Annotation Detail for GH1
Basic Information Top
| Gene Symbol: | GH1 ( GH,GH-N,GHN,IGHD1B,hGH-N ) |
|---|---|
| Gene Full Name: | growth hormone 1 |
| Band: | 17q23.3 |
| Quick Links | Entrez ID:2688; OMIM: 139250; Uniprot ID:SOMA_HUMAN; ENSEMBL ID: ENSG00000189162; HGNC ID: 4261 |
| Relate to Another Database: | SFARIGene; denovo-db |
| No data |
| Desease ID | Desease Name |
|---|---|
| 1738 | Cushing syndrome |
| 1740 | Alzheimer's disease |
| 1809 | HIV infection |
| 1821 | Spinal cord disease |
| 1848 | Embryoma |
| 1856 | Obesity |
| 1901 | Endometriosis |
| 1904 | Diabetes mellitus |
| 1940 | Ovarian disease |
| 1944 | Breast cancer |
| 1978 | Cholestasis |
| 1986 | Eating disorder |
| 2001 | Mental retardation |
| 2007 | Liver tumor |
| 2021 | Acromegaly |
| 2022 | Liver cancer |
| 2031 | Endometrial cancer |
| 2091 | Hypertension |
| 2102 | Polycystic ovary syndrome |
| 2138 | Osteoporosis |
| 2169 | Pituitary tumor |
| 2238 | Lipodystrophy |
| Desease Name |
|---|
| colorectal cancer |
| bone mass |
| CANCER |
| intrauterine growth |
| breast cancer |
| METABOLIC |
| growth hormone secretion and height |
| REPRODUCTION |
| colorectal neoplasia. |
| No data |
| Desease Name |
|---|
| Kowarski syndrome |
| Growth hormone deficiency, isolated, type II |
| Growth hormone deficiency, isolated, type IA |
| Growth hormone deficiency, isolated, type IB |
| Chemical ID | Chemical Name | Interaction | Interaction Action | Publication |
|---|---|---|---|---|
| C025603 | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| C025603 | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| C043958 | 2-butanol | 2-butanol affects the folding of GH1 protein | affects folding | 11064379 |
| C016601 | 4-hydroxytamoxifen | 4-hydroxytamoxifen promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] | increases phosphorylation|increases reaction | 17272397 |
| C041594 | 4-nonylphenol | 4-nonylphenol results in increased expression of GH1 mRNA | increases expression | 19145065 19463694 |
| C041594 | 4-nonylphenol | 4-nonylphenol results in increased expression of GH1 protein | increases expression | 19145065 |
| C041594 | 4-nonylphenol | 4-nonylphenol results in increased secretion of GH1 protein | increases secretion | 19463694 |
| C041594 | 4-nonylphenol | fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 19145065 |
| C041594 | 4-nonylphenol | fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C041594 | 4-nonylphenol | fulvestrant inhibits the reaction [4-nonylphenol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C080417 | 4-octylphenol | 4-octylphenol results in increased expression of GH1 mRNA | increases expression | 19463694 |
| C080417 | 4-octylphenol | 4-octylphenol results in increased secretion of GH1 protein | increases secretion | 19463694 |
| C080417 | 4-octylphenol | fulvestrant inhibits the reaction [4-octylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| C080417 | 4-octylphenol | fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C105260 | 4-tert-octylphenol | 4-tert-octylphenol results in increased expression of GH1 mRNA | increases expression | 19145065 |
| C105260 | 4-tert-octylphenol | 4-tert-octylphenol results in increased expression of GH1 protein | increases expression | 19145065 |
| C105260 | 4-tert-octylphenol | fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19145065 |
| C105260 | 4-tert-octylphenol | fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C103303 | alitretinoin | alitretinoin results in increased expression of GH1 mRNA | increases expression | 17090972 |
| C095512 | alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide | alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide inhibits the reaction [GH1 protein results in increased phosphorylation of STAT5A protein] | decreases reaction|increases phosphorylation | 18388193 |
| C011512 | alpha-naphthoflavone | [Tetrachlorodibenzodioxin co-treated with alpha-naphthoflavone] affects the expression of GH1 mRNA | affects cotreatment|affects expression | 16188257 |
| D006710 | Homocysteine | GH1 protein results in decreased abundance of Homocysteine | decreases abundance | 17311540 17324600 |
| D000638 | Amiodarone | Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 2910914 |
| D000643 | Ammonium Chloride | Ammonium Chloride affects the expression of GH1 mRNA | affects expression | 16483693 |
| C006780 | bisphenol A | [bisphenol A co-treated with GH1 protein] results in increased activity of GHR1 protein | affects cotreatment|increases activity | 20467862 |
| C006780 | bisphenol A | [bisphenol A co-treated with GH1 protein] results in increased activity of GHR2 protein | affects cotreatment|increases activity | 20467862 |
| C006780 | bisphenol A | ESR1 protein inhibits the reaction [[bisphenol A co-treated with GH1 protein] results in increased activity of GHR1 protein] | affects cotreatment|decreases reaction|increases activity | 20467862 |
| C006780 | bisphenol A | ESR1 protein inhibits the reaction [[bisphenol A co-treated with GH1 protein] results in increased activity of GHR2 protein] | affects cotreatment|decreases reaction|increases activity | 20467862 |
| C006780 | bisphenol A | bisphenol A results in increased expression of GH1 mRNA | increases expression | 19463694 |
| C006780 | bisphenol A | bisphenol A results in increased expression of GH1 protein | increases expression | 19145065 |
| C006780 | bisphenol A | bisphenol A results in increased secretion of GH1 protein | increases secretion | 19463694 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C006780 | bisphenol A | fulvestrant inhibits the reaction [bisphenol A results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| D020001 | 1-Butanol | 1-Butanol affects the folding of GH1 protein | affects folding | 11064379 |
| D019256 | Cadmium Chloride | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | Genistein inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | Genistein inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA] | increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA] | increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | GH1 protein promotes the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein] | increases phosphorylation|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | GH1 protein promotes the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein] | increases phosphorylation|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | GH1 protein promotes the reaction [Cadmium Chloride results in increased phosphorylation of STAT5 protein] | increases phosphorylation|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | Thapsigargin inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019256 | Cadmium Chloride | Thapsigargin inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D002110 | Caffeine | GH1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of Caffeine] | increases metabolic processing|increases reaction | 11907490 |
| C033394 | CGP 12177 | GH1 protein promotes the reaction [CGP 12177 results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| D002712 | Chlorides | GH1 protein affects the transport of [Sodium co-treated with Chlorides] | affects cotreatment|affects transport | 18388193 |
| D002712 | Chlorides | pegvisomant inhibits the reaction [GH1 protein results in increased transport of [Sodium co-treated with Chlorides]] | affects cotreatment|decreases reaction|increases transport | 18388193 |
