AutismKB 2.0

Annotation Detail for GC


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Basic Information Top
Gene Symbol:GC ( DBP,DBP/GC,GRD3,VDBG,VDBP )
Gene Full Name: group-specific component (vitamin D binding protein)
Band: 4q13.3
Quick LinksEntrez ID:2638; OMIM: 139200; Uniprot ID:VTDB_HUMAN; ENSEMBL ID: ENSG00000145321; HGNC ID: 4187
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
No data
No data
Pathway IDPathway Name
Hormone biosynthesis
Metabolism of vitamins and cofactors
Metabolism of lipids and lipoproteins
No data
Pathway IDPathway Name
P04396Vitamin D metabolism and pathway
Pathway IDPathway Name
500600Vitamin D (calciferol) metabolism
Related Diseases/Disorders Top
No data
Desease IDDesease Name
1804Chronic obstructive airway disease
1826Cystic fibrosis
1831Prostate cancer
1856Obesity
1867Liver failure
1901Endometriosis
1904Diabetes mellitus
1930Graves' disease
2029Tuberculosis
2138Osteoporosis
Desease Name
fasting plasma insulin levels
Bone Mineral Density
IMMUNE
METABOLIC
Graves disease
chronic obstructive pulmonary disease/COPD
Desease Name
Vitamin D insufficiency
Vitamin D levels
Desease Name
Graves disease, susceptibility to, 3
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of GC mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of GC mRNAaffects expression 17562736
D000082 Acetaminophen Acetaminophen affects the expression of GC proteinaffects expression 16099942
D000082 Acetaminophen Acetaminophen results in increased expression of GC proteinincreases expression 16687475
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GC proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of GC mRNAaffects expression 16483693
C015001 arsenite arsenite results in increased expression of GC mRNAincreases expression 18929588
C015001 arsenite TRP53 protein affects the reaction [arsenite results in increased expression of GC mRNA]affects reaction|increases expression 18929588
C095105 bexarotene bexarotene results in decreased expression of GC mRNAdecreases expression 16648578
C032036 bromobenzene bromobenzene results in increased expression of GC mRNAincreases expression 15056800
C055494 caffeic acid phenethyl ester [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNAaffects cotreatment|decreases expression 20360939
D002118 Calcium Calcium affects the expression of GC mRNAaffects expression 15913539
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GC mRNAaffects expression 17484886
D002995 Clofibric Acid [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GC mRNAaffects cotreatment|affects expression 17602206
D016572 Cyclosporine Cyclosporine results in decreased expression of GC mRNAdecreases expression 20106945
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with caffeic acid phenethyl ester] results in decreased expression of GC mRNAaffects cotreatment|decreases expression 20360939
D004052 Diethylnitrosamine [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of GC mRNAaffects cotreatment|affects expression 17602206
D002117 Calcitriol GC protein affects the transport of Calcitriolaffects transport 15820770
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of GC mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in increased expression of GC mRNAincreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GC mRNAaffects cotreatment|increases expression 17942748
C030957 methylmercury II methylmercury II results in decreased expression of GC mRNAdecreases expression 17905399
C017947 sodium arsenite sodium arsenite affects the expression of GC mRNAaffects expression 17450228
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of GC mRNAaffects cotreatment|increases expression 17942748
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.8111752688 14514962 15322242
MESH:D000138 Acidosis Ammonium Chloride 3.5218287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 3.9117505938
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 1.8014692618
MESH:D000236 Adenoma Diethylnitrosamine 2.826695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 9.9419052882 19061943 17620307 16434500 18056438 17162532
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 9.9416835633
MESH:D000310 Adrenal Gland Neoplasms sodium arsenite 4.6715276417
MESH:D018246 Adrenocortical Adenoma sodium arsenite 4.8717306315 16712894
MESH:D000740 Anemia Tetrachlorodibenzodioxin 2.9111748828
MESH:D000799 Angioedema Acetaminophen 3.8110982225
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.4211256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6415885639
MESH:D001321 Autistic Disorder Acetaminophen 1.4218445737
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 3.0012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.7615340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.7315746008
MESH:D001943 Breast Neoplasms bexarotene 1.9816818667 16344269
MESH:D001943 Breast Neoplasms Calcitriol 1.9811237771
