AutismKB 2.0

Annotation Detail for ACOT11


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Basic Information Top
Gene Symbol:ACOT11 ( BFIT,DKFZp667O1916,KIAA0707,STARD14,THEA,THEM1 )
Gene Full Name: acyl-CoA thioesterase 11
Band: 1p32.3
Quick LinksEntrez ID:26027; OMIM: 606803; Uniprot ID:ACO11_HUMAN; ENSEMBL ID: ENSG00000162390; HGNC ID: 18156
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
No data
No data
Desease Name
CHEMDEPENDENCY
smoking cessation
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of ACOT11 mRNAaffects expression 17562736
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of ACOT11 mRNAdecreases expression 20064835
D002251 Carbon Tetrachloride Carbon Tetrachloride results in increased expression of ACOT11 mRNAincreases expression 17484886
C006253 pirinixic acid pirinixic acid results in decreased expression of ACOT11 mRNAdecreases expression 17426115
D018038 Sodium Selenite Sodium Selenite results in decreased expression of ACOT11 mRNAdecreases expression 18175754
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D055371 Acute Lung Injury pirinixic acid 3.5218653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0520127859 20464547
MESH:D000236 Adenoma Benzo(a)pyrene 2.846695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.0216434500
MESH:D000799 Angioedema Acetaminophen 4.4510982225
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.5619183758
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5219483382
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 2.0017474063 20146248
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.2615673190 16124888 16227642 16097048 15700767 18705752 15721981 16011737 16192424 16050911 10355542 3786805
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.973084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 2.9718788625
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1320419170
MESH:D002386 Cataract Acetaminophen 2.7710977129
MESH:D002779 Cholestasis pirinixic acid 3.0819176532
MESH:D019457 Chromosome Breakage Sodium Selenite 5.2415894690
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5618249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 4.1016285004
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 6.7316081117 11421492 15968718 2444490 19085960 19370779 16177239 16227642 14725611 19923254 16781746 19420014 17906064 12594235 11461765 17562736 19416960 12958197 19739265 11834606 16109766 19164858 18713872 14550746 18071297 12392966 11743745 10774834 11739529 16485898 11287661 15619225 12705907 12153990 10663392 16393943 11529661 14986274 10915739 12540782 17522070
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 6.7319085960 10915739 16227642 15998439 6623471 6884620 7440962 7120509 16177239 15027814 3732212 7179309 11566570 3786805 19336974 21278145 9327722 10092053 4309450 2869522 17522070 15968718
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.7315131321
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.7119426721
MESH:D004487 Edema pirinixic acid 2.8512083418
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0716530937
MESH:D005234 Fatty Liver Carbon Tetrachloride 8.9415959796 16239168 12631006 17595544 61145 12795759 16045604 19224547
MESH:D005234 Fatty Liver pirinixic acid 8.9420131406 19236843
MESH:D005355 Fibrosis Carbon Tetrachloride 3.9418705752
MESH:D005756 Gastritis Acetaminophen 4.2916983495
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 2.8220471113
MESH:D006333 Heart Failure pirinixic acid 2.7320558911
MESH:D006505 Hepatitis Carbon Tetrachloride 4.0319110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 3.4816221962 19772884 18467677 19176532
MESH:D006930 Hyperalgesia Acetaminophen 2.9916870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 5.0716899240
MESH:D006943 Hyperglycemia pirinixic acid 3.5320558911
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.5715338365
MESH:D007333 Insulin Resistance pirinixic acid 8.0416306350
MESH:D007333 Insulin Resistance Sodium Selenite 8.0414714311
MESH:D007674 Kidney Diseases Acetaminophen 2.3812587719 15629191
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.9817334410 11903743 21278145 16943688 11408273 17157831 17174718 16221502 16239168
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.4115931870 17721639 18054572 17761835 14716496 17557913 17823541 15338365 16011737 18279442 18263696 18429990 17976157 17805973 18376398 10355542 12666154 18395914 15370692 18339082 18277467 18205269 16033810 18412020 16015684 17708605 18420326 15818738 18006644 12632514 15959796 12546737 15052691 15123356 18472094 16027843 18395095 12898905 16136751 16248980 18251166 15673190 17869086 18210741 12609069 15362042 17481882 15730626 17900296 16116963 15925388 18705752 18472332 15057751 12389079 14724832 17922224 12958196 17714472 15996030 14620537 18156304 17698563 15650968 14512876 15893842 16638106 13678700 12445418 11481614 12649538 20821823 16097048 12741479 14748882 15876570 14716833 18187930 12586293 17640975 17766677 12445421 17525996 18481824 12667390 18166357 12632512 16192424 18418968 17631135 17565644 17944888 18317297
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4115474484
MESH:D008107 Liver Diseases Acetaminophen 4.1416611625 19014921 12969438 19784758 16610002 19460945 12587719 11587558
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1416964402 16246199 15830285 17285989 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.6515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.5916871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.5914706259 16899240
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 8.0321137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.0319294768
MESH:D008113 Liver Neoplasms pirinixic acid 8.0316377806 15890375 20007298
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 2.8112014681 15583823
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 1.5718816296 17053015 20464547 20064080 6695378 20869020 18569708 18520028 20135361
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.4614737004
MESH:D008546 Melanoma, Experimental Acetaminophen 4.0519513568
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.4616381670
MESH:D009135 Muscular Diseases pirinixic acid 3.9916239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2619151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2216411023
MESH:D009369 Neoplasms Benzo(a)pyrene 5.3311141357
MESH:D009369 Neoplasms pirinixic acid 5.3317405874
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1818514411
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D010146 Pain Acetaminophen 2.6916870215
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1517292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1518760546
MESH:D015427 Reperfusion Injury pirinixic acid 2.5319058328
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 2.5119755658 10029692
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 2.2917053015
MESH:D014581 Urticaria Acetaminophen 3.3810982225
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA38303
    • No data
    Releated disease ID Related disease Name
    PA446714Neoplasm, Residual
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

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    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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