Annotation Detail for ELP4
Basic Information
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| Gene Symbol: | ELP4 ( C11orf19,FLJ20498,PAX6NEB,PAXNEB,dJ68P15A.1 ) |
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| Gene Full Name: | elongation protein 4 homolog (S. cerevisiae) |
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| Band: | 11p13 |
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| Quick Links | Entrez ID:26610; OMIM: 606985; Uniprot ID:ELP4_HUMAN; ENSEMBL ID: ENSG00000109911; HGNC ID: 1171 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of ELP4 mRNA | decreases expression | 20064835
20106945
|
| D002117 |
Calcitriol |
Calcitriol results in increased expression of ELP4 mRNA | increases expression | 16002434
|
| C006253 |
pirinixic acid |
pirinixic acid results in increased expression of ELP4 mRNA | increases expression | 18301758
|
| C010327 |
salinomycin |
salinomycin results in decreased expression of ELP4 mRNA | decreases expression | 19682730
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
3.58 | 18653653 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.06 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.86 | 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.11 | 16434500 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.64 | 19183758 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.57 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.07 | 20146248 17474063 |
| MESH:D001943 |
Breast Neoplasms |
|
Calcitriol |
2.07 | 11237771 |
| MESH:D001943 |
Breast Neoplasms |
|
salinomycin |
2.07 | 19682730 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
4.99 | 20419170 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Calcitriol |
4.99 | 11237771 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.12 | 19176532 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.57 | 18249437 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.90 | 12083418 |
| MESH:D004681 |
Encephalomyelitis, Autoimmune, Experimental |
|
Calcitriol |
4.44 | 15138306 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.08 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.19 | 20131406 19236843 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.83 | 20471113 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.76 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.55 | 19176532 18467677 19772884 16221962 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.58 | 20558911 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.87 | 16306350 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.77 | 21137059 20195826 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.77 | 15890375 16377806 20007298 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20464547 20064080 18569708 20135361 18816296 6695378 18520028 20869020 17053015 |
| MESH:D008325 |
Mammary Neoplasms, Experimental |
|
salinomycin |
4.00 | 19682730 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.50 | 16381670 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
4.07 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.27 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.25 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
5.39 | 11141357 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.39 | 17405874 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D011470 |
Prostatic Hyperplasia |
|
Calcitriol |
5.41 | 15572423 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
3.19 | 17292933 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Calcitriol |
3.19 | 18247401 16644109 16289102 12479363 15754350 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.55 | 19058328 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.52 | 10029692 19755658 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.30 | 17053015 |
Related Pathway Information