AutismKB 2.0

Annotation Detail for GATA4


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Basic Information Top
Gene Symbol:GATA4 ( MGC126629 )
Gene Full Name: GATA binding protein 4
Band: 8p23.1
Quick LinksEntrez ID:2626; OMIM: 600576; Uniprot ID:GATA4_HUMAN; ENSEMBL ID: ENSG00000136574; HGNC ID: 4173
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
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Pathway IDPathway Name
200196Notch-mediated HES/HEY network
No data
No data
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1934Cancer
1940Ovarian disease
1975Congenital heart disease
Desease Name
CHEMDEPENDENCY
alcohol dependence
No data
Desease Name
Atrial septal defect-2
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of GATA4 mRNAaffects expression 21346803
C021296 2-ethoxyethanol 2-ethoxyethanol results in increased expression of GATA4 mRNAincreases expression 19643169
D000082 Acetaminophen Acetaminophen affects the expression of GATA4 mRNAaffects expression 17562736
D000450 Aldosterone Aldosterone results in increased expression of GATA4 proteinincreases expression 19966502
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GATA4 mRNAaffects expression 16483693
D017638 Asbestos, Crocidolite Asbestos, Crocidolite affects the expression of GATA4 mRNAaffects expression 17331233
D001374 Azacitidine Azacitidine results in increased expression of GATA4 mRNAincreases expression 18037191
D001374 Azacitidine Azacitidine results in increased expression of GATA4 proteinincreases expression 18037191
C086232 bosentan bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 mRNA]decreases expression|decreases reaction 17974986
C086232 bosentan bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]decreases expression|decreases reaction 17974986
D002248 Carbon Monoxide Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased activity of GATA4 protein]decreases activity|decreases reaction 18037988
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GATA4 mRNAaffects expression 17484886
D004317 Doxorubicin bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 mRNA]decreases expression|decreases reaction 17974986
D004317 Doxorubicin bosentan inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]decreases expression|decreases reaction 17974986
D004317 Doxorubicin Carbon Monoxide inhibits the reaction [Doxorubicin results in decreased activity of GATA4 protein]decreases activity|decreases reaction 18037988
D004317 Doxorubicin CSF3 protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]decreases expression|decreases reaction 17334414
D004317 Doxorubicin Doxorubicin results in decreased activity of GATA4 proteindecreases activity 18037988
D004317 Doxorubicin Doxorubicin results in decreased expression of GATA4 mRNAdecreases expression 17974986
D004317 Doxorubicin Doxorubicin results in decreased expression of GATA4 proteindecreases expression 16109756
18083897
17334414
16449733
17974986
D004317 Doxorubicin EPO protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]decreases expression|decreases reaction 16449733
D004317 Doxorubicin HGF protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]decreases expression|decreases reaction 16109756
18083897
D004317 Doxorubicin PD 98059 inhibits the reaction [HGF protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]]decreases expression|decreases reaction 18083897
16109756
D004317 Doxorubicin Doxorubicin results in decreased expression of GATA4 proteindecreases expression 15767673
D000431 Ethanol ALDH2 protein inhibits the reaction [Ethanol results in increased phosphorylation of GATA4 protein]decreases reaction|increases phosphorylation 19332462
D000431 Ethanol Ethanol results in increased phosphorylation of GATA4 proteinincreases phosphorylation 18377926
19332462
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GATA4 mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GATA4 mRNAaffects cotreatment|increases expression 17942748
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of GATA4 mRNAdecreases expression 12655037
C056599 icariin icariin results in increased expression of GATA4 mRNAincreases expression 16490167
D007545 Isoproterenol [Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNAaffects cotreatment|increases expression 10710348
C037068 latrunculin B latrunculin B inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 11739382
C005219 methyl cellosolve methyl cellosolve results in increased expression of GATA4 mRNAincreases expression 19643169
C091888 monoisoamyl-2,3-dimercaptosuccinate monoisoamyl-2,3-dimercaptosuccinate results in decreased expression of GATA4 mRNAdecreases expression 19615344
C091888 monoisoamyl-2,3-dimercaptosuccinate [sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of GATA4 mRNAaffects cotreatment|decreases expression 19615344
C007350 nitrofen nitrofen results in decreased expression of GATA4 mRNAdecreases expression 18280291
C093973 PD 98059 PD 98059 inhibits the reaction [EDN1 protein results in increased phosphorylation of GATA4 protein]decreases reaction|increases phosphorylation 11583584
C093973 PD 98059 PD 98059 inhibits the reaction [HGF protein inhibits the reaction [Doxorubicin results in decreased expression of GATA4 protein]]decreases expression|decreases reaction 16109756
18083897
C093973 PD 98059 PD 98059 inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 10788492
C093973 PD 98059 PD 98059 inhibits the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]decreases reaction|increases phosphorylation 10788492
C076994 perfluorooctane sulfonic acid perfluorooctane sulfonic acid results in decreased expression of GATA4 mRNAdecreases expression 16221955
D010656 Phenylephrine EP300 protein promotes the reaction [[Phenylephrine results in increased activity of GATA4 protein] which results in increased expression of EDN1 mRNA]increases activity|increases expression|increases reaction 12724418
D010656 Phenylephrine [Phenylephrine co-treated with Isoproterenol] results in increased expression of GATA4 mRNAaffects cotreatment|increases expression 10710348
D010656 Phenylephrine GATA4 protein affects the susceptibility to Phenylephrineaffects response to substance 18252717
D010656 Phenylephrine latrunculin B inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 11739382
D010656 Phenylephrine MAPK1 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]affects reaction|increases phosphorylation 10788492
D010656 Phenylephrine MAPK3 protein affects the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]affects reaction|increases phosphorylation 10788492
D010656 Phenylephrine PD 98059 inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 10788492
D010656 Phenylephrine PD 98059 inhibits the reaction [Phenylephrine results in increased phosphorylation of GATA4 protein]decreases reaction|increases phosphorylation 10788492
D010656 Phenylephrine Phenylephrine promotes the reaction [GATA4 protein binds to EDN1 promoter]affects binding|increases reaction 10788492
D010656 Phenylephrine Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]affects binding|increases reaction 15220332
D010656 Phenylephrine Phenylephrine results in increased acetylation of GATA4 proteinincreases acetylation 12724418
D010656 Phenylephrine Phenylephrine results in increased activity of GATA4 proteinincreases activity 12724418
15220332
11739382
D010656 Phenylephrine Phenylephrine results in increased expression of GATA4 proteinincreases expression 12724418
19966502
D010656 Phenylephrine Phenylephrine results in increased phosphorylation of and results in increased activity of GATA4 proteinincreases activity|increases phosphorylation 10788492
D010656 Phenylephrine Y 27632 inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 11739382
D010656 Phenylephrine ZFPM2 protein inhibits the reaction [Phenylephrine promotes the reaction [GATA4 protein binds to EP300 protein]]affects binding|decreases reaction|increases reaction 15220332
D010656 Phenylephrine ZFPM2 protein inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 15220332
C006253 pirinixic acid pirinixic acid results in decreased expression of GATA4 mRNAdecreases expression 20059764
C006253 pirinixic acid pirinixic acid results in increased expression of GATA4 mRNAincreases expression 17951219
C006253 pirinixic acid PPARA protein promotes the reaction [pirinixic acid results in decreased expression of GATA4 mRNA]decreases expression|increases reaction 20059764
D015237 Dinoprost Dinoprost promotes the reaction [GATA4 protein binds to CYP19A1 promoter]affects binding|increases reaction 15271885
D015237 Dinoprost Dinoprost results in increased activity of GATA4 proteinincreases activity 15271885
C017947 sodium arsenite [sodium arsenite co-treated with monoisoamyl-2,3-dimercaptosuccinate] results in decreased expression of GATA4 mRNAaffects cotreatment|decreases expression 19615344
C017947 sodium arsenite sodium arsenite results in decreased expression of GATA4 mRNAdecreases expression 19615344
C105686 SU 5402 SU 5402 affects the expression of GATA4 mRNAaffects expression 15298682
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GATA4 mRNAaffects cotreatment|increases expression 17942748
D013755 Tetradecanoylphorbol Acetate Tetradecanoylphorbol Acetate results in increased phosphorylation of GATA4 proteinincreases phosphorylation 11583584
D014212 Tretinoin Tretinoin results in increased expression of GATA4 mRNAincreases expression 16619266
16604517
16236135
D014212 Tretinoin Tretinoin affects the expression of GATA4 mRNAaffects expression 16423341
D014810 Vitamin E Vitamin E affects the expression of GATA4 mRNAaffects expression 15370891
C108830 Y 27632 Y 27632 inhibits the reaction [Phenylephrine results in increased activity of GATA4 protein]decreases reaction|increases activity 11739382
D015032 Zinc Zinc results in decreased expression of GATA4 mRNAdecreases expression 17074742
D019287 Zinc Sulfate Zinc Sulfate results in decreased expression of GATA4 mRNAdecreases expression 17074742
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced 2-ethoxyethanol 17.796499796 7151721 6499812 6499823 6499820
