AutismKB 2.0

Annotation Detail for ANKRD17


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:ANKRD17 ( FLJ22206,GTAR,KIAA0697,NY-BR-16 )
Gene Full Name: ankyrin repeat domain 17
Band: 4q13.3
Quick LinksEntrez ID:26057; OMIM: NA; Uniprot ID:ANR17_HUMAN; ENSEMBL ID: ENSG00000132466; HGNC ID: 23575
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000643 Ammonium Chloride Ammonium Chloride affects the expression of ANKRD17 mRNAaffects expression 16483693
D001104 Arbutin Arbutin results in increased expression of ANKRD17 mRNAincreases expression 17103032
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ANKRD17 mRNAdecreases expression 19150397
C055494 caffeic acid phenethyl ester caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA]decreases reaction|increases expression 20360939
D004052 Diethylnitrosamine caffeic acid phenethyl ester inhibits the reaction [Diethylnitrosamine results in increased expression of ANKRD17 mRNA]decreases reaction|increases expression 20360939
D004052 Diethylnitrosamine Diethylnitrosamine results in increased expression of ANKRD17 mRNAincreases expression 20360939
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANKRD17 mRNAaffects cotreatment|increases expression 17942748
C051890 irinotecan irinotecan analog results in decreased expression of ANKRD17 mRNAdecreases expression 18927307
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ANKRD17 mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1811752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.9018287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.3217505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8614692618
MESH:D000236 Adenoma Diethylnitrosamine 2.9810737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 11.2118056438 19061943 17620307 19052882 17162532 16434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 11.2116835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1711748828
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7711256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8015885639
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.2912125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1715340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.9115746008
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9417474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9420435547
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.9916835633
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 1.873084413 16681979 20524982 18691550 18393292 21159647 17761372 16779866 20084675 18971187 18506893 11831363 17428255 18665156 19052882 10737359 16807293 19418558 18210153 19822196 18785209 20007298 20935162 20512989 19701751 17162532 19519916 20101231 19394651 19107877 16502159 19383236 17173139 18494052 19208518 20432363 16698587 3581430 16878318 19335982 20214788 18056438 16569478 16540662 19919837 10672840 19539802 18788625 17055752 18978308 20514400 17138121 20727157 17978847 16288022 16935385 16328049 16830150 19171122
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4916120746 18850075 18670907
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.2120889678
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 7.212727394 21159647 17174075 7505956
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 10.0519052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 10.0516835633
MESH:D002779 Cholestasis Ethinyl Estradiol 3.0517110522 17681005 15861022 16919318 17333356 11677210 16105132
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1915340226 8697196 12621046 15668235 16354765
MESH:D003110 Colonic Neoplasms irinotecan 2.6217725105 17287894
MESH:D015179 Colorectal Neoplasms irinotecan 2.3617454858 16391804 17159606 16303861 18509181 18259882 15273666
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2714669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2620055451 10048152 15322242
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.3820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.3817107852
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 3.9319107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 3.9320420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9311462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.6111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2816714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4712538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.259294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.4916302075
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 2.1220426865
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1911564622
MESH:D005234 Fatty Liver Diethylnitrosamine 8.5221071580 20387270
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.5215345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7611858732
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 3.2520067830
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9710696789
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4410048152 11294989
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5811000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 3.2015340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.428697196 16354765 16959395 15340226 18606429
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 1.9818850075 18670907
MESH:D007021 Hypospadias Ethinyl Estradiol 4.1216569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.7212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6417937319
MESH:D007249 Inflammation Diethylnitrosamine 5.2718785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 5.2712200463 12878042
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.8110783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5816580747
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 3.6715369732
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 4.1416766008
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 2.9418522880 18665156 20032147 18407596 19638242
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 1.2412878042
MESH:D008107 Liver Diseases Diethylnitrosamine 2.1517034775
MESH:D008113 Liver Neoplasms Diethylnitrosamine 4.6615885732 19426721 2422723 18644402 19090486 21278145 19073162 19638242 20434301 20492335 19850985 18754104 19551842 19812893 16942905 20405173 19833225 10737359 20501860 9163691 19427195 19499222 18978307 20452335 20118626 19256749 21047994 20101389 18648771 20583210 12771043 19255062 18977376 19690152 19642983 12112319 2862719 19294768 20137499 21167192 19254457 15175105 19996281 21071580
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 4.6616984957
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 6.2319004024 19519916 18093689 16267830 17854601 16842330 2563599 9362446 19126423 18282651 3124819 19539802 21159647 18308698 17174075 19009564 18164116 18253720 17942915 18079962 18544905 18775883
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 6.2312151625
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.3120970405 6695378 20512841 21163286
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 2.3119555203 11884234
MESH:D052016 Mucositis irinotecan 5.3517159606
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.2112213967
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 6.233581430 9029167
MESH:D009362 Neoplasm Metastasis irinotecan 6.2318259882
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4914600291
MESH:D009447 Neuroblastoma irinotecan 3.598761367
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.5420387270
MESH:D017599 Neuroectodermal Tumors irinotecan 5.078761367
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.4920387270
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4916540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.6212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8418163543
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.772563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.5311399792 11896295 11222880 11118676
MESH:D011537 Pruritus Ethinyl Estradiol 3.6516919318 15861022
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.1218990726
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 2.1416192470
MESH:D013088 Spermatocele Ethinyl Estradiol 4.3216709447
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.6718456281
MESH:D013274 Stomach Neoplasms irinotecan 2.6715723263
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3715669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2812697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.167505956
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5814692618
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7814671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.6215886252
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved