AutismKB 2.0

Annotation Detail for ZBTB20


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Basic Information Top
Gene Symbol:ZBTB20 ( DKFZp566F123,DPZF,FLJ26458,HOF,ODA-8S,ZNF288 )
Gene Full Name: zinc finger and BTB domain containing 20
Band: 3q13.31
Quick LinksEntrez ID:26137; OMIM: 606025; Uniprot ID:ZBT20_HUMAN; ENSEMBL ID: ENSG00000181722; HGNC ID: 13503
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of ZBTB20 mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of ZBTB20 mRNAaffects expression 17562736
D001104 Arbutin Arbutin results in increased expression of ZBTB20 mRNAincreases expression 17103032
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of ZBTB20 mRNAdecreases expression 20018196
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of ZBTB20 mRNAdecreases expression 17557909
D005472 Fluorouracil Fluorouracil results in decreased expression of ZBTB20 mRNAdecreases expression 16510598
C051890 irinotecan irinotecan analog results in decreased expression of ZBTB20 mRNAdecreases expression 18927307
C006253 pirinixic acid pirinixic acid results in increased expression of ZBTB20 mRNAincreases expression 16985257
D014810 Vitamin E Vitamin E results in decreased expression of ZBTB20 mRNAdecreases expression 19244175
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.2617505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.3418653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.4914692618
MESH:D000230 Adenocarcinoma Fluorouracil 4.4917638652
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.7616434500
MESH:D000740 Anemia Fluorouracil 3.9015504547 16511603 17963324
MESH:D000799 Angioedema Acetaminophen 4.1610982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.7211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.7815885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.3519483382
MESH:D001943 Breast Neoplasms Fluorouracil 2.4518357371 16557594 15136595 16595493 18608205 19217205 16110121
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 4.1916050911
MESH:D002276 Carcinoid Tumor Fluorouracil 4.9916051944
MESH:D002277 Carcinoma Fluorouracil 3.7317121937
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 4.7116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 4.713084413
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 4.7117971768 16799960 17088986 17045692 16332177 18930000
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 3.1018695887
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 2.5416757204 16280240 17066447 18986760
MESH:D002386 Cataract Acetaminophen 2.6910977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 7.106135515
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.1020889678
MESH:D002779 Cholestasis Ethinyl Estradiol 8.2515861022 16919318 17110522 11677210 17333356 17681005 16105132
MESH:D002779 Cholestasis pirinixic acid 8.2519176532
MESH:D003110 Colonic Neoplasms Fluorouracil 4.0717287894 18772588 17016597 17725105 16340194 15001691 17169374 16510598 17018589 17172411
MESH:D003110 Colonic Neoplasms irinotecan 4.0717725105 17287894
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.7718509181 18448328 15148649 16282729 15289873 16524972 17016601 20501625 17594712 18802399 18383874 17695437 16303861 16331619 17401013 16391804 17094418 17255274 17454858 18949393 18288408 14970324
MESH:D015179 Colorectal Neoplasms irinotecan 2.7716391804 17454858 17159606 18509181 15273666 16303861 18259882
MESH:D019465 Craniofacial Abnormalities Vitamin E 1.9219769572
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2818551238
MESH:D007644 Darier Disease Fluorouracil 5.0816733453
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5118249437
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 3.8921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.8911287661 16485898 18071297 16081117 14550746 12153990 12705907 10774834 11529661 12540782 11739529 17562736 10663392 15968718 11743745 19085960 18713872 15619225 10915739 12392966 12594235 11834606 14725611 16177239 16781746 16227642 19923254 19164858 17906064 19420014 11461765 19416960 12958197 11421492 16109766 19370779 19739265 14986274 17522070 16393943 2444490
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.4219426721
MESH:C538011 Eales disease Vitamin E 5.029068938
MESH:D004487 Edema pirinixic acid 2.6812083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.4212538720
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 4.6620426865
MESH:D004938 Esophageal Neoplasms Fluorouracil 4.6615173087 16481741 16337965 17638652 16785472
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.2415345470