| D003907 | Dexamethasone | Dexamethasone results in decreased expression of GH1 protein | decreases expression | 12670838 |
| C068327 | diallyl sulfone | GH1 protein inhibits the reaction [diallyl sulfone results in increased expression of CYP2B1 mRNA] | decreases reaction|increases expression | 8390837 |
| C068327 | diallyl sulfone | GH1 protein inhibits the reaction [diallyl sulfone results in increased expression of CYP2B2 mRNA] | decreases reaction|increases expression | 8390837 |
| D003633 | Dichlorodiphenyl Dichloroethylene | Dichlorodiphenyl Dichloroethylene results in decreased expression of GH1 mRNA | decreases expression | 17056472 |
| D004041 | Dietary Fats | Dietary Fats results in decreased expression of GH1 mRNA | decreases expression | 18721800 |
| D002117 | Calcitriol | GH1 protein affects the reaction [CYP27B1 protein affects the abundance of Calcitriol] | affects abundance|affects reaction | 11316734 |
| D015127 | 9,10-Dimethyl-1,2-benzanthracene | GH1 gene mutant form results in decreased susceptibility to 9,10-Dimethyl-1,2-benzanthracene | decreases response to substance | 12082019 |
| D004221 | Disulfiram | GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B1 mRNA] | decreases reaction|increases expression | 8390837 |
| D004221 | Disulfiram | GH1 protein inhibits the reaction [Disulfiram results in increased expression of CYP2B2 mRNA] | decreases reaction|increases expression | 8390837 |
| D004280 | Dobutamine | GH1 protein promotes the reaction [Dobutamine results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| D004958 | Estradiol | [Estradiol co-treated with Progesterone] inhibits the reaction [GH1 protein results in increased susceptibility to Methylnitrosourea] | affects cotreatment|decreases reaction|increases response to substance | 15528971 |
| D004958 | Estradiol | Estradiol inhibits the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] | decreases reaction|increases phosphorylation | 17272397 |
| D004958 | Estradiol | [Progesterone co-treated with Estradiol] results in increased secretion of GH1 protein | affects cotreatment|increases secretion | 15772906 |
| D004958 | Estradiol | Estradiol results in increased expression of GH1 mRNA | increases expression | 16188257 17823450 |
| D004958 | Estradiol | Estradiol results in increased expression of GH1 mRNA | increases expression | 19463694 |
| D004958 | Estradiol | Estradiol results in increased expression of GH1 protein | increases expression | 15860553 11408345 |
| D004958 | Estradiol | Estradiol results in increased secretion of GH1 protein | increases secretion | 19463694 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| D004958 | Estradiol | fulvestrant inhibits the reaction [Estradiol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C015854 | estradiol valerate | estradiol valerate results in increased expression of GH1 protein | increases expression | 10843175 |
| D004966 | Estrogens, Conjugated (USP) | Estrogens, Conjugated (USP) results in increased expression of GH1 protein | increases expression | 10843175 |
| D000431 | Ethanol | Ethanol affects the folding of GH1 protein | affects folding | 11064379 |
| D004997 | Ethinyl Estradiol | [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of GH1 protein | affects cotreatment|increases expression | 11172797 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of GH1 protein | increases expression | 10843175 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in decreased expression of GH1 mRNA | decreases expression | 18000313 |
| D004997 | Ethinyl Estradiol | Ethinyl Estradiol results in increased expression of GH1 mRNA | increases expression | 17222921 |
| C004912 | ethylbenzene | GH1 protein inhibits the reaction [ethylbenzene results in increased expression of CYP2E1 protein] | decreases reaction|increases expression | 11884239 |
| D019855 | Ethylene Glycol | Ethylene Glycol affects the folding of GH1 protein | affects folding | 11064379 |
| D005485 | Flutamide | Flutamide results in increased expression of GH1 mRNA | increases expression | 17222921 |
| D005576 | Forskolin | GH1 protein promotes the reaction [Forskolin results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| C070081 | fulvestrant | fulvestrant results in increased expression of GH1 mRNA | increases expression | 16188257 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 19145065 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-nonylphenol results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-nonylphenol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-octylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-octylphenol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19145065 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [4-tert-octylphenol results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in increased expression of GH1 protein] | decreases reaction|increases expression | 19145065 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [bisphenol A results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 19463694 |
| C070081 | fulvestrant | fulvestrant inhibits the reaction [Estradiol results in increased secretion of GH1 protein] | decreases reaction|increases secretion | 19463694 |
| D019833 | Genistein | Genistein inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019833 | Genistein | Genistein inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D008055 | Lipids | GH1 protein promotes the reaction [CGP 12177 results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| D008055 | Lipids | GH1 protein promotes the reaction [Dobutamine results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| D008055 | Lipids | GH1 protein promotes the reaction [Forskolin results in increased metabolism of Lipids] | increases metabolic processing|increases reaction | 14981226 |
| C005095 | malachite green | ESR1 protein inhibits the reaction [[malachite green co-treated with GH1 protein] results in increased activity of GHR1 protein] | affects cotreatment|decreases reaction|increases activity | 20467862 |
| C005095 | malachite green | ESR1 protein inhibits the reaction [[malachite green co-treated with GH1 protein] results in increased activity of GHR2 protein] | affects cotreatment|decreases reaction|increases activity | 20467862 |
| C005095 | malachite green | [malachite green co-treated with GH1 protein] results in increased activity of GHR1 protein | affects cotreatment|increases activity | 20467862 |
| C005095 | malachite green | [malachite green co-treated with GH1 protein] results in increased activity of GHR2 protein | affects cotreatment|increases activity | 20467862 |
| D008617 | Mephenytoin | GH1 protein inhibits the reaction [CYP2C19 protein results in increased metabolism of Mephenytoin] | decreases reaction|increases metabolic processing | 11907490 |
| D008770 | Methylnitrosourea | [Estradiol co-treated with Progesterone] inhibits the reaction [GH1 protein results in increased susceptibility to Methylnitrosourea] | affects cotreatment|decreases reaction|increases response to substance | 15528971 |
| D008770 | Methylnitrosourea | GH1 protein results in increased susceptibility to Methylnitrosourea | increases response to substance | 15528971 |
| D008770 | Methylnitrosourea | GH1 gene mutant form results in decreased susceptibility to Methylnitrosourea | decreases response to substance | 12082019 |
