalities Valproic Acid 3.858888407 17688650 16575769
MESH:D003456 Cryptorchidism Diethylstilbestrol 4.2512952375 16002989
MESH:D003550 Cystic Fibrosis Methotrexate 3.9619747007
MESH:D017449 Dermatitis, Allergic Contact cobaltous chloride 6.5615059100 16823706 11298694
MESH:D017449 Dermatitis, Allergic Contact nickel sulfate 6.5611298694 16823706 16780908
MESH:D003882 Dermatomyositis Methotrexate 4.8120191521
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2320387270
MESH:D003924 Diabetes Mellitus, Type 2 Genistein 4.2316647724
MESH:D003928 Diabetic Nephropathies Estradiol 3.1419279558
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 5.8019107877
MESH:D056486 Drug-Induced Liver Injury sodium arsenate 5.8018186108
MESH:D056486 Drug-Induced Liver Injury Valproic Acid 5.801733752 19641884
MESH:D004421 Dystonia Valproic Acid 3.751851702
MESH:D004714 Endometrial Hyperplasia Diethylstilbestrol 10.8116402032
MESH:D004714 Endometrial Hyperplasia Genistein 10.8116402032
MESH:D016889 Endometrial Neoplasms Diethylstilbestrol 11.2916804899 15700306
MESH:D016889 Endometrial Neoplasms Estradiol 11.2918566989 11473722 19148513
MESH:D016889 Endometrial Neoplasms Genistein 11.2911473722
MESH:D004831 Epilepsies, Myoclonic Valproic Acid 3.843659116 17275665
MESH:D004828 Epilepsies, Partial Valproic Acid 3.593922381 16628512
MESH:D004827 Epilepsy Epinephrine 6.74821787
MESH:D004827 Epilepsy Valproic Acid 6.7418234410 20417680
MESH:D004832 Epilepsy, Absence Valproic Acid 3.326426943 6254150 7562514
MESH:D017029 Epilepsy, Complex Partial Valproic Acid 3.987750514
MESH:D004830 Epilepsy, Tonic-Clonic Valproic Acid 3.743659116
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 4.7916302075
MESH:D005234 Fatty Liver Cyclosporine 11.4519224547
MESH:D005234 Fatty Liver Diethylnitrosamine 11.4520387270 21071580
MESH:D005234 Fatty Liver Valproic Acid 11.4519224547 14986274
MESH:D052776 Female Urogenital Diseases Diethylstilbestrol 3.4616002989 16513791 15751030 16611131 16534752
MESH:D005315 Fetal Diseases Valproic Acid 4.5616575769
MESH:D005317 Fetal Growth Retardation Valproic Acid 3.8218558336 8888407
MESH:D005355 Fibrosis Cyclosporine 8.1912639820 12168785
MESH:D005355 Fibrosis Terbutaline 8.1915467267
MESH:D005833 Genital Neoplasms, Female Diethylstilbestrol 11.7316452187
MESH:D005833 Genital Neoplasms, Female sodium arsenite 11.7316452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 3.898708960
MESH:D005909 Glioblastoma Genistein 3.0516598420
MESH:D018149 Glucose Intolerance sodium arsenate 4.7819446573
MESH:D006086 Graft vs Host Disease Methotrexate 4.8316518429
MESH:D006130 Growth Disorders Amiloride 4.5519703807
MESH:D006333 Heart Failure Isoproterenol 4.0418097624
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.0915720958
MESH:D006558 Herpes Genitalis Estradiol 4.7015709030
MESH:D006689 Hodgkin Disease sodium arsenite 2.8912676792
MESH:D019584 Hot Flashes Estradiol 3.4217088409
MESH:D006849 Hydrocephalus Valproic Acid 4.5417688650
MESH:D006965 Hyperplasia Diethylstilbestrol 10.2612960047 14722030
MESH:D006965 Hyperplasia halofuginone 10.2611874485
MESH:D006973 Hypertension Amiloride 5.2419344079 18524855 15174897
MESH:D006973 Hypertension Cyclosporine 5.2410903974
MESH:D046110 Hypertension, Pregnancy-Induced Hydralazine 4.3116612254
MESH:D006984 Hypertrophy Isoproterenol 4.9012791704
MESH:D006985 Hyperventilation Terbutaline 5.7510895896
MESH:D007008 Hypokalemia Terbutaline 5.7717292646
MESH:D020514 Hypokalemic Periodic Paralysis Amiloride 5.5219822448
MESH:D007021 Hypospadias Diethylstilbestrol 4.2616002989
MESH:D007022 Hypotension Epinephrine 9.076740701
MESH:D007022 Hypotension Isoproterenol 9.076740701
MESH:D007246 Infertility Diethylstilbestrol 4.0515036965
MESH:D007248 Infertility, Male sodium arsenite 6.6312646999 15346721
MESH:D007248 Infertility, Male Theophylline 6.6316988215
MESH:D007249 Inflammation Amiloride 7.8217237260
MESH:D007249 Inflammation Diethylnitrosamine 7.8218785209
MESH:D007249 Inflammation ethylisopropylamiloride 7.8217237260
MESH:D007333 Insulin Resistance Estradiol 2.7616627594 16393666
MESH:D007410 Intestinal Diseases pimagedine 5.1311713966
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.1115604871
MESH:D007674 Kidney Diseases Cyclosporine 8.968314463 18776723 10903974
MESH:D007674 Kidney Diseases Estradiol 8.9615618244
MESH:D007674 Kidney Diseases sodium arsenite 8.9620008137
MESH:D007680 Kidney Neoplasms Cyclosporine 10.9212371664
MESH:D007680 Kidney Neoplasms Diethylstilbestrol 10.9216762066 15003126 14681315
MESH:D007680 Kidney Neoplasms Estradiol 10.9215610895
MESH:D007805 Language Development Disorders Methotrexate 4.809562676
MESH:D007859 Learning Disorders Diethylstilbestrol 3.7517184923
MESH:D053609 Lethargy Terbutaline 5.9810895896
MESH:D007938 Leukemia Genistein 2.8617468513 18980019
MESH:D015470 Leukemia, Myeloid, Acute Valproic Acid 2.1016294345 17596541
MESH:D056929 Liddle Syndrome Amiloride 5.6519344079
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.2418665156 20032147 19638242 18522880 18407596
MESH:D008103 Liver Cirrhosis halofuginone 10.2417180598
MESH:D008103 Liver Cirrhosis Methotrexate 10.2414986274
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4714659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Genistein 3.4717823541
MESH:D008106 Liver Cirrhosis, Experimental halofuginone 3.4712175628 18458672 16489207 14739098 11172339
MESH:D008107 Liver Diseases Diethylnitrosamine 2.0217034775
MESH:D008113 Liver Neoplasms Aflatoxin B1 9.6815890375 9163691 18177683 2125692
MESH:D008113 Liver Neoplasms Diethylnitrosamine 9.6820101389 19090486 21278145 19294768 19254457 2422723 20452335 19551842 19426721 18977376 19638242 18978307 18644402 20118626 19690152 20501860 18648771 19256749 19499222 21167192 19427195 21047994 15175105 20405173 19073162 20492335 16942905 10737359 18754104 20583210 19812893 2862719 12771043 20434301 12112319 19996281 20137499 15885732 19255062 19850985 9163691 19642983 19833225 21071580
MESH:D008113 Liver Neoplasms Diethylstilbestrol 9.6816712894 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 9.6815276417 16712894
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 5.338603461
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 5.3318164116 3124819 18079962 21159647 18253720 18282651 18775883 17942915 19126423 17854601 18544905 16842330 2563599 9362446 16267830 18093689 19519916 18308698 19009564 19539802 19004024 17174075
MESH:D008171 Lung Diseases sodium arsenite 2.9619095001
MESH:D017563 Lung Diseases, Interstitial Methotrexate 10.3618516814
MESH:D017563 Lung Diseases, Interstitial Valproic Acid 10.3617228818
MESH:D008175 Lung Neoplasms Aflatoxin B1 3.2514755239
MESH:D008175 Lung Neoplasms Diethylnitrosamine 3.256695378 20970405 20512841 21163286
