Annotation Detail for ZNF451
Basic Information
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| Gene Symbol: | ZNF451 ( COASTER,FLJ23421,FLJ53246,FLJ90693,KIAA0576,KIAA1702,MGC26701,dJ417I1.1 ) |
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| Gene Full Name: | zinc finger protein 451 |
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| Band: | 6p12.1 |
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| Quick Links | Entrez ID:26036; OMIM: NA; Uniprot ID:ZN451_HUMAN; ENSEMBL ID: ENSG00000112200; HGNC ID: 21091 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
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| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene results in increased expression of ZNF451 mRNA | increases expression | 20406850
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZNF451 mRNA | decreases expression | 20018196
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.74 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.74 | 20889678 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.78 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.07 | 21346803 18551238 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.16 | 20426865 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
3.41 | 16705839 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.29 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.82 | 2876786 6135515 2876784 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.75 | 18551238 7678174 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.94 | 16049721 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.85 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.43 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.20 | 10091137 |
Related Pathway Information