AutismKB 2.0

Annotation Detail for GEM


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Basic Information Top
Gene Symbol:GEM ( KIR,MGC26294 )
Gene Full Name: GTP binding protein overexpressed in skeletal muscle
Band: 8q22.1
Quick LinksEntrez ID:2669; OMIM: 600164; Uniprot ID:GEM_HUMAN; ENSEMBL ID: ENSG00000164949; HGNC ID: 4234
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene results in decreased expression of GEM mRNAdecreases expression 20406850
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of GEM proteinaffects expression 20106945
D000638 Amiodarone Amiodarone results in increased expression of GEM mRNAincreases expression 19774075
D017638 Asbestos, Crocidolite Asbestos, Crocidolite results in increased expression of GEM mRNAincreases expression 18687144
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of GEM mRNAaffects expression 17484886
D016572 Cyclosporine Cyclosporine results in increased expression of GEM mRNAincreases expression 20106945
D002117 Calcitriol Calcitriol results in increased expression of GEM mRNAincreases expression 14996990
16002434
D004317 Doxorubicin Doxorubicin affects the expression of GEM mRNAaffects expression 15205334
D004958 Estradiol [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of GEM mRNAaffects cotreatment|decreases expression 19619570
D004958 Estradiol Estradiol results in increased expression of GEM mRNAincreases expression 19619570
20106945
D004958 Estradiol Estradiol affects the expression of GEM mRNAaffects expression 15598610
D005472 Fluorouracil Fluorouracil affects the expression of GEM mRNAaffects expression 15205334
D013749 Tetrachlorodibenzodioxin [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of GEM mRNAaffects cotreatment|decreases expression 19619570
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of GEM mRNAdecreases expression 19619570
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.0415322242 14514962 11752688
MESH:D000230 Adenocarcinoma Doxorubicin 7.3517418594
MESH:D000230 Adenocarcinoma Estradiol 7.3511473722
MESH:D000230 Adenocarcinoma Fluorouracil 7.3517638652
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.5716835633
MESH:D000419 Albuminuria Doxorubicin 4.7021441931
MESH:D000740 Anemia Fluorouracil 9.1217963324 15504547 16511603
MESH:D000740 Anemia Tetrachlorodibenzodioxin 9.1211748828
MESH:D001145 Arrhythmias, Cardiac Amiodarone 3.9318218290 20041841 18057881
MESH:D001281 Atrial Fibrillation Amiodarone 4.0119698954 18651412
MESH:D001778 Blood Coagulation Disorders Amiodarone 9.5219483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.5212125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.0115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8515746008
MESH:D019046 Bone Marrow Neoplasms Doxorubicin 4.9214601052
MESH:D001932 Brain Neoplasms Doxorubicin 3.9417150277
MESH:D001943 Breast Neoplasms Calcitriol 2.3811237771
MESH:D001943 Breast Neoplasms Doxorubicin 2.3816322301 18695136 15668708 18382427 15993339 15939500 18234424 16935488 17983394 15567936 15634643 17426702 15994142 16115903 15692762 16264153 17369602 18628466 16826403 16096432 16595493 15136595 11325840 19526202
MESH:D001943 Breast Neoplasms Estradiol 2.3817261762 17289903 16675129 12948864 18497071 14630087 19861407 17018787
MESH:D001943 Breast Neoplasms Fluorouracil 2.3818608205 15136595 16595493 19217205 18357371 16557594 16110121
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.3820435547
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.6616111702
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.9515673190 16097048 16227642 3786805 15700767 18705752 15721981 16011737 16192424 16124888 16050911 10355542
MESH:D002276 Carcinoid Tumor Doxorubicin 13.0916051944
MESH:D002276 Carcinoid Tumor Fluorouracil 13.0916051944
MESH:D002277 Carcinoma Fluorouracil 8.5617121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.5616835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 11.6716705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 11.6712619106 21507988 12907637
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 11.6718788625
MESH:D006528 Carcinoma, Hepatocellular Doxorubicin 11.6716234567 18059187 17876044 16023760
MESH:D006528 Carcinoma, Hepatocellular Estradiol 11.6716924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 11.6717045692 17971768 16332177 17088986 16799960 18930000
MESH:D002292 Carcinoma, Renal Cell Doxorubicin 6.8716201981 1485588
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 6.8718695887
MESH:D002294 Carcinoma, Squamous Cell Calcitriol 7.8711237771
MESH:D002294 Carcinoma, Squamous Cell Doxorubicin 7.876189445
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 7.8716757204 16280240 18986760 17066447
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4416120746 18850075 18670907