| D016912 | Levonorgestrel | [Ethinyl Estradiol co-treated with Levonorgestrel] results in increased expression of GH1 protein | affects cotreatment|increases expression | 11172797 |
| C016340 | o,p'-DDT | o,p'-DDT results in increased expression of GH1 mRNA | increases expression | 16188257 |
| C406545 | pegvisomant | pegvisomant inhibits the reaction [GH1 protein results in increased phosphorylation of STAT5A protein] | decreases reaction|increases phosphorylation | 18388193 |
| C406545 | pegvisomant | pegvisomant inhibits the reaction [GH1 protein results in increased transport of [Sodium co-treated with Chlorides]] | affects cotreatment|decreases reaction|increases transport | 18388193 |
| D026023 | Permethrin | GH1 protein inhibits the reaction [Permethrin results in increased expression of CYP2B1 mRNA] | decreases reaction|increases expression | 14722249 |
| D010634 | Phenobarbital | GH1 protein inhibits the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA] | decreases reaction|increases expression | 14722249 |
| D011374 | Progesterone | [Estradiol co-treated with Progesterone] inhibits the reaction [GH1 protein results in increased susceptibility to Methylnitrosourea] | affects cotreatment|decreases reaction|increases response to substance | 15528971 |
| D011374 | Progesterone | [Progesterone co-treated with Estradiol] results in increased secretion of GH1 protein | affects cotreatment|increases secretion | 15772906 |
| D011374 | Progesterone | Progesterone results in increased secretion of GH1 protein | increases secretion | 15772906 |
| D011374 | Progesterone | GH1 protein promotes the reaction [Progesterone results in increased expression of STC1 mRNA] | increases expression|increases reaction | 16452456 |
| D019946 | Propylene Glycol | Propylene Glycol affects the folding of GH1 protein | affects folding | 11064379 |
| D019840 | 2-Propanol | 2-Propanol affects the folding of GH1 protein | affects folding | 11064379 |
| D000433 | 1-Propanol | 1-Propanol affects the folding of GH1 protein | affects folding | 11064379 |
| D020849 | Raloxifene | Raloxifene promotes the reaction [GH1 protein results in increased phosphorylation of JAK2 protein] | increases phosphorylation|increases reaction | 17272397 |
| D012964 | Sodium | GH1 protein results in increased abundance of Sodium | increases abundance | 17311540 17324600 |
| D012964 | Sodium | GH1 protein affects the transport of Sodium | affects transport | 18388193 |
| D012964 | Sodium | GH1 protein affects the transport of [Sodium co-treated with Chlorides] | affects cotreatment|affects transport | 18388193 |
| D012964 | Sodium | [GH1 protein co-treated with IGF1 protein] affects the transport of Sodium | affects cotreatment|affects transport | 18388193 |
| D012964 | Sodium | pegvisomant inhibits the reaction [GH1 protein results in increased transport of [Sodium co-treated with Chlorides]] | affects cotreatment|decreases reaction|increases transport | 18388193 |
| D014284 | Triiodothyronine | Amiodarone inhibits the reaction [Triiodothyronine results in increased expression of GH1 mRNA] | decreases reaction|increases expression | 2910914 |
| D014284 | Triiodothyronine | Triiodothyronine results in increased expression of GH1 mRNA | increases expression | 2910914 17090972 |
| D013974 | Thyroxine | GH1 protein results in decreased abundance of Thyroxine | decreases abundance | 17311540 17324600 |
| D020002 | tert-Butyl Alcohol | tert-Butyl Alcohol affects the folding of GH1 protein | affects folding | 11064379 |
| D013749 | Tetrachlorodibenzodioxin | [Tetrachlorodibenzodioxin co-treated with alpha-naphthoflavone] affects the expression of GH1 mRNA | affects cotreatment|affects expression | 16188257 |
| D013749 | Tetrachlorodibenzodioxin | Tetrachlorodibenzodioxin results in increased expression of GH1 mRNA | increases expression | 16188257 |
| D019284 | Thapsigargin | Thapsigargin inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNA mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D019284 | Thapsigargin | Thapsigargin inhibits the reaction [GH1 protein promotes the reaction [Cadmium Chloride results in increased expression of MTNB mRNA]] | decreases reaction|increases expression|increases reaction | 17027146 |
| D013853 | Thioacetamide | GH1 protein affects the susceptibility to Thioacetamide | affects response to substance | 11255791 |
| D014212 | Tretinoin | Tretinoin affects the expression of GH1 protein | affects expression | 1630583 |
| D014212 | Tretinoin | Tretinoin results in increased expression of GH1 mRNA | increases expression | 17090972 |
| D014270 | Trifluoroethanol | Trifluoroethanol affects the folding of GH1 protein | affects folding | 11064379 |
| D014801 | Vitamin A | GH1 protein promotes the reaction [Vitamin A affects the expression of and affects the activity of CYP2C11 protein] | affects activity|affects expression|increases reaction | 15963505 |
| Disease ID | Disease Name | Direct Evidence | Inference Chemical Name | Inference Score | Publication |
|---|---|---|---|---|---|
| MESH:D000014 | Abnormalities, Drug-Induced | Disulfiram | 15.33 | 17676605 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Ethanol | 15.33 | 18926900 17676605 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Phenobarbital | 15.33 | 6195326 | |
| MESH:D000014 | Abnormalities, Drug-Induced | Tetrachlorodibenzodioxin | 15.33 | 15322242 14514962 11752688 | |
| MESH:D000015 | Abnormalities, Multiple | Vitamin A | 4.30 | 10992263 | |
| MESH:D000138 | Acidosis | Ammonium Chloride | 8.40 | 18287403 | |
| MESH:D000138 | Acidosis | Ethanol | 8.40 | 11192467 | |
| MESH:D000152 | Acne Vulgaris | Ethinyl Estradiol | 3.31 | 17505938 | |
| MESH:D000163 | Acquired Immunodeficiency Syndrome | Disulfiram | 4.94 | 9207937 | |
| MESH:D000172 | Acromegaly | marker/mechanism | 18388193 | ||
| MESH:D058186 | Acute Kidney Injury | Ethylene Glycol | 5.77 | 6499799 | |
| MESH:D000230 | Adenocarcinoma | 9,10-Dimethyl-1,2-benzanthracene | 11.36 | 10697514 12844480 | |
| MESH:D000230 | Adenocarcinoma | Estradiol | 11.36 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Ethinyl Estradiol | 11.36 | 14692618 | |
| MESH:D000230 | Adenocarcinoma | Genistein | 11.36 | 11473722 | |
| MESH:D000230 | Adenocarcinoma | Methylnitrosourea | 11.36 | 15688392 15113128 | |
| MESH:D000236 | Adenoma | 9,10-Dimethyl-1,2-benzanthracene | 4.17 | 11376689 | |
| MESH:D018248 | Adenoma, Liver Cell | Phenobarbital | 8.01 | 17620307 | |
| MESH:D018248 | Adenoma, Liver Cell | Tetrachlorodibenzodioxin | 8.01 | 16835633 | |
| MESH:D000382 | Agricultural Workers' Diseases | Dichlorodiphenyl Dichloroethylene | 4.19 | 16487989 | |
| MESH:D000419 | Albuminuria | Raloxifene | 4.00 | 17451421 17308373 | |
| MESH:D020268 | Alcohol-Induced Disorders, Nervous System | Ethanol | 4.68 | 15451040 15451039 | |
| MESH:D000437 | Alcoholism | Disulfiram | 4.48 | 17079463 18968458 10841824 | |
| MESH:D000505 | Alopecia | Tretinoin | 3.11 | 15955085 | |
| MESH:D000544 | Alzheimer Disease | Raloxifene | 2.38 | 15800139 | |
| MESH:D000740 | Anemia | Tetrachlorodibenzodioxin | 7.16 | 11748828 | |
| MESH:D000740 | Anemia | Vitamin A | 7.16 | 16960172 | |
| MESH:D018798 | Anemia, Iron-Deficiency | Vitamin A | 4.25 | 16960172 | |
| MESH:D000853 | Anophthalmos | Ethanol | 4.21 | 15513904 | |
| MESH:D001008 | Anxiety Disorders | Ethanol | 3.50 | 11141031 | |
| MESH:D001145 | Arrhythmias, Cardiac | Amiodarone | 3.26 | 18218290 20041841 18057881 | |