MESH:D000014 Abnormalities, Drug-Induced Ethanol 17.7918926900 17676605
MESH:D000014 Abnormalities, Drug-Induced methyl cellosolve 17.793652986 6499812 6474471
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 17.7915322242 14514962 11752688
MESH:D000138 Acidosis Ammonium Chloride 15.9618287403
MESH:D000138 Acidosis Ethanol 15.9611192467
MESH:D000138 Acidosis Zinc Sulfate 15.967265320
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.6117505938
MESH:D000169 Acrodermatitis Zinc 5.0816889938 17190629 17202136
MESH:D055371 Acute Lung Injury pirinixic acid 2.8218653653
MESH:D000230 Adenocarcinoma Doxorubicin 4.1017418594
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.1014692618
MESH:D018248 Adenoma, Liver Cell pirinixic acid 8.8216434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 8.8216835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.3715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.5716712894 17306315
MESH:D000419 Albuminuria Doxorubicin 4.2321441931
MESH:D020268 Alcohol-Induced Disorders, Nervous System Ethanol 4.9915451039 15451040
MESH:D000505 Alopecia Tretinoin 3.3615955085
MESH:D000544 Alzheimer Disease icariin 4.6719782061 19858766
MESH:D000544 Alzheimer Disease Zinc 4.6716325427 16410023 16580781 17119284
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.6711748828
MESH:D000748 Anemia, Macrocytic methyl cellosolve 6.023699323
MESH:D000755 Anemia, Sickle Cell Zinc 4.5916916123
MESH:D000799 Angioedema Acetaminophen 3.5110982225
MESH:D000853 Anophthalmos Ethanol 4.5015513904
MESH:D000860 Anoxia Zinc Sulfate 4.697265320
MESH:D001008 Anxiety Disorders Ethanol 3.7511141031
MESH:D001145 Arrhythmias, Cardiac Phenylephrine 3.8317460149
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.1511256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 6.5415885639
MESH:D001169 Arthritis, Experimental Tretinoin 6.5416412693
MESH:D001172 Arthritis, Rheumatoid Tretinoin 2.1916292516
MESH:D053627 Asthenozoospermia 2-ethoxyethanol 11.526499823 6499807 10689203
MESH:D053627 Asthenozoospermia methyl cellosolve 11.523987992
MESH:D001249 Asthma Tretinoin 4.7116456186
MESH:D001249 Asthma Zinc 4.7117085522
MESH:D001259 Ataxia 2-ethoxyethanol 5.157151721
MESH:C538263 Atrial septal defect 2 marker/mechanism
MESH:D001284 Atrophy 2-ethoxyethanol 10.386499799 15850284
MESH:D001284 Atrophy methyl cellosolve 10.382626667 6705890 3699323
MESH:D001321 Autistic Disorder Acetaminophen 1.4518445737
MESH:D053713 Azoospermia 2-ethoxyethanol 5.266492198 6499807
MESH:D001471 Barrett Esophagus Tretinoin 4.0916935849
MESH:D001724 Birth Weight 2-ethoxyethanol 6.182884743 6499823
MESH:D001778 Blood Coagulation Disorders pirinixic acid 13.5919483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 13.5912125929
MESH:D001778 Blood Coagulation Disorders Tretinoin 13.5916206674 16197459
MESH:D001836 Body Weight Changes 2-ethoxyethanol 10.927151721 6499796
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 10.9215340226
MESH:D001847 Bone Diseases icariin 6.0818295595
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.5615746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.3714601052
MESH:D001919 Bradycardia Isoproterenol 9.876740701
MESH:D001919 Bradycardia Phenylephrine 9.8715306635
MESH:D001930 Brain Injuries Zinc 4.3717109824
MESH:D002545 Brain Ischemia icariin 5.1519303870
MESH:D001932 Brain Neoplasms Doxorubicin 3.5317150277
MESH:D001943 Breast Neoplasms Doxorubicin 1.8917369602 18695136 15567936 16264153 15994142 15939500 16935488 16595493 18382427 19526202 15634643 18628466 16115903 15136595 17983394 16096432 15692762 18234424 11325840 15668708 17426702 15993339 16322301 16826403
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8920435547
MESH:D001943 Breast Neoplasms Tretinoin 1.8916443354 16873071 16166294
MESH:D001997 Bronchopulmonary Dysplasia Tretinoin 4.2616813970
MESH:D002056 Burns Ethanol 4.3316374292
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 8.8816227642 16050911 15721981 18705752 15700767 3786805 15673190 16124888 10355542 16011737 16192424 16097048
MESH:D002252 Carbon Tetrachloride Poisoning Vitamin E 8.8816050911
MESH:D002276 Carcinoid Tumor Doxorubicin 4.4816051944
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.5516835633
MESH:D018236 Carcinoma, Embryonal Tretinoin 4.8316168501
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 13.1816705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 13.183084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 13.1818788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 13.1816234567 18059187 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Ethanol 13.1815763234 15289165 18788625
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 13.1817306315 16507464 15276417
MESH:D006528 Carcinoma, Hepatocellular Tretinoin 13.181917145
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 3.0116201981 1485588
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 13.276189445
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 13.2718572023
MESH:D002294 Carcinoma, Squamous Cell Tetradecanoylphorbol Acetate 13.2718922899