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9817474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9820435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.7416227642 16050911 15721981 16192424 15700767 16097048 15673190 16124888 3786805 10355542 18705752 16011737
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.7616835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.3116705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 11.313084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.3121507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.3118788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 11.3118691550 18788625 19701751 19539802 19519916 16878318 11831363 17761372 16807293 18393292 20007298 17978847 19335982 16502159 21159647 17138121 19383236 17173139 20432363 20727157 16698587 19171122 19107877 16328049 16681979 18210153 16540662 16288022 16779866 19052882 20935162 20514400 19822196 3084413 18056438 19208518 20084675 20214788 18506893 16569478 20524982 19418558 18785209 16935385 18494052 18665156 3581430 10737359 18978308 17055752 19394651 19919837 16830150 20512989 17428255 10672840 20101231 18971187 17162532
MESH:D006528 Carcinoma, Hepatocellular sodium arsenite 11.3116507464 17306315 15276417
MESH:D002289 Carcinoma, Non-Small-Cell Lung bexarotene 3.2116247446
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 4.7711237771
MESH:D002294 Carcinoma, Squamous Cell sodium arsenite 4.7718572023
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3418670907 16120746 18850075
MESH:D002386 Cataract Acetaminophen 2.5510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 15.776135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 15.7712371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 15.7717174075 2727394 21159647 7505956
MESH:D002471 Cell Transformation, Neoplastic sodium arsenite 15.7719524636 20056578
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.2019052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.2016835633
MESH:D002779 Cholestasis Cyclosporine 7.6619486331
MESH:D002779 Cholestasis Ethinyl Estradiol 7.6616105132 17333356 16919318 15861022 17681005 11677210 17110522
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.0816354765 15668235 8697196 12621046 15340226
MESH:D003110 Colonic Neoplasms arsenite 2.5815037631
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.0214669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2510048152 20055451 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 3.9818551238
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.1820387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.1817107852
MESH:D056486 Drug-Induced Liver Injury marker/mechanism 16099942
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 15.1118551238 21346803
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 15.1116393943 16081117 11739529 10915739 11529661 19739265 12392966 16109766 12594235 12705907 16485898 11834606 19164858 19923254 19370779 17522070 17562736 17906064 19420014 16227642 14550746 11421492 10663392 19085960 12540782 16177239 10774834 14725611 15619225 12958197 11743745 15968718 12153990 16781746 11461765 11287661 18071297 14986274 18713872 2444490 19416960
MESH:D056486 Drug-Induced Liver Injury bromobenzene 15.1112628495 10092053
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 15.1116227642 19336974 10915739 15027814 19085960 3732212 4309450 7120509 9327722 3786805 2869522 7179309 10092053 11566570 17522070 6623471 15968718 15998439 21278145 7440962 6884620 16177239
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 15.1119107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 15.1120420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.0719426721
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.7311462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.3411000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.8718230668 15322242 16714409
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 8.9615138306
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 8.9612538720
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.9810568697 9294722
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.0916302075
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9811564622
MESH:D005234 Fatty Liver arsenite 24.2318296743
MESH:D005234 Fatty Liver Carbon Tetrachloride 24.2361145 16239168 12795759 16045604 15959796 17595544 12631006 19224547
MESH:D005234 Fatty Liver Cyclosporine 24.2319224547
MESH:D005234 Fatty Liver Diethylnitrosamine 24.2320387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 24.2315345470
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.4211858732
MESH:D005355 Fibrosis arsenite 20.8518296743
MESH:D005355 Fibrosis Carbon Tetrachloride 20.8518705752
MESH:D005355 Fibrosis Cyclosporine 20.8512639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 20.8520067830
MESH:D005756 Gastritis Acetaminophen 3.6516983495
MESH:D005833 Genital Neoplasms, Female sodium arsenite 4.6416452187
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.188708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.5710696789
