AutismKB 2.0

Annotation Detail for OPLAH


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Basic Information Top
Gene Symbol:OPLAH ( 5-Opase,DKFZp434H244,OPLA )
Gene Full Name: 5-oxoprolinase (ATP-hydrolysing)
Band: 8q24.3
Quick LinksEntrez ID:26873; OMIM: NA; Uniprot ID:OPLA_HUMAN; ENSEMBL ID: ENSG00000178814; HGNC ID: 8149
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Pathway IDPathway Name
PWY-4041gamma-glutamyl cycle
Pathway IDPathway Name
hsa00480Glutathione metabolism
No data
No data
No data
No data
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in increased expression of OPLAH mRNAincreases expression 19933214
C016403 2,4-dinitrotoluene 2,4-dinitrotoluene affects the expression of OPLAH mRNAaffects expression 21346803
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of OPLAH proteinaffects expression 20106945
D000643 Ammonium Chloride Ammonium Chloride affects the expression of OPLAH mRNAaffects expression 16483693
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of OPLAH mRNAdecreases expression 20106945
D002251 Carbon Tetrachloride Carbon Tetrachloride affects the expression of OPLAH mRNAaffects expression 17484886
D003345 Corticosterone Corticosterone results in increased expression of OPLAH mRNAincreases expression 15755911
D016572 Cyclosporine Cyclosporine results in decreased expression of OPLAH mRNAdecreases expression 20106945
D004052 Diethylnitrosamine Diethylnitrosamine results in decreased expression of OPLAH mRNAdecreases expression 19638242
D004997 Ethinyl Estradiol Ethinyl Estradiol affects the expression of OPLAH mRNAaffects expression 17555576
D004997 Ethinyl Estradiol Ethinyl Estradiol results in decreased expression of OPLAH mRNAdecreases expression 17942748
D004997 Ethinyl Estradiol [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of OPLAH mRNAaffects cotreatment|decreases expression 17942748
D008701 Methapyrilene Methapyrilene results in decreased expression of OPLAH mRNAdecreases expression 16393664
C006253 pirinixic acid [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of OPLAH mRNAaffects binding|increases activity|increases expression 19710929
C006253 pirinixic acid pirinixic acid results in increased expression of OPLAH mRNAincreases expression 17426115
18301758
D013629 Tamoxifen Tamoxifen affects the expression of OPLAH mRNAaffects expression 17555576
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of OPLAH mRNAaffects cotreatment|decreases expression 17942748
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of OPLAH mRNAincreases expression 19933214
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in decreased expression of OPLAH mRNAdecreases expression 16054898
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000008 Abdominal Neoplasms Tamoxifen 4.6414745880
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.9315322242 11752688 14514962
MESH:D000138 Acidosis Ammonium Chloride 3.6418287403
MESH:D000152 Acne Vulgaris Ethinyl Estradiol 4.0417505938
MESH:D055371 Acute Lung Injury pirinixic acid 3.1718653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 4.2220464547 20127859
MESH:D000230 Adenocarcinoma Ethinyl Estradiol 4.2214692618
MESH:D000236 Adenoma Benzo(a)pyrene 6.736695378
MESH:D000236 Adenoma Diethylnitrosamine 6.736695378 10737359
MESH:D018248 Adenoma, Liver Cell Diethylnitrosamine 17.7816434500 17620307 17162532 18056438 19061943 19052882
MESH:D018248 Adenoma, Liver Cell pirinixic acid 17.7816434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 17.7816835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.0011748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.1519183758
MESH:D001161 Arteriosclerosis Ethinyl Estradiol 3.5411256880
MESH:D001169 Arthritis, Experimental Ethinyl Estradiol 2.6915885639
MESH:D001778 Blood Coagulation Disorders pirinixic acid 8.9519483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.9512125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.8915340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8015746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.9317474063 20146248
MESH:D001943 Breast Neoplasms Diethylnitrosamine 1.9317474063
MESH:D001943 Breast Neoplasms Tamoxifen 1.9319200415 19142967 19084267 17440819 19011961 18997820 18351453 18425577 15668708 16818667 21152245 20390343 18629630 19487384 19155303 19244106 15565566 21138602 19221464 17049068 17261762 20005174 17893378 18821012 20544844 19066611 11161223 20065188 20859285 16873071 19189210 17242785 18815881 18855134 20135344 16273361 19115204 19410462 19189212 19103187 19288272 16202921 19059307 18984771 19289846
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.9320435547