MESH:D002294 Carcinoma, Squamous Cell Tretinoin 13.2716096774 16051514
MESH:D002294 Carcinoma, Squamous Cell Zinc 13.2716543248
MESH:D006332 Cardiomegaly marker/mechanism 18252717
MESH:D006332 Cardiomegaly Ethanol 14.9019332462
MESH:D006332 Cardiomegaly Isoproterenol 14.9011179087 7544033
MESH:D006332 Cardiomegaly Phenylephrine 14.9015728586 11179087 17124262 17287366 11754973 16170337
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 14.9018850075 16120746 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.3216651473 16242529 15811867 17382496 16952015 15792986 16278810 17519947 18627295 16612575 16109756 16455267 16269455 17928571 15505089 17924179 17351982 17007740 16364871 15476868 16731534 17974986 17131338 17308081 17329180
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 2.8316243910 17334414
MESH:D002318 Cardiovascular Diseases Aldosterone 7.3611230374
MESH:D002318 Cardiovascular Diseases Zinc 7.3616936243
MESH:D002386 Cataract Acetaminophen 6.5910977129
MESH:D002386 Cataract Tretinoin 6.5917460283
MESH:D002471 Cell Transformation, Neoplastic Dinoprost 6.7716192471
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 6.7719524636 20056578
MESH:D018290 Cervical Intraepithelial Neoplasia Tretinoin 4.2616129372
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 2.8916835633
MESH:D002764 Cholecystitis 2-ethoxyethanol 12.556499794
MESH:D002764 Cholecystitis methyl cellosolve 12.556499794
MESH:D002779 Cholestasis Ethinyl Estradiol 6.9517681005 11677210 16105132 17110522 16919318 15861022 17333356
MESH:D002779 Cholestasis pirinixic acid 6.9519176532
MESH:D002822 Choriocarcinoma Tretinoin 4.8316461808
MESH:D002971 Cleft Lip Ethanol 3.4115513904
MESH:D002972 Cleft Palate Ethanol 9.0215513904
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 9.0215668235 8697196 16354765 12621046 15340226
MESH:D002972 Cleft Palate Tretinoin 9.029407595
MESH:D003092 Colitis Carbon Monoxide 9.1216365149
MESH:D003092 Colitis Tretinoin 9.1217035595
MESH:D015179 Colorectal Neoplasms marker/mechanism 19509152
MESH:D015179 Colorectal Neoplasms Azacitidine 2.8319934284
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.8318259882 18802399
MESH:D000013 Congenital Abnormalities methyl cellosolve 8.526499821 12530607
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 8.5214669216 17141729
MESH:D003384 Coxsackievirus Infections bosentan 6.2720392896
MESH:D019465 Craniofacial Abnormalities Ethanol 8.9519302082 15513904 15451039 10194807 11198716 15451040 11873399
MESH:D019465 Craniofacial Abnormalities nitrofen 8.9511405365
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 8.9510048152 20055451 15322242
MESH:D019465 Craniofacial Abnormalities Tretinoin 8.958800419 17551590 9142499 10589399 9125849 16925845 9211117 14991402 9224671 9664655
MESH:D019465 Craniofacial Abnormalities Vitamin E 8.9519769572
MESH:D019465 Craniofacial Abnormalities Zinc 8.9519302082
MESH:D003490 Cyanosis 2,4-dinitrotoluene 3.7018551238
MESH:D003643 Death 2-ethoxyethanol 5.636499796
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.2718249437
MESH:D003920 Diabetes Mellitus Zinc 3.9316479319
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.5917107852
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 13.9021346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 13.9012958197 14550746 19739265 17906064 12705907 18071297 17522070 11287661 19085960 10915739 11421492 18713872 11461765 19370779 19416960 19164858 14725611 16393943 16177239 12594235 16781746 19923254 15968718 17562736 11834606 2444490 16109766 16081117 16227642 11529661 14986274 16485898 15619225 11743745 10663392 19420014 12540782 12392966 10774834 12153990 11739529
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 13.9021278145 7179309 4309450 15998439 9327722 11566570 2869522 15027814 15968718 10092053 19085960 19336974 16177239 3786805 10915739 6884620 17522070 3732212 6623471 7120509 7440962 16227642
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 13.9017416283
MESH:D056486 Drug-Induced Liver Injury Ethanol 13.9011566570
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 13.9020420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.7719426721
MESH:D004362 Drug Toxicity Doxorubicin 7.3218602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.3211462148
MESH:C538011 Eales disease Vitamin E 4.379068938
MESH:D004487 Edema pirinixic acid 9.8012083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 9.8011000095 12711302
MESH:D004487 Edema Tetradecanoylphorbol Acetate 9.808113982 15177302 8273558 16716910 9599246 11698051 7812673
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 10.8415322242 16714409 18230668
MESH:D004489 Edema, Cardiac Tretinoin 10.8418230668
MESH:D020964 Embryo Loss 2-ethoxyethanol 6.186499796
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 2.8812538720
MESH:D016889 Endometrial Neoplasms Doxorubicin 6.8817359293
MESH:D016889 Endometrial Neoplasms Tretinoin 6.8816569247
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.7410568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 4.8318037988
