Gene Symbol:	FGF20 ( FGF-20 )
Gene Full Name:	fibroblast growth factor 20
Band:	8p22
Quick Links	Entrez ID:26281; OMIM: 605558; Uniprot ID:FGF20_HUMAN; ENSEMBL ID: ENSG00000078579; HGNC ID: 3677
Relate to Another Database:	SFARIGene; denovo-db

Pathway ID	Pathway Name
hsa04010	MAPK signaling pathway
hsa04810	Regulation of actin cytoskeleton
hsa05218	Melanoma
hsa05200	Pathways in cancer

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D000643	Ammonium Chloride	Ammonium Chloride affects the expression of FGF20 mRNA	affects expression	16483693
D004390	Chlorpyrifos	Chlorpyrifos results in decreased expression of FGF20 mRNA	decreases expression	18502319 17589599
D003976	Diazinon	Diazinon results in decreased expression of FGF20 mRNA	decreases expression	17589599
C093973	PD 98059	PD 98059 inhibits the reaction [FGF20 protein results in increased phosphorylation of MAPK1 protein]	decreases reaction\|increases phosphorylation	12704805
C093973	PD 98059	PD 98059 inhibits the reaction [FGF20 protein results in increased phosphorylation of MAPK3 protein]	decreases reaction\|increases phosphorylation	12704805
C093973	PD 98059	PD 98059 results in decreased activity of FGF20 protein	decreases activity	12704805
D015232	Dinoprostone	FGF20 protein results in increased abundance of Dinoprostone	increases abundance	12360478
C105686	SU 5402	SU 5402 results in decreased activity of FGF20 protein	decreases activity	12704805

Disease ID	Disease Name	Direct Evidence	Inference Chemical Name	Inference Score	Publication
MESH:D000138	Acidosis		Ammonium Chloride	4.02	18287403
MESH:D011125	Adenomatous Polyposis Coli		Dinoprostone	5.33	17942926
MESH:D000382	Agricultural Workers' Diseases		Chlorpyrifos	10.76	17119214 16611668 11874814
MESH:D000382	Agricultural Workers' Diseases		Diazinon	10.76	16487989
MESH:D001014	Aortic Aneurysm		Dinoprostone	5.99	10231640
MESH:D017544	Aortic Aneurysm, Abdominal		Dinoprostone	6.05	10388637
MESH:D001477	Bartter Syndrome		Dinoprostone	6.16	15976003
MESH:D002471	Cell Transformation, Neoplastic		Dinoprostone	4.42	16192471
MESH:D003967	Diarrhea		Dinoprostone	4.93	11488427 10446763 7237001
MESH:D004417	Dyspnea		Diazinon	5.32	16487989
MESH:D005334	Fever		Dinoprostone	5.18	11852909 16997862
MESH:D006505	Hepatitis		Diazinon	4.95	16487989
MESH:D006930	Hyperalgesia		Dinoprostone	4.78	16793879
MESH:D007248	Infertility, Male		Diazinon	4.02	12948887 16466525
MESH:D007948	Leukemia, Monocytic, Acute		PD 98059	5.69	16972261
MESH:D008106	Liver Cirrhosis, Experimental		Dinoprostone	3.13	15816358
MESH:D008107	Liver Diseases		Chlorpyrifos	5.15	15991261
MESH:D008107	Liver Diseases		Dinoprostone	5.15	15816358
MESH:D020326	Migraine without Aura		Dinoprostone	5.64	11304026
MESH:D020258	Neurotoxicity Syndromes		Chlorpyrifos	4.37	15081274
MESH:D010005	Osteoarthropathy, Secondary Hypertrophic		Dinoprostone	7.00	18500342
MESH:D010300	Parkinson Disease	marker/mechanism
MESH:D011041	Poisoning		Diazinon	4.70	17603234
MESH:D012135	Respiratory Sounds		Chlorpyrifos	5.05	17119214 16611668 11874814
MESH:D012140	Respiratory Tract Diseases		Chlorpyrifos	5.41	17119214 16611668
MESH:D012729	Sex Chromosome Aberrations		Chlorpyrifos	6.61	6418539
MESH:D014570	Urologic Diseases		Diazinon	5.80	16487989

Pathway ID	Pathway Name
KEGG:04010	MAPK signaling pathway
KEGG:05218	Melanoma
KEGG:05200	Pathways in cancer
KEGG:04810	Regulation of actin cytoskeleton
REACT:9470	Signaling by FGFR
REACT:498	Signaling by Insulin receptor

Desease ID	Desease Name
1709	Parkinson disease
2053	Colon cancer

Desease Name
Parkinson's disease
NEUROLOGICAL

AutismKB 2.0

Annotation Detail for FGF20

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Syndromic Genes

Non-syndromic Genes

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