MESH:D008175 Lung Neoplasms sodium arsenite 3.2517306315 17077188 19931552 16712894 15276417
MESH:D008181 Lupus Nephritis Diethylstilbestrol 4.8215166399
MESH:D008223 Lymphoma Diethylstilbestrol 7.1615700306
MESH:D008223 Lymphoma Methotrexate 7.1617352296
MESH:D052801 Male Urogenital Diseases Diethylstilbestrol 5.1816002989
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 5.4011408345 11807958 16891317 17203775
MESH:D008325 Mammary Neoplasms, Experimental Genistein 5.4012929590 14578162
MESH:D020149 Manganese Poisoning Estradiol 4.1519453300
MESH:D008545 Melanoma sodium arsenite 1.9916487513 19082730
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.4616801185
MESH:D008881 Migraine Disorders Valproic Acid 2.9618803445 18765137
MESH:D052016 Mucositis Methotrexate 4.9517488658
MESH:D009139 Musculoskeletal Abnormalities sodium arsenate 9.7118186108
MESH:D009139 Musculoskeletal Abnormalities Valproic Acid 9.718888407
MESH:D009190 Myelodysplastic Syndromes Valproic Acid 2.9717596541
MESH:D009203 Myocardial Infarction Genistein 5.8417141266
MESH:D009203 Myocardial Infarction Isoproterenol 5.8415740881 16584858 19595682 16697266 19172585 16538859 17052832
MESH:D015428 Myocardial Reperfusion Injury Estradiol 7.6916810080
MESH:D015428 Myocardial Reperfusion Injury Genistein 7.6917141266
MESH:D009361 Neoplasm Invasiveness Amiloride 4.9914644129
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.443581430 9029167
MESH:D009369 Neoplasms Diethylstilbestrol 4.7015313581
MESH:D009369 Neoplasms sodium arsenite 4.7011559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3520056578
MESH:D009389 Neovascularization, Pathologic Estradiol 3.4117289903
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.1117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.0119348381 18481113
MESH:D009421 Nervous System Malformations Diethylstilbestrol 14.7011399458
MESH:D009421 Nervous System Malformations Estradiol 14.7016427766 11399458
MESH:D009421 Nervous System Malformations Genistein 14.7016427766
MESH:D009436 Neural Tube Defects sodium arsenate 11.0519446573 18186108 11749123 10525206
MESH:D009436 Neural Tube Defects sodium arsenite 11.0512854658
MESH:D009436 Neural Tube Defects Valproic Acid 11.0516359493 8888407
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.0820387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 4.7920387270
MESH:D007752 Obstetric Labor, Premature Terbutaline 5.7814998686
MESH:D010024 Osteoporosis Genistein 3.0519401787
MESH:D015663 Osteoporosis, Postmenopausal Genistein 3.7916169203
MESH:D010051 Ovarian Neoplasms Estradiol 7.2719401270
MESH:D010051 Ovarian Neoplasms Genistein 7.2719005980
MESH:D010051 Ovarian Neoplasms sodium arsenite 7.2717306315 15276417
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.3016540662
MESH:D010900 Pituitary Diseases Diethylstilbestrol 4.8414722030
MESH:D010911 Pituitary Neoplasms Diethylstilbestrol 4.3515687265 16977796
MESH:D011230 Precancerous Conditions Cyclosporine 8.0412371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.042563599
MESH:D011297 Prenatal Exposure Delayed Effects Diethylstilbestrol 8.7217184923
MESH:D011297 Prenatal Exposure Delayed Effects Valproic Acid 8.7220603192
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.5920887781
MESH:D011471 Prostatic Neoplasms Diethylstilbestrol 2.1617136230 15046698 15846301
MESH:D011471 Prostatic Neoplasms Estradiol 2.1616740699
