Annotation Detail for DCAF4
Basic Information
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| Gene Symbol: | DCAF4 ( DKFZp434K114,MGC20547,MGC46524,WDR21,WDR21A ) |
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| Gene Full Name: | DDB1 and CUL4 associated factor 4 |
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| Band: | 14q24.2 |
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| Quick Links | Entrez ID:26094; OMIM: NA; Uniprot ID:DCAF4_HUMAN; ENSEMBL ID: ENSG00000119599; HGNC ID: 20229 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene results in increased expression of DCAF4 mRNA | increases expression | 20406850
|
| D016572 |
Cyclosporine |
Cyclosporine results in increased expression of DCAF4 mRNA | increases expression | 20106945
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
1.79 | 16705839 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.67 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
Cyclosporine |
7.67 | 12371664 |
| MESH:D002779 |
Cholestasis |
|
Cyclosporine |
3.28 | 19486331 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
4.78 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
2.07 | 18551238 21346803 |
| MESH:D005234 |
Fatty Liver |
|
Cyclosporine |
3.40 | 19224547 |
| MESH:D005355 |
Fibrosis |
|
Cyclosporine |
3.90 | 12639820 12168785 |
| MESH:D005885 |
Gingival Hyperplasia |
|
Cyclosporine |
5.11 | 8708960 |
| MESH:D006457 |
Hemoglobinuria, Paroxysmal |
|
Cyclosporine |
5.31 | 15720958 |
| MESH:D006973 |
Hypertension |
|
Cyclosporine |
2.24 | 10903974 |
| MESH:D007638 |
Keratoconjunctivitis Sicca |
|
Cyclosporine |
5.51 | 15604871 |
| MESH:D007674 |
Kidney Diseases |
|
Cyclosporine |
2.58 | 8314463 10903974 18776723 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.75 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
Cyclosporine |
8.75 | 12371664 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
2.29 | 7678174 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.82 | 2876784 2876786 6135515 |
| MESH:D008664 |
Metal Metabolism, Inborn Errors |
|
Cyclosporine |
5.86 | 16801185 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
4.75 | 18551238 7678174 |
| MESH:D009402 |
Nephrosis, Lipoid |
|
Cyclosporine |
5.51 | 17954296 |
| MESH:D009404 |
Nephrotic Syndrome |
|
Cyclosporine |
3.75 | 18481113 19348381 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
3.94 | 16049721 |
| MESH:D011230 |
Precancerous Conditions |
|
Cyclosporine |
3.69 | 12371664 |
| MESH:D011565 |
Psoriasis |
|
Cyclosporine |
2.35 | 16882103 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
2.85 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
2.43 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
5.20 | 10091137 |
| MESH:D014605 |
Uveitis |
|
Cyclosporine |
5.05 | 1336536 |
| MESH:D014985 |
Xerophthalmia |
|
Cyclosporine |
5.51 | 17120751 |
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