AutismKB 2.0

Annotation Detail for AMD1


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Basic Information Top
Gene Symbol:AMD1 ( ADOMETDC,AMD,DKFZp313L1234,FLJ26964,SAMDC )
Gene Full Name: adenosylmethionine decarboxylase 1
Band: 6q21
Quick LinksEntrez ID:262; OMIM: 180980; Uniprot ID:DCAM_HUMAN; ENSEMBL ID: ENSG00000123505; HGNC ID: 457
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
ARGSPECAT-PWYspermine biosynthesis
BSUBPOLYAMSYN-PWYspermidine biosynthesis
Pathway IDPathway Name
hsa00330Arginine and proline metabolism
hsa01100Metabolic pathways
hsa00270Cysteine and methionine metabolism
Pathway IDPathway Name
Metabolism of amino acids and derivatives
No data
No data
Pathway IDPathway Name
500786Metabolism of polyamines
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1831Prostate cancer
2045Bipolar disorder
2069Schizophrenia
No data
No data
No data
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C009505 4,4'-diaminodiphenylmethane 4,4'-diaminodiphenylmethane results in decreased expression of AMD1 mRNAdecreases expression 18648102
D000082 Acetaminophen Acetaminophen affects the expression of AMD1 mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of AMD1 proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of AMD1 mRNAaffects expression 16483693
D015123 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of AMD1 mRNAdecreases expression 20382639
19150397
20018196
C053541 bicalutamide bicalutamide results in increased expression of AMD1 mRNAincreases expression 15790403
D005419 Flavonoids Flavonoids results in decreased expression of AMD1 mRNAdecreases expression 18035473
D005492 Folic Acid Folic Acid results in increased activity of AMD1 proteinincreases activity 17371283
D005492 Folic Acid Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein]decreases reaction|increases activity 17371283
D007213 Indomethacin Indomethacin results in decreased expression of AMD1 mRNAdecreases expression 16984733
C006253 pirinixic acid pirinixic acid results in decreased expression of AMD1 mRNAdecreases expression 20059764
17426115
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of AMD1 mRNA]decreases expression|increases reaction 20059764
D012110 Reserpine Reserpine inhibits the reaction [Folic Acid results in increased activity of AMD1 protein]decreases reaction|increases activity 17371283
C009250 sevoflurane sevoflurane affects the expression of AMD1 mRNAaffects expression 15967596
D014212 Tretinoin Tretinoin results in decreased expression of AMD1 mRNAdecreases expression 16054129
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 3.6818287403
MESH:D058186 Acute Kidney Injury Folic Acid 4.4117003819 16316344 16595132
MESH:D055371 Acute Lung Injury pirinixic acid 3.2018653653
MESH:D000230 Adenocarcinoma Indomethacin 2.8016537180
MESH:D000236 Adenoma 4,4'-diaminodiphenylmethane 11.633712494
MESH:D000236 Adenoma Folic Acid 11.6316963246
MESH:D000236 Adenoma Indomethacin 11.6311497255
MESH:D018248 Adenoma, Liver Cell pirinixic acid 3.6016434500
MESH:D000505 Alopecia Tretinoin 3.6815955085
MESH:D016301 Alveolar Bone Loss Indomethacin 5.5117225004
MESH:D000544 Alzheimer Disease Folic Acid 4.7117116317
MESH:D000544 Alzheimer Disease Indomethacin 4.7117627676 15579461
MESH:D000799 Angioedema Acetaminophen 3.9810982225
MESH:D001014 Aortic Aneurysm Indomethacin 4.9410231640
MESH:D017544 Aortic Aneurysm, Abdominal Indomethacin 4.9810388637