MESH:D009202 Cardiomyopathies Doxorubicin 3.6217131338 17519947 16651473 16242529 17329180 17382496 16364871 17974986 15505089 17007740 15476868 17928571 17351982 16952015 16269455 16455267 16109756 17924179 17308081 15792986 18627295 15811867 16731534 16612575 16278810
MESH:D002311 Cardiomyopathy, Dilated Amiodarone 6.1219225199 15710769
MESH:D002311 Cardiomyopathy, Dilated Doxorubicin 6.1217334414 16243910
MESH:D002341 Carotid Artery Thrombosis Amiodarone 5.2818974383
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 11.706135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 11.7012371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 11.7018566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.2916835633
MESH:D002779 Cholestasis Cyclosporine 3.0219486331
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.158697196 16354765 15340226 15668235 12621046
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2516510598 16340194 15001691 17016597 18772588 17172411 17725105 17287894 17018589 17169374
MESH:D015179 Colorectal Neoplasms Doxorubicin 2.6818259882 18802399
MESH:D015179 Colorectal Neoplasms Fluorouracil 2.6816303861 16524972 17454858 18802399 18509181 15148649 15289873 20501625 17016601 16331619 18949393 18383874 16391804 17695437 14970324 17401013 17094418 16282729 17594712 17255274 18448328 18288408
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1817141729 14669216
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2620055451 10048152 15322242
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.1918551238
MESH:D007644 Darier Disease Fluorouracil 4.9916733453
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.6917107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.5419279558
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 12.4418551238 21346803
MESH:D056486 Drug-Induced Liver Injury Amiodarone 12.4418218290 15265979
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 12.4421278145 11566570 4309450 15027814 7440962 7120509 10915739 6884620 16177239 3732212 2869522 17522070 9327722 15998439 19085960 10092053 15968718 7179309 16227642 6623471 3786805 19336974
MESH:D056486 Drug-Induced Liver Injury Doxorubicin 12.4417416283
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 12.4420420201
MESH:D004362 Drug Toxicity Doxorubicin 8.4618602426
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 8.4611462148
MESH:D004487 Edema Tetrachlorodibenzodioxin 2.5111000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.1216714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Calcitriol 4.0915138306
MESH:D016889 Endometrial Neoplasms Doxorubicin 7.8317359293
MESH:D016889 Endometrial Neoplasms Estradiol 7.8319148513 11473722 18566989
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.1510568697 9294722
MESH:D004719 Endomyocardial Fibrosis Doxorubicin 5.3718037988
MESH:D004938 Esophageal Neoplasms Fluorouracil 2.4816337965 17638652 15173087 16481741 16785472
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1211564622
MESH:D005234 Fatty Liver Amiodarone 13.9814986274
MESH:D005234 Fatty Liver Carbon Tetrachloride 13.9812795759 17595544 15959796 61145 12631006 16239168 16045604 19224547
MESH:D005234 Fatty Liver Cyclosporine 13.9819224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.6311858732
MESH:D018222 Fibromatosis, Aggressive Doxorubicin 4.7819069698
MESH:D005355 Fibrosis Carbon Tetrachloride 15.7718705752
MESH:D005355 Fibrosis Cyclosporine 15.7712639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.7720067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.418708960
MESH:D005909 Glioblastoma Doxorubicin 3.4317150277
MESH:D005910 Glioma Fluorouracil 2.9216145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.8110696789
MESH:D006258 Head and Neck Neoplasms Doxorubicin 8.2315692506
MESH:D006258 Head and Neck Neoplasms Fluorouracil 8.2315162350 15102660 18337622
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 2.4011294989 10048152
MESH:D006331 Heart Diseases Doxorubicin 3.5816144979 16879835 16707910 17875725 16330681 18006777 18674790 16495754 12587719 14766674 16244372 16244371 17888722
MESH:D006333 Heart Failure Doxorubicin 3.4217481944
MESH:D006394 Hemangiosarcoma Doxorubicin 4.0415692506
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.6215720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.4811000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.7619110552 19900420
MESH:D006529 Hepatomegaly Amiodarone 9.1315265979
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.1312621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 5.2515709030
MESH:D006689 Hodgkin Disease Doxorubicin 3.5315147373 17606976 18501091
MESH:D019584 Hot Flashes Estradiol 3.9717088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.268697196 15340226 16959395 16354765 18606429
