Gene Symbol:	KAT2A ( GCN5,GCN5L2,MGC102791,PCAF-b,hGCN5 )
Gene Full Name:	K(lysine) acetyltransferase 2A
Band:	17q21.2
Quick Links	Entrez ID:2648; OMIM: 602301; Uniprot ID:KAT2A_HUMAN; ENSEMBL ID: ENSG00000108773; HGNC ID: 4201
Relate to Another Database:	SFARIGene; denovo-db

Pathway ID	Pathway Name
200002	Regulation of nuclear SMAD2/3 signaling
200093	C-MYC pathway
200045	Validated targets of C-MYC transcriptional activation

Chemical ID	Chemical Name	Interaction	Interaction Action	Publication
D003994	Bucladesine	Bucladesine inhibits the reaction [CTBP1 protein binds to KAT2A protein]	affects binding\|decreases reaction	18184656
C017947	sodium arsenite	sodium arsenite results in decreased expression of KAT2A mRNA	decreases expression	19822182

Disease ID	Disease Name	Inference Chemical Name	Inference Score	Publication
MESH:D000310	Adrenal Gland Neoplasms	sodium arsenite	5.77	15276417
MESH:D018246	Adrenocortical Adenoma	sodium arsenite	5.97	16712894 17306315
MESH:D006528	Carcinoma, Hepatocellular	sodium arsenite	2.01	15276417 17306315 16507464
MESH:D002294	Carcinoma, Squamous Cell	sodium arsenite	2.48	18572023
MESH:D002471	Cell Transformation, Neoplastic	sodium arsenite	3.31	19524636 20056578
MESH:D005833	Genital Neoplasms, Female	sodium arsenite	5.57	16452187
MESH:D006689	Hodgkin Disease	sodium arsenite	3.62	12676792
MESH:D007248	Infertility, Male	sodium arsenite	3.29	12646999 15346721
MESH:D007674	Kidney Diseases	sodium arsenite	3.04	20008137
MESH:D008113	Liver Neoplasms	sodium arsenite	2.51	16712894 15276417
MESH:D008171	Lung Diseases	sodium arsenite	3.48	19095001
MESH:D008175	Lung Neoplasms	sodium arsenite	1.90	17306315 19931552 16712894 15276417 17077188
MESH:D008545	Melanoma	sodium arsenite	2.08	19082730 16487513
MESH:D009369	Neoplasms	sodium arsenite	2.69	11559025
MESH:D009374	Neoplasms, Experimental	sodium arsenite	4.43	20056578
MESH:D009436	Neural Tube Defects	sodium arsenite	3.44	12854658
MESH:D010051	Ovarian Neoplasms	sodium arsenite	2.54	17306315 15276417
MESH:D011471	Prostatic Neoplasms	sodium arsenite	3.23	16039940
MESH:D012878	Skin Neoplasms	sodium arsenite	2.88	19524636 18572023
MESH:D016135	Spinal Dysraphism	sodium arsenite	4.18	12854658
MESH:D001749	Urinary Bladder Neoplasms	sodium arsenite	2.65	11723127 17306315 16452187 16712894
MESH:D002583	Uterine Cervical Neoplasms	sodium arsenite	4.27	11813266
MESH:D014652	Vascular Diseases	sodium arsenite	5.31	17056641

AutismKB 2.0

Annotation Detail for KAT2A

Simple Query:

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics