Annotation Detail for GAPVD1
Basic Information
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| Gene Symbol: | GAPVD1 ( DKFZp434C212,GAPEX5,KIAA1521,MGC138847,MGC138848,RAP6 ) |
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| Gene Full Name: | GTPase activating protein and VPS9 domains 1 |
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| Band: | 9q33.3 |
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| Quick Links | Entrez ID:26130; OMIM: 611714; Uniprot ID:GAPD1_HUMAN; ENSEMBL ID: ENSG00000165219; HGNC ID: 23375 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| C016403 |
2,4-dinitrotoluene |
2,4-dinitrotoluene affects the expression of GAPVD1 mRNA | affects expression | 21346803
|
| C023514 |
2,6-dinitrotoluene |
2,6-dinitrotoluene affects the expression of GAPVD1 mRNA | affects expression | 21346803
|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of GAPVD1 mRNA | affects expression | 17562736
|
| D015123 |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of GAPVD1 mRNA | decreases expression | 20018196
19150397
|
| C023036 |
perfluorooctanoic acid |
perfluorooctanoic acid results in increased expression of GAPVD1 mRNA | increases expression | 17560707
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of GAPVD1 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.36 | 10982225 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
3.89 | 19015723 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,4-dinitrotoluene |
4.73 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
2,6-dinitrotoluene |
4.73 | 16705839 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
4.73 | 3084413 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.75 | 10977129 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
2,6-dinitrotoluene |
7.35 | 6135515 |
| MESH:D002471 |
Cell Transformation, Neoplastic |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
7.35 | 20889678 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.72 | 14966744 |
| MESH:D003490 |
Cyanosis |
|
2,4-dinitrotoluene |
12.32 | 18551238 |
| MESH:D003490 |
Cyanosis |
|
2,6-dinitrotoluene |
12.32 | 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,4-dinitrotoluene |
6.62 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
2,6-dinitrotoluene |
6.62 | 21346803 18551238 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
6.62 | 10774834 16227642 2444490 14725611 10663392 16109766 19923254 19739265 15619225 10915739 14550746 11461765 12153990 17906064 12540782 16781746 19420014 16081117 11739529 11421492 11743745 15968718 12392966 11529661 18713872 11287661 12594235 19416960 19164858 12958197 16393943 12705907 17562736 18071297 19370779 14986274 16485898 11834606 16177239 17522070 19085960 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.62 | 19426721 |
| MESH:D004487 |
Edema |
|
perfluorooctanoic acid |
3.90 | 17259670 12083418 |
| MESH:D004938 |
Esophageal Neoplasms |
|
7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide |
2.13 | 20426865 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.19 | 16983495 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.40 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
5.82 | 16417039 |
| MESH:D006529 |
Hepatomegaly |
|
perfluorooctanoic acid |
4.51 | 3609246 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
8.72 | 16870215 |
| MESH:D006930 |
Hyperalgesia |
|
perfluorooctanoic acid |
8.72 | 12083418 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.24 | 16467254 |
| MESH:D007249 |
Inflammation |
|
perfluorooctanoic acid |
3.20 | 12083418 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.36 | 15629191 12587719 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,4-dinitrotoluene |
8.27 | 16705839 |
| MESH:D007680 |
Kidney Neoplasms |
|
2,6-dinitrotoluene |
8.27 | 16705839 |
| MESH:D007984 |
Leydig Cell Tumor |
|
perfluorooctanoic acid |
14.53 | 8812269 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
14.53 | 16417039 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 12587719 19784758 11587558 19014921 16611625 12969438 16610002 19460945 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.54 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
2,6-dinitrotoluene |
5.14 | 7678174 |
| MESH:D008113 |
Liver Neoplasms |
|
perfluorooctanoic acid |
5.14 | 18709148 14757943 |
| MESH:D008114 |
Liver Neoplasms, Experimental |
|
2,6-dinitrotoluene |
2.72 | 2876784 6135515 2876786 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
3.98 | 19513568 |
| MESH:D009336 |
Necrosis |
|
2,4-dinitrotoluene |
11.94 | 18551238 |
| MESH:D009336 |
Necrosis |
|
2,6-dinitrotoluene |
11.94 | 18551238 7678174 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.14 | 18514411 |
| MESH:D052556 |
Niemann-Pick Disease, Type C |
|
perfluorooctanoic acid |
5.37 | 9802331 |
| MESH:D009784 |
Occupational Diseases |
|
2,4-dinitrotoluene |
9.92 | 16049721 12819281 |
| MESH:D009784 |
Occupational Diseases |
|
2,6-dinitrotoluene |
9.92 | 16049721 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.65 | 16870215 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
perfluorooctanoic acid |
11.52 | 17132714 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
11.52 | 19015723 18220299 18042343 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.40 | 18220299 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.40 | 18629315 |
| MESH:D012640 |
Seizures |
|
2,4-dinitrotoluene |
6.56 | 18551238 |
| MESH:D012640 |
Seizures |
|
2,6-dinitrotoluene |
6.56 | 18551238 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,4-dinitrotoluene |
5.36 | 16049721 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
2,6-dinitrotoluene |
5.36 | 16049721 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,4-dinitrotoluene |
13.58 | 10091137 |
| MESH:D014571 |
Urologic Neoplasms |
|
2,6-dinitrotoluene |
13.58 | 10091137 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.33 | 10982225 |
Related Pathway Information