AutismKB 2.0

Annotation Detail for RNF167


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Basic Information Top
Gene Symbol:RNF167 ( 5730408C10Rik,DKFZp566H073,RING105 )
Gene Full Name: ring finger protein 167
Band: 17p13.2
Quick LinksEntrez ID:26001; OMIM: 610431; Uniprot ID:RN167_HUMAN; ENSEMBL ID: ENSG00000108523; HGNC ID: 24544
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of RNF167 mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of RNF167 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of RNF167 mRNAaffects expression 17562736
C006632 arsenic trioxide arsenic trioxide results in increased expression of RNF167 mRNAincreases expression 20458559
D012402 Rotenone Rotenone results in increased expression of RNF167 mRNAincreases expression 19013527
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3519825857 11798837
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.0416206674
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7311589617
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 6.9216705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 6.9216705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 6.923084413
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 6.9215073043 16217749 11135700 14691202 15553829
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4712490120
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.006135515
MESH:D015179 Colorectal Neoplasms arsenic trioxide 1.8620501625
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.5618551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.5618551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5015213294
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 6.6718551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.6721346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.6712594235 11529661 16109766 14550746 19420014 14725611 19370779 12540782 17562736 11461765 16227642 11743745 16081117 16393943 10915739 12392966 19923254 11739529 2444490 19416960 11287661 16781746 19739265 12153990 11834606 18713872 17522070 10663392 17906064 10774834 15968718 16485898 19085960 12958197 16177239 12705907 15619225 18071297 19164858 11421492 14986274
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver arsenic trioxide 3.6615073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7016904648
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D007674 Kidney Diseases Acetaminophen 2.3815629191 12587719
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.3916705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.3916705839
MESH:D007938 Leukemia arsenic trioxide 2.9815070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1712560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.8516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 4.1319077051
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1819850784 17050201 16968895 20471514 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4316966277 12018890 15336539 16891316 17869043 12712474 16331271 16112521 19075265 19642359 11161223 19035177 16330433 17217047 15748426 17712046 15622746 11468182 12679006 15213294 19225113 17107899 16823087 9834237 17649720
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7916882451
MESH:D008107 Liver Diseases Acetaminophen 1.6912587719 16611625 11587558 12969438 16610002 19784758 19014921 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.5817185352 16871587
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 4.977678174
MESH:D008113 Liver Neoplasms arsenic trioxide 4.9714682389
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.652876786 6135515 2876784
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.6520377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6215213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009101 Multiple Myeloma arsenic trioxide 3.3514977855 19417148 15949261 11468182 19549372
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.2818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.3216882451 16105982
MESH:D009336 Necrosis 2,4-dinitrotoluene 12.2118551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 12.2118551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4016624393
MESH:D009410 Nerve Degeneration Rotenone 4.1518619942 15790535 17356569
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3310525206
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 10.0612819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 10.0616049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 2.4916624393 12452020 19769630
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 2.6215580305
MESH:D010235 Paraganglioma arsenic trioxide 4.5719927285
MESH:D010300 Parkinson Disease Rotenone 3.0816140633 11535288 19114014 16412576 15451049 18619942 18191903 19232380 11445065
MESH:D020734 Parkinsonian Disorders Rotenone 4.4215574749 15927086 18197244 15795934
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2219131511
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4016646077
MESH:D012640 Seizures 2,4-dinitrotoluene 6.6518551238
MESH:D012640 Seizures 2,6-dinitrotoluene 6.6518551238
MESH:D013274 Stomach Neoplasms arsenic trioxide 1.8617007042
MESH:D013964 Thyroid Neoplasms arsenic trioxide 3.3619014326
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5015213294
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.9816049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 8.9816049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.9812845720 20435036 11780464 12973940
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.8610091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.8610091137
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
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Syndromic Genes

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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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