AutismKB 2.0

Annotation Detail for TCTN3


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Basic Information Top
Gene Symbol:TCTN3 ( C10orf61,DKFZp564D116,TECT3 )
Gene Full Name: tectonic family member 3
Band: 10q24.1
Quick LinksEntrez ID:26123; OMIM: NA; Uniprot ID:TECT3_HUMAN; ENSEMBL ID: ENSG00000119977; HGNC ID: 24519
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D001151 Arsenic Arsenic affects the expression of TCTN3 mRNAaffects expression 18414638
C017947 sodium arsenite sodium arsenite affects the expression of TCTN3 mRNAaffects expression 19590694
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 5.7715276417
MESH:D018246 Adrenocortical Adenoma Arsenic 17.8017306315
MESH:D018246 Adrenocortical Adenoma sodium arsenite 17.8016712894 17306315
MESH:D020261 Arsenic Poisoning Arsenic 2.9712569548 16835338 18414634 16251483
MESH:D050197 Atherosclerosis Arsenic 3.5119371607 12928151
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.8315504454 17687452
MESH:D006528 Carcinoma, Hepatocellular Arsenic 3.4017306315 16507464
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 3.4017306315 16507464 15276417
MESH:D002294 Carcinoma, Squamous Cell Arsenic 5.2018922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 5.2018572023
MESH:D002295 Carcinoma, Transitional Cell Arsenic 4.5818640142
MESH:D002318 Cardiovascular Diseases Arsenic 3.7719152805 15738583 17938729
MESH:D002340 Carotid Artery Diseases Arsenic 4.7818022660 16973168
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 3.3120056578 19524636
MESH:D005534 Foot Diseases Arsenic 6.636392382
MESH:D005833 Genital Neoplasms, Female sodium arsenite 5.5716452187
MESH:D006689 Hodgkin Disease sodium arsenite 3.6212676792
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.9617050553
MESH:D006973 Hypertension Arsenic 3.0116076760 11953799 9931084
MESH:D006987 Hypesthesia Arsenic 6.6316093927
MESH:D007248 Infertility, Male sodium arsenite 3.2915346721 12646999
MESH:D007642 Keratosis Arsenic 5.8816930632 12749816
MESH:D007674 Kidney Diseases sodium arsenite 3.0420008137
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 3.8517339181
MESH:D008107 Liver Diseases Arsenic 2.6311134558
MESH:D008113 Liver Neoplasms Arsenic 5.2916368122
MESH:D008113 Liver Neoplasms sodium arsenite 5.2915276417 16712894
MESH:D008171 Lung Diseases sodium arsenite 3.4819095001
MESH:D008175 Lung Neoplasms Arsenic 2.7617306315 19168569 17976673
MESH:D008175 Lung Neoplasms sodium arsenite 2.7619931552 15276417 17077188 16712894 17306315
MESH:D008545 Melanoma sodium arsenite 2.0819082730 16487513
MESH:D017202 Myocardial Ischemia Arsenic 4.3915371236
MESH:D009369 Neoplasms sodium arsenite 2.6911559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 4.4320056578
MESH:D009436 Neural Tube Defects Arsenic 8.4616620997
MESH:D009436 Neural Tube Defects sodium arsenite 8.4612854658
MESH:D020078 Neurogenic Inflammation Arsenic 4.9817056641
MESH:D010051 Ovarian Neoplasms Arsenic 5.4217306315
MESH:D010051 Ovarian Neoplasms sodium arsenite 5.4217306315 15276417
MESH:D010523 Peripheral Nervous System Diseases Arsenic 4.8516093927
MESH:D016491 Peripheral Vascular Diseases Arsenic 5.8815371236 16905509 6392382
MESH:D011471 Prostatic Neoplasms Arsenic 3.3316140617
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.3316039940
MESH:D011507 Proteinuria Arsenic 4.6121343184
MESH:D012871 Skin Diseases Arsenic 2.8417453740 19834688 17548696 6392382 17050553 16353154 18709164 16702368 15952646 16759981 17938729
MESH:D012878 Skin Neoplasms Arsenic 6.5817976673 17050553 16251483 19538983 15504454 17029826
MESH:D012878 Skin Neoplasms sodium arsenite 6.5819524636 18572023
MESH:D016135 Spinal Dysraphism sodium arsenite 4.1812854658
MESH:D001749 Urinary Bladder Neoplasms Arsenic 5.7917976673 18640142 15987713 19322015 11144890 17306315 19429237
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.7916452187 11723127 17306315 16712894
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 4.2711813266
MESH:D014652 Vascular Diseases Arsenic 15.0317056641
MESH:D014652 Vascular Diseases sodium arsenite 15.0317056641
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA162405513
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450379mercaptopurine
    PA450428methotrexate
    Drug Bank Top

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    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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