Annotation Detail for COPG2
Basic Information
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| Gene Symbol: | COPG2 ( 2-COP,DKFZp761N09121,FLJ11781 ) |
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| Gene Full Name: | coatomer protein complex, subunit gamma 2 |
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| Band: | 7q32.2 |
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| Quick Links | Entrez ID:26958; OMIM: 604355; Uniprot ID:COPG2_HUMAN; ENSEMBL ID: ; HGNC ID: 2237 |
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| Relate to Another Database: |
SFARIGene;
denovo-db |
| Desease ID | Desease Name |
|---|
| 2124 | Autistic disorder |
| Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
|---|
| D000082 |
Acetaminophen |
Acetaminophen affects the expression of COPG2 mRNA | affects expression | 17562736
|
| D001564 |
Benzo(a)pyrene |
Benzo(a)pyrene results in decreased expression of COPG2 mRNA | decreases expression | 20064835
|
| C009160 |
cyclonite |
cyclonite results in decreased expression of COPG2 mRNA | decreases expression | 19417177
|
| D009532 |
Nickel |
MT1 affects the reaction [Nickel affects the expression of COPG2 mRNA] | affects expression|affects reaction | 16166738
|
| D009532 |
Nickel |
MT2 affects the reaction [Nickel affects the expression of COPG2 mRNA] | affects expression|affects reaction | 16166738
|
| C006253 |
pirinixic acid |
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of COPG2 mRNA | affects binding|decreases expression|increases activity | 19710929
|
| Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
|---|
| MESH:D055371 |
Acute Lung Injury |
|
Nickel |
10.62 | 16166738 |
| MESH:D055371 |
Acute Lung Injury |
|
pirinixic acid |
10.62 | 18653653 |
| MESH:D000230 |
Adenocarcinoma |
|
Benzo(a)pyrene |
2.05 | 20127859 20464547 |
| MESH:D000236 |
Adenoma |
|
Benzo(a)pyrene |
2.84 | 6695378 |
| MESH:D018248 |
Adenoma, Liver Cell |
|
pirinixic acid |
4.02 | 16434500 |
| MESH:D000799 |
Angioedema |
|
Acetaminophen |
4.45 | 10982225 |
| MESH:D017544 |
Aortic Aneurysm, Abdominal |
|
Benzo(a)pyrene |
4.56 | 19183758 |
| MESH:D001321 |
Autistic Disorder |
|
Acetaminophen |
1.40 | 18445737 |
| MESH:D001778 |
Blood Coagulation Disorders |
|
pirinixic acid |
3.52 | 19483382 |
| MESH:D001943 |
Breast Neoplasms |
|
Benzo(a)pyrene |
2.44 | 17474063 20146248 |
| MESH:D001943 |
Breast Neoplasms |
|
Nickel |
2.44 | 15986119 |
| MESH:D006528 |
Carcinoma, Hepatocellular |
|
Acetaminophen |
1.40 | 3084413 |
| MESH:D002294 |
Carcinoma, Squamous Cell |
|
Benzo(a)pyrene |
2.13 | 20419170 |
| MESH:D002386 |
Cataract |
|
Acetaminophen |
2.77 | 10977129 |
| MESH:D002779 |
Cholestasis |
|
pirinixic acid |
3.08 | 19176532 |
| MESH:D017449 |
Dermatitis, Allergic Contact |
|
Nickel |
4.42 | 19470301 17244072 17100760 |
| MESH:D003876 |
Dermatitis, Atopic |
|
pirinixic acid |
2.56 | 18249437 |
| MESH:D003877 |
Dermatitis, Contact |
|
Nickel |
5.04 | 2952479 |
| MESH:D056486 |
Drug-Induced Liver Injury |
|
Acetaminophen |
