AutismKB 2.0

Annotation Detail for STAU2


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Basic Information Top
Gene Symbol:STAU2 ( 39K2,39K3,DKFZp781K0371,MGC119606 )
Gene Full Name: staufen, RNA binding protein, homolog 2 (Drosophila)
Band: 8q21.11
Quick LinksEntrez ID:27067; OMIM: 605920; Uniprot ID:STAU2_HUMAN; ENSEMBL ID: ENSG00000040341; HGNC ID: 11371
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C548651 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester 2-(1'H-indolo-3'-carbonyl)thiazole-4-carboxylic acid methyl ester results in decreased expression of STAU2 mRNAdecreases expression 19933214
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of STAU2 mRNAaffects expression 21346803
D001564 Benzo(a)pyrene Benzo(a)pyrene results in decreased expression of STAU2 mRNAdecreases expression 20064835
20106945
D016572 Cyclosporine Cyclosporine results in decreased expression of STAU2 mRNAdecreases expression 20106945
D008748 Methylcholanthrene Methylcholanthrene results in decreased expression of STAU2 mRNAdecreases expression 20713471
C006253 pirinixic acid pirinixic acid results in increased expression of STAU2 mRNAincreases expression 18301758
D018038 Sodium Selenite Sodium Selenite results in increased expression of STAU2 mRNAincreases expression 18175754
D013749 Tetrachlorodibenzodioxin [Tetrachlorodibenzodioxin co-treated with AHR gene mutant form] results in decreased expression of STAU2 mRNAaffects cotreatment|decreases expression 19465110
C034028 vanadyl sulfate vanadyl sulfate results in decreased expression of STAU2 mRNAdecreases expression 16330358
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 3.1315322242 14514962 11752688
MESH:D055371 Acute Lung Injury pirinixic acid 3.3418653653
MESH:D000230 Adenocarcinoma Benzo(a)pyrene 2.0220464547 20127859
MESH:D000236 Adenoma Benzo(a)pyrene 7.246695378
MESH:D000236 Adenoma Methylcholanthrene 7.2410545420 6695378
MESH:D018248 Adenoma, Liver Cell pirinixic acid 10.8716434500
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 10.8716835633
MESH:D000740 Anemia Tetrachlorodibenzodioxin 3.1411748828
MESH:D017544 Aortic Aneurysm, Abdominal Benzo(a)pyrene 4.3319183758
MESH:D050197 Atherosclerosis Methylcholanthrene 3.5611922910
MESH:D001778 Blood Coagulation Disorders pirinixic acid 9.4619483382
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 9.4612125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 4.1115340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.8915746008
MESH:D001943 Breast Neoplasms Benzo(a)pyrene 1.8817474063 20146248
MESH:D001943 Breast Neoplasms Methylcholanthrene 1.8817474063
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 1.8820435547
MESH:D002277 Carcinoma Methylcholanthrene 8.8910545420
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 8.8916835633
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 1.7816705839
MESH:D002294 Carcinoma, Squamous Cell Benzo(a)pyrene 2.1020419170
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.4716120746 18670907 18850075
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 12.056135515
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 12.0512371664
MESH:D002471 Cell Transformation, Neoplastic Methylcholanthrene 12.0516192471
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.3416835633
MESH:D002779 Cholestasis Cyclosporine 8.2619486331
MESH:D002779 Cholestasis pirinixic acid 8.2619176532
MESH:D019457 Chromosome Breakage Sodium Selenite 5.0115894690
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 2.1816354765 15340226 8697196 12621046 15668235
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 3.2414669216 17141729
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 1.2610048152 15322242 20055451
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.2818551238
MESH:D003876 Dermatitis, Atopic pirinixic acid 2.5118249437
MESH:D003920 Diabetes Mellitus Sodium Selenite 3.9616285004
MESH:D003921 Diabetes Mellitus, Experimental vanadyl sulfate 4.5416684804
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 1.7117107852
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 6.5218551238 21346803
MESH:D056486 Drug-Induced Liver Injury Sodium Selenite 6.5215131321
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 6.5220420201
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 2.9111462148
MESH:D004487 Edema pirinixic acid 7.2312083418
MESH:D004487 Edema Tetrachlorodibenzodioxin 7.2312711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 4.2218230668 15322242 16714409
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 3.2110568697 9294722
MESH:D004938 Esophageal Neoplasms Benzo(a)pyrene 2.0516530937
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 3.1611564622
MESH:D005234 Fatty Liver Cyclosporine 8.2519224547
MESH:D005234 Fatty Liver pirinixic acid 8.2519236843 20131406
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.7111858732
MESH:D005354 Fibrosarcoma Methylcholanthrene 5.2214633661 10962813