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.7316899240
MESH:D006937 Hypercholesterolemia Amiodarone 4.018137927 9751232
MESH:D006973 Hypertension Cyclosporine 5.1010903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1018670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.2615338365
MESH:D007037 Hypothyroidism Amiodarone 4.6917991464 18020914
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9212200463 12878042
MESH:D007333 Insulin Resistance Estradiol 3.0516393666 16627594
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.4816580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.6615604871
MESH:D007674 Kidney Diseases Cyclosporine 10.5418776723 10903974 8314463
MESH:D007674 Kidney Diseases Doxorubicin 10.5416775033 15369732 15699352
MESH:D007674 Kidney Diseases Estradiol 10.5415618244
MESH:D007676 Kidney Failure, Chronic Doxorubicin 4.2916707910
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 18.7616705839
MESH:D007680 Kidney Neoplasms Cyclosporine 18.7612371664
MESH:D007680 Kidney Neoplasms Estradiol 18.7615610895
MESH:D007680 Kidney Neoplasms Fluorouracil 18.7616985049
MESH:D004915 Leukemia, Erythroblastic, Acute Doxorubicin 5.3716085563
MESH:D008064 Lipidoses Amiodarone 3.6117567588 15342952
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 2.8816239168 11408273 17157831 16943688 16221502 21278145 11903743 17174718 17334410
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 5.0811481614 12649538 14724832 18395914 14620537 14748882 17900296 16136751 17944888 18277467 18481824 15931870 15925388 15673190 17823541 18412020 16097048 12958196 18705752 12632514 18006644 16638106 14512876 18376398 17698563 17761835 18166357 17708605 20821823 18472094 15057751 16015684 12389079 18472332 15370692 17557913 16033810 17869086 12666154 12741479 17721639 12898905 10355542 17805973 15893842 15996030 16192424 12546737 17976157 15730626 15650968 12445418 14716833 18210741 18263696 15818738 16027843 14716496 12632512 17922224 18339082 16248980 18156304 18054572 18429990 17714472 15959796 18251166 12667390 15338365 17525996 17481882 18418968 17565644 15876570 17766677 12445421 16011737 18420326 18395095 12609069 15362042 15052691 16116963 17631135 13678700 18205269 18317297 15123356 12586293 17640975 18187930 18279442
MESH:D008106 Liver Cirrhosis, Experimental Doxorubicin 5.0816439617 16595196
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 5.0814716833 14659978
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 5.0812878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 2.1115830285 17285989 16246199 16964402 15720792
MESH:D017093 Liver Failure Carbon Tetrachloride 4.3415123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.8216899240 14706259
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 14.777678174
MESH:D008113 Liver Neoplasms Aflatoxin B1 14.772125692 15890375 9163691 18177683
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 14.7719294768
MESH:D008113 Liver Neoplasms Fluorouracil 14.7716603448 17045692 18383874 15113037
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 14.7716984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 19.572876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 19.578603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 19.5715583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Doxorubicin 19.5716842330 17085340
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 19.5712151625
MESH:D008133 Long QT Syndrome Amiodarone 3.6917391786 15350150 11989578
MESH:D008171 Lung Diseases Amiodarone 3.4612587719
MESH:D017563 Lung Diseases, Interstitial Amiodarone 4.7018516814
MESH:D055370 Lung Injury Asbestos, Crocidolite 4.2017365036
MESH:D008175 Lung Neoplasms Aflatoxin B1 4.9814755239
MESH:D008175 Lung Neoplasms Doxorubicin 4.9817418594 6189445
MESH:D008175 Lung Neoplasms Fluorouracil 4.9815246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 4.9811884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.9915086387
MESH:D008223 Lymphoma Doxorubicin 3.5616098063
MESH:D008228 Lymphoma, Non-Hodgkin Doxorubicin 3.9117654614
MESH:D016399 Lymphoma, T-Cell Doxorubicin 4.7415621674
MESH:D008325 Mammary Neoplasms, Experimental Doxorubicin 6.4115458769
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 6.4111807958 16891317 11408345 17203775
MESH:D020149 Manganese Poisoning Estradiol 4.7019453300
MESH:D008545 Melanoma Doxorubicin 2.3016827129
MESH:D008654 Mesothelioma Asbestos, Crocidolite 6.6018303189 16966607 16166281
MESH:D008654 Mesothelioma Doxorubicin 6.6017638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.0116801185
MESH:D028361 Mitochondrial Diseases Doxorubicin 4.6415792986
MESH:D009062 Mouth Neoplasms Fluorouracil 3.7416757204 18986760
MESH:D052016 Mucositis Doxorubicin 4.9817415656