1.66 | 14986274 15968718 12958197 16081117 12594235 18071297 11834606 11743745 19164858 11287661 16227642 12705907 19923254 11461765 2444490 18713872 17522070 11739529 11421492 19739265 19370779 16109766 17562736 14725611 15619225 17906064 10663392 19085960 16393943 16177239 11529661 19416960 12392966 10915739 12540782 16781746 19420014 10774834 12153990 14550746 16485898 |
| MESH:D056487 |
Drug-Induced Liver Injury, Chronic |
|
Acetaminophen |
4.71 | 19426721 |
| MESH:D004487 |
Edema |
|
pirinixic acid |
2.85 | 12083418 |
| MESH:D004938 |
Esophageal Neoplasms |
|
Benzo(a)pyrene |
2.07 | 16530937 |
| MESH:D005234 |
Fatty Liver |
|
pirinixic acid |
3.14 | 19236843 20131406 |
| MESH:D005756 |
Gastritis |
|
Acetaminophen |
4.29 | 16983495 |
| MESH:D006330 |
Heart Defects, Congenital |
|
Benzo(a)pyrene |
2.82 | 20471113 |
| MESH:D006333 |
Heart Failure |
|
pirinixic acid |
2.73 | 20558911 |
| MESH:D006529 |
Hepatomegaly |
|
pirinixic acid |
3.48 | 19772884 16221962 18467677 19176532 |
| MESH:D015658 |
HIV Infections |
|
Nickel |
3.98 | 17263646 |
| MESH:D006930 |
Hyperalgesia |
|
Acetaminophen |
2.99 | 16870215 |
| MESH:D006943 |
Hyperglycemia |
|
pirinixic acid |
3.53 | 20558911 |
| MESH:D007249 |
Inflammation |
|
Nickel |
3.58 | 16166738 |
| MESH:D007333 |
Insulin Resistance |
|
pirinixic acid |
2.85 | 16306350 |
| MESH:D007674 |
Kidney Diseases |
|
Acetaminophen |
2.38 | 15629191 12587719 |
| MESH:D008106 |
Liver Cirrhosis, Experimental |
|
pirinixic acid |
1.35 | 15474484 |
| MESH:D008107 |
Liver Diseases |
|
Acetaminophen |
1.69 | 16611625 16610002 12969438 12587719 19014921 19784758 19460945 11587558 |
| MESH:D017114 |
Liver Failure, Acute |
|
Acetaminophen |
3.58 | 16871587 17185352 |
| MESH:D008113 |
Liver Neoplasms |
|
Benzo(a)pyrene |
4.73 | 21137059 20195826 |
| MESH:D008113 |
Liver Neoplasms |
|
pirinixic acid |
4.73 | 20007298 16377806 15890375 |
| MESH:D008175 |
Lung Neoplasms |
|
Benzo(a)pyrene |
1.57 | 20464547 18520028 18816296 17053015 18569708 20064080 6695378 20135361 20869020 |
| MESH:D008546 |
Melanoma, Experimental |
|
Acetaminophen |
4.05 | 19513568 |
| MESH:D009062 |
Mouth Neoplasms |
|
Benzo(a)pyrene |
3.46 | 16381670 |
| MESH:D009135 |
Muscular Diseases |
|
pirinixic acid |
3.99 | 16239165 |
| MESH:D009203 |
Myocardial Infarction |
|
pirinixic acid |
2.26 | 19151258 |
| MESH:D015428 |
Myocardial Reperfusion Injury |
|
pirinixic acid |
3.22 | 16411023 |
| MESH:D009369 |
Neoplasms |
|
Benzo(a)pyrene |
5.33 | 11141357 |
| MESH:D009369 |
Neoplasms |
|
pirinixic acid |
5.33 | 17405874 |
| MESH:D019636 |
Neurodegenerative Diseases |
|
Acetaminophen |
3.18 | 18514411 |
| MESH:D009765 |
Obesity |
|
pirinixic acid |
1.88 | 20558911 |
| MESH:D010146 |
Pain |
|
Acetaminophen |
2.69 | 16870215 |
| MESH:D011471 |
Prostatic Neoplasms |
|
Benzo(a)pyrene |
2.91 | 17292933 |
| MESH:D015427 |
Reperfusion Injury |
|
pirinixic acid |
2.53 | 19058328 |
| MESH:D012640 |
Seizures |
|
cyclonite |
4.76 | 19417177 |
| MESH:D012878 |
Skin Neoplasms |
|
Benzo(a)pyrene |
2.51 | 19755658 10029692 |
| MESH:D013274 |
Stomach Neoplasms |
|
Benzo(a)pyrene |
1.56 | 20155912 2093021 |
| MESH:D001749 |
Urinary Bladder Neoplasms |
|
Benzo(a)pyrene |
2.29 | 17053015 |
| MESH:D014581 |
Urticaria |
|
Acetaminophen |
3.38 | 10982225 |
Related Pathway Information