AutismKB 2.0

Annotation Detail for NARF


View Evidences View Variants View Annotations
Basic Information Top
Gene Symbol:NARF ( DKFZp434G0420,FLJ10067,IOP2 )
Gene Full Name: nuclear prelamin A recognition factor
Band: 17q25.3
Quick LinksEntrez ID:26502; OMIM: 605349; Uniprot ID:NARF_HUMAN; ENSEMBL ID: ENSG00000141562; HGNC ID: 29916
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of NARF mRNAaffects expression 21346803
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of NARF mRNAaffects expression 21346803
D000082 Acetaminophen Acetaminophen affects the expression of NARF mRNAaffects expression 17562736
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of NARF mRNAaffects expression 17484886
D010634 Phenobarbital Phenobarbital results in increased expression of NARF mRNAincreases expression 19270015
D012645 Selenomethionine Selenomethionine affects the expression of NARF mRNAaffects expression 17222674
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Phenobarbital 3.906195326
MESH:D018248 Adenoma, Liver Cell Phenobarbital 4.4317620307
MESH:D000799 Angioedema Acetaminophen 4.3610982225
MESH:D001321 Autistic Disorder Acetaminophen 1.4018445737
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 4.2016227642 10355542 18705752 16011737 15673190 16124888 15700767 16050911 15721981 16192424 16097048 3786805
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 9.3016705839
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 9.3016705839
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 9.303084413
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 9.3018788625
MESH:D006528 Carcinoma, Hepatocellular Phenobarbital 9.3020935162 1701930 6705139 17173139 20007298
MESH:D002386 Cataract Acetaminophen 2.7510977129
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 2.986135515
MESH:D002493 Central Nervous System Diseases Phenobarbital 4.674080065
MESH:D003490 Cyanosis 2,4-dinitrotoluene 12.3218551238
MESH:D003490 Cyanosis 2,6-dinitrotoluene 12.3218551238
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.6218551238 21346803
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 9.6221346803 18551238
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 9.6210663392 11287661 10774834 19085960 11743745 16177239 14550746 16227642 12540782 16081117 11461765 12958197 19416960 19739265 19420014 16109766 11739529 19164858 12392966 14725611 15619225 17522070 18713872 16781746 12153990 14986274 11529661 12594235 18071297 15968718 17562736 12705907 16485898 11421492 19370779 19923254 2444490 10915739 17906064 16393943 11834606
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.6210092053 6884620 6623471 9327722 11566570 16227642 7120509 10915739 7440962 21278145 15998439 4309450 15027814 17522070 3786805 15968718 19336974 2869522 3732212 19085960 7179309 16177239
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 4.6219426721
MESH:D004421 Dystonia Phenobarbital 4.361851702
MESH:D004831 Epilepsies, Myoclonic Phenobarbital 4.533659116
MESH:D004828 Epilepsies, Partial Phenobarbital 4.3911558140 3922381
MESH:D004827 Epilepsy Phenobarbital 3.0320417680
MESH:D004832 Epilepsy, Absence Phenobarbital 3.836401628
MESH:D017029 Epilepsy, Complex Partial Phenobarbital 4.677750514
MESH:D004830 Epilepsy, Tonic-Clonic Phenobarbital 4.483659116
MESH:D005234 Fatty Liver Carbon Tetrachloride 3.4915959796 17595544 16045604 61145 12631006 19224547 12795759 16239168
MESH:D005355 Fibrosis Carbon Tetrachloride 3.8718705752
MESH:D005756 Gastritis Acetaminophen 4.1916983495
MESH:D006505 Hepatitis Carbon Tetrachloride 3.9719900420 19110552
MESH:D006529 Hepatomegaly Phenobarbital 3.9016109766
MESH:D006930 Hyperalgesia Acetaminophen 2.9516870215
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.9916899240
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.5015338365
MESH:D007674 Kidney Diseases Acetaminophen 2.3612587719 15629191
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 8.2716705839
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 8.2716705839
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 7.1511903743 17334410 11408273 16221502 16943688 17174718 16239168 17157831 21278145
MESH:D008103 Liver Cirrhosis Phenobarbital 7.1521047994
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 1.7515673190 11481614 17869086 12586293 17525996 17766677 15876570 16011737 15931870 12632512 12898905 18395095 15338365 18279442 18412020 18166357 16136751 15959796 18054572 14724832 16248980 12609069 17922224 18420326 18251166 12741479 16027843 17631135 18376398 18472332 18156304 15123356 17714472 18205269 18472094 15057751 18395914 17976157 16015684 18263696 18429990 14748882 12667390 16097048 12632514 12445421 14512876 15052691 15370692 18481824 12389079 17900296 17698563 18339082 17805973 17823541 12445418 16192424 17708605 18187930 15925388 18705752 12649538 17640975 14620537 16116963 18210741 17944888 12546737 17565644 18006644 17721639 15730626 12666154 17557913 12958196 15818738 14716833 16638106 15362042 17761835 10355542 17481882 13678700 18418968 18277467 15893842 15650968 15996030 16033810 18317297 20821823 14716496
MESH:D008107 Liver Diseases Acetaminophen 6.8811587558 12969438 16610002 19784758 12587719 19460945 19014921 16611625
MESH:D008107 Liver Diseases Carbon Tetrachloride 6.8816964402 17285989 15720792 15830285 16246199
MESH:D008107 Liver Diseases Phenobarbital 6.8819363144
MESH:D017093 Liver Failure Carbon Tetrachloride 4.5815123358
MESH:D017114 Liver Failure, Acute Acetaminophen 10.4416871587 17185352
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 10.4416899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 8.057678174
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 8.0519294768
MESH:D008113 Liver Neoplasms Phenobarbital 8.0515975961 8742319 19482888 19812893 21047994 19073162
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.946135515 2876784 2876786
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 10.9412014681 15583823
MESH:D008114 Liver Neoplasms, Experimental Phenobarbital 10.9418308698 6150874 17172636 2563599 1399818
MESH:D008546 Melanoma, Experimental Acetaminophen 3.9819513568
MESH:D020191 Myoclonic Epilepsies, Progressive Phenobarbital 4.9417484760
MESH:D009336 Necrosis 2,4-dinitrotoluene 11.9418551238
MESH:D009336 Necrosis 2,6-dinitrotoluene 11.947678174 18551238
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.1418514411
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 9.9212819281 16049721
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 9.9216049721
MESH:D010018 Osteomalacia Phenobarbital 4.8317016548
MESH:D010146 Pain Acetaminophen 2.6516870215
MESH:D010190 Pancreatic Neoplasms Phenobarbital 2.5816965848
MESH:D011230 Precancerous Conditions Phenobarbital 3.912563599
MESH:D019310 Pseudolymphoma Phenobarbital 5.0212752131
MESH:D012640 Seizures 2,4-dinitrotoluene 11.0418551238
MESH:D012640 Seizures 2,6-dinitrotoluene 11.0418551238
MESH:D012640 Seizures Phenobarbital 11.043137016 11442880 16876388 4039156
MESH:D003294 Seizures, Febrile Phenobarbital 5.286407741
MESH:D013964 Thyroid Neoplasms Phenobarbital 3.291399818
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 5.3616049721
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3616049721
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 13.5810091137
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 13.5810091137
MESH:D014581 Urticaria Acetaminophen 3.3310982225
No data
Pharmacogenomics Knowledge Base Top
Drug Bank Top

Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


Copyright © 2017, Center for Bioinformatics , Peking University | All Rights Reserved