| MESH:D001161 | Arteriosclerosis | Dietary Fats | 7.89 | 15238619 | |
| MESH:D001161 | Arteriosclerosis | Ethinyl Estradiol | 7.89 | 11256880 | |
| MESH:D001169 | Arthritis, Experimental | Dexamethasone | 9.87 | 17659584 | |
| MESH:D001169 | Arthritis, Experimental | Ethinyl Estradiol | 9.87 | 15885639 | |
| MESH:D001169 | Arthritis, Experimental | Tretinoin | 9.87 | 16412693 | |
| MESH:D001172 | Arthritis, Rheumatoid | Tretinoin | 2.09 | 16292516 | |
| MESH:D001249 | Asthma | Tretinoin | 4.42 | 16456186 | |
| MESH:D001249 | Asthma | Vitamin A | 4.42 | 16732791 | |
| MESH:D001259 | Ataxia | 1-Butanol | 5.00 | 7820390 | |
| MESH:D001281 | Atrial Fibrillation | Amiodarone | 3.42 | 18651412 19698954 | |
| MESH:D001284 | Atrophy | fulvestrant | 4.25 | 11514358 | |
| MESH:D001321 | Autistic Disorder | Homocysteine | 3.13 | 20468076 16297937 | |
| MESH:D001471 | Barrett Esophagus | Tretinoin | 3.81 | 16935849 | |
| MESH:D001778 | Blood Coagulation Disorders | Amiodarone | 17.41 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tetrachlorodibenzodioxin | 17.41 | 12125929 | |
| MESH:D001778 | Blood Coagulation Disorders | Thioacetamide | 17.41 | 19483382 | |
| MESH:D001778 | Blood Coagulation Disorders | Tretinoin | 17.41 | 16206674 16197459 | |
| MESH:D001836 | Body Weight Changes | Tetrachlorodibenzodioxin | 3.15 | 15340226 | |
| MESH:D001848 | Bone Diseases, Developmental | Tetrachlorodibenzodioxin | 2.34 | 15746008 | |
| MESH:D001862 | Bone Resorption | bisphenol A | 3.30 | 11985600 | |
| MESH:D020201 | Brain Hemorrhage, Traumatic | Progesterone | 4.70 | 17868700 | |
| MESH:D001930 | Brain Injuries | Progesterone | 8.94 | 15665606 15380490 15845082 | |
| MESH:D001930 | Brain Injuries | Raloxifene | 8.94 | 16580743 | |
| MESH:D001943 | Breast Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 12.63 | 20435547 18840765 16153821 15565634 17127718 | |
| MESH:D001943 | Breast Neoplasms | alitretinoin | 12.63 | 16344269 | |
| MESH:D001943 | Breast Neoplasms | bisphenol A | 12.63 | 17123778 | |
| MESH:D001943 | Breast Neoplasms | Calcitriol | 12.63 | 11237771 | |
| MESH:D001943 | Breast Neoplasms | Dichlorodiphenyl Dichloroethylene | 12.63 | 15061365 | |
| MESH:D001943 | Breast Neoplasms | Dietary Fats | 12.63 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Disulfiram | 12.63 | 17026967 | |
| MESH:D001943 | Breast Neoplasms | Estradiol | 12.63 | 17289903 16675129 12948864 17018787 17261762 14630087 19861407 18497071 | |
| MESH:D001943 | Breast Neoplasms | fulvestrant | 12.63 | 18984771 | |
| MESH:D001943 | Breast Neoplasms | Genistein | 12.63 | 17200150 16873071 16541309 | |
| MESH:D001943 | Breast Neoplasms | Methylnitrosourea | 12.63 | 16253758 11306469 14633655 | |
| MESH:D001943 | Breast Neoplasms | Progesterone | 12.63 | 15562024 17614352 16175315 | |
| MESH:D001943 | Breast Neoplasms | Raloxifene | 12.63 | 17242785 15758505 15775269 17893378 17440819 16912660 17595753 15572757 16837676 17261762 17049068 17952589 | |
| MESH:D001943 | Breast Neoplasms | Tetrachlorodibenzodioxin | 12.63 | 20435547 | |
| MESH:D001943 | Breast Neoplasms | Tretinoin | 12.63 | 16166294 16873071 16443354 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Tretinoin | 10.94 | 16813970 | |
| MESH:D001997 | Bronchopulmonary Dysplasia | Vitamin A | 10.94 | 17377406 17426644 | |
| MESH:D002056 | Burns | Ethanol | 4.04 | 16374292 | |
| MESH:D002177 | Candidiasis | Disulfiram | 5.23 | 15325261 | |
| MESH:D002181 | Candidiasis, Vulvovaginal | Estradiol | 3.84 | 16111702 | |
| MESH:D002277 | Carcinoma | Disulfiram | 6.96 | 17026967 | |
| MESH:D002277 | Carcinoma | Tetrachlorodibenzodioxin | 6.96 | 16835633 | |
| MESH:D018236 | Carcinoma, Embryonal | Tretinoin | 4.52 | 16168501 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Estradiol | 11.90 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Ethanol | 11.90 | 15289165 15763234 18788625 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Genistein | 11.90 | 16924424 | |
| MESH:D006528 | Carcinoma, Hepatocellular | malachite green | 11.90 | 12616621 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Phenobarbital | 11.90 | 17173139 20007298 6705139 20935162 1701930 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Thioacetamide | 11.90 | 17997003 | |
| MESH:D006528 | Carcinoma, Hepatocellular | Tretinoin | 11.90 | 1917145 | |
| MESH:D002278 | Carcinoma in Situ | bisphenol A | 4.36 | 17123778 | |
| MESH:D002289 | Carcinoma, Non-Small-Cell Lung | Disulfiram | 3.66 | 17026967 | |
| MESH:D002294 | Carcinoma, Squamous Cell | 9,10-Dimethyl-1,2-benzanthracene | 6.45 | 11376689 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Calcitriol | 6.45 | 11237771 | |
| MESH:D002294 | Carcinoma, Squamous Cell | Tretinoin | 6.45 | 16096774 16051514 | |
| MESH:D002295 | Carcinoma, Transitional Cell | Raloxifene | 3.53 | 17572228 | |
| MESH:D006332 | Cardiomegaly | Ethanol | 9.35 | 19332462 | |
| MESH:D006332 | Cardiomegaly | Tetrachlorodibenzodioxin | 9.35 | 18850075 18670907 16120746 | |
| MESH:D006332 | Cardiomegaly | Thyroxine | 9.35 | 18093424 | |
| MESH:D002311 | Cardiomyopathy, Dilated | Amiodarone | 2.64 | 15710769 19225199 | |
| MESH:D002318 | Cardiovascular Diseases | therapeutic | 17324600 | ||
| MESH:D002318 | Cardiovascular Diseases | Genistein | 6.00 | 16332659 | |
| MESH:D002318 | Cardiovascular Diseases | Raloxifene | 6.00 | 15775269 | |
| MESH:D002341 | Carotid Artery Thrombosis | Amiodarone | 4.46 | 18974383 | |
| MESH:D002386 | Cataract | Disulfiram | 10.36 | 17936468 15003327 | |
| MESH:D002386 | Cataract | Methylnitrosourea | 10.36 | 12484553 | |
| MESH:D002386 | Cataract | Tretinoin | 10.36 | 17460283 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Estradiol | 5.55 | 18566989 | |
| MESH:D002471 | Cell Transformation, Neoplastic | Methylnitrosourea | 5.55 | 7505956 2727394 | |
| MESH:D002493 | Central Nervous System Diseases | Phenobarbital | 3.64 | 4080065 | |
| MESH:D018290 | Cervical Intraepithelial Neoplasia | Tretinoin | 3.96 | 16129372 | |
| MESH:D015362 | Child Nutrition Disorders | Vitamin A | 4.84 | 16153327 | |
| MESH:D018281 | Cholangiocarcinoma | Tetrachlorodibenzodioxin | 7.77 | 16835633 | |
| MESH:D018281 | Cholangiocarcinoma | Thioacetamide | 7.77 | 18291259 | |
| MESH:D002779 | Cholestasis | Ethinyl Estradiol | 11.05 | 17681005 11677210 16105132 17333356 16919318 15861022 17110522 | |
| MESH:D002779 | Cholestasis | Levonorgestrel | 11.05 | 15861022 | |
| MESH:D002779 | Cholestasis | Vitamin A | 11.05 | 16175620 | |
| MESH:D002822 | Choriocarcinoma | Tretinoin | 4.52 | 16461808 | |
| MESH:D016770 | Ciliophora Infections | malachite green | 5.17 | 16175963 15900690 | |
| MESH:D002971 | Cleft Lip | Ethanol | 3.22 | 15513904 | |
| MESH:D002972 | Cleft Palate | Ethanol | 11.60 | 15513904 | |
| MESH:D002972 | Cleft Palate | Tetrachlorodibenzodioxin | 11.60 | 12621046 8697196 15668235 15340226 16354765 | |
| MESH:D002972 | Cleft Palate | Tretinoin | 11.60 | 9407595 | |
| MESH:D002972 | Cleft Palate | Vitamin A | 11.60 | 16054864 | |
| MESH:D019970 | Cocaine-Related Disorders | Disulfiram | 5.12 | 19462300 | |
| MESH:D003072 | Cognition Disorders | Raloxifene | 4.01 | 15800139 | |
| MESH:D003092 | Colitis | Tretinoin | 3.10 | 17035595 | |
| MESH:D003110 | Colonic Neoplasms | Dexamethasone | 5.07 | 15824018 | |
| MESH:D003110 | Colonic Neoplasms | Genistein | 5.07 | 17182828 | |
| MESH:D003110 | Colonic Neoplasms | Vitamin A | 5.07 | 17219422 16267017 | |
