AutismKB 2.0

Annotation Detail for MOXD1


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Basic Information Top
Gene Symbol:MOXD1 ( DKFZp564G202,MOX,PRO5780,dJ248E1.1 )
Gene Full Name: monooxygenase, DBH-like 1
Band: 6q23.2
Quick LinksEntrez ID:26002; OMIM: 609000; Uniprot ID:MOXD1_HUMAN; ENSEMBL ID: ENSG00000079931; HGNC ID: 21063
Relate to Another Database: SFARIGene; denovo-db
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D020122 tert-Butylhydroperoxide tert-Butylhydroperoxide results in decreased expression of MOXD1 mRNAdecreases expression 15336504
D004041 Dietary Fats Dietary Fats results in increased expression of MOXD1 mRNAincreases expression 18042831
C041786 palm oil palm oil results in increased expression of MOXD1 mRNAincreases expression 18042831
D010634 Phenobarbital NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MOXD1 mRNA]affects reaction|increases expression 19482888
D010634 Phenobarbital Phenobarbital results in increased expression of MOXD1 mRNAincreases expression 19482888
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of MOXD1 mRNAaffects binding|decreases expression|increases activity 19710929
D014810 Vitamin E Vitamin E results in increased expression of MOXD1 mRNAincreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.906195326
MESH:D055371 Acute Lung Injury pirinixic acid 3.4718653653
MESH:D018248 Adenoma, Liver Cell Phenobarbital 11.7117620307
MESH:D018248 Adenoma, Liver Cell pirinixic acid 11.7116434500
MESH:D001161 Arteriosclerosis Dietary Fats 4.3115238619
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.4719483382
MESH:D001943 Breast Neoplasms Dietary Fats 2.2520435547
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.3516050911
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 1.9420935162 17173139 6705139 20007298 1701930
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.674080065
MESH:D002779 Cholestasis pirinixic acid 3.0519176532
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5518249437
MESH:D050171 Dyslipidemias Dietary Fats 3.6718367378
MESH:D004421 Dystonia Phenobarbital 4.361851702
MESH:C538011 Eales disease Vitamin E 5.229068938
MESH:D004487 Edema pirinixic acid 2.8012083418
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.533659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.3911558140 3922381
MESH:D004827 Epilepsy Phenobarbital 3.0320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.836401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.677750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.483659116
MESH:D005234 Fatty Liver Dietary Fats 8.8018296743 17967931 19551842 19004024
MESH:D005234 Fatty Liver pirinixic acid 8.8019236843 20131406
MESH:D005355 Fibrosis Dietary Fats 3.9418296743
MESH:D006330 Heart Defects, Congenital Vitamin E 3.1316080930
MESH:D006333 Heart Failure pirinixic acid 2.7120558911
MESH:D006529 Hepatomegaly Phenobarbital 9.9016109766
MESH:D006529 Hepatomegaly pirinixic acid 9.9019772884 16221962 18467677 19176532
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7916490937 16863852
MESH:D019584 Hot Flashes Vitamin E 4.4914716179
MESH:D006937 Hypercholesterolemia Dietary Fats 3.9221332399
MESH:D006943 Hyperglycemia pirinixic acid 3.4920558911
MESH:D006949 Hyperlipidemias Dietary Fats 3.9721332399
MESH:D007249 Inflammation Dietary Fats 2.5720412841
MESH:D007251 Influenza, Human Vitamin E 4.7316624496
MESH:D007333 Insulin Resistance Dietary Fats 7.8911836018 18457598
MESH:D007333 Insulin Resistance pirinixic acid 7.8916306350
MESH:D007674 Kidney Diseases Vitamin E 2.9612488133
MESH:D008103 Liver Cirrhosis Dietary Fats 7.1818296743
MESH:D008103 Liver Cirrhosis Phenobarbital 7.1821047994
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4515474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.4516169303
MESH:D008107 Liver Diseases Phenobarbital 2.2319363144
MESH:D008113 Liver Neoplasms Phenobarbital 4.8021047994 8742319 19812893 15975961 19073162 19482888
MESH:D008113 Liver Neoplasms pirinixic acid 4.8016377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 2.8817172636 2563599 1399818 18308698 6150874
MESH:D008171 Lung Diseases Vitamin E 3.3716863852
MESH:D008175 Lung Neoplasms Vitamin E 1.9011062179
MESH:D009135 Muscular Diseases pirinixic acid 3.9216239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2519151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1916411023
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.9417484760
MESH:D009369 Neoplasms pirinixic acid 2.0817405874
MESH:D009765 Obesity Dietary Fats 4.6416723640 21332399 20518802 17217161 19632207 18674790 11836018 18457598 20132043
MESH:D009765 Obesity pirinixic acid 4.6420558911
MESH:D010018 Osteomalacia Phenobarbital 4.8317016548
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5816965848
MESH:D011230 Precancerous Conditions Phenobarbital 3.912563599
MESH:D011471 Prostatic Neoplasms Vitamin E 3.2515084515
MESH:D019310 Pseudolymphoma Phenobarbital 5.0212752131
MESH:D015427 Reperfusion Injury pirinixic acid 2.5219058328
MESH:D012640 Seizures Phenobarbital 2.894039156 3137016 16876388 11442880
MESH:D003294 Seizures, Febrile Phenobarbital 5.286407741
MESH:D012871 Skin Diseases Vitamin E 2.5018709164
MESH:D012878 Skin Neoplasms tert-Butylhydroperoxide 2.818532709
MESH:D020521 Stroke Vitamin E 3.7716517955
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.291399818
MESH:D015430 Weight Gain Dietary Fats 4.0216723640
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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