AutismKB 2.0

Annotation Detail for NOC2L


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Basic Information Top
Gene Symbol:NOC2L ( DKFZp564C186,FLJ35172,NET15,NET7,NIR )
Gene Full Name: nucleolar complex associated 2 homolog (S. cerevisiae)
Band: 1p36.33
Quick LinksEntrez ID:26155; OMIM: 610770; Uniprot ID:NOC2L_HUMAN; ENSEMBL ID: ENSG00000188976; HGNC ID: 24517
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of NOC2L mRNAaffects expression 17562736
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of NOC2L mRNAaffects cotreatment|affects expression 17602206
D003907 Dexamethasone Dexamethasone results in decreased expression of NOC2L mRNAdecreases expression 12782123
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of NOC2L mRNAaffects cotreatment|affects expression 17602206
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000236 Adenoma Diethylnitrosamine 3.0510737359 6695378
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 4.5319052882 16434500 17162532 18056438 17620307 19061943
MESH:D000799 Angioedema Acetaminophen 4.5710982225
MESH:D001169 Arthritis, Experimental Dexamethasone 3.7617659584
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D001943 Breast Neoplasms Diethylnitrosamine 2.1917474063
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 2.993084413
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 2.9920007298 19335982 16830150 19539802 20512989 10672840 20524982 19919837 16502159 19052882 17162532 19701751 20101231 3581430 16540662 18788625 20935162 16935385 19107877 20514400 19383236 16779866 17428255 17978847 20432363 20214788 18494052 21159647 16807293 16878318 18056438 17173139 18691550 16288022 16328049 19822196 11831363 3084413 16698587 18506893 19519916 18393292 19208518 16569478 16681979 19171122 18971187 17761372 18978308 18210153 19394651 17138121 20084675 20727157 18665156 17055752 10737359 19418558 18785209
MESH:D002386 Cataract Acetaminophen 2.7910977129
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 3.127505956 2727394 17174075 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 4.0519052882
MESH:D003110 Colonic Neoplasms Dexamethasone 2.5415824018
MESH:D019465 Craniofacial Abnormalities Dexamethasone 2.2917728286
MESH:D017449 Dermatitis, Allergic Contact Dexamethasone 3.9612438553
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 2.2620387270
MESH:D003967 Diarrhea Dexamethasone 4.207237001
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 4.0519416960 14986274 11461765 11743745 18071297 19923254 16781746 12153990 14725611 10774834 10915739 16177239 15968718 11739529 11421492 16393943 17522070 19420014 12705907 19164858 10663392 16485898 12958197 19085960 11529661 16109766 17906064 11834606 11287661 17562736 19739265 12540782 12392966 12594235 15619225 16081117 16227642 19370779 2444490 14550746 18713872
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 4.0519107877
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.8219426721
MESH:D004485 Eczema Dexamethasone 4.9712438553
MESH:D004487 Edema Dexamethasone 3.8219703484
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.8416302075
MESH:D005234 Fatty Liver Diethylnitrosamine 3.6121071580 20387270
MESH:D005756 Gastritis Acetaminophen 4.4016983495
MESH:D006548 Hernia, Diaphragmatic Dexamethasone 3.187520565
MESH:D006930 Hyperalgesia Acetaminophen 3.0216870215
MESH:D006973 Hypertension Dexamethasone 3.0517042910
MESH:D007249 Inflammation Dexamethasone 5.8811099482 8960868
MESH:D007249 Inflammation Diethylnitrosamine 5.8818785209
MESH:D007674 Kidney Diseases Acetaminophen 2.4015629191 12587719
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 3.0118665156 18407596 20032147 18522880 19638242
MESH:D008106 Liver Cirrhosis, Experimental Dexamethasone 2.2716718785
MESH:D008107 Liver Diseases Acetaminophen 4.1719460945 16611625 19784758 11587558 19014921 12587719 16610002 12969438
MESH:D008107 Liver Diseases Diethylnitrosamine 4.1717034775
MESH:D017114 Liver Failure, Acute Acetaminophen 3.6317185352 16871587
MESH:D008113 Liver Neoplasms Clofibric Acid 5.1717602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 5.1720101389 20137499 19551842 19426721 19256749 19690152 19642983 19073162 21167192 18754104 18977376 19812893 20501860 21047994 18978307 20452335 20118626 19638242 9163691 12112319 18648771 21278145 19254457 12771043 19255062 19833225 19427195 19294768 19996281 18644402 20492335 19499222 21071580 10737359 20405173 15885732 2422723 20583210 2862719 19090486 15175105 20434301 19850985 16942905
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 2.8519009564 2563599 18093689 18282651 16267830 9362446 3124819 19126423 18775883 21159647 19539802 17174075 18079962 16842330 18544905 19519916 18253720 18164116 19004024 17942915 18308698 17854601
MESH:D008175 Lung Neoplasms Dexamethasone 2.7215824018 11195469
MESH:D008175 Lung Neoplasms Diethylnitrosamine 2.7220512841 20970405 21163286 6695378
MESH:D008546 Melanoma, Experimental Acetaminophen 4.1319513568
MESH:D009101 Multiple Myeloma Dexamethasone 3.7815744524 16118317 15867202
MESH:D009190 Myelodysplastic Syndromes Dexamethasone 3.749809623
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.699029167 3581430
MESH:D019636 Neurodegenerative Diseases Acetaminophen 9.3518514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 9.3520387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.8420387270
MESH:D010146 Pain Acetaminophen 2.7316870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.5316540662
MESH:D011230 Precancerous Conditions Diethylnitrosamine 3.922563599
MESH:D054198 Precursor Cell Lymphoblastic Leukemia-Lymphoma Dexamethasone 3.7421297632
MESH:D012128 Respiratory Distress Syndrome, Adult Dexamethasone 4.4811700416 18379247
MESH:D013272 Stomach Diseases Dexamethasone 4.9515472012
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7618456281
MESH:D013276 Stomach Ulcer Dexamethasone 3.9115138204
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.297505956
MESH:D014581 Urticaria Acetaminophen 3.4410982225
MESH:D014605 Uveitis Dexamethasone 5.541336536
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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