| MESH:D000013 | Congenital Abnormalities | Tetrachlorodibenzodioxin | 2.53 | 14669216 17141729 | |
| MESH:D003324 | Coronary Artery Disease | Homocysteine | 3.50 | 16379339 | |
| MESH:D019465 | Craniofacial Abnormalities | Dexamethasone | 8.16 | 17728286 | |
| MESH:D019465 | Craniofacial Abnormalities | Ethanol | 8.16 | 11873399 15451039 11198716 19302082 15513904 10194807 15451040 | |
| MESH:D019465 | Craniofacial Abnormalities | Permethrin | 8.16 | 19861644 | |
| MESH:D019465 | Craniofacial Abnormalities | Tetrachlorodibenzodioxin | 8.16 | 15322242 10048152 20055451 | |
| MESH:D019465 | Craniofacial Abnormalities | Tretinoin | 8.16 | 9664655 16925845 14991402 17551590 9211117 10589399 9142499 9125849 9224671 8800419 | |
| MESH:D019465 | Craniofacial Abnormalities | Vitamin A | 8.16 | 10992263 | |
| MESH:D003865 | Depressive Disorder, Major | Raloxifene | 3.63 | 17474826 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Dexamethasone | 6.07 | 12438553 | |
| MESH:D017449 | Dermatitis, Allergic Contact | Propylene Glycol | 6.07 | 16191021 | |
| MESH:D003877 | Dermatitis, Contact | Permethrin | 4.42 | 14617103 | |
| MESH:D003922 | Diabetes Mellitus, Type 1 | Vitamin A | 3.28 | 16506275 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Genistein | 3.67 | 16647724 | |
| MESH:D003924 | Diabetes Mellitus, Type 2 | Tetrachlorodibenzodioxin | 3.67 | 17107852 | |
| MESH:D003928 | Diabetic Nephropathies | Estradiol | 7.24 | 19279558 | |
| MESH:D003928 | Diabetic Nephropathies | Raloxifene | 7.24 | 17308373 17451421 15920148 | |
| MESH:D003929 | Diabetic Neuropathies | Progesterone | 3.88 | 17187935 | |
| MESH:D003967 | Diarrhea | Dexamethasone | 3.12 | 7237001 | |
| MESH:D056486 | Drug-Induced Liver Injury | Amiodarone | 9.58 | 18218290 15265979 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethanol | 9.58 | 11566570 | |
| MESH:D056486 | Drug-Induced Liver Injury | Ethylene Glycol | 9.58 | 6499799 | |
| MESH:D056486 | Drug-Induced Liver Injury | Tetrachlorodibenzodioxin | 9.58 | 20420201 | |
| MESH:D056486 | Drug-Induced Liver Injury | Thioacetamide | 9.58 | 12963478 | |
| MESH:D004362 | Drug Toxicity | Tetrachlorodibenzodioxin | 2.29 | 11462148 | |
| MESH:D015352 | Dry Eye Syndromes | Vitamin A | 5.18 | 16146918 | |
| MESH:D050171 | Dyslipidemias | Dietary Fats | 2.99 | 18367378 | |
| MESH:D004417 | Dyspnea | Dichlorodiphenyl Dichloroethylene | 4.63 | 16487989 | |
| MESH:D004421 | Dystonia | Phenobarbital | 3.43 | 1851702 | |
| MESH:C538011 | Eales disease | Vitamin A | 4.98 | 9068938 | |
| MESH:D004480 | Ectromelia | Vitamin A | 5.18 | 16054864 | |
| MESH:D004485 | Eczema | Dexamethasone | 3.87 | 12438553 | |
| MESH:D004487 | Edema | Dexamethasone | 8.36 | 19703484 | |
| MESH:D004487 | Edema | Raloxifene | 8.36 | 15860553 | |
| MESH:D004487 | Edema | Tetrachlorodibenzodioxin | 8.36 | 11000095 12711302 | |
| MESH:D004489 | Edema, Cardiac | Tetrachlorodibenzodioxin | 9.83 | 18230668 15322242 16714409 | |
| MESH:D004489 | Edema, Cardiac | Tretinoin | 9.83 | 18230668 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Calcitriol | 17.09 | 15138306 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Ethinyl Estradiol | 17.09 | 12538720 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Progesterone | 17.09 | 17692515 | |
| MESH:D004681 | Encephalomyelitis, Autoimmune, Experimental | Raloxifene | 17.09 | 15845917 | |
| MESH:D004714 | Endometrial Hyperplasia | Genistein | 3.96 | 16402032 | |
| MESH:D016889 | Endometrial Neoplasms | 4-hydroxytamoxifen | 14.27 | 19148513 | |
| MESH:D016889 | Endometrial Neoplasms | Estradiol | 14.27 | 19148513 11473722 18566989 | |
| MESH:D016889 | Endometrial Neoplasms | Genistein | 14.27 | 11473722 | |
| MESH:D016889 | Endometrial Neoplasms | Tretinoin | 14.27 | 16569247 | |
| MESH:D004715 | Endometriosis | Progesterone | 7.11 | 16134523 | |
| MESH:D004715 | Endometriosis | Tetrachlorodibenzodioxin | 7.11 | 10568697 9294722 | |
| MESH:D004831 | Epilepsies, Myoclonic | Phenobarbital | 3.50 | 3659116 | |
| MESH:D004828 | Epilepsies, Partial | Phenobarbital | 3.24 | 11558140 3922381 | |
| MESH:D004827 | Epilepsy | Phenobarbital | 2.54 | 20417680 | |
| MESH:D004832 | Epilepsy, Absence | Phenobarbital | 3.01 | 6401628 | |
| MESH:D017029 | Epilepsy, Complex Partial | Phenobarbital | 3.64 | 7750514 | |
| MESH:D004830 | Epilepsy, Tonic-Clonic | Phenobarbital | 3.40 | 3659116 | |
| MESH:D007172 | Erectile Dysfunction | estradiol valerate | 5.22 | 14972507 | |
| MESH:D004938 | Esophageal Neoplasms | Ethanol | 2.57 | 16704527 | |
| MESH:D017889 | Exfoliation Syndrome | Homocysteine | 5.07 | 16504073 | |
| MESH:D005124 | Eye Abnormalities | Tetrachlorodibenzodioxin | 7.23 | 11564622 | |
| MESH:D005124 | Eye Abnormalities | Tretinoin | 7.23 | 16938888 9664655 | |
| MESH:D005218 | Fat Necrosis | Thioacetamide | 5.08 | 16456712 | |
| MESH:D005234 | Fatty Liver | Amiodarone | 18.76 | 14986274 | |
| MESH:D005234 | Fatty Liver | Dietary Fats | 18.76 | 17967931 19551842 19004024 18296743 | |
| MESH:D005234 | Fatty Liver | Ethanol | 18.76 | 19236843 18620774 16409862 | |
| MESH:D005234 | Fatty Liver | Ethinyl Estradiol | 18.76 | 15345470 | |
| MESH:D005234 | Fatty Liver | Raloxifene | 18.76 | 17473493 | |
| MESH:D005235 | Fatty Liver, Alcoholic | Ethanol | 5.03 | 17920746 | |
| MESH:D005310 | Fetal Alcohol Syndrome | Ethanol | 4.67 | 16946407 15513904 15451040 10194807 | |
| MESH:D005313 | Fetal Death | Tetrachlorodibenzodioxin | 2.85 | 11858732 | |
| MESH:D005327 | Fetal Resorption | Vitamin A | 4.73 | 16054864 | |
| MESH:D005354 | Fibrosarcoma | Methylnitrosourea | 4.61 | 11555667 | |
| MESH:D005355 | Fibrosis | Dietary Fats | 11.26 | 18296743 | |
| MESH:D005355 | Fibrosis | Tetrachlorodibenzodioxin | 11.26 | 20067830 | |
| MESH:D005355 | Fibrosis | Tretinoin | 11.26 | 17994277 | |
| MESH:D005393 | Fish Diseases | malachite green | 5.13 | 15900690 16175963 | |
| MESH:D005756 | Gastritis | Ethanol | 4.06 | 15046732 | |
| MESH:D005901 | Glaucoma | Homocysteine | 4.71 | 16504073 | |
| MESH:D005909 | Glioblastoma | Genistein | 5.77 | 16598420 | |
| MESH:D005909 | Glioblastoma | Tretinoin | 5.77 | 17312396 | |
| MESH:D005910 | Glioma | Methylnitrosourea | 3.28 | 9825942 | |
| MESH:D006058 | Gonadal Disorders | Tetrachlorodibenzodioxin | 3.96 | 10696789 | |
| MESH:D006258 | Head and Neck Neoplasms | Tretinoin | 2.74 | 16096774 | |
| MESH:D006317 | Hearing Loss, Noise-Induced | Tretinoin | 4.52 | 16084493 | |
| MESH:D006330 | Heart Defects, Congenital | Homocysteine | 13.06 | 19638421 | |
| MESH:D006330 | Heart Defects, Congenital | Tetrachlorodibenzodioxin | 13.06 | 11294989 10048152 | |
| MESH:D006330 | Heart Defects, Congenital | Tretinoin | 13.06 | 9664655 14991402 | |
| MESH:D006330 | Heart Defects, Congenital | Vitamin A | 13.06 | 10992263 16080930 | |
| MESH:D006331 | Heart Diseases | Raloxifene | 3.09 | 11110106 | |
| MESH:D006333 | Heart Failure | Dobutamine | 4.04 | 17440445 | |
| MESH:D006470 | Hemorrhage | Tetrachlorodibenzodioxin | 2.77 | 11000095 | |
| MESH:D006501 | Hepatic Encephalopathy | Thioacetamide | 4.01 | 18665440 17276928 15929193 | |
| MESH:D006505 | Hepatitis | Caffeine | 12.69 | 11394713 | |
| MESH:D006505 | Hepatitis | Dichlorodiphenyl Dichloroethylene | 12.69 | 16487989 | |
| MESH:D006505 | Hepatitis | Thioacetamide | 12.69 | 16456712 | |
| MESH:D006529 | Hepatomegaly | Amiodarone | 10.98 | 15265979 | |
| MESH:D006529 | Hepatomegaly | Phenobarbital | 10.98 | 16109766 | |