MESH:D007172 Erectile Dysfunction icariin 5.1216281085 15329286
MESH:D004938 Esophageal Neoplasms Ethanol 4.6116704527
MESH:D004938 Esophageal Neoplasms Zinc 4.6116543248
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 8.0411564622
MESH:D005124 Eye Abnormalities Tretinoin 8.049664655 16938888
MESH:D005234 Fatty Liver Carbon Tetrachloride 16.3915959796 17595544 12795759 16045604 12631006 19224547 61145 16239168
MESH:D005234 Fatty Liver Ethanol 16.3918620774 16409862 19236843
MESH:D005234 Fatty Liver Ethinyl Estradiol 16.3915345470
MESH:D005234 Fatty Liver pirinixic acid 16.3920131406 19236843
MESH:D005235 Fatty Liver, Alcoholic Ethanol 5.3317920746
MESH:D005310 Fetal Alcohol Syndrome Ethanol 4.9716946407 15451040 10194807 15513904
MESH:D005313 Fetal Death 2-ethoxyethanol 9.782884743 7151721 6499823 7198755 6499820
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 9.7811858732
MESH:D005317 Fetal Growth Retardation 2-ethoxyethanol 5.106499796
MESH:D005327 Fetal Resorption 2-ethoxyethanol 11.576499820 6499812
MESH:D005327 Fetal Resorption methyl cellosolve 11.576474471 6499812 6499821 3987992
MESH:D020567 Fetal Weight 2-ethoxyethanol 12.557151721 2884743 6499820
MESH:D020567 Fetal Weight methyl cellosolve 12.556474471 6499812 6499821
MESH:D005334 Fever Dinoprost 5.2411852909
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.2619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 12.9218705752
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 12.9220067830
MESH:D005355 Fibrosis Tretinoin 12.9217994277
MESH:D005532 Foot Deformities, Congenital methyl cellosolve 5.173652986
MESH:D005756 Gastritis Acetaminophen 17.1416983495
MESH:D005756 Gastritis Ethanol 17.1415046732
MESH:D005756 Gastritis Zinc 17.1417241300
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.3516452187
MESH:D005909 Glioblastoma Doxorubicin 10.8417150277
MESH:D005909 Glioblastoma perfluorooctane sulfonic acid 10.8417162496
MESH:D005909 Glioblastoma Tretinoin 10.8417312396
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.2610696789
MESH:D006130 Growth Disorders Zinc 3.7517217573
MESH:D006258 Head and Neck Neoplasms Doxorubicin 7.1215692506
MESH:D006258 Head and Neck Neoplasms Tretinoin 7.1216096774
MESH:D006317 Hearing Loss, Noise-Induced Tretinoin 4.8316084493
MESH:D006330 Heart Defects, Congenital nitrofen 14.6116080930
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 14.6111294989 10048152
MESH:D006330 Heart Defects, Congenital Tretinoin 14.6114991402 9664655
MESH:D006330 Heart Defects, Congenital Vitamin E 14.6116080930
MESH:D006331 Heart Diseases Doxorubicin 3.2616244372 17888722 16495754 16144979 18006777 16330681 17875725 16244371 16879835 16707910 14766674 18674790 12587719
MESH:D006333 Heart Failure Doxorubicin 15.3017481944
MESH:D006333 Heart Failure Isoproterenol 15.3018097624
MESH:D006333 Heart Failure pirinixic acid 15.3020558911
MESH:D006333 Heart Failure Zinc 15.3017162251
MESH:D006335 Heart Injuries Zinc 5.4417074742
MESH:D006345 Heart Septal Defects, Ventricular methyl cellosolve 5.456499821
MESH:D016481 Helicobacter Infections Zinc 4.2317241300
MESH:D006394 Hemangiosarcoma Doxorubicin 3.6115692506
MESH:D006402 Hematologic Diseases 2-ethoxyethanol 5.0920172899 10514026
MESH:D006461 Hemolysis 2-ethoxyethanol 11.2419051582 17874071
MESH:D006461 Hemolysis methyl cellosolve 11.2417874071
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.0511000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.2919900420 19110552
MESH:D006527 Hepatolenticular Degeneration Zinc 10.2617276780
MESH:D006527 Hepatolenticular Degeneration Zinc Sulfate 10.2617063115
MESH:D006529 Hepatomegaly pirinixic acid 7.2119772884 16221962 18467677 19176532
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 7.2116120746 15340226 12621046
MESH:D006548 Hernia, Diaphragmatic marker/mechanism 18280291
MESH:D006548 Hernia, Diaphragmatic nitrofen 5.9018280292 16863852 12904592 16292651 10898224 17270546 9698600 15707848 18958481 11685700 12505043 9473106 11057544 10646786 9859898 16473863 15578192 16080930 15756563 11588001 15185205 12547725 10370016 10370017 12407540 17618886 15136996 10541330 12194112 9575882 16720372 11051153 11409163 10898222 11329586 10359170 7760232 7576705 8863223 15764645 7520565 12746050 10693666 9476886 12021965 15793718 16490937 11076806 11584395 18280291 12759764 15088113 17245593
MESH:D006548 Hernia, Diaphragmatic Vitamin E 5.9016863852 16490937
MESH:D006689 Hodgkin Disease Doxorubicin 6.5818501091 15147373 17606976
MESH:D006689 Hodgkin Disease sodium arsenite 6.5812676792
MESH:D019584 Hot Flashes Vitamin E 3.6414716179
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.7115340226 8697196 18606429 16354765 16959395
MESH:D006930 Hyperalgesia Acetaminophen 11.6016870215
MESH:D006930 Hyperalgesia Ethanol 11.6018783367
MESH:D006930 Hyperalgesia Tretinoin 11.6016870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.2116899240
MESH:D017681 Hypereosinophilic Syndrome Tretinoin 4.2516778211
MESH:D006943 Hyperglycemia pirinixic acid 2.9020558911
