Annotation Detail for AK5
Basic Information Top
| Gene Symbol: | AK5 ( AK6,MGC33326 ) |
|---|---|
| Gene Full Name: | adenylate kinase 5 |
| Band: | 1p31.1 |
| Quick Links | Entrez ID:26289; OMIM: 608009; Uniprot ID:KAD5_HUMAN; ENSEMBL ID: ENSG00000154027; HGNC ID: 365 |
| Relate to Another Database: | SFARIGene; denovo-db |
Related Diseases/Disorders| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| D000082 | Acetaminophen | MAP3K5 protein affects the reaction [Acetaminophen results in increased expression of AK5 mRNA] | affects reaction|increases expression | 18700144 |
| D001564 | Benzo(a)pyrene | Benzo(a)pyrene results in decreased expression of AK5 mRNA | decreases expression | 20064835 |
| D014415 | Tunicamycin | Tunicamycin results in increased expression of AK5 mRNA | increases expression | 17127020 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000230 | Adenocarcinoma | Benzo(a)pyrene | 2.06 | 20464547 20127859 | |
| MESH:D000236 | Adenoma | Benzo(a)pyrene | 2.88 | 6695378 | |
| MESH:D000799 | Angioedema | Acetaminophen | 4.71 | 10982225 | |
| MESH:D017544 | Aortic Aneurysm, Abdominal | Benzo(a)pyrene | 4.73 | 19183758 | |
| MESH:D001321 | Autistic Disorder | Acetaminophen | 1.39 | 18445737 | |
| MESH:D001943 | Breast Neoplasms | Benzo(a)pyrene | 1.99 | 17474063 20146248 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Acetaminophen | 1.41 | 3084413 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Benzo(a)pyrene | 2.14 | 20419170 | |
| MESH:D002386 | Cataract | Acetaminophen | 2.81 | 10977129 | |
| MESH:D056486 | Drug-Induced Liver Injury | Acetaminophen | 1.68 | 16781746 14550746 11834606 2444490 16081117 19923254 16227642 11529661 11421492 15619225 17562736 12594235 14725611 12540782 14986274 19164858 10774834 11743745 17522070 11739529 12705907 19420014 19370779 18071297 12392966 11461765 16177239 17906064 12958197 10915739 16485898 19739265 16109766 12153990 19085960 19416960 16393943 10663392 15968718 11287661 18713872 | |
| MESH:D056487 | Drug-Induced Liver Injury, Chronic | Acetaminophen | 4.96 | 19426721 | |
| MESH:D004938 | Esophageal Neoplasms | Benzo(a)pyrene | 2.09 | 16530937 | |
| MESH:D005756 | Gastritis | Acetaminophen | 4.54 | 16983495 | |
| MESH:D006330 | Heart Defects, Congenital | Benzo(a)pyrene | 2.85 | 20471113 | |
| MESH:D006930 | Hyperalgesia | Acetaminophen | 3.06 | 16870215 | |
| MESH:D007674 | Kidney Diseases | Acetaminophen | 2.42 | 15629191 12587719 | |
| MESH:D008107 | Liver Diseases | Acetaminophen | 1.71 | 12969438 12587719 19460945 16611625 16610002 11587558 19784758 19014921 | |
| MESH:D017114 | Liver Failure, Acute | Acetaminophen | 3.68 | 16871587 17185352 | |
| MESH:D008113 | Liver Neoplasms | Benzo(a)pyrene | 2.17 | 21137059 20195826 | |
| MESH:D008175 | Lung Neoplasms | Benzo(a)pyrene | 1.57 | 20464547 20135361 17053015 6695378 18520028 18569708 20869020 20064080 18816296 | |
| MESH:D008546 | Melanoma, Experimental | Acetaminophen | 4.22 | 19513568 | |
| MESH:D009062 | Mouth Neoplasms | Benzo(a)pyrene | 3.53 | 16381670 | |
| MESH:D009369 | Neoplasms | Benzo(a)pyrene | 2.35 | 11141357 | |
| MESH:D019636 | Neurodegenerative Diseases | Acetaminophen | 3.26 | 18514411 | |
| MESH:D010146 | Pain | Acetaminophen | 2.77 | 16870215 | |
| MESH:D011471 | Prostatic Neoplasms | Benzo(a)pyrene | 2.90 | 17292933 | |
| MESH:D012878 | Skin Neoplasms | Benzo(a)pyrene | 2.54 | 19755658 10029692 | |
| MESH:D013274 | Stomach Neoplasms | Benzo(a)pyrene | 1.56 | 20155912 2093021 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Benzo(a)pyrene | 2.31 | 17053015 | |
| MESH:D014581 | Urticaria | Acetaminophen | 3.50 | 10982225 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:01100 | Metabolic pathways |
| REACT:1698 | Metabolism of nucleotides |
| KEGG:00230 | Purine metabolism |