Annotation Detail for LRIT1
Basic Information
Top
| Gene Symbol: | LRIT1 ( DKFZp434K091,FIGLER9,LRRC21,PAL ) |
|---|
| Gene Full Name: | leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 |
|---|
| Band: | 10q23.1 |
|---|
| Quick Links | Entrez ID:26103; OMIM: NA; Uniprot ID:LRIT1_HUMAN; ENSEMBL ID: ENSG00000148602; HGNC ID: 23404 |
|---|
| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of LRIT1 mRNA | affects expression | 17562736
|
| D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of LRIT1 mRNA | affects expression | 16483693
|
| D004997 |
Ethinyl Estradiol |
Ethinyl Estradiol affects the expression of LRIT1 mRNA | affects expression | 15212814
|
| D010634 |
Phenobarbital |
NR1I3 protein affects the reaction [Phenobarbital results in decreased expression of LRIT1 mRNA] | affects reaction|decreases expression | 19482888
|
| D010634 |
Phenobarbital |
Phenobarbital results in decreased expression of LRIT1 mRNA | decreases expression | 19482888
|
| C025299 |
polyphenols |
polyphenols results in decreased expression of LRIT1 mRNA | decreases expression | 16293270
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000014 |
Abnormalities, Drug-Induced |
|
Phenobarbital |
3.98 | 6195326 |
| MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.10 | 18287403 |
| MESH:D000152 |
Acne Vulgaris |
|
Ethinyl Estradiol |
4.55 | 17505938 |
| MESH:D000230 |
Adenocarcinoma |
|
Ethinyl Estradiol |
1.88 | 14692618 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
Phenobarbital |
4.51 | 17620307 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D001161 |
Arteriosclerosis |
|
Ethinyl Estradiol |
3.95 | 11256880 |
| MESH:D001169 |
Arthritis, Experimental |
|
Ethinyl Estradiol |
2.86 | 15885639 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
3.01 | 3084413 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Phenobarbital |
3.01 | 6705139 17173139 20007298 20935162 1701930 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002493 |
Central Nervous System Diseases |
|
Phenobarbital |
4.74 | 4080065 |
| MESH:D002779 |
Cholestasis |
|
Ethinyl Estradiol |
3.13 | 17110522 16105132 15861022 17681005 11677210 16919318 17333356 |
| MESH:D003110 |
Colonic Neoplasms |
|
polyphenols |
2.72 | 16293270 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
4.28 | 11743745 19739265 15619225 10663392 19923254 12705907 12153990 17522070 19164858 10915739 14550746 16781746 10774834 14725611 19085960 17906064 11739529 15968718 19370779 11461765 12392966 18071297 17562736 11421492 12540782 19416960 12594235 11287661 16485898 11834606 16393943 16227642 19420014 12958197 2444490 16081117 16177239 14986274 16109766 11529661 18713872 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
polyphenols |
4.28 | 19370779 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D004421 |
Dystonia |
|
Phenobarbital |
4.41 | 1851702 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Ethinyl Estradiol |
3.63 | 12538720 |
| MESH:D004831 |
Epilepsies, Myoclonic |
|
Phenobarbital |
4.59 | 3659116 |
| MESH:D004828 |
Epilepsies, Partial |
|
Phenobarbital |
4.48 | 3922381 11558140 |
| MESH:D004827 |
Epilepsy |
|
Phenobarbital |
3.04 | 20417680 |
| MESH:D004832 |
Epilepsy, Absence |
|
Phenobarbital |
3.87 | 6401628 |
| MESH:D017029 |
Epilepsy, Complex Partial |
|
Phenobarbital |
4.74 | 7750514 |
| MESH:D004830 |
Epilepsy, Tonic-Clonic |
|
Phenobarbital |
4.56 | 3659116 |
| MESH:D005234 |
Fatty Liver |
|
Ethinyl Estradiol |
3.18 | 15345470 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006529 |
Hepatomegaly |
|
Phenobarbital |
3.97 | 16109766 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D007021 |
Hypospadias |
|
Ethinyl Estradiol |
4.29 | 16569931 16945680 |
| MESH:D007247 |
Infertility, Female |
|
Ethinyl Estradiol |
3.87 | 12013081 |
| MESH:D007248 |
Infertility, Male |
|
Ethinyl Estradiol |
2.71 | 17937319 |
| MESH:D007249 |
Inflammation |
|
polyphenols |
3.22 | 16366677 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D008103 |
Liver Cirrhosis |
|
Phenobarbital |
3.07 | 21047994 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
7.01 | 11587558 19460945 16610002 19014921 12587719 19784758 16611625 12969438 |
| MESH:D008107 |
Liver Diseases |
|
Phenobarbital |
7.01 | 19363144 |
| MESH:D008107 |
Liver Diseases |
|
polyphenols |
7.01 | 16698588 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 17185352 16871587 |
| MESH:D008113 |
Liver Neoplasms |
|
Phenobarbital |
2.41 | 19482888 19073162 21047994 19812893 15975961 8742319 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
Phenobarbital |
2.90 | 6150874 17172636 2563599 1399818 18308698 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D020191 |
Myoclonic Epilepsies, Progressive |
|
Phenobarbital |
5.02 | 17484760 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D010018 |
Osteomalacia |
|
Phenobarbital |
4.90 | 17016548 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D010190 |
Pancreatic Neoplasms |
|
Phenobarbital |
2.59 | 16965848 |
| MESH:D016584 |
Panic Disorder |
|
Ethinyl Estradiol |
4.09 | 11578682 |
| MESH:D011230 |
Precancerous Conditions |
|
Phenobarbital |
3.95 | 2563599 |
| MESH:D011537 |
Pruritus |
|
Ethinyl Estradiol |
3.85 | 16919318 15861022 |
| MESH:D019310 |
Pseudolymphoma |
|
Phenobarbital |
5.11 | 12752131 |
| MESH:D012640 |
Seizures |
|
Phenobarbital |
2.92 | 16876388 3137016 4039156 11442880 |
| MESH:D003294 |
Seizures, Febrile |
|
Phenobarbital |
5.36 | 6407741 |
| MESH:D013088 |
Spermatocele |
|
Ethinyl Estradiol |
4.55 | 16709447 |
| MESH:D013705 |
Temporomandibular Joint Disorders |
|
polyphenols |
5.86 | 17997062 |
| MESH:D019851 |
Thrombophilia |
|
Ethinyl Estradiol |
4.02 | 11994571 |
| MESH:D013927 |
Thrombosis |
|
Ethinyl Estradiol |
3.48 | 15669648 |
| MESH:D013964 |
Thyroid Neoplasms |
|
Phenobarbital |
3.32 | 1399818 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
| MESH:D014594 |
Uterine Neoplasms |
|
Ethinyl Estradiol |
3.74 | 14692618 |
| MESH:D020246 |
Venous Thrombosis |
|
Ethinyl Estradiol |
3.91 | 14671159 15869587 |
Related Pathway Information