MESH:D006111 Graves Disease marker/mechanism
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.3110048152 11294989
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.3915720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.5519110552 19900420
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.8516120746 15340226 12621046
MESH:D006689 Hodgkin Disease sodium arsenite 3.1112676792
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.0218606429 15340226 16354765 8697196 16959395
MESH:D006930 Hyperalgesia Acetaminophen 2.6616870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.5016899240
MESH:D006973 Hypertension Cyclosporine 4.8910903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 4.8918670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.0515338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.7716569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.4212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 6.5417937319
MESH:D007248 Infertility, Male sodium arsenite 6.5412646999 15346721
MESH:D007249 Inflammation Diethylnitrosamine 4.8218785209
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 4.8212200463 12878042
MESH:D007414 Intestinal Neoplasms caffeic acid phenethyl ester 4.5510783313
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.4115604871
MESH:D007674 Kidney Diseases Acetaminophen 14.2515629191 12587719
MESH:D007674 Kidney Diseases caffeic acid phenethyl ester 14.2515369732
MESH:D007674 Kidney Diseases Cyclosporine 14.258314463 10903974 18776723
MESH:D007674 Kidney Diseases sodium arsenite 14.2520008137
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.1516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 7.1512371664
MESH:D007683 Kidney Tubular Necrosis, Acute Calcium 5.0216316344
MESH:D015473 Leukemia, Promyelocytic, Acute caffeic acid phenethyl ester 3.9616766008
MESH:D008103 Liver Cirrhosis arsenite 10.9518296743
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 10.9517174718 16943688 16239168 11408273 11903743 21278145 17157831 17334410 16221502
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 10.9520032147 19638242 18522880 18665156 18407596
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 2.2714716496 15893842 12898905 17900296 18277467 18166357 17869086 17976157 18395914 16097048 18472332 17944888 17708605 16192424 15370692 10355542 14512876 12609069 17823541 12958196 12666154 16011737 12389079 15650968 12649538 13678700 17698563 18395095 15818738 18279442 15925388 15057751 14620537 17766677 18006644 18187930 18472094 14716833 14748882 14724832 18412020 15052691 16638106 20821823 12546737 12632512 18251166 18420326 18376398 17721639 17714472 12586293 18054572 11481614 16015684 16033810 17761835 18205269 17557913 17631135 16136751 15959796 12445418 15996030 17481882 18481824 16248980 18317297 15338365 18339082 18156304 18263696 12445421 15123356 17640975 15362042 18210741 18705752 18429990 12741479 17525996 16116963 15730626 17922224 17805973 15931870 18418968 16027843 15876570 17565644 12632514 12667390 15673190
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.2712878042
MESH:D008107 Liver Diseases Acetaminophen 6.4119014921 19460945 11587558 12969438 16610002 19784758 12587719 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.4116964402 17285989 16246199 15830285 15720792
MESH:D008107 Liver Diseases Diethylnitrosamine 6.4117034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.1215123358
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2816871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 9.2814706259 16899240
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 21.677678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 21.6718177683 15890375 9163691 2125692
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 21.6719294768
MESH:D008113 Liver Neoplasms Clofibric Acid 21.6717602206
MESH:D008113 Liver Neoplasms Diethylnitrosamine 21.6718644402 19833225 19254457 20492335 15175105 19255062 19812893 15885732 19690152 20583210 12112319 19642983 18648771 19996281 20452335 19073162 21278145 2422723 19426721 16942905 20101389 19256749 18754104 20501860 12771043 19427195 20137499 2862719 19294768 21047994 18977376 10737359 19551842 21071580 19090486 19499222 20434301 18978307 19850985 21167192 20118626 9163691 19638242 20405173
MESH:D008113 Liver Neoplasms sodium arsenite 21.6716712894 15276417
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 21.6716984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 18.352876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 18.358603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 18.3515583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 18.3518775883 19126423 16267830 9362446 18544905 18308698 19539802 17942915 18079962 21159647 19009564 18253720 17854601 16842330 2563599 3124819 19004024 17174075 18282651 19519916 18164116 18093689
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 18.3512151625
MESH:D008171 Lung Diseases sodium arsenite 3.1419095001
MESH:D008175 Lung Neoplasms marker/mechanism 17902193
MESH:D008175 Lung Neoplasms Aflatoxin B1 8.5014755239
MESH:D008175 Lung Neoplasms arsenite 8.5016809336
MESH:D008175 Lung Neoplasms bexarotene 8.5017849452
MESH:D008175 Lung Neoplasms Diethylnitrosamine 8.5020970405 6695378 21163286 20512841
MESH:D008175 Lung Neoplasms sodium arsenite 8.5016712894 19931552 17306315 15276417 17077188
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 8.5011884234 19555203
MESH:D016410 Lymphoma, T-Cell, Cutaneous bexarotene 5.1111161223
MESH:D008325 Mammary Neoplasms, Experimental bexarotene 3.3815591091 19196722 19196723
MESH:D008545 Melanoma sodium arsenite 2.0316487513 19082730
MESH:D008546 Melanoma, Experimental Acetaminophen 3.5319513568
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.7616801185
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 2.9812213967
MESH:D009336 Necrosis 2,6-dinitrotoluene 3.837678174 18551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 2.559029167 3581430
MESH:D009369 Neoplasms sodium arsenite 2.4811559025
MESH:D009374 Neoplasms, Experimental sodium arsenite 3.6320056578
MESH:D009376 Neoplasms, Hormone-Dependent bexarotene 4.7519196722
MESH:D009389 Neovascularization, Pathologic arsenite 4.3815738583
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.4117954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.2419348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.1714600291
MESH:D009436 Neural Tube Defects sodium arsenite 3.1112854658
MESH:D019636 Neurodegenerative Diseases Acetaminophen 8.0618514411
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 8.0620387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.0920387270
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.3916049721
MESH:D010024 Osteoporosis Calcium 3.7517882678
MESH:D010051 Ovarian Neoplasms sodium arsenite 2.4217306315 15276417
MESH:D010146 Pain Acetaminophen 2.3516870215
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4116540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.6511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.2212520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.5218163543
MESH:D011230 Precancerous Conditions Cyclosporine 8.8212371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 8.822563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.1611222880 11399792 11896295 11118676
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.7415572423
MESH:D011471 Prostatic Neoplasms Calcitriol 3.4115754350 16289102 16644109 12479363 18247401
MESH:D011471 Prostatic Neoplasms sodium arsenite 3.4116039940
MESH:D011537 Pruritus Ethinyl Estradiol 3.2816919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2116882103
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.8018990726
MESH:D012640 Seizures 2,6-dinitrotoluene 2.5018551238
MESH:D012878 Skin Neoplasms sodium arsenite 5.5218572023 19524636
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5216192470
MESH:D013088 Spermatocele Ethinyl Estradiol 3.9116709447
MESH:D016135 Spinal Dysraphism sodium arsenite 3.7612854658
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 1.7518456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.5811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.1115669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.8712697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 2.957505956
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.0416049721
MESH:D001749 Urinary Bladder Neoplasms sodium arsenite 5.0411723127 16712894 16452187 17306315
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.2810091137
MESH:D014581 Urticaria Acetaminophen 2.9410982225
MESH:D002583 Uterine Cervical Neoplasms sodium arsenite 3.7311813266
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.2614692618
MESH:D014605 Uveitis Cyclosporine 3.961336536
MESH:D014652 Vascular Diseases sodium arsenite 4.3917056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.5712125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5014671159 15869587
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.2215886252
MESH:D014985 Xerophthalmia Cyclosporine 4.4117120751
Pathway ID Pathway Name
REACT:15314 Hormone biosynthesis
REACT:22258 Metabolism of lipids and lipoproteins
REACT:11193 Metabolism of vitamins and cofactors
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28601
    • No data
    Releated disease ID Related disease Name
    PA443450Asthma
    PA443879Dermatitis, Atopic
    Releated drug ID Related drug Name
    PA448717calcitriol
    Drug Bank Top
    No data
    No data
    No data
    Drugbank ID Action Drug Name Description
    DB00169 - Women's Timed Release Ultra Mega Without Iron Essential Vitamin;Antihypocalcemic Agents;Antihypoparathyroid Agents;Vitamins (Vitamin D);Bone Density Conservation Agents;Vitamins
    DB01436 substrate Alfacalcidol Bone Density Conservation Agents
    DB04224 - Oleic Acid

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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