| MESH:D006529 | Hepatomegaly | Tetrachlorodibenzodioxin | 10.98 | 16120746 15340226 12621046 | |
| MESH:D006548 | Hernia, Diaphragmatic | Dexamethasone | 5.43 | 7520565 | |
| MESH:D006548 | Hernia, Diaphragmatic | Vitamin A | 5.43 | 15707848 16490937 16877224 17436238 16863852 16292552 | |
| MESH:D006558 | Herpes Genitalis | Estradiol | 4.39 | 15709030 | |
| MESH:D015658 | HIV Infections | Vitamin A | 3.47 | 16960176 | |
| MESH:D006679 | HIV Seropositivity | Vitamin A | 4.97 | 17209195 | |
| MESH:D019584 | Hot Flashes | Estradiol | 3.12 | 17088409 | |
| MESH:D006869 | Hydronephrosis | Tetrachlorodibenzodioxin | 3.41 | 8697196 16354765 15340226 18606429 16959395 | |
| MESH:D006930 | Hyperalgesia | Ethanol | 6.33 | 18783367 | |
| MESH:D006930 | Hyperalgesia | Tretinoin | 6.33 | 16870215 | |
| MESH:D017588 | Hyperandrogenism | Flutamide | 4.82 | 15356085 | |
| MESH:D006937 | Hypercholesterolemia | Amiodarone | 7.30 | 8137927 9751232 | |
| MESH:D006937 | Hypercholesterolemia | Dietary Fats | 7.30 | 21332399 | |
| MESH:D017681 | Hypereosinophilic Syndrome | Tretinoin | 3.96 | 16778211 | |
| MESH:D020138 | Hyperhomocysteinemia | Homocysteine | 4.17 | 18234410 17292331 17369066 | |
| MESH:D006949 | Hyperlipidemias | Dietary Fats | 3.04 | 21332399 | |
| MESH:D006973 | Hypertension | Dexamethasone | 7.04 | 17042910 | |
| MESH:D006973 | Hypertension | Raloxifene | 7.04 | 17577099 15787275 | |
| MESH:D006973 | Hypertension | Tetrachlorodibenzodioxin | 7.04 | 18850075 18670907 | |
| MESH:D006986 | Hypervitaminosis A | Vitamin A | 5.53 | 16054864 | |
| MESH:D007021 | Hypospadias | Ethinyl Estradiol | 3.20 | 16945680 16569931 | |
| MESH:D007037 | Hypothyroidism | Amiodarone | 3.90 | 17991464 18020914 | |
| MESH:D020244 | Infarction, Middle Cerebral Artery | Progesterone | 3.79 | 15869954 | |
| MESH:D007247 | Infertility, Female | Ethinyl Estradiol | 2.88 | 12013081 | |
| MESH:D007248 | Infertility, Male | Dichlorodiphenyl Dichloroethylene | 12.56 | 12948891 17192596 | |
| MESH:D007248 | Infertility, Male | Ethinyl Estradiol | 12.56 | 17937319 | |
| MESH:D007248 | Infertility, Male | fulvestrant | 12.56 | 11514358 | |
| MESH:D007248 | Infertility, Male | Methylnitrosourea | 12.56 | 7193160 | |
| MESH:D007249 | Inflammation | Dexamethasone | 9.00 | 11099482 8960868 | |
| MESH:D007249 | Inflammation | Dietary Fats | 9.00 | 20412841 | |
| MESH:D007249 | Inflammation | Progesterone | 9.00 | 15869954 | |
| MESH:D007249 | Inflammation | Tetrachlorodibenzodioxin | 9.00 | 12878042 12200463 | |
| MESH:D007299 | Insect Bites and Stings | Permethrin | 5.19 | 15189238 12749493 12971516 | |
| MESH:D007333 | Insulin Resistance | bisphenol A | 9.86 | 16393666 | |
| MESH:D007333 | Insulin Resistance | Dietary Fats | 9.86 | 18457598 11836018 | |
| MESH:D007333 | Insulin Resistance | Estradiol | 9.86 | 16393666 16627594 | |
| MESH:D007410 | Intestinal Diseases | Tretinoin | 3.16 | 17994277 | |
| MESH:D019586 | Intracranial Hypertension | Vitamin A | 5.18 | 15955940 | |
| OMIM:262400 | ISOLATED GROWTH HORMONE DEFICIENCY, TYPE IA | marker/mechanism | |||
| OMIM:612781 | ISOLATED GROWTH HORMONE DEFICIENCY, TYPE IB | marker/mechanism | |||
| OMIM:173100 | ISOLATED GROWTH HORMONE DEFICIENCY, TYPE II | marker/mechanism | |||
| MESH:D007569 | Jaw Abnormalities | Ethanol | 13.93 | 15513904 | |
| MESH:D007569 | Jaw Abnormalities | Tetrachlorodibenzodioxin | 13.93 | 16580747 | |
| MESH:D007569 | Jaw Abnormalities | Tretinoin | 13.93 | 15992940 17551590 | |
| MESH:D017492 | Keratosis, Seborrheic | alitretinoin | 5.01 | 16144296 | |
| MESH:D007674 | Kidney Diseases | Cadmium Chloride | 5.05 | 16962696 | |
| MESH:D007674 | Kidney Diseases | Estradiol | 5.05 | 15618244 | |
| MESH:D007680 | Kidney Neoplasms | Estradiol | 2.48 | 15610895 | |
| MESH:C537505 | Kowarski syndrome | marker/mechanism | |||
| MESH:D007859 | Learning Disorders | Ethanol | 3.61 | 15451040 | |
| MESH:D007889 | Leiomyoma | Raloxifene | 3.92 | 16973256 | |
| MESH:D007938 | Leukemia | Genistein | 8.63 | 17468513 18980019 | |
| MESH:D007938 | Leukemia | Permethrin | 8.63 | 12937054 | |
| MESH:D007938 | Leukemia | Tretinoin | 8.63 | 17143497 | |
| MESH:D015451 | Leukemia, Lymphocytic, Chronic, B-Cell | Disulfiram | 3.88 | 17026967 | |
| MESH:D007951 | Leukemia, Myeloid | Tretinoin | 3.14 | 16482212 19285840 16932348 | |
| MESH:D015470 | Leukemia, Myeloid, Acute | Tretinoin | 1.95 | 16294345 17596541 19850784 | |
| MESH:D015473 | Leukemia, Promyelocytic, Acute | Tretinoin | 2.72 | 16788101 17107899 17649720 16891316 17294898 9834237 16823087 17361223 12679006 19642359 17368321 19035177 16331271 19075265 16140955 17712046 16766008 17339181 16935935 17217047 17506722 17301526 19225113 15748426 19029980 | |
| MESH:D017880 | Limb Deformities, Congenital | Dichlorodiphenyl Dichloroethylene | 25.78 | 12745335 | |
| MESH:D017880 | Limb Deformities, Congenital | Disulfiram | 25.78 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Ethanol | 25.78 | 17676605 | |
| MESH:D017880 | Limb Deformities, Congenital | Methylnitrosourea | 25.78 | 15526292 | |
| MESH:D017880 | Limb Deformities, Congenital | Tretinoin | 25.78 | 9224671 | |
| MESH:D017880 | Limb Deformities, Congenital | Vitamin A | 25.78 | 16054864 | |
| MESH:D008064 | Lipidoses | Amiodarone | 3.05 | 17567588 15342952 | |
| MESH:D008103 | Liver Cirrhosis | Dietary Fats | 12.70 | 18296743 | |
| MESH:D008103 | Liver Cirrhosis | Ethanol | 12.70 | 15289165 | |
| MESH:D008103 | Liver Cirrhosis | Phenobarbital | 12.70 | 21047994 | |
| MESH:D008103 | Liver Cirrhosis | Vitamin A | 12.70 | 16256175 | |
| MESH:D008104 | Liver Cirrhosis, Alcoholic | Ethanol | 4.47 | 18295389 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | therapeutic | 15334695 | ||
| MESH:D008106 | Liver Cirrhosis, Experimental | Dexamethasone | 11.24 | 16718785 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Estradiol | 11.24 | 14716833 14659978 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Ethanol | 11.24 | 18166357 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Genistein | 11.24 | 17823541 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tetrachlorodibenzodioxin | 11.24 | 12878042 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Thioacetamide | 11.24 | 12679928 17127702 16097051 11682029 18416461 18032466 16098781 15158331 11481614 16126171 15334695 15316131 12891558 15078482 12531686 18031379 15288473 17355460 15075984 11172339 18263696 16343077 10677585 15716488 12085344 18395095 18606216 17292413 14739098 15288472 17050028 17629604 15465738 15095483 18615449 18380797 16489207 15474484 16511523 18295389 12175628 12557150 15362042 16248980 18458672 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Tretinoin | 11.24 | 18397230 16248980 | |
| MESH:D008106 | Liver Cirrhosis, Experimental | Vitamin A | 11.24 | 16248980 | |
| MESH:D008107 | Liver Diseases | Phenobarbital | 5.55 | 19363144 | |
| MESH:D008107 | Liver Diseases | Thioacetamide | 5.55 | 18374380 15158337 16337175 | |
| MESH:D008107 | Liver Diseases | Vitamin A | 5.55 | 16175620 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Ethanol | 9.52 | 17347304 17207112 | |
| MESH:D008108 | Liver Diseases, Alcoholic | Vitamin A | 9.52 | 16762690 | |
| MESH:D017114 | Liver Failure, Acute | Thioacetamide | 3.76 | 17276928 15633222 15313186 12479984 | |
| MESH:D008113 | Liver Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 6.00 | 9643874 | |
| MESH:D008113 | Liver Neoplasms | Phenobarbital | 6.00 | 19482888 19812893 15975961 8742319 19073162 21047994 | |