MESH:D002252 Carbon Tetrachloride Poisoning Carbon Tetrachloride 3.8518705752 10355542 16097048 15673190 16124888 15700767 16192424 16227642 16011737 15721981 3786805 16050911
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 2.8416835633
MESH:D018270 Carcinoma, Ductal, Breast Tamoxifen 4.5819066611
MESH:D006528 Carcinoma, Hepatocellular 2,4-dinitrotoluene 8.9616705839
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 8.9612907637 21507988 12619106
MESH:D006528 Carcinoma, Hepatocellular Carbon Tetrachloride 8.9618788625
MESH:D006528 Carcinoma, Hepatocellular Diethylnitrosamine 8.9616830150 19052882 20101231 17173139 20214788 17055752 17162532 19539802 16698587 3084413 18971187 16288022 20512989 10672840 19418558 19208518 19822196 18785209 10737359 18788625 18665156 20514400 20727157 19171122 16540662 20524982 16328049 18393292 11831363 18506893 21159647 20935162 16681979 17978847 18691550 19919837 16569478 19394651 18056438 19701751 16502159 17138121 3581430 20084675 18494052 16878318 20432363 16807293 20007298 17761372 19335982 19519916 19383236 18210153 19107877 17428255 16779866 16935385 18978308
MESH:D006528 Carcinoma, Hepatocellular Tamoxifen 8.9616924424
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.0620419170
MESH:D002295 Carcinoma, Transitional Cell Tamoxifen 3.6617572228
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.3916120746 18670907 18850075
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 6.7312371664
MESH:D002471 Cell Transformation, Neoplastic Diethylnitrosamine 6.7317174075 2727394 7505956 21159647
MESH:D018281 Cholangiocarcinoma Diethylnitrosamine 9.4919052882
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 9.4916835633
MESH:D002779 Cholestasis Cyclosporine 13.5819486331
MESH:D002779 Cholestasis Ethinyl Estradiol 13.5811677210 17681005 17333356 16105132 15861022 16919318 17110522
MESH:D002779 Cholestasis pirinixic acid 13.5819176532
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1212621046 8697196 15668235 16354765 15340226
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.1114669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2615322242 20055451 10048152
MESH:D003490 Cyanosis 2,4-dinitrotoluene 4.0918551238
MESH:D003711 Demyelinating Diseases Tamoxifen 4.4319031437
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.4518249437
MESH:D003924 Diabetes Mellitus, Type 2 Diethylnitrosamine 4.2620387270
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.2617107852
MESH:D003928 Diabetic Nephropathies Tamoxifen 3.5219279558
MESH:D056486 Drug-Induced Liver Injury 2,4-dinitrotoluene 9.0921346803 18551238
MESH:D056486 Drug-Induced Liver Injury Carbon Tetrachloride 9.0911566570 16177239 6884620 4309450 15027814 15998439 2869522 7440962 3732212 17522070 7179309 3786805 10092053 16227642 19336974 6623471 9327722 21278145 10915739 19085960 15968718 7120509
MESH:D056486 Drug-Induced Liver Injury Diethylnitrosamine 9.0919107877
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 9.0920420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.8011462148
MESH:D004487 Edema pirinixic acid 6.7212083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.7211000095 12711302
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.0016714409 15322242 18230668
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Ethinyl Estradiol 9.1612538720
MESH:D004681 Encephalomyelitis, Autoimmune, Experimental Tamoxifen 9.1619031437
MESH:D016889 Endometrial Neoplasms Tamoxifen 3.0817893378 16202921 20544844 19155303
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.079294722 10568697
MESH:D004931 Esophageal Achalasia Diethylnitrosamine 5.2116302075
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0216530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.0511564622
MESH:D005234 Fatty Liver Carbon Tetrachloride 31.5217595544 16045604 12795759 12631006 15959796 61145 16239168 19224547
MESH:D005234 Fatty Liver Cyclosporine 31.5219224547
MESH:D005234 Fatty Liver Diethylnitrosamine 31.5220387270 21071580
MESH:D005234 Fatty Liver Ethinyl Estradiol 31.5215345470
MESH:D005234 Fatty Liver pirinixic acid 31.5220131406 19236843
MESH:D005234 Fatty Liver Tamoxifen 31.5214986274 19224547
MESH:D052776 Female Urogenital Diseases Tamoxifen 3.2716709447
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.5311858732
MESH:D018221 Fibromatosis, Abdominal Tamoxifen 4.6114745880
MESH:D018222 Fibromatosis, Aggressive Tamoxifen 4.2619069698
MESH:D005355 Fibrosis Carbon Tetrachloride 15.1518705752
MESH:D005355 Fibrosis Cyclosporine 15.1512639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 15.1520067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.308708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.6910696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.5420471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.5410048152 11294989
