Annotation Detail for AMPD1
Basic Information
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Pathway ID | Pathway Name |
---|
PWY-6353 | purine nucleotides degradation II (aerobic) |
Pathway ID | Pathway Name |
---|
| Metabolism of nucleotides |
Desease ID | Desease Name |
---|
1781 | Rheumatoid arthritis |
1787 | Heart disease |
1878 | Ischemia |
2075 | Heart failure |
2236 | Cardiovascular disease |
Desease Name |
---|
rheumatoid arthritis |
CARDIOVASCULAR |
Coronary Artery Disease |
cardiac function |
PHARMACOGENOMIC |
metabolic syndrome |
METABOLIC |
insulin |
left ventricular dysfunction |
Heart Failure |
congestive heart failure |
Desease Name |
---|
Myoadenylate deaminase deficiency |
Chemical ID |
Chemical Name |
Interaction |
Interaction Action |
Publication |
---|
D000643 |
Ammonium Chloride |
Ammonium Chloride affects the expression of AMPD1 mRNA | affects expression | 16483693
|
D005419 |
Flavonoids |
Flavonoids results in increased expression of AMPD1 mRNA | increases expression | 18035473
|
Disease ID |
Disease Name |
Direct Evidence |
Inference Chemical Name |
Inference Score |
Publication |
---|
MESH:D000138 |
Acidosis |
|
Ammonium Chloride |
4.44 | 18287403 |
MESH:C538234 |
Adenosine monophosphate deaminase deficiency |
marker/mechanism |
|
| |
MESH:D007249 |
Inflammation |
|
Flavonoids |
2.86 | 17296493 |
MESH:D018908 |
Muscle Weakness |
marker/mechanism |
|
| 10996775 |
MESH:D009133 |
Muscular Atrophy |
marker/mechanism |
|
| 10996775 |
Drugbank ID |
Action |
Drug Name |
Description |
---|
DB00131 |
- |
Adenosine monophosphate |
Dietary supplement;Micronutrient |