MESH:D001161 Arteriosclerosis Reserpine 5.9610729376
MESH:D018771 Arthralgia Indomethacin 5.302160914
MESH:D001169 Arthritis, Experimental Tretinoin 3.1216412693
MESH:D001172 Arthritis, Rheumatoid Indomethacin 4.8311248219
MESH:D001172 Arthritis, Rheumatoid Tretinoin 4.8316292516
MESH:D001249 Asthma Tretinoin 2.3616456186
MESH:D001321 Autistic Disorder Acetaminophen 2.1618445737
MESH:D001321 Autistic Disorder Folic Acid 2.1621388746
MESH:D001471 Barrett Esophagus Tretinoin 4.5016935849
MESH:D001477 Bartter Syndrome Indomethacin 5.0910684365
MESH:D001660 Biliary Tract Diseases 4,4'-diaminodiphenylmethane 5.1511289319 1440618
MESH:D001778 Blood Coagulation Disorders pirinixic acid 9.2519483382
MESH:D001778 Blood Coagulation Disorders Tretinoin 9.2516206674 16197459
MESH:D001929 Brain Edema Indomethacin 5.1611481608
MESH:D002545 Brain Ischemia Indomethacin 4.5312524144
MESH:D001943 Breast Neoplasms Folic Acid 2.1516777985
MESH:D001943 Breast Neoplasms Indomethacin 2.1517401462
MESH:D001943 Breast Neoplasms Reserpine 2.1511921183
MESH:D001943 Breast Neoplasms Tretinoin 2.1516873071 16443354 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.7116813970
MESH:D002056 Burns Indomethacin 4.8110459503
MESH:D002100 Cachexia Indomethacin 5.1215625704 16537180 15141370 11239499
MESH:D018236 Carcinoma, Embryonal Tretinoin 5.2916168501
MESH:D006528 Carcinoma, Hepatocellular 4,4'-diaminodiphenylmethane 9.013581430 7296757
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 9.013084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 9.0121507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Indomethacin 9.0116391822
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 9.011917145
MESH:D018827 Carcinoma, Lewis Lung Indomethacin 4.8411053908
MESH:D018276 Carcinoma, Medullary Indomethacin 5.4711352223 18791128 14736730
MESH:D002292 Carcinoma, Renal Cell 4,4'-diaminodiphenylmethane 6.747296757
MESH:D002292 Carcinoma, Renal Cell Indomethacin 6.7417341418
MESH:D002294 Carcinoma, Squamous Cell Indomethacin 4.9312636206 15482327
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 4.9316051514 16096774
MESH:D002318 Cardiovascular Diseases Folic Acid 4.0016755160
MESH:D002386 Cataract Acetaminophen 7.3810977129
MESH:D002386 Cataract Tretinoin 7.3817460283
MESH:D002471 Cell Transformation, Neoplastic 4,4'-diaminodiphenylmethane 6.837505956
MESH:D002471 Cell Transformation, Neoplastic 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 6.8320889678
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.7116129372
MESH:D002764 Cholecystitis Indomethacin 5.3011181007
MESH:D002779 Cholestasis 4,4'-diaminodiphenylmethane 8.0419486331 9022650
MESH:D002779 Cholestasis pirinixic acid 8.0419176532
MESH:D002822 Choriocarcinoma Tretinoin 5.2916461808
MESH:D002971 Cleft Lip Folic Acid 4.0221254359
MESH:D002972 Cleft Palate Folic Acid 6.418946559 21254359
MESH:D002972 Cleft Palate Tretinoin 6.419407595
MESH:D003092 Colitis Tretinoin 3.8117035595
MESH:D003110 Colonic Neoplasms Indomethacin 2.6015936596 15786552 11260862 15963497 15625704 15637740
MESH:D015179 Colorectal Neoplasms Folic Acid 3.0017116713 16963246 16985020 17087956 17245555
MESH:D015179 Colorectal Neoplasms Indomethacin 3.0012606626 17054584 11197048 18059344
MESH:D018352 Coronavirus Infections Indomethacin 5.8517302372
MESH:D019465 Craniofacial Abnormalities Tretinoin 1.8210589399 8800419 16925845 14991402 17551590 9224671 9125849 9211117 9142499 9664655
MESH:D017449 Dermatitis, Allergic Contact 4,4'-diaminodiphenylmethane 2.908970840 12868966 11298694 8156756 14531868 18759878 11906362 2524372
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4618249437
MESH:D003877 Dermatitis, Contact 4,4'-diaminodiphenylmethane 3.583621924 2952479
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 3.1516886840
MESH:D003967 Diarrhea Indomethacin 3.897237001 7907874
MESH:D056486 Drug-Induced Liver Injury 4,4'-diaminodiphenylmethane 3.7811289319 18692083 18648102 9022650 6482804 18289764 9328219 8291058 9653073 16192314 1440618 6679447 7440962
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 3.7816109766 12153990 18071297 19416960 16081117 12540782 19739265 14550746 11287661 11739529 12705907 14725611 10915739 11743745 16177239 16781746 15968718 11461765 19085960 18713872 17906064 12594235 10663392 19923254 19164858 14986274 19420014 19370779 11529661 12392966 16485898 11421492 12958197 17562736 16227642 11834606 2444490 10774834 17522070 16393943 15619225
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.2319426721
MESH:D004374 Ductus Arteriosus, Patent Indomethacin 5.2717190690 16133044 18043480 16326151 18446180 12774134
MESH:D004381 Duodenal Ulcer Indomethacin 4.2311535926 16699067 11991626 17351913 17045617 11595415 17329845 11595431 17151854 17202747 10671773
MESH:D004487 Edema Indomethacin 7.227990266 7907874 8273558 16100529 10653021 8985016 19703484
MESH:D004487 Edema pirinixic acid 7.2212083418
MESH:D004489 Edema, Cardiac Tretinoin 4.6018230668
MESH:D016889 Endometrial Neoplasms Folic Acid 7.9617301261
MESH:D016889 Endometrial Neoplasms Tretinoin 7.9616569247
MESH:D004715 Endometriosis Indomethacin 4.2215652904
MESH:D019446 Endotoxemia Indomethacin 4.6218509659
MESH:D004751 Enteritis Indomethacin 4.8810567023 16328016 17763956
MESH:D020345 Enterocolitis, Necrotizing Indomethacin 5.0917980183
MESH:D004802 Eosinophilia Indomethacin 4.1611298111
MESH:D004938 Esophageal Neoplasms 4,4'-diaminodiphenylmethane 7.413581430
MESH:D004938 Esophageal Neoplasms 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide 7.4120426865
MESH:D004938 Esophageal Neoplasms Indomethacin 7.4111005569
MESH:D017889 Exfoliation Syndrome Folic Acid 5.6116504073
MESH:D005124 Eye Abnormalities Tretinoin 3.649664655 16938888
MESH:D005234 Fatty Liver pirinixic acid 2.8519236843 20131406
MESH:D005334 Fever Indomethacin 4.1910431976 11852909 17627676
MESH:D005350 Fibroma 4,4'-diaminodiphenylmethane 5.156705139
MESH:D005354 Fibrosarcoma Indomethacin 5.0110962813
MESH:D005355 Fibrosis Indomethacin 9.3817994277
MESH:D005355 Fibrosis Tretinoin 9.3817994277
MESH:D005499 Folliculitis Indomethacin 5.3011298111
MESH:D005756 Gastritis Acetaminophen 19.9316983495
MESH:D005756 Gastritis Folic Acid 19.9317171786
MESH:D005756 Gastritis Indomethacin 19.9315046732
MESH:D005901 Glaucoma Folic Acid 5.1716504073
MESH:D005909 Glioblastoma Indomethacin 7.4912870263
MESH:D005909 Glioblastoma Tretinoin 7.4917312396
MESH:D005910 Glioma Indomethacin 3.2516487511 18371953
MESH:D005923 Glomerulosclerosis, Focal Segmental Indomethacin 4.3511849393
MESH:D006042 Goiter 4,4'-diaminodiphenylmethane 4.127505956
MESH:D006073 Gout Indomethacin 5.4711248219
MESH:D006258 Head and Neck Neoplasms Indomethacin 8.1015482327
MESH:D006258 Head and Neck Neoplasms Tretinoin 8.1016096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 5.2916084493
MESH:D006330 Heart Defects, Congenital Folic Acid 7.2116524890 17286298
MESH:D006330 Heart Defects, Congenital Tretinoin 7.2114991402 9664655
MESH:D006333 Heart Failure pirinixic acid 2.5820558911
MESH:D006501 Hepatic Encephalopathy Indomethacin 4.6515633222
MESH:D006505 Hepatitis 4,4'-diaminodiphenylmethane 3.616705139
MESH:D019698 Hepatitis C, Chronic Indomethacin 4.7815135802
MESH:D006529 Hepatomegaly pirinixic acid 3.1019176532 19772884 16221962 18467677
MESH:D006679 HIV Seropositivity Folic Acid 5.6117209195
MESH:D006930 Hyperalgesia Acetaminophen 13.4616870215
MESH:D006930 Hyperalgesia Indomethacin 13.4612727271
MESH:D006930 Hyperalgesia Tretinoin 13.4616870215
MESH:D034321 Hyperamylasemia Indomethacin 5.8517883296
MESH:D006940 Hyperemia Indomethacin 5.1212524144
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.6716778211
MESH:D006943 Hyperglycemia pirinixic acid 3.2620558911
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.5716395265 16397167 16865747 16755160 16433478
MESH:D006949 Hyperlipidemias Indomethacin 4.2517546600
MESH:D006965 Hyperplasia 4,4'-diaminodiphenylmethane 4.0415034207
MESH:D007035 Hypothermia Reserpine 6.361977408
MESH:D007077 Ileal Diseases Indomethacin 5.1610574470 18306037
MESH:D007079 Ileitis Indomethacin 5.4710651667 16133968 10647630
MESH:D007235 Infant, Premature, Diseases Indomethacin 5.5116133044
MESH:D007249 Inflammation Flavonoids 5.5417296493
MESH:D007249 Inflammation Indomethacin 5.543291741 12568917 7812673
MESH:D007333 Insulin Resistance pirinixic acid 2.6816306350
MESH:D007410 Intestinal Diseases Indomethacin 10.2411713966 11855677 17329856 15831440 18236018 15610444 17994277 10210152 11686837
MESH:D007410 Intestinal Diseases Tretinoin 10.2417994277
MESH:D019586 Intracranial Hypertension Indomethacin 5.5115241188
MESH:D007565 Jaundice 4,4'-diaminodiphenylmethane 5.159022650 8074119
MESH:D007569 Jaw Abnormalities Tretinoin 3.9815992940 17551590
MESH:D007579 Jejunal Diseases Indomethacin 5.1616133968 18306037 10574470
MESH:D007674 Kidney Diseases Acetaminophen 6.2915629191 12587719
MESH:D007674 Kidney Diseases Indomethacin 6.2917190690
MESH:D007680 Kidney Neoplasms 4,4'-diaminodiphenylmethane 3.036582329
MESH:D007859 Learning Disorders sevoflurane 4.8719212262
MESH:D016773 Leishmaniasis, Cutaneous Indomethacin 3.9710320625 12228301 11703811
MESH:D007938 Leukemia Tretinoin 2.8117143497
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Indomethacin 3.9815631656 10785260 16572323
MESH:D007951 Leukemia, Myeloid Tretinoin 3.7819285840 16482212 16932348
MESH:D015470 Leukemia, Myeloid, Acute Indomethacin 4.1118360721
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 4.1117596541 19850784 16294345
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 3.2017294898 15748426 17107899 16140955 17339181 16766008 19075265 17712046 17649720 17217047 19642359 17368321 19035177 9834237 16788101 16331271 16823087 17506722 17361223 12679006 19225113 16935935 19029980 16891316 17301526
MESH:D007964 Leukocytosis Indomethacin 5.5116537180
MESH:D007969 Leukomalacia, Periventricular Indomethacin 5.8517980183
MESH:D017880 Limb Deformities, Congenital Tretinoin 3.369224671
MESH:D008101 Liver Abscess, Amebic Indomethacin 5.8511479899
MESH:D008105 Liver Cirrhosis, Biliary 4,4'-diaminodiphenylmethane 3.2415034207 9327722