MESH:D006973 Hypertension Phenylephrine 4.888949925 12717712
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8818670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 3.7715338365
MESH:D006976 Hypertension, Pulmonary bosentan 5.0216219361
MESH:D006984 Hypertrophy Isoproterenol 10.0312791704
MESH:D006984 Hypertrophy Phenylephrine 10.0318502941 12791704
MESH:D007021 Hypospadias Ethinyl Estradiol 3.4916569931 16945680
MESH:D007022 Hypotension Isoproterenol 8.766740701
MESH:D007022 Hypotension Zinc Sulfate 8.767265320
MESH:D007247 Infertility, Female 2-ethoxyethanol 9.406499823
MESH:D007247 Infertility, Female Ethinyl Estradiol 9.4012013081
MESH:D007248 Infertility, Male 2-ethoxyethanol 14.376499823
MESH:D007248 Infertility, Male Ethinyl Estradiol 14.3717937319
MESH:D007248 Infertility, Male methyl cellosolve 14.373987992
MESH:D007248 Infertility, Male sodium arsenite 14.3712646999 15346721
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.5912200463 12878042
MESH:D007249 Inflammation Tetradecanoylphorbol Acetate 4.5915177302 7812673 7562506 8273558 11698051
MESH:D007251 Influenza, Human Vitamin E 3.8816624496
MESH:D007333 Insulin Resistance pirinixic acid 2.4216306350
MESH:D007410 Intestinal Diseases Tretinoin 3.4517994277
MESH:D007511 Ischemia Zinc 4.3116584753
MESH:D007569 Jaw Abnormalities Ethanol 15.5015513904
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 15.5016580747
MESH:D007569 Jaw Abnormalities Tretinoin 15.5017551590 15992940
MESH:D007674 Kidney Diseases Acetaminophen 17.0615629191 12587719
MESH:D007674 Kidney Diseases Doxorubicin 17.0615369732 15699352 16775033
MESH:D007674 Kidney Diseases sodium arsenite 17.0620008137
MESH:D007674 Kidney Diseases Vitamin E 17.0612488133
MESH:D007674 Kidney Diseases Zinc 17.0616960431
MESH:D007676 Kidney Failure, Chronic Doxorubicin 9.2116707910
MESH:D007676 Kidney Failure, Chronic Zinc 9.2116518626
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 2.7216705839
MESH:D007859 Learning Disorders Ethanol 9.1915451040
MESH:D007859 Learning Disorders icariin 9.1919782061
MESH:D016773 Leishmaniasis, Cutaneous Zinc Sulfate 4.0015237267
MESH:D007938 Leukemia Azacitidine 6.1119148494
MESH:D007938 Leukemia Tretinoin 6.1117143497
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 4.8316085563
MESH:D007948 Leukemia, Monocytic, Acute PD 98059 4.9016972261
MESH:D007951 Leukemia, Myeloid Azacitidine 8.8319077051
MESH:D007951 Leukemia, Myeloid Tretinoin 8.8316932348 16482212 19285840
MESH:D015470 Leukemia, Myeloid, Acute Azacitidine 3.9817596541 18720364
MESH:D015470 Leukemia, Myeloid, Acute Tretinoin 3.9819850784 16294345 17596541
MESH:D054429 Leukemia, Myelomonocytic, Juvenile Azacitidine 4.8919299654
MESH:D015473 Leukemia, Promyelocytic, Acute Tretinoin 2.9419225113 16823087 19029980 16788101 16140955 17294898 17217047 12679006 17301526 19075265 15748426 17649720 17368321 19035177 17506722 17107899 17339181 17712046 16766008 17361223 16935935 19642359 16331271 9834237 16891316
MESH:D017880 Limb Deformities, Congenital Ethanol 12.5117676605
MESH:D017880 Limb Deformities, Congenital methyl cellosolve 12.516499821
MESH:D017880 Limb Deformities, Congenital Tretinoin 12.519224671
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.2116943688 17174718 11408273 11903743 16221502 16239168 17157831 17334410 21278145
MESH:D008103 Liver Cirrhosis Ethanol 6.2115289165
MESH:D008104 Liver Cirrhosis, Alcoholic Ethanol 4.7718295389
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 12.4512546737 10355542 18277467 17721639 14512876 18481824 12445418 17631135 17944888 15052691 17557913 11481614 18054572 14724832 15338365 18166357 18317297 12632512 15818738 16192424 15925388 15876570 18006644 16097048 15673190 12445421 17805973 17640975 16116963 17525996 16638106 13678700 17565644 12667390 18412020 18205269 14620537 18418968 18705752 20821823 17698563 18187930 14748882 18420326 15057751 15650968 16015684 16033810 14716496 18395095 18210741 12609069 15730626 18156304 17708605 17976157 16248980 16011737 17481882 15893842 17823541 12958196 15931870 17900296 12389079 17766677 12666154 18263696 16136751 14716833 18472332 15959796 12632514 15123356 12649538 18376398 17761835 18429990 12898905 16027843 17869086 18339082 18472094 12586293 15370692 18251166 18395914 15362042 17922224 12741479 17714472 18279442 15996030
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 12.4516595196 16439617
MESH:D008106 Liver Cirrhosis, Experimental Ethanol 12.4518166357
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 12.4515474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 12.4512878042
MESH:D008106 Liver Cirrhosis, Experimental Tretinoin 12.4518397230 16248980
MESH:D008106 Liver Cirrhosis, Experimental Vitamin E 12.4516169303
MESH:D008106 Liver Cirrhosis, Experimental Y 27632 12.4513678700
MESH:D008107 Liver Diseases Acetaminophen 6.2019460945 16610002 19014921 16611625 12969438 12587719 19784758 11587558
MESH:D008107 Liver Diseases Carbon Monoxide 6.2017173083
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.2016964402 17285989 15720792 15830285 16246199