MESH:D005234 Fatty Liver pirinixic acid 8.2420131406 19236843
MESH:D005756 Gastritis Acetaminophen 3.9916983495
MESH:D005910 Glioma Fluorouracil 2.9416145905
MESH:D006258 Head and Neck Neoplasms Fluorouracil 3.5215102660 15162350 18337622
MESH:D006330 Heart Defects, Congenital Vitamin E 3.0816080930
MESH:D006333 Heart Failure pirinixic acid 2.6520558911
MESH:D006529 Hepatomegaly pirinixic acid 3.2519772884 19176532 18467677 16221962
MESH:D006548 Hernia, Diaphragmatic Vitamin E 2.7616863852 16490937
MESH:D019584 Hot Flashes Vitamin E 4.2914716179
MESH:D006930 Hyperalgesia Acetaminophen 2.8616870215
MESH:D006943 Hyperglycemia pirinixic acid 3.3820558911
MESH:D007021 Hypospadias Ethinyl Estradiol 4.0716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.6812013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.6217937319
MESH:D007251 Influenza, Human Vitamin E 4.5316624496
MESH:D007333 Insulin Resistance pirinixic acid 2.7616306350
MESH:D007674 Kidney Diseases Acetaminophen 6.3315629191 12587719
MESH:D007674 Kidney Diseases Vitamin E 6.3312488133
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.0616705839
MESH:D007680 Kidney Neoplasms Fluorouracil 8.0616985049
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.4315474484
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 2.4316169303
MESH:D008107 Liver Diseases Acetaminophen 1.6711587558 19014921 12587719 19784758 16610002 16611625 12969438 19460945
MESH:D017114 Liver Failure, Acute Acetaminophen 3.4316871587 17185352
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 7.837678174
MESH:D008113 Liver Neoplasms Fluorouracil 7.8317045692 18383874 16603448 15113037
MESH:D008113 Liver Neoplasms pirinixic acid 7.8315890375 20007298 16377806
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 2.662876786 6135515 2876784
MESH:D008171 Lung Diseases Vitamin E 3.3116863852
MESH:D008175 Lung Neoplasms Fluorouracil 2.6415246190
MESH:D008175 Lung Neoplasms Vitamin E 2.6411062179
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 5.0815086387
MESH:D008546 Melanoma, Experimental Acetaminophen 3.8319513568
MESH:D009062 Mouth Neoplasms Fluorouracil 3.7916757204 18986760
MESH:D052016 Mucositis irinotecan 5.2917159606
MESH:D009135 Muscular Diseases pirinixic acid 3.7616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2119151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1016411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.157678174 18551238
MESH:D009362 Neoplasm Metastasis irinotecan 3.2418259882
MESH:D009369 Neoplasms Fluorouracil 5.2918600527 16928823 18239605
MESH:D009369 Neoplasms pirinixic acid 5.2917405874
MESH:D009447 Neuroblastoma irinotecan 3.578761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.0418514411
MESH:D017599 Neuroectodermal Tumors irinotecan 5.018761367
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.5716436463
MESH:D009765 Obesity pirinixic acid 1.8520558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6216049721
MESH:D010146 Pain Acetaminophen 2.5616870215
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7216500647 16929163 19003803 15113037
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.9111578682
MESH:D011471 Prostatic Neoplasms Fluorouracil 3.3018626508 19082440
MESH:D011471 Prostatic Neoplasms Vitamin E 3.3015084515
MESH:D011537 Pruritus Ethinyl Estradiol 3.6016919318 15861022
MESH:D012004 Rectal Neoplasms Fluorouracil 4.1918286688 18722050 15538739 16160472
MESH:D015427 Reperfusion Injury pirinixic acid 2.4719058328
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6718551238
MESH:D012871 Skin Diseases Vitamin E 2.4818709164
MESH:D013088 Spermatocele Ethinyl Estradiol 4.2616709447
MESH:D013274 Stomach Neoplasms Fluorouracil 2.7618396642 16424979 19015929 19084572 17522103 17498489 16951190 17172411 15786421 18567086
MESH:D013274 Stomach Neoplasms irinotecan 2.7615723263
MESH:D020521 Stroke Vitamin E 3.6816517955
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.8411994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.3315669648
MESH:D014062 Tongue Neoplasms Fluorouracil 4.1816280240
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 2.3516049721
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6010091137
MESH:D014581 Urticaria Acetaminophen 3.2010982225
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.0716803524
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.5414692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.7515869587 14671159
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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