MESH:D008106 Liver Cirrhosis, Experimental Indomethacin 3.5918194892
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 3.5915474484
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 3.5918397230 16248980
MESH:D008107 Liver Diseases Acetaminophen 4.3119784758 12969438 19014921 16611625 11587558 16610002 12587719 19460945
MESH:D008107 Liver Diseases Folic Acid 4.3116877991
MESH:D017114 Liver Failure, Acute Acetaminophen 3.3117185352 16871587
MESH:D008113 Liver Neoplasms Aflatoxin B1 4.5718177683 15890375 2125692 9163691
MESH:D008113 Liver Neoplasms pirinixic acid 4.5720007298 16377806 15890375
MESH:D008114 Liver Neoplasms, Experimental 4,4'-diaminodiphenylmethane 6.13598648 3712494 1399818 6587162
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 6.138603461
MESH:D008175 Lung Neoplasms Aflatoxin B1 2.7314755239
MESH:D008175 Lung Neoplasms Indomethacin 2.7311053908 11497255 16537180
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.3617718048
MESH:D008325 Mammary Neoplasms, Experimental Reserpine 4.7111921183
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.8116832597
MESH:D008527 Medulloblastoma Tretinoin 2.8117453147
MESH:D008545 Melanoma Tretinoin 1.9516752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.6719513568
MESH:D008569 Memory Disorders sevoflurane 4.8419212262
MESH:D008591 Meningomyelocele Tretinoin 4.5316940565
MESH:D008881 Migraine Disorders Indomethacin 3.7311903285
MESH:D009062 Mouth Neoplasms Indomethacin 4.0512636206
MESH:D009135 Muscular Diseases pirinixic acid 3.6116239165
MESH:D009190 Myelodysplastic Syndromes Tretinoin 3.1217596541
MESH:D009203 Myocardial Infarction pirinixic acid 2.1719151258
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.0116411023
MESH:D009362 Neoplasm Metastasis 4,4'-diaminodiphenylmethane 6.023581430
MESH:D009362 Neoplasm Metastasis Indomethacin 6.0216537180 11053908 11239499
MESH:D009369 Neoplasms pirinixic acid 5.0317405874
MESH:D009369 Neoplasms Tretinoin 5.0316946489 16594593
MESH:D009374 Neoplasms, Experimental Indomethacin 4.2410663608 15625704
MESH:D009421 Nervous System Malformations Tretinoin 3.879125849
MESH:D009436 Neural Tube Defects 4,4'-diaminodiphenylmethane 12.546679447
MESH:D009436 Neural Tube Defects Folic Acid 12.5417438019
MESH:D009436 Neural Tube Defects Tretinoin 12.549142499
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.6318514411
MESH:D019636 Neurodegenerative Diseases Indomethacin 8.6312349958
MESH:D009503 Neutropenia Folic Acid 4.5916322990
MESH:D009765 Obesity pirinixic acid 1.8320558911
MESH:D007752 Obstetric Labor, Premature Indomethacin 5.306374098
MESH:D009784 Occupational Diseases 4,4'-diaminodiphenylmethane 3.506482804 4026338
MESH:D009902 Optic Neuritis 4,4'-diaminodiphenylmethane 5.153988306
MESH:D010003 Osteoarthritis Indomethacin 3.717009135
MESH:D010051 Ovarian Neoplasms Tretinoin 2.3716936753
MESH:D010146 Pain Acetaminophen 11.6716870215
MESH:D010146 Pain Indomethacin 11.6713679232 17627676 3291741 17440234
MESH:D010146 Pain Tretinoin 11.6716870215
MESH:D010149 Pain, Postoperative Indomethacin 4.8112538197 18702446
MESH:D010190 Pancreatic Neoplasms Tretinoin 2.4915976015
MESH:D010195 Pancreatitis Indomethacin 4.0115028970 17883296
MESH:D010212 Papilloma 4,4'-diaminodiphenylmethane 3.597296757
MESH:D010257 Paraneoplastic Syndromes Indomethacin 5.8516537180
MESH:D020734 Parkinsonian Disorders Indomethacin 4.1912349958
MESH:D051302 Paroxysmal Hemicrania Indomethacin 5.8511903285