| MESH:D008113 | Liver Neoplasms | Tetrachlorodibenzodioxin | 6.00 | 16984957 | |
| MESH:D008114 | Liver Neoplasms, Experimental | 9,10-Dimethyl-1,2-benzanthracene | 10.82 | 1399818 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Phenobarbital | 10.82 | 17172636 18308698 1399818 2563599 6150874 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Tetrachlorodibenzodioxin | 10.82 | 12151625 | |
| MESH:D008114 | Liver Neoplasms, Experimental | Vitamin A | 10.82 | 17113696 | |
| MESH:D008133 | Long QT Syndrome | Amiodarone | 7.08 | 11989578 15350150 17391786 | |
| MESH:D008133 | Long QT Syndrome | Dobutamine | 7.08 | 19353679 | |
| MESH:D038061 | Lower Extremity Deformities, Congenital | Methylnitrosourea | 4.85 | 16080182 | |
| MESH:D008171 | Lung Diseases | Amiodarone | 10.10 | 12587719 | |
| MESH:D008171 | Lung Diseases | Dobutamine | 10.10 | 16638327 | |
| MESH:D008171 | Lung Diseases | Vitamin A | 10.10 | 16863852 | |
| MESH:D017563 | Lung Diseases, Interstitial | Amiodarone | 3.84 | 18516814 | |
| MESH:D008175 | Lung Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 5.52 | 11376689 | |
| MESH:D008175 | Lung Neoplasms | alitretinoin | 5.52 | 16413115 | |
| MESH:D008175 | Lung Neoplasms | Dexamethasone | 5.52 | 11195469 15824018 | |
| MESH:D008175 | Lung Neoplasms | Methylnitrosourea | 5.52 | 18062963 | |
| MESH:D008175 | Lung Neoplasms | Tetrachlorodibenzodioxin | 5.52 | 19555203 11884234 | |
| MESH:D008223 | Lymphoma | 9,10-Dimethyl-1,2-benzanthracene | 6.89 | 11376689 | |
| MESH:D008223 | Lymphoma | Methylnitrosourea | 6.89 | 11418001 16257854 | |
| MESH:D016393 | Lymphoma, B-Cell | Methylnitrosourea | 4.19 | 14633661 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | marker/mechanism | 17584969 12082019 | ||
| MESH:D008325 | Mammary Neoplasms, Experimental | 9,10-Dimethyl-1,2-benzanthracene | 14.34 | 10697514 1500032 12844480 16082771 11807958 18840765 8985016 16153821 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Estradiol | 14.34 | 16891317 11807958 17203775 11408345 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Genistein | 14.34 | 14578162 12929590 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Methylnitrosourea | 14.34 | 11751437 14633655 10767621 16827153 15313902 12931682 16619500 15688392 15113128 19196723 11807958 10838139 14999141 16051031 17131329 17020996 16944150 | |
| MESH:D008325 | Mammary Neoplasms, Experimental | Progesterone | 14.34 | 17203775 11408345 | |
| MESH:D020149 | Manganese Poisoning | Estradiol | 3.85 | 19453300 | |
| MESH:D008527 | Medulloblastoma | Tretinoin | 2.50 | 17453147 | |
| MESH:D008545 | Melanoma | Disulfiram | 3.37 | 15367699 | |
| MESH:D008545 | Melanoma | Tretinoin | 3.37 | 16752155 | |
| MESH:D008569 | Memory Disorders | Ethanol | 3.60 | 15451040 18411066 | |
| MESH:D008591 | Meningomyelocele | Homocysteine | 10.39 | 16602021 | |
| MESH:D008591 | Meningomyelocele | Tretinoin | 10.39 | 16940565 | |
| MESH:D008708 | Methemoglobinemia | malachite green | 4.90 | 18363129 | |
| MESH:D018200 | Mixed Tumor, Mullerian | Raloxifene | 4.92 | 15863610 | |
| MESH:D009101 | Multiple Myeloma | Dexamethasone | 9.64 | 15744524 16118317 15867202 | |
| MESH:D009101 | Multiple Myeloma | Raloxifene | 9.64 | 16497877 | |
| MESH:D009101 | Multiple Myeloma | Vitamin A | 9.64 | 16374440 | |
| MESH:D009181 | Mycoses | Amiodarone | 4.26 | 17974566 12754197 | |
| MESH:D009190 | Myelodysplastic Syndromes | Dexamethasone | 6.23 | 9809623 | |
| MESH:D009190 | Myelodysplastic Syndromes | Tretinoin | 6.23 | 17596541 | |
| MESH:D009203 | Myocardial Infarction | Genistein | 5.24 | 17141266 | |
| MESH:D009203 | Myocardial Infarction | Homocysteine | 5.24 | 17412321 | |
| MESH:D017202 | Myocardial Ischemia | Dobutamine | 7.71 | 12447174 | |
| MESH:D017202 | Myocardial Ischemia | Tetrachlorodibenzodioxin | 7.71 | 12213967 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Estradiol | 6.88 | 16810080 | |
| MESH:D015428 | Myocardial Reperfusion Injury | Genistein | 6.88 | 17141266 | |
| MESH:D020191 | Myoclonic Epilepsies, Progressive | Phenobarbital | 3.85 | 17484760 | |
| MESH:D009232 | Myxoma | Raloxifene | 4.92 | 16343187 | |
| MESH:D009361 | Neoplasm Invasiveness | Disulfiram | 4.71 | 18047805 | |
| MESH:D009362 | Neoplasm Metastasis | Disulfiram | 3.73 | 15367699 | |
| MESH:D009369 | Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 12.10 | 11544531 | |
| MESH:D009369 | Neoplasms | alitretinoin | 12.10 | 16946489 | |
| MESH:D009369 | Neoplasms | Disulfiram | 12.10 | 17079463 | |
| MESH:D009369 | Neoplasms | Methylnitrosourea | 12.10 | 15533788 | |
| MESH:D009369 | Neoplasms | Tretinoin | 12.10 | 16946489 16594593 | |
| MESH:D009374 | Neoplasms, Experimental | Methylnitrosourea | 3.87 | 12696579 | |
| MESH:D009389 | Neovascularization, Pathologic | Disulfiram | 8.40 | 15367699 | |
| MESH:D009389 | Neovascularization, Pathologic | Estradiol | 8.40 | 17289903 | |
| MESH:D009421 | Nervous System Malformations | bisphenol A | 24.47 | 16427766 11399458 | |
| MESH:D009421 | Nervous System Malformations | Estradiol | 24.47 | 11399458 16427766 | |
| MESH:D009421 | Nervous System Malformations | Genistein | 24.47 | 16427766 | |
| MESH:D009421 | Nervous System Malformations | Tetrachlorodibenzodioxin | 24.47 | 14600291 | |
| MESH:D009421 | Nervous System Malformations | Tretinoin | 24.47 | 9125849 | |
| MESH:D009436 | Neural Tube Defects | Tretinoin | 6.21 | 9142499 | |
| MESH:D009436 | Neural Tube Defects | Vitamin A | 6.21 | 17400914 | |
| MESH:D009442 | Neurilemmoma | Methylnitrosourea | 4.86 | 11555667 | |
| MESH:D020258 | Neurotoxicity Syndromes | Disulfiram | 4.20 | 11005259 | |
| MESH:D009765 | Obesity | Dietary Fats | 2.11 | 17217161 18674790 21332399 19632207 20518802 16723640 20132043 18457598 11836018 | |
| MESH:D010018 | Osteomalacia | Phenobarbital | 3.74 | 17016548 | |
| MESH:D010024 | Osteoporosis | Genistein | 9.72 | 19401787 | |
| MESH:D010024 | Osteoporosis | Levonorgestrel | 9.72 | 12665316 | |
| MESH:D010024 | Osteoporosis | Raloxifene | 9.72 | 19059307 17882678 15775268 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Genistein | 8.22 | 16169203 | |
| MESH:D015663 | Osteoporosis, Postmenopausal | Raloxifene | 8.22 | 17893378 17823083 15758505 15579764 | |
| MESH:D012516 | Osteosarcoma | Disulfiram | 4.67 | 18047805 | |
| MESH:D010049 | Ovarian Diseases | bisphenol A | 4.36 | 11985600 | |
| MESH:D010051 | Ovarian Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 15.68 | 16891317 | |
| MESH:D010051 | Ovarian Neoplasms | Disulfiram | 15.68 | 17026967 | |
| MESH:D010051 | Ovarian Neoplasms | Estradiol | 15.68 | 19401270 | |
| MESH:D010051 | Ovarian Neoplasms | Genistein | 15.68 | 19005980 | |
| MESH:D010051 | Ovarian Neoplasms | Progesterone | 15.68 | 17393432 16525653 | |
| MESH:D010051 | Ovarian Neoplasms | Tretinoin | 15.68 | 16936753 | |
| MESH:D010146 | Pain | Tretinoin | 2.41 | 16870215 | |
| MESH:D010190 | Pancreatic Neoplasms | Ethanol | 10.14 | 12384795 | |
| MESH:D010190 | Pancreatic Neoplasms | Methylnitrosourea | 10.14 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Phenobarbital | 10.14 | 16965848 | |
| MESH:D010190 | Pancreatic Neoplasms | Tretinoin | 10.14 | 15976015 | |
| MESH:D016584 | Panic Disorder | Ethinyl Estradiol | 3.11 | 11578682 | |
| MESH:D010212 | Papilloma | 9,10-Dimethyl-1,2-benzanthracene | 4.68 | 15173996 16517061 17234724 | |
| MESH:D010300 | Parkinson Disease | Homocysteine | 3.31 | 16275827 | |