MESH:D006333 Heart Failure pirinixic acid 2.5720558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.5015720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.3911000095
MESH:D006505 Hepatitis Carbon Tetrachloride 3.6619110552 19900420
MESH:D006529 Hepatomegaly pirinixic acid 8.5018467677 19772884 19176532 16221962
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 8.5015340226 12621046 16120746
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.1418606429 15340226 16354765 8697196 16959395
MESH:D006932 Hyperbilirubinemia Carbon Tetrachloride 4.6116899240
MESH:D006943 Hyperglycemia pirinixic acid 3.2320558911
MESH:D006973 Hypertension Cyclosporine 5.0110903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.0118670907 18850075
MESH:D006975 Hypertension, Portal Carbon Tetrachloride 4.1615338365
MESH:D007021 Hypospadias Ethinyl Estradiol 3.8816569931 16945680
MESH:D007247 Infertility, Female Ethinyl Estradiol 3.5212013081
MESH:D007248 Infertility, Male Ethinyl Estradiol 2.5217937319
MESH:D007249 Inflammation Diethylnitrosamine 8.4318785209
MESH:D007249 Inflammation Tamoxifen 8.4319457130
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 8.4312200463 12878042
MESH:D007333 Insulin Resistance pirinixic acid 2.6616306350
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.3916580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.5415604871
MESH:D007674 Kidney Diseases Cyclosporine 2.3718776723 10903974 8314463
MESH:D007680 Kidney Neoplasms 2,4-dinitrotoluene 12.6416705839
MESH:D007680 Kidney Neoplasms Cyclosporine 12.6412371664
MESH:D007680 Kidney Neoplasms Tamoxifen 12.6418625569
MESH:D008064 Lipidoses Tamoxifen 3.1915342952 17567588
MESH:D008103 Liver Cirrhosis Carbon Tetrachloride 6.7017334410 16221502 11903743 16943688 17157831 11408273 16239168 21278145 17174718
MESH:D008103 Liver Cirrhosis Diethylnitrosamine 6.7020032147 18407596 18522880 18665156 19638242
MESH:D008106 Liver Cirrhosis, Experimental Carbon Tetrachloride 4.9718166357 15370692 18205269 15931870 13678700 12666154 17944888 12898905 15123356 17708605 12609069 16638106 17631135 14716496 18395095 15730626 15876570 15893842 17976157 15925388 12586293 18472094 20821823 18054572 17640975 17922224 12445421 15338365 17525996 18006644 12667390 18277467 16011737 15052691 18251166 14512876 18705752 16136751 15057751 12389079 18418968 17869086 15362042 18317297 12632512 14748882 18376398 14620537 17766677 12632514 18263696 15673190 15996030 17761835 15959796 17557913 14724832 12445418 18339082 16015684 18429990 18412020 18187930 18395914 14716833 17481882 17714472 17823541 18279442 17805973 10355542 12546737 17721639 16116963 16027843 18210741 16033810 15650968 16097048 16248980 12741479 12649538 12958196 17698563 17900296 17565644 18481824 18472332 16192424 15818738 18156304 18420326 11481614
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 4.9715474484
MESH:D008106 Liver Cirrhosis, Experimental Tamoxifen 4.9718564211
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 4.9712878042
MESH:D008107 Liver Diseases Carbon Tetrachloride 4.1116964402 15720792 17285989 15830285 16246199
MESH:D008107 Liver Diseases Diethylnitrosamine 4.1117034775
MESH:D017093 Liver Failure Carbon Tetrachloride 4.2415123358
MESH:D017114 Liver Failure, Acute Carbon Tetrachloride 3.7416899240 14706259
MESH:D008113 Liver Neoplasms Aflatoxin B1 26.379163691 18177683 2125692 15890375
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 26.3721137059 20195826
MESH:D008113 Liver Neoplasms Carbon Tetrachloride 26.3719294768
MESH:D008113 Liver Neoplasms Diethylnitrosamine 26.3720501860 20452335 19294768 9163691 2862719 18648771 19642983 19256749 19551842 19426721 2422723 20492335 19255062 12112319 19850985 18754104 20101389 15175105 20434301 19499222 21167192 19812893 19090486 10737359 19833225 19254457 19427195 12771043 18977376 20137499 21071580 18644402 19073162 21278145 19996281 19638242 15885732 19690152 16942905 20405173 21047994 20118626 18978307 20583210
MESH:D008113 Liver Neoplasms Methapyrilene 26.3715890375
MESH:D008113 Liver Neoplasms pirinixic acid 26.3720007298 16377806 15890375
MESH:D008113 Liver Neoplasms Tamoxifen 26.3716684651
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 26.3716984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 14.398603461
MESH:D008114 Liver Neoplasms, Experimental Carbon Tetrachloride 14.3915583823 12014681
MESH:D008114 Liver Neoplasms, Experimental Diethylnitrosamine 14.3916267830 2563599 17942915 16842330 18253720 17854601 18775883 19519916 18079962 18308698 19009564 9362446 19539802 18093689 18164116 18282651 18544905 19004024 19126423 17174075 21159647 3124819
