AutismKB 2.0

Annotation Detail for IFT172


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Basic Information Top
Gene Symbol:IFT172 ( DKFZp434A163,KIAA1179,SLB,osm-1,wim )
Gene Full Name: intraflagellar transport 172 homolog (Chlamydomonas)
Band: 2p23.3
Quick LinksEntrez ID:26160; OMIM: 607386; Uniprot ID:IF172_HUMAN; ENSEMBL ID: ENSG00000138002; HGNC ID: 30391
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
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Pathway IDPathway Name
200147Hedgehog signaling events mediated by Gli proteins
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of IFT172 mRNAincreases expression 17942748
D005038 Ethylnitrosourea Ethylnitrosourea results in increased mutagenesis of IFT172 geneincreases mutagenesis 15755804
C014707 nitrosobenzylmethylamine nitrosobenzylmethylamine results in decreased expression of IFT172 mRNAdecreases expression 17616710
C006253 pirinixic acid pirinixic acid results in decreased expression of IFT172 mRNAdecreases expression 17426115
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.6617505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.5818653653
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8814692618
MESH:D000236 Adenoma Ethylnitrosourea 3.926695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 4.1116434500
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 4.0211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.8915885639
MESH:D001778 Blood Coagulation Disorders pirinixic acid 3.5719483382
MESH:D001927 Brain Diseases Ethylnitrosourea 5.2814991843
MESH:D001932 Brain Neoplasms Ethylnitrosourea 4.6816357521 15144691 18412241 16436596 16651633
MESH:D002471 Cell Transformation, Neoplastic Ethylnitrosourea 3.9816003739
MESH:D016543 Central Nervous System Neoplasms Ethylnitrosourea 6.7117160924
MESH:D002779 Cholestasis Ethinyl Estradiol 8.7317333356 17681005 11677210 16919318 15861022 16105132 17110522
MESH:D002779 Cholestasis pirinixic acid 8.7319176532
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5718249437
MESH:D004476 Ectodermal Dysplasia Ethylnitrosourea 6.7118357618
MESH:D004487 Edema pirinixic acid 2.9012083418
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 3.6912538720
MESH:D004938 Esophageal Neoplasms nitrosobenzylmethylamine 2.8515547721 15547733 15150132 15264214 15623463 16510608 16805852 15878914 16704527
MESH:D005234 Fatty Liver Ethinyl Estradiol 8.9915345470
MESH:D005234 Fatty Liver pirinixic acid 8.9920131406 19236843
MESH:D005909 Glioblastoma Ethylnitrosourea 4.0716436596
MESH:D005910 Glioma Ethylnitrosourea 3.6218412241 16651633 16357521
MESH:D006333 Heart Failure pirinixic acid 2.7620558911
MESH:D006529 Hepatomegaly pirinixic acid 3.5519772884 16221962 18467677 19176532
MESH:D006943 Hyperglycemia pirinixic acid 3.5820558911
MESH:D007021 Hypospadias Ethinyl Estradiol 4.3716945680 16569931
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.9212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.7317937319
MESH:D007333 Insulin Resistance pirinixic acid 2.8716306350
MESH:D007680 Kidney Neoplasms Ethylnitrosourea 4.2717379185
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 1.3515474484
MESH:D008113 Liver Neoplasms pirinixic acid 1.9320007298 15890375 16377806
MESH:D008175 Lung Neoplasms Ethylnitrosourea 2.6316019985 17703301 16271038 6695378
MESH:D008223 Lymphoma Ethylnitrosourea 4.2215790496
MESH:D016399 Lymphoma, T-Cell Ethylnitrosourea 5.6115375218
MESH:D008325 Mammary Neoplasms, Experimental Ethylnitrosourea 3.7410838139 10767621 18041768
MESH:D008579 Meningioma Ethylnitrosourea 6.7117943659
MESH:D009135 Muscular Diseases pirinixic acid 4.0716239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.2516411023
MESH:D009369 Neoplasms pirinixic acid 2.1117405874
MESH:D009374 Neoplasms, Experimental Ethylnitrosourea 4.9616707424
MESH:D009442 Neurilemmoma Ethylnitrosourea 6.0516003739 16651423 17160924
MESH:D009765 Obesity pirinixic acid 1.8820558911
MESH:D009837 Oligodendroglioma Ethylnitrosourea 6.7117160924
MESH:D016584 Panic Disorder Ethinyl Estradiol 4.1511578682
MESH:D011537 Pruritus Ethinyl Estradiol 3.9416919318 15861022
MESH:D015427 Reperfusion Injury pirinixic acid 2.5519058328
MESH:D013088 Spermatocele Ethinyl Estradiol 4.6616709447
MESH:D013274 Stomach Neoplasms nitrosobenzylmethylamine 2.3317575124 12958204
MESH:D019851 Thrombophilia Ethinyl Estradiol 4.0811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.5215669648
MESH:D013953 Thymus Neoplasms Ethylnitrosourea 5.7915790496
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.8014692618
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.9715869587 14671159
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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