MESH:D010437 Peptic Ulcer Indomethacin 5.2711148446
MESH:D010518 Periodontitis Indomethacin 5.0517225004
MESH:D010787 Photosensitivity Disorders 4,4'-diaminodiphenylmethane 4.606228378
MESH:D047928 Premature Birth Indomethacin 5.2317000239
MESH:D011471 Prostatic Neoplasms bicalutamide 4.2718487222 19011039 17914592 19240160 15638997
MESH:D011507 Proteinuria Indomethacin 9.6311849393
MESH:D011507 Proteinuria Tretinoin 9.6316636307
MESH:D011625 Pterygium Tretinoin 4.9116723453
MESH:D051437 Renal Insufficiency Folic Acid 4.8815728788
MESH:D015427 Reperfusion Injury pirinixic acid 2.4219058328
MESH:D012162 Retinal Degeneration 4,4'-diaminodiphenylmethane 3.433692021
MESH:D012208 Rhabdomyosarcoma Tretinoin 4.1916283617 16116481
MESH:D012559 Schizophrenia Folic Acid 2.9016641680
MESH:D012871 Skin Diseases Folic Acid 3.2718709164
MESH:D012878 Skin Neoplasms Tretinoin 2.6416467112
MESH:D013118 Spinal Cord Diseases Folic Acid 5.6116361298
MESH:D013272 Stomach Diseases Indomethacin 4.5317638125 10486359 17207306 10215738 10192188 15038085 16184426 18209964 15472012 17160473 16113693 18545984 16280098
MESH:D013274 Stomach Neoplasms Folic Acid 3.6017171786
MESH:D013274 Stomach Neoplasms Indomethacin 3.6015609394
MESH:D013274 Stomach Neoplasms Tretinoin 3.6017261132
MESH:D013276 Stomach Ulcer Indomethacin 3.6618237397 18181030 11595431 18209962 16934674 17895592 15255614 1323529 11523592 12787963 16169175 17654042 18193104 18726076 11145282 17918041 12500499 10423059 16252198 10878458 17657623 17627676 11729361 17135157 16150113 12467913 16755016 12498302 11906479 15138204 18543354 18299717 17977527 11595415 18431645 15104355 10750652 16397915 12077510 18087811 14567935 16631530
MESH:D020521 Stroke Folic Acid 4.3916517955
MESH:D013964 Thyroid Neoplasms 4,4'-diaminodiphenylmethane 12.406587162 1399818 7505956 3712494 6582329
MESH:D013964 Thyroid Neoplasms Indomethacin 12.4014736730 18791128 11352223
MESH:D013964 Thyroid Neoplasms Tretinoin 12.4016026305 17045167
MESH:D014062 Tongue Neoplasms Tretinoin 3.8616051514
MESH:D014376 Tuberculosis Tretinoin 3.2716040207
MESH:D014456 Ulcer Indomethacin 5.0117380554 10574470
MESH:D001749 Urinary Bladder Neoplasms 4,4'-diaminodiphenylmethane 2.308074119
MESH:D014581 Urticaria Acetaminophen 3.0610982225
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 3.7516129372
MESH:D014604 Uveal Neoplasms Tretinoin 4.7416752155
MESH:D014820 Vitiligo Tretinoin 4.1516761959
MESH:D014839 Vomiting Indomethacin 4.8811897121
MESH:D009396 Wilms Tumor Tretinoin 4.0416287080
Pathway ID Pathway Name
KEGG:00330 Arginine and proline metabolism
KEGG:00270 Cysteine and methionine metabolism
KEGG:01100 Metabolic pathways
REACT:13 Metabolism of amino acids and derivatives
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA24763
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    Releated drug ID Related drug Name
    PA450423l-methionine
    Drug Bank Top
    Drugbank ID Action Drug Name Description
    DB00118 - S-Adenosylmethionine Dietary supplement;Micronutrient
    DB01917 - Putrescine
    DB03375 - Hydroxyalanine
    DB03754 - Tris(Hydroxymethyl)Aminomethane Buffers;Excipients
    DB08163 - 5'-{[4-(aminooxy)butyl](methyl)amino}-5'-deoxy-8-ethenyladenosine
    No data
    No data
    No data

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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