AutismKB 2.0

Annotation Detail for FOXB1


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Basic Information Top
Gene Symbol:FOXB1 ( FKH5,HFKH-5 )
Gene Full Name: forkhead box B1
Band: 15q22.2
Quick LinksEntrez ID:27023; OMIM: NA; Uniprot ID:FOXB1_HUMAN; ENSEMBL ID: ENSG00000171956; HGNC ID: 3799
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
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Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
D000082 Acetaminophen Acetaminophen affects the expression of FOXB1 mRNAaffects expression 17562736
D009151 Mustard Gas Mustard Gas results in increased expression of FOXB1 mRNAincreases expression 15674844
15674843
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000799 Angioedema Acetaminophen 4.9110982225
MESH:D001249 Asthma Mustard Gas 2.8210378619
MESH:D001321 Autistic Disorder Acetaminophen 1.3918445737
MESH:D001768 Blister Mustard Gas 6.0519167455
MESH:D001989 Bronchiolitis Obliterans Mustard Gas 6.0515286001
MESH:D029481 Bronchitis, Chronic Mustard Gas 6.0517687719 10378619
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 1.413084413
MESH:D002386 Cataract Acetaminophen 2.8310977129
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 1.6817562736 19739265 11739529 16781746 12540782 11461765 19370779 19416960 14550746 14725611 19923254 16081117 12594235 11421492 16485898 19085960 11529661 15968718 18713872 12705907 12392966 16177239 10663392 17906064 2444490 12958197 14986274 17522070 12153990 18071297 19420014 16227642 11743745 11834606 15619225 10915739 16393943 11287661 19164858 16109766 10774834
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 5.1719426721
MESH:D004487 Edema Mustard Gas 3.8511428647 9260866 11428631 11402378
MESH:D004890 Erythema Mustard Gas 6.059357497
MESH:D005756 Gastritis Acetaminophen 4.7416983495
MESH:D006930 Hyperalgesia Acetaminophen 3.1116870215
MESH:D007249 Inflammation Mustard Gas 2.999260866 11428631 8975870 11402378 17524151 9357497 11428647 11428620 16001271
MESH:D007674 Kidney Diseases Acetaminophen 2.4415629191 12587719
MESH:D008107 Liver Diseases Acetaminophen 1.7119014921 16611625 12587719 16610002 19460945 12969438 11587558 19784758
MESH:D017114 Liver Failure, Acute Acetaminophen 3.7416871587 17185352
MESH:D008171 Lung Diseases Mustard Gas 3.7618161513 18702808
MESH:D008175 Lung Neoplasms Mustard Gas 2.183148597 8781369
MESH:D008546 Melanoma, Experimental Acetaminophen 4.3319513568
MESH:D019636 Neurodegenerative Diseases Acetaminophen 3.3118514411
MESH:D009503 Neutropenia Mustard Gas 4.5816761898 7688884
MESH:D010146 Pain Acetaminophen 2.8216870215
MESH:D011041 Poisoning Mustard Gas 4.4015727166
MESH:D011537 Pruritus Mustard Gas 4.9818058305
MESH:D011658 Pulmonary Fibrosis Mustard Gas 3.0710334151 17894541 17720292 17620002 17266442
MESH:D012871 Skin Diseases Mustard Gas 2.8012880345 15451306 16961503
MESH:D014581 Urticaria Acetaminophen 3.5810982225
No data
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Syndromic Genes

Non-syndromic Genes

AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018