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 14.3912151625
MESH:D008175 Lung Neoplasms Aflatoxin B1 6.6414755239
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 6.6420464547 6695378 20869020 20135361 18569708 18520028 18816296 17053015 20064080
MESH:D008175 Lung Neoplasms Diethylnitrosamine 6.646695378 21163286 20970405 20512841
MESH:D008175 Lung Neoplasms Tamoxifen 6.6418625569
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 6.6411884234 19555203
MESH:D015674 Mammary Neoplasms, Animal Tamoxifen 3.8419428831
MESH:D008325 Mammary Neoplasms, Experimental Corticosterone 6.4712807724
MESH:D008325 Mammary Neoplasms, Experimental Tamoxifen 6.4711731420 16827153 14580682 19196722 19196723
MESH:D020149 Manganese Poisoning Tamoxifen 4.6419453300
MESH:D008545 Melanoma Tamoxifen 1.8912393984 19393235
MESH:D018328 Melanoma, Amelanotic Tamoxifen 4.2615990972
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.8816801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.2316381670
MESH:D009135 Muscular Diseases pirinixic acid 3.5816239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.1619151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.0612213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 2.9916411023
MESH:D009336 Necrosis 2,4-dinitrotoluene 3.9418551238
MESH:D009362 Neoplasm Metastasis Diethylnitrosamine 5.809029167 3581430
MESH:D009362 Neoplasm Metastasis Tamoxifen 5.8019393235
MESH:D009364 Neoplasm Recurrence, Local Tamoxifen 2.5319410462
MESH:D009369 Neoplasms Benzo(a)pyrene 4.9011141357
MESH:D009369 Neoplasms pirinixic acid 4.9017405874
MESH:D009376 Neoplasms, Hormone-Dependent Tamoxifen 4.1019200415 19189210 19196722
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.5417954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.3319348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.2814600291
MESH:D019636 Neurodegenerative Diseases Diethylnitrosamine 3.3920387270
MESH:D009461 Neurologic Manifestations Diethylnitrosamine 5.2120387270
MESH:D009765 Obesity pirinixic acid 1.8220558911
MESH:D009784 Occupational Diseases 2,4-dinitrotoluene 3.4816049721 12819281
MESH:D010190 Pancreatic Neoplasms Diethylnitrosamine 2.4416540662
MESH:D016584 Panic Disorder Ethinyl Estradiol 3.7511578682
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.3512520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.6218163543
MESH:D011230 Precancerous Conditions Cyclosporine 9.1012371664
MESH:D011230 Precancerous Conditions Diethylnitrosamine 9.102563599
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.2711222880 11896295 11118676 11399792
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1217292933
MESH:D011471 Prostatic Neoplasms Tamoxifen 3.1215067354
MESH:D011537 Pruritus Ethinyl Estradiol 3.3916919318 15861022
MESH:D011565 Psoriasis Cyclosporine 2.2416882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.4119058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.9018990726
MESH:D012640 Seizures 2,4-dinitrotoluene 2.5718551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.5519755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.5516192470
MESH:D013088 Spermatocele Ethinyl Estradiol 11.8916709447
MESH:D013088 Spermatocele Tamoxifen 11.8916709447
MESH:D013119 Spinal Cord Injuries Tamoxifen 4.1219457130
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 2.342093021 20155912
MESH:D013274 Stomach Neoplasms Diethylnitrosamine 2.3418456281
MESH:D019851 Thrombophilia Ethinyl Estradiol 3.6811994571
MESH:D013927 Thrombosis Ethinyl Estradiol 3.2015669648
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.0012697716
MESH:D013964 Thyroid Neoplasms Diethylnitrosamine 3.027505956
MESH:D001749 Urinary Bladder Neoplasms 2,4-dinitrotoluene 8.3916049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 8.3917053015
MESH:D001749 Urinary Bladder Neoplasms Tamoxifen 8.3916712894 8653321 17572228
MESH:D014571 Urologic Neoplasms 2,4-dinitrotoluene 4.4010091137
MESH:D014594 Uterine Neoplasms Ethinyl Estradiol 3.3614692618
MESH:D014605 Uveitis Cyclosporine 4.081336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.6912125929
MESH:D020246 Venous Thrombosis Ethinyl Estradiol 3.5915869587 14671159
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.3515886252
MESH:D014985 Xerophthalmia Cyclosporine 4.5417120751
Pathway ID Pathway Name
KEGG:00480 Glutathione metabolism
Pharmacogenomics Knowledge Base Top
Drug Bank Top
Drugbank ID Action Drug Name Description
DB00142 - L-Glutamic Acid Dietary supplement;Micronutrient;Non-Essential Amino Acids
No data
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Simple Query:


  (e.g. CHD8)

Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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