MESH:D009181 Mycoses Amiodarone 5.1212754197 17974566
MESH:D009203 Myocardial Infarction Doxorubicin 3.0015857846 19429709
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1312213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.3916810080
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.057678174 18551238
MESH:D009362 Neoplasm Metastasis Doxorubicin 3.0018259882
MESH:D009369 Neoplasms Fluorouracil 2.6718239605 18600527 16928823
MESH:D009389 Neovascularization, Pathologic Estradiol 3.9317289903
MESH:D009401 Nephrosis Doxorubicin 4.9416636307 16899518
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.6617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 9.7118481113 19348381
MESH:D009404 Nephrotic Syndrome Doxorubicin 9.7115640375 16889571
MESH:D009421 Nervous System Malformations Estradiol 10.0111399458 16427766
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 10.0114600291
MESH:D009447 Neuroblastoma Doxorubicin 3.3315555623
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.5316436463
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.5616049721
MESH:D012516 Osteosarcoma Doxorubicin 4.2315930896
MESH:D010051 Ovarian Neoplasms Estradiol 2.2519401270
MESH:D010190 Pancreatic Neoplasms Fluorouracil 2.7116929163 16500647 19003803 15113037
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.4712520081
MESH:D003557 Phyllodes Tumor Doxorubicin 5.3717983394
MESH:D010995 Pleural Diseases Asbestos, Crocidolite 5.0710923243
MESH:D010997 Pleural Neoplasms Doxorubicin 5.3717638057
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.7218163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.3512371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.3811222880 11118676 11399792 11896295
MESH:D011470 Prostatic Hyperplasia Calcitriol 4.9715572423
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 4.0220887781
MESH:D011471 Prostatic Neoplasms Calcitriol 2.0916289102 18247401 12479363 15754350 16644109
MESH:D011471 Prostatic Neoplasms Doxorubicin 2.0915749863 18437689 16868541 15897917 16888761 16729912
MESH:D011471 Prostatic Neoplasms Estradiol 2.0916740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 2.0919082440 18626508
MESH:D011565 Psoriasis Cyclosporine 2.2716882103
MESH:D011658 Pulmonary Fibrosis Amiodarone 6.0411597910 12490602 12832656
MESH:D011658 Pulmonary Fibrosis Asbestos, Crocidolite 6.0417975199 17365031 15814490 17322281
MESH:D012004 Rectal Neoplasms Fluorouracil 4.1418286688 18722050 16160472 15538739
MESH:D051437 Renal Insufficiency Doxorubicin 4.4017922066
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0018990726
MESH:D012509 Sarcoma Doxorubicin 4.1218313854 16767912 17203757 15625365 15675481 17710206
MESH:D012512 Sarcoma, Ewing's Doxorubicin 4.4014601052 16326096
MESH:D012514 Sarcoma, Kaposi Doxorubicin 4.9817846226
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6218551238
OMIM:609620 SHORT QT SYNDROME 1 Amiodarone 5.2818724381
MESH:D012878 Skin Neoplasms Doxorubicin 5.8915692506
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.8916192470
MESH:D012983 Soft Tissue Neoplasms Doxorubicin 4.7416767912 17203757 15625365
MESH:D013274 Stomach Neoplasms Fluorouracil 2.0017522103 16424979 19084572 18396642 19015929 16951190 17498489 15786421 18567086 17172411
MESH:D013276 Stomach Ulcer Amiodarone 3.4518087811
MESH:D013610 Tachycardia Amiodarone 4.4511238279
MESH:D017180 Tachycardia, Ventricular Amiodarone 4.3519225199
MESH:D013959 Thyroid Diseases Amiodarone 12.7919731979
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 12.7912697716
MESH:D013964 Thyroid Neoplasms Doxorubicin 3.4717909728 16010429
MESH:D013971 Thyrotoxicosis Amiodarone 5.0419584973 18020914
MESH:D013978 Tibial Fractures Estradiol 4.9019048282
MESH:D014062 Tongue Neoplasms Fluorouracil 4.1216280240
MESH:D016171 Torsades de Pointes Amiodarone 4.3811989578 17467628
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.3516049721
MESH:D001749 Urinary Bladder Neoplasms Doxorubicin 5.3517653716
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.5110091137
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 4.0116803524
MESH:D014605 Uveitis Cyclosporine 4.201336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.8112125929
MESH:D018487 Ventricular Dysfunction, Left Doxorubicin 4.4017334414 16364871 17678736 17638931
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.4715886252
MESH:D014985 Xerophthalmia Cyclosporine 4.6617120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA28645
    • No data
    Releated disease ID Related disease Name
    PA443560Breast Neoplasms
    Releated drug ID Related drug Name
    PA450196letrozole
    Drug Bank Top

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      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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