MESH:D005355 Fibrosis Cyclosporine 9.3612639820 12168785
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 9.3620067830
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.508708960
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.9110696789
MESH:D006330 Heart Defects, Congenital Benzo(a)pyrene 6.7720471113
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.7711294989 10048152
MESH:D006333 Heart Failure pirinixic acid 2.6520558911
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.7115720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.5411000095
MESH:D006529 Hepatomegaly pirinixic acid 9.1418467677 16221962 19176532 19772884
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 9.1415340226 16120746 12621046
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 4.368697196 16959395 18606429 16354765 15340226
MESH:D006943 Hyperglycemia pirinixic acid 3.3820558911
MESH:D006973 Hypertension Cyclosporine 5.1710903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 5.1718850075 18670907
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.9512878042 12200463
MESH:D007333 Insulin Resistance pirinixic acid 7.7416306350
MESH:D007333 Insulin Resistance Sodium Selenite 7.7414714311
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.5416580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.7615604871
MESH:D007674 Kidney Diseases Cyclosporine 2.448314463 18776723 10903974
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 7.8516705839
MESH:D007680 Kidney Neoplasms Cyclosporine 7.8512371664
MESH:D008106 Liver Cirrhosis, Experimental pirinixic acid 2.1915474484
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 2.1912878042
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 11.237678174
MESH:D008113 Liver Neoplasms Benzo(a)pyrene 11.2320195826 21137059
MESH:D008113 Liver Neoplasms pirinixic acid 11.2315890375 16377806 20007298
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 11.2316984957
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 10.592876784 2876786 6135515
MESH:D008114 Liver Neoplasms, Experimental Methylcholanthrene 10.591399818 598648
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 10.5912151625
MESH:D008175 Lung Neoplasms Benzo(a)pyrene 3.5420464547 6695378 18816296 18569708 20135361 20869020 18520028 17053015 20064080
MESH:D008175 Lung Neoplasms Methylcholanthrene 3.541399818 11893704 7750092 9230183 20970405 10545420 16271038 15390079 21163286 16337739 20512841 6695378 17909032
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 3.5411884234 19555203
MESH:D016393 Lymphoma, B-Cell Sodium Selenite 4.2814737004
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 5.1116801185
MESH:D009062 Mouth Neoplasms Benzo(a)pyrene 3.3516381670
MESH:D009135 Muscular Diseases pirinixic acid 3.7616239165
MESH:D009203 Myocardial Infarction pirinixic acid 2.2119151258
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 3.1812213967
MESH:D015428 Myocardial Reperfusion Injury pirinixic acid 3.1016411023
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.1518551238 7678174
MESH:D009369 Neoplasms Benzo(a)pyrene 5.1311141357
MESH:D009369 Neoplasms pirinixic acid 5.1317405874
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.7617954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.4719348381 18481113
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 3.4514600291
MESH:D009765 Obesity pirinixic acid 1.8520558911
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.6216049721
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.5712520081
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.8018163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.4012371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.4811118676 11222880 11896295 11399792
MESH:D011471 Prostatic Neoplasms Benzo(a)pyrene 3.1717292933
MESH:D011471 Prostatic Neoplasms Sodium Selenite 3.1718760546
MESH:D011565 Psoriasis Cyclosporine 2.2916882103
MESH:D015427 Reperfusion Injury pirinixic acid 2.4719058328
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 4.0818990726
MESH:D012640 Seizures 2,6-dinitrotoluene 2.6718551238
MESH:D012878 Skin Neoplasms Benzo(a)pyrene 5.7619755658 10029692
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.7616192470
MESH:D013274 Stomach Neoplasms Benzo(a)pyrene 1.562093021 20155912
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 4.2212697716
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 5.2116049721
MESH:D001749 Urinary Bladder Neoplasms Benzo(a)pyrene 5.2117053015
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.6010091137
MESH:D014605 Uveitis Cyclosporine 4.301336536
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.9112125929
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.5715886252
MESH:D014985 Xerophthalmia Cyclosporine 4.7617120751
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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