Annotation Detail for GTPBP5
Basic Information
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| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001151 |
Arsenic |
Arsenic affects the expression of GTPBP5 mRNA | affects expression | 18414638
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of GTPBP5 mRNA | affects binding|increases activity|increases expression | 19710929
|
| C025643 |
vinclozolin |
vinclozolin affects the expression of GTPBP5 mRNA | affects expression | 19015723
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.64 | 18653653 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.22 | 16434500 |
| MESH:D018246 |
Adrenocortical Adenoma |
|
Arsenic |
6.08 | 17306315 |
| MESH:D001008 |
Anxiety Disorders |
|
vinclozolin |
4.00 | 19015723 |
| MESH:D020261 |
Arsenic Poisoning |
|
Arsenic |
2.96 | 12569548 16835338 18414634 16251483 |
| MESH:D050197 |
Atherosclerosis |
|
Arsenic |
3.48 | 19371607 12928151 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.63 | 19483382 |
| MESH:D002280 |
Carcinoma, Basal Cell |
|
Arsenic |
3.80 | 17687452 15504454 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Arsenic |
2.32 | 17306315 16507464 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Arsenic |
2.78 | 17687452 15504454 18922899 |
| MESH:D002295 |
Carcinoma, Transitional Cell |
|
Arsenic |
4.52 | 18640142 |
| MESH:D002318 |
Cardiovascular Diseases |
|
Arsenic |
3.74 | 15738583 19152805 17938729 |
| MESH:D002340 |
Carotid Artery Diseases |
|
Arsenic |
4.73 | 18022660 16973168 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.15 | 19176532 |
| MESH:D003456 |
Cryptorchidism |
|
vinclozolin |
4.93 | 14966744 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.59 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.96 | 12083418 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.25 | 19236843 20131406 |
| MESH:D005534 |
Foot Diseases |
|
Arsenic |
6.43 | 6392382 |
| MESH:D030342 |
Genetic Diseases, Inborn |
|
vinclozolin |
5.68 | 16973722 |
| MESH:D005832 |
Genital Diseases, Male |
|
vinclozolin |
6.17 | 16417039 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.78 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.64 | 19176532 16221962 18467677 19772884 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.63 | 20558911 |
| MESH:D017488 |
Hyperkeratosis, Epidermolytic |
|
Arsenic |
4.90 | 17050553 |
| MESH:D006973 |
Hypertension |
|
Arsenic |
3.00 | 16076760 9931084 11953799 |
| MESH:D006987 |
Hypesthesia |
|
Arsenic |
6.43 | 16093927 |
| MESH:D007248 |
Infertility, Male |
|
vinclozolin |
3.32 | 16467254 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.90 | 16306350 |
| MESH:D007642 |
Keratosis |
|
Arsenic |
5.73 | 16930632 12749816 |
| MESH:D015473 |
Leukemia, Promyelocytic, Acute |
|
Arsenic |
3.82 | 17339181 |
| MESH:D007984 |
Leydig Cell Tumor |
|
vinclozolin |
5.47 | 16417039 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Arsenic |
2.62 | 11134558 |
| MESH:D008113 |
Liver Neoplasms |
|
Arsenic |
5.05 | 16368122 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
5.05 | 20007298 15890375 16377806 |
| MESH:D008175 |
Lung Neoplasms |
|
Arsenic |
2.21 | 17976673 17306315 19168569 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.16 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.29 | 19151258 |
| MESH:D017202 |
Myocardial Ischemia |
|
Arsenic |
4.35 | 15371236 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.29 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
2.12 | 17405874 |
| MESH:D009436 |
Neural Tube Defects |
|
Arsenic |
3.72 | 16620997 |
| MESH:D020078 |
Neurogenic Inflammation |
|
Arsenic |
4.90 | 17056641 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.89 | 20558911 |
| MESH:D010051 |
Ovarian Neoplasms |
|
Arsenic |
2.85 | 17306315 |
| MESH:D010523 |
Peripheral Nervous System Diseases |
|
Arsenic |
4.76 | 16093927 |
| MESH:D016491 |
Peripheral Vascular Diseases |
|
Arsenic |
5.73 | 16905509 6392382 15371236 |
| MESH:D011297 |
Prenatal Exposure Delayed Effects |
|
vinclozolin |
4.64 | 18220299 18042343 19015723 |
| MESH:D011469 |
Prostatic Diseases |
|
vinclozolin |
5.68 | 18220299 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Arsenic |
3.54 | 16140617 |
| MESH:D011472 |
Prostatitis |
|
vinclozolin |
5.68 | 18629315 |
| MESH:D011507 |
Proteinuria |
|
Arsenic |
4.53 | 21343184 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.56 | 19058328 |
| MESH:D012871 |
Skin Diseases |
|
Arsenic |
2.83 | 6392382 19834688 15952646 17050553 16759981 17938729 17453740 17548696 16702368 18709164 16353154 |
| MESH:D012878 |
Skin Neoplasms |
|
Arsenic |
3.18 | 17029826 19538983 17976673 16251483 17050553 15504454 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Arsenic |
2.95 | 11144890 17306315 19322015 18640142 17976673 19429237 15987713 |
| MESH:D014652 |
Vascular Diseases |
|
Arsenic |
5.48 | 17056641 |
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