MESH:D008108 Liver Diseases, Alcoholic Ethanol 4.3317347304 17207112
MESH:D017093 Liver Failure Carbon Tetrachloride 3.8515123358
MESH:D017114 Liver Failure, Acute Acetaminophen 8.4717185352 16871587
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 8.4714706259 16899240
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 9.6119294768
MESH:D008113 Liver Neoplasms pirinixic acid 9.6116377806 20007298 15890375
MESH:D008113 Liver Neoplasms sodium arsenite 9.6116712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 9.6116984957
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 8.6712014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 8.6717085340 16842330
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 8.6712151625
MESH:D008171 Lung Diseases nitrofen 11.2417245593 9859898 9614859 16863852
MESH:D008171 Lung Diseases sodium arsenite 11.2419095001
MESH:D008171 Lung Diseases Vitamin E 11.2416863852
MESH:D055370 Lung Injury Asbestos, Crocidolite 3.7117365036
MESH:D008175 Lung Neoplasms Azacitidine 7.9821224363
MESH:D008175 Lung Neoplasms Doxorubicin 7.9817418594 6189445
MESH:D008175 Lung Neoplasms sodium arsenite 7.9816712894 15276417 17306315 19931552 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 7.9811884234 19555203
MESH:D008175 Lung Neoplasms Tetradecanoylphorbol Acetate 7.9811807781
MESH:D008175 Lung Neoplasms Vitamin E 7.9811062179
MESH:D008223 Lymphoma Doxorubicin 3.2316098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.5317654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.2515621674
MESH:D008231 Lymphopenia methyl cellosolve 5.453699323
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 8.9815458769
MESH:D008325 Mammary Neoplasms, Experimental Tetradecanoylphorbol Acetate 8.988985016
MESH:D008325 Mammary Neoplasms, Experimental Zinc 8.9812773700
MESH:D008527 Medulloblastoma Tretinoin 2.6517453147
MESH:D008545 Melanoma Doxorubicin 4.7816827129
MESH:D008545 Melanoma sodium arsenite 4.7816487513 19082730
MESH:D008545 Melanoma Tretinoin 4.7816752155
MESH:D008546 Melanoma, Experimental Acetaminophen 3.2519513568
MESH:D008569 Memory Disorders Ethanol 9.1518411066 15451040
MESH:D008569 Memory Disorders icariin 9.1519782061
MESH:D008591 Meningomyelocele Tretinoin 4.1116940565
MESH:D008654 Mesothelioma Asbestos, Crocidolite 5.9918303189 16966607 16166281
MESH:D008654 Mesothelioma Doxorubicin 5.9917638057
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.2115792986
MESH:D009006 Monosomy Azacitidine 5.7519299654
MESH:D052016 Mucositis Doxorubicin 4.4617415656
MESH:D009101 Multiple Myeloma Azacitidine 3.7418443271 19549372
MESH:D009135 Muscular Diseases pirinixic acid 3.1916239165
MESH:D009190 Myelodysplastic Syndromes Azacitidine 7.0819805378 17611569 18720364 17596541
MESH:D009190 Myelodysplastic Syndromes Tretinoin 7.0817596541
MESH:D009203 Myocardial Infarction Doxorubicin 8.8019429709 15857846
MESH:D009203 Myocardial Infarction Isoproterenol 8.8016697266 19172585 17052832 15740881 16538859 16584858 19595682
MESH:D009203 Myocardial Infarction pirinixic acid 8.8019151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.7612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.7016411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 9.8118551238
MESH:D009336 Necrosis 2-ethoxyethanol 9.8120172899
MESH:D009362 Neoplasm Metastasis Doxorubicin 2.8218259882
MESH:D009369 Neoplasms pirinixic acid 7.2817405874
MESH:D009369 Neoplasms sodium arsenite 7.2811559025
MESH:D009369 Neoplasms Tretinoin 7.2816946489 16594593
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.3520056578
MESH:D009401 Nephrosis Doxorubicin 4.4516636307 16899518
MESH:D009404 Nephrotic Syndrome Doxorubicin 3.7316889571 15640375
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.4814600291
MESH:D009421 Nervous System Malformations Tretinoin 8.489125849
MESH:D009436 Neural Tube Defects sodium arsenite 6.6112854658
MESH:D009436 Neural Tube Defects Tretinoin 6.619142499
MESH:D009447 Neuroblastoma Doxorubicin 3.0915555623
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.6118514411
MESH:D009765 Obesity pirinixic acid 1.7320558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.1516049721 12819281
MESH:D009845 Oligospermia 2-ethoxyethanol 10.2920172899
MESH:D009845 Oligospermia methyl cellosolve 10.293987992
MESH:D010024 Osteoporosis icariin 4.4118236786 19747809
MESH:D012516 Osteosarcoma Doxorubicin 3.8615930896
MESH:D010051 Ovarian Neoplasms sodium arsenite 4.5217306315 15276417
MESH:D010051 Ovarian Neoplasms Tretinoin 4.5216936753
MESH:D010146 Pain Acetaminophen 5.7316870215
MESH:D010146 Pain Tretinoin 5.7316870215
MESH:D010190 Pancreatic Neoplasms Ethanol 8.0512384795
MESH:D010190 Pancreatic Neoplasms Tetradecanoylphorbol Acetate 8.0515976015
MESH:D010190 Pancreatic Neoplasms Tretinoin 8.0515976015
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.3911578682
MESH:D010212 Papilloma Tetradecanoylphorbol Acetate 3.9818404319 12065085 18922899 8330346
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 3.9212520081