MESH:D011471 Prostatic Neoplasms Genistein 2.1615256057 15378649 16925846
MESH:D011471 Prostatic Neoplasms sodium arsenite 2.1616039940
MESH:D019310 Pseudolymphoma Valproic Acid 4.2111422049 12752131
MESH:D011565 Psoriasis Cyclosporine 5.5116882103
MESH:D011565 Psoriasis Methotrexate 5.5117410198
MESH:D029424 Pulmonary Disease, Chronic Obstructive Theophylline 4.8918983928
MESH:D011654 Pulmonary Edema Isoproterenol 10.4210903255
MESH:D011654 Pulmonary Edema Terbutaline 10.4210903255
MESH:D051437 Renal Insufficiency Methotrexate 4.3917352296
MESH:D012128 Respiratory Distress Syndrome, Adult Terbutaline 4.762878809
MESH:D012208 Rhabdomyosarcoma Valproic Acid 3.8719155313
MESH:D012512 Sarcoma, Ewing's Dactinomycin 4.7714601052
MESH:D012559 Schizophrenia Valproic Acid 2.0315737665 19110320
MESH:D012640 Seizures Valproic Acid 2.5314763951 11738929 3137016 16876388 11044598 17978042 1511512 15475178
MESH:D012772 Shock, Septic Terbutaline 5.173431524
MESH:D012871 Skin Diseases halofuginone 3.4311874485
MESH:D012878 Skin Neoplasms sodium arsenite 2.5519524636 18572023
MESH:D013088 Spermatocele Diethylstilbestrol 4.3816709447 16002989
MESH:D016135 Spinal Dysraphism sodium arsenite 8.7212854658
MESH:D016135 Spinal Dysraphism Valproic Acid 8.7219490988
MESH:D013226 Status Epilepticus Valproic Acid 4.2112833885
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D013276 Stomach Ulcer pimagedine 4.4318209962
MESH:D013576 Syndactyly Methotrexate 4.729562676
MESH:D013610 Tachycardia Terbutaline 5.1910895896
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.747505956
MESH:D013978 Tibial Fractures Estradiol 4.3519048282
MESH:D014178 Translocation, Genetic Valproic Acid 4.9017262798
MESH:D020194 Unverricht-Lundborg Syndrome Valproic Acid 4.193119515
MESH:D001749 Urinary Bladder Neoplasms Diethylstilbestrol 4.8317306315 16712894 16452187
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 4.8316452187 11723127 16712894 17306315
MESH:D014564 Urogenital Abnormalities Valproic Acid 4.328888407
MESH:D002583 Uterine Cervical Neoplasms Diethylstilbestrol 8.6116175088
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.6111813266
MESH:D014591 Uterine Diseases Diethylstilbestrol 4.8414652134
MESH:D014594 Uterine Neoplasms Diethylstilbestrol 3.7615809267 16690809
MESH:D014605 Uveitis Cyclosporine 3.651336536
MESH:D014625 Vaginal Neoplasms Diethylstilbestrol 4.1216002989 16513791
MESH:D014652 Vascular Diseases sodium arsenite 4.1017056641
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 4.8018097624
MESH:D020257 Ventricular Remodeling Isoproterenol 5.3618097624
MESH:D014985 Xerophthalmia Cyclosporine 4.1117120751
Pathway ID Pathway Name
KEGG:00330 Arginine and proline metabolism
KEGG:00340 Histidine metabolism
KEGG:00380 Tryptophan metabolism
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24416
    • No data
    Releated disease ID Related disease Name
    PA444546Hypersensitivity
    Releated drug ID Related drug Name
    PA449880histamine phosphate
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00594 blocker Riva-Amilzide 5/50 mg Sodium channel blockers;Diuretics
    DB03608 - Diminazene Trypanocidal Agents
    Drugbank ID Action Drug Name Description
    DB00594 inhibitor Riva-Amilzide 5/50 mg Sodium channel blockers;Diuretics
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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