| MESH:D010382 | Peliosis Hepatis | Tetrachlorodibenzodioxin | 3.61 | 12520081 | |
| MESH:D011085 | Polycystic Ovary Syndrome | Flutamide | 4.44 | 15356085 | |
| MESH:D017499 | Porokeratosis | alitretinoin | 5.36 | 16144296 | |
| MESH:D017119 | Porphyria Cutanea Tarda | Tetrachlorodibenzodioxin | 2.96 | 18163543 | |
| MESH:D011230 | Precancerous Conditions | Phenobarbital | 3.09 | 2563599 | |
| MESH:D054198 | Precursor Cell Lymphoblastic Leukemia-Lymphoma | Dexamethasone | 3.16 | 21297632 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | bisphenol A | 7.44 | 10548101 | |
| MESH:D011297 | Prenatal Exposure Delayed Effects | Tetrachlorodibenzodioxin | 7.44 | 11896295 11399792 11118676 11222880 | |
| MESH:D011470 | Prostatic Hyperplasia | Calcitriol | 4.15 | 15572423 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | bisphenol A | 8.68 | 20887781 | |
| MESH:D019048 | Prostatic Intraepithelial Neoplasia | Estradiol | 8.68 | 20887781 | |
| MESH:D011471 | Prostatic Neoplasms | bisphenol A | 2.24 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Calcitriol | 2.24 | 15754350 16289102 18247401 16644109 12479363 | |
| MESH:D011471 | Prostatic Neoplasms | Disulfiram | 2.24 | 19789329 | |
| MESH:D011471 | Prostatic Neoplasms | Estradiol | 2.24 | 16740699 | |
| MESH:D011471 | Prostatic Neoplasms | Flutamide | 2.24 | 3169114 | |
| MESH:D011471 | Prostatic Neoplasms | Genistein | 2.24 | 15378649 15256057 16925846 | |
| MESH:D011471 | Prostatic Neoplasms | Methylnitrosourea | 2.24 | 12376480 15682402 | |
| MESH:D011471 | Prostatic Neoplasms | Raloxifene | 2.24 | 16536755 15731164 16220300 | |
| MESH:D011507 | Proteinuria | Tretinoin | 3.03 | 16636307 | |
| MESH:D011537 | Pruritus | Ethinyl Estradiol | 7.94 | 15861022 16919318 | |
| MESH:D011537 | Pruritus | Levonorgestrel | 7.94 | 15861022 | |
| MESH:D019310 | Pseudolymphoma | Phenobarbital | 3.86 | 12752131 | |
| MESH:D011625 | Pterygium | Tretinoin | 4.17 | 16723453 | |
| MESH:D011629 | Puberty, Precocious | bisphenol A | 4.16 | 10548101 | |
| MESH:D011658 | Pulmonary Fibrosis | Amiodarone | 2.58 | 12490602 12832656 11597910 | |
| MESH:D011693 | Purpura | Raloxifene | 4.92 | 15770314 | |
| MESH:D012128 | Respiratory Distress Syndrome, Adult | Dexamethasone | 3.44 | 18379247 11700416 | |
| MESH:D012127 | Respiratory Distress Syndrome, Newborn | Vitamin A | 5.18 | 16877224 | |
| MESH:D015619 | Respiratory System Abnormalities | Tetrachlorodibenzodioxin | 3.24 | 18990726 | |
| MESH:D012162 | Retinal Degeneration | Methylnitrosourea | 3.93 | 18172121 18155124 | |
| MESH:D012175 | Retinoblastoma | Methylnitrosourea | 4.86 | 11555667 | |
| MESH:D012208 | Rhabdomyosarcoma | Tretinoin | 3.52 | 16283617 16116481 | |
| MESH:D012468 | Salivary Gland Neoplasms | Progesterone | 2.60 | 18045962 | |
| MESH:D012559 | Schizophrenia | Homocysteine | 3.01 | 16641680 | |
| MESH:D012640 | Seizures | Ethanol | 4.70 | 9754883 | |
| MESH:D012640 | Seizures | Phenobarbital | 4.70 | 3137016 16876388 11442880 4039156 | |
| MESH:D003294 | Seizures, Febrile | Phenobarbital | 4.20 | 6407741 | |
| OMIM:609620 | SHORT QT SYNDROME 1 | Amiodarone | 4.46 | 18724381 | |
| OMIM:604271 | SHORT STATURE, IDIOPATHIC, AUTOSOMAL | marker/mechanism | |||
| MESH:D012871 | Skin Diseases | Vitamin A | 3.16 | 18709164 | |
| MESH:D012878 | Skin Neoplasms | 9,10-Dimethyl-1,2-benzanthracene | 7.69 | 15173996 16517061 11376689 8985016 | |
| MESH:D012878 | Skin Neoplasms | Tetrachlorodibenzodioxin | 7.69 | 16192470 | |
| MESH:D012878 | Skin Neoplasms | Tretinoin | 7.69 | 16467112 | |
| MESH:D012893 | Sleep Disorders | Caffeine | 4.69 | 19395429 | |
| MESH:D007319 | Sleep Initiation and Maintenance Disorders | Caffeine | 4.47 | 17225163 | |
| MESH:D013088 | Spermatocele | Ethinyl Estradiol | 3.31 | 16709447 | |
| MESH:D013119 | Spinal Cord Injuries | Progesterone | 3.66 | 15862959 16503802 | |
| MESH:D013272 | Stomach Diseases | Dexamethasone | 3.70 | 15472012 | |
| MESH:D013274 | Stomach Neoplasms | Ethanol | 3.10 | 18456281 | |
| MESH:D013274 | Stomach Neoplasms | Methylnitrosourea | 3.10 | 15930296 16257854 18593901 | |
| MESH:D013274 | Stomach Neoplasms | Tretinoin | 3.10 | 17261132 | |
| MESH:D013276 | Stomach Ulcer | Amiodarone | 8.96 | 18087811 | |
| MESH:D013276 | Stomach Ulcer | Dexamethasone | 8.96 | 15138204 | |
| MESH:D013276 | Stomach Ulcer | Ethanol | 8.96 | 17189318 16755016 9211565 11906479 9562338 17918041 | |
| MESH:D020521 | Stroke | Raloxifene | 3.32 | 16837676 | |
| MESH:D019966 | Substance-Related Disorders | bisphenol A | 3.36 | 16045194 16684133 | |
| MESH:D013375 | Substance Withdrawal Syndrome | Ethanol | 3.71 | 9754883 | |
| MESH:D013610 | Tachycardia | Amiodarone | 3.70 | 11238279 | |
| MESH:D017180 | Tachycardia, Ventricular | Amiodarone | 3.60 | 19225199 | |
| MESH:D019851 | Thrombophilia | Ethinyl Estradiol | 3.04 | 11994571 | |
| MESH:D013927 | Thrombosis | Ethinyl Estradiol | 2.62 | 15669648 | |
| MESH:D013953 | Thymus Neoplasms | Methylnitrosourea | 4.61 | 11418001 | |
| MESH:D013959 | Thyroid Diseases | Amiodarone | 17.44 | 19731979 | |
| MESH:D013959 | Thyroid Diseases | Tetrachlorodibenzodioxin | 17.44 | 12697716 | |
| MESH:D013959 | Thyroid Diseases | Thyroxine | 17.44 | 19910387 | |
| MESH:D013964 | Thyroid Neoplasms | Methylnitrosourea | 9.28 | 7505956 3078959 | |
| MESH:D013964 | Thyroid Neoplasms | Phenobarbital | 9.28 | 1399818 | |
| MESH:D013964 | Thyroid Neoplasms | Tretinoin | 9.28 | 16026305 17045167 | |
| MESH:D013971 | Thyrotoxicosis | Amiodarone | 4.25 | 18020914 19584973 | |
| MESH:D013978 | Tibial Fractures | Estradiol | 11.59 | 19048282 | |
| MESH:D013978 | Tibial Fractures | Raloxifene | 11.59 | 19048282 | |
| MESH:D014062 | Tongue Neoplasms | Tretinoin | 3.24 | 16051514 | |
| MESH:D016171 | Torsades de Pointes | Amiodarone | 8.70 | 17467628 11989578 | |
| MESH:D016171 | Torsades de Pointes | Dobutamine | 8.70 | 19353679 | |
| MESH:D014376 | Tuberculosis | Tretinoin | 2.81 | 16040207 | |
| MESH:D001749 | Urinary Bladder Neoplasms | Raloxifene | 2.55 | 17572228 | |
| MESH:D014570 | Urologic Diseases | Dichlorodiphenyl Dichloroethylene | 5.10 | 16487989 | |
| MESH:D002583 | Uterine Cervical Neoplasms | Tretinoin | 3.13 | 16129372 | |
| MESH:D014591 | Uterine Diseases | bisphenol A | 4.37 | 14652134 | |
| MESH:D014594 | Uterine Neoplasms | Ethinyl Estradiol | 2.71 | 14692618 | |
| MESH:D014604 | Uveal Neoplasms | Tretinoin | 3.97 | 16752155 | |
| MESH:D014605 | Uveitis | Dexamethasone | 4.18 | 1336536 | |
| MESH:D054079 | Vascular Malformations | Tetrachlorodibenzodioxin | 3.96 | 12125929 | |
| MESH:D054556 | Venous Thromboembolism | Raloxifene | 4.57 | 16837676 | |
| MESH:D020246 | Venous Thrombosis | Ethinyl Estradiol | 8.91 | 15869587 14671159 | |
| MESH:D020246 | Venous Thrombosis | Levonorgestrel | 8.91 | 15869587 | |
| MESH:D014802 | Vitamin A Deficiency | Vitamin A | 4.70 | 16960172 16175781 16146918 | |
| MESH:D014820 | Vitiligo | Tretinoin | 3.46 | 16761959 | |
| MESH:D014846 | Vulvar Neoplasms | Raloxifene | 4.92 | 16343187 | |
| MESH:D019282 | Wasting Syndrome | Tetrachlorodibenzodioxin | 3.61 | 15886252 | |
| MESH:D015430 | Weight Gain | Dietary Fats | 3.20 | 16723640 | |
| MESH:D009396 | Wilms Tumor | Tretinoin | 3.43 | 16287080 |
| Pathway ID | Pathway Name |
|---|---|
| KEGG:04060 | Cytokine-cytokine receptor interaction |
| KEGG:04630 | Jak-STAT signaling pathway |
| KEGG:04080 | Neuroactive ligand-receptor interaction |
Drug Bank