MESH:D003557 Phyllodes Tumor Doxorubicin 4.8317983394
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 4.5710923243
MESH:D010997 Pleural Neoplasms Doxorubicin 4.8317638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.2518163543
MESH:D011225 Pre-Eclampsia Zinc 3.9317114810
MESH:D011297 Prenatal Exposure Delayed Effects 2-ethoxyethanol 14.662884743 7198755 6499817
MESH:D011297 Prenatal Exposure Delayed Effects methyl cellosolve 14.667974496 6499817 12530607
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 14.6611399792 11118676 11222880 11896295
MESH:D011471 Prostatic Neoplasms Azacitidine 1.9218324645
MESH:D011471 Prostatic Neoplasms Doxorubicin 1.9216729912 16888761 18437689 16868541 15749863 15897917
MESH:D011471 Prostatic Neoplasms sodium arsenite 1.9216039940
MESH:D011471 Prostatic Neoplasms Vitamin E 1.9215084515
MESH:D011471 Prostatic Neoplasms Zinc 1.9216517595 12429649 16700911 16606632
MESH:D011507 Proteinuria Tretinoin 3.3116636307
MESH:D011537 Pruritus Ethinyl Estradiol 2.9915861022 16919318
MESH:D011625 Pterygium Tretinoin 4.4716723453
MESH:D011654 Pulmonary Edema Isoproterenol 4.9210903255
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 2.9017365031 17975199 17322281 15814490
MESH:D051437 Renal Insufficiency Doxorubicin 3.9017922066
MESH:D015427 Reperfusion Injury pirinixic acid 2.2319058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.5318990726
MESH:D012162 Retinal Degeneration Zinc 3.8916584753
MESH:D012208 Rhabdomyosarcoma Tretinoin 3.8016116481 16283617
MESH:D012509 Sarcoma Doxorubicin 3.7115675481 17203757 18313854 17710206 15625365 16767912
MESH:D012512 Sarcoma, Ewing's Doxorubicin 3.9316326096 14601052
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.4617846226
MESH:D012640 Seizures 2,4-dinitrotoluene 5.3718551238
MESH:D012640 Seizures Ethanol 5.379754883
MESH:D012852 Sinusitis Phenylephrine 4.387327846
MESH:D012871 Skin Diseases Vitamin E 2.3618709164
MESH:D012878 Skin Neoplasms Doxorubicin 16.2715692506
MESH:D012878 Skin Neoplasms sodium arsenite 16.2719524636 18572023
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 16.2716192470
MESH:D012878 Skin Neoplasms Tetradecanoylphorbol Acetate 16.2712065085 8985016 11807781 18404319 8330346
MESH:D012878 Skin Neoplasms Tretinoin 16.2716467112
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.2516767912 15625365 17203757
MESH:D013088 Spermatocele Ethinyl Estradiol 3.6116709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.5512854658
MESH:D013274 Stomach Neoplasms Ethanol 2.5318456281
MESH:D013274 Stomach Neoplasms Tretinoin 2.5317261132
MESH:D013276 Stomach Ulcer 2-ethoxyethanol 6.936499799
MESH:D013276 Stomach Ulcer Ethanol 6.9311906479 17189318 17918041 16755016 9562338 9211565
MESH:D020521 Stroke Vitamin E 3.2716517955
MESH:D013375 Substance Withdrawal Syndrome Ethanol 3.979754883
MESH:D013733 Testicular Diseases 2-ethoxyethanol 9.9810514026 6499806 10048760
MESH:D013733 Testicular Diseases methyl cellosolve 9.986499806
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.3211994571
MESH:D013927 Thrombosis Ethinyl Estradiol 2.8815669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.5712697716
MESH:D013964 Thyroid Neoplasms Doxorubicin 6.5017909728 16010429
MESH:D013964 Thyroid Neoplasms Tretinoin 6.5017045167 16026305
MESH:D014062 Tongue Neoplasms Tretinoin 9.0416051514
MESH:D014062 Tongue Neoplasms Zinc 9.0416543248
MESH:D014376 Tuberculosis Tretinoin 3.0316040207
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 7.6016049721
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 7.6017653716
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 7.6017306315 11723127 16712894 16452187
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 3.9910091137
MESH:D014581 Urticaria Acetaminophen 2.6810982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 8.4811813266
MESH:D002583 Uterine Cervical Neoplasms Tretinoin 8.4816129372
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 2.9914692618
MESH:D014604 Uveal Neoplasms Tretinoin 4.2816752155
MESH:D014652 Vascular Diseases sodium arsenite 4.1017056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.2612125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.2515869587 14671159
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 9.5817334414 17638931 17678736 16364871
MESH:D018487 Ventricular Dysfunction, Left Isoproterenol 9.5818097624
MESH:D020257 Ventricular Remodeling Isoproterenol 5.3618097624
MESH:D014820 Vitiligo Tretinoin 3.7516761959
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 3.9215886252
MESH:D009396 Wilms Tumor Tretinoin 3.6916287080
Pathway ID Pathway Name
REACT:604 Hemostasis
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28587
  • Releated gene ID Related gene Name
    PA124CYP2C19
    PA126CYP2C9
    Releated disease ID Related disease Name
    PA152241952Congenital diaphragmatic hernia
    PA444929Mental Retardation
    PA444367Heart Defects, Congenital
    Releated drug ID Related drug Name
    PA449167cyclosporine
    PA451578tacrolimus
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018