AutismKB 2.0

Annotation Detail for CIDEB


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Basic Information Top
Gene Symbol:CIDEB ( - )
Gene Full Name: cell death-inducing DFFA-like effector b
Band: 14q12
Quick LinksEntrez ID:27141; OMIM: 604441; Uniprot ID:CIDEB_HUMAN; ENSEMBL ID: ENSG00000136305; HGNC ID: 1977
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C063002 2,3-dimethoxy-1,4-naphthoquinone 2,3-dimethoxy-1,4-naphthoquinone results in decreased expression of CIDEB mRNAdecreases expression 17547211
C013813 4-anisidine 4-anisidine results in decreased expression of CIDEB mRNAdecreases expression 12929121
D000082 Acetaminophen Acetaminophen affects the expression of CIDEB mRNAaffects expression 17562736
D016604 Aflatoxin B1 Aflatoxin B1 affects the expression of CIDEB proteinaffects expression 20106945
D001151 Arsenic [Arsenic co-treated with Fluorides] results in decreased expression of CIDEB mRNAaffects cotreatment|decreases expression 19962721
D001151 Arsenic Arsenic results in decreased expression of CIDEB mRNAdecreases expression 19962721
C006632 arsenic trioxide arsenic trioxide results in decreased expression of CIDEB mRNAdecreases expression 17547211
C006632 arsenic trioxide arsenic trioxide results in increased expression of CIDEB mRNAincreases expression 17530438
D002104 Cadmium Cadmium results in decreased expression of CIDEB mRNAdecreases expression 17547211
D019256 Cadmium Chloride Cadmium Chloride results in decreased expression of CIDEB mRNAdecreases expression 17547211
D020111 Chlorodiphenyl (54% Chlorine) Chlorodiphenyl (54% Chlorine) results in decreased expression of CIDEB mRNAdecreases expression 16934159
D003042 Cocaine Cocaine affects the expression of CIDEB mRNAaffects expression 15681117
D016572 Cyclosporine Cyclosporine results in decreased expression of CIDEB mRNAdecreases expression 20106945
D002945 Cisplatin Cisplatin results in increased expression of CIDEB proteinincreases expression 16803524
D004128 Dimethylnitrosamine Dimethylnitrosamine results in decreased expression of CIDEB mRNAdecreases expression 17547211
D004958 Estradiol Estradiol results in decreased expression of CIDEB mRNAdecreases expression 20106945
D005459 Fluorides [Arsenic co-treated with Fluorides] results in decreased expression of CIDEB mRNAaffects cotreatment|decreases expression 19962721
D005459 Fluorides Fluorides results in decreased expression of CIDEB mRNAdecreases expression 19962721
D005472 Fluorouracil Fluorouracil results in increased expression of CIDEB proteinincreases expression 15585135
16803524
D005492 Folic Acid Folic Acid affects the expression of CIDEB mRNAaffects expression 16361273
D005665 Furosemide Furosemide affects the expression of CIDEB mRNAaffects expression 17497460
D006918 Hydroxyurea Hydroxyurea results in decreased expression of CIDEB mRNAdecreases expression 12929121
D008628 Mercury Mercury results in decreased expression of CIDEB mRNAdecreases expression 17547211
D017239 Paclitaxel Paclitaxel results in decreased expression of CIDEB mRNAdecreases expression 12929121
C031280 pyrazole pyrazole results in decreased expression of CIDEB mRNAdecreases expression 17945193
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CIDEB mRNAincreases expression 20106945
D013749 Tetrachlorodibenzodioxin Tetrachlorodibenzodioxin results in increased expression of CIDEB mRNAincreases expression 15310856
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000014 Abnormalities, Drug-Induced Tetrachlorodibenzodioxin 2.7011752688 14514962 15322242
MESH:D058186 Acute Kidney Injury Cisplatin 8.6015814532 17670903 12690470
MESH:D058186 Acute Kidney Injury Folic Acid 8.6016316344 16595132 17003819
MESH:D000230 Adenocarcinoma arsenic trioxide 13.1619825857 11798837
MESH:D000230 Adenocarcinoma Cisplatin 13.1611798837 17638652
MESH:D000230 Adenocarcinoma Dimethylnitrosamine 13.1616033868
MESH:D000230 Adenocarcinoma Estradiol 13.1611473722
MESH:D000230 Adenocarcinoma Fluorouracil 13.1617638652
MESH:D000236 Adenoma Dimethylnitrosamine 7.0219555203
MESH:D000236 Adenoma Folic Acid 7.0216963246
MESH:D018248 Adenoma, Liver Cell Tetrachlorodibenzodioxin 3.2316835633
MESH:D018246 Adrenocortical Adenoma Arsenic 5.0617306315
MESH:D000544 Alzheimer Disease Folic Acid 3.0117116317
MESH:D000740 Anemia Fluorouracil 8.2416511603 17963324 15504547
MESH:D000740 Anemia Tetrachlorodibenzodioxin 8.2411748828
MESH:D000799 Angioedema Acetaminophen 3.6910982225
MESH:D020261 Arsenic Poisoning Arsenic 2.8318414634 16835338 16251483 12569548
MESH:D050197 Atherosclerosis Arsenic 6.7312928151 19371607
MESH:D050197 Atherosclerosis Cadmium 6.7315687053
MESH:D001321 Autistic Disorder Acetaminophen 2.2918445737
MESH:D001321 Autistic Disorder Folic Acid 2.2921388746
MESH:D001321 Autistic Disorder Mercury 2.2917497416
MESH:D001327 Autoimmune Diseases Mercury 4.7216634805
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 8.5016206674
MESH:D001778 Blood Coagulation Disorders Tetrachlorodibenzodioxin 8.5012125929
MESH:D001836 Body Weight Changes Tetrachlorodibenzodioxin 3.6415340226
MESH:D001848 Bone Diseases, Developmental Tetrachlorodibenzodioxin 2.6715746008
MESH:D019046 Bone Marrow Neoplasms Cisplatin 4.7314601052
MESH:D001859 Bone Neoplasms Paclitaxel 4.4215867366
MESH:D001943 Breast Neoplasms Cisplatin 2.9018382427 19526202
MESH:D001943 Breast Neoplasms Estradiol 2.9014630087 12948864 18497071 17289903 17018787 19861407 16675129 17261762
MESH:D001943 Breast Neoplasms Fluorouracil 2.9018608205 18357371 15136595 16110121 16557594 19217205 16595493
MESH:D001943 Breast Neoplasms Folic Acid 2.9016777985
MESH:D001943 Breast Neoplasms Paclitaxel 2.9018223236 15136595 18234424 16273361 16115903 16244791 11325840 18323546
MESH:D001943 Breast Neoplasms Tetrachlorodibenzodioxin 2.9020435547
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.1911589617
MESH:D002181 Candidiasis, Vulvovaginal Estradiol 4.3116111702
MESH:D002276 Carcinoid Tumor Fluorouracil 4.5216051944
MESH:D002277 Carcinoma Dimethylnitrosamine 13.3019555203
MESH:D002277 Carcinoma Fluorouracil 13.3017121937
MESH:D002277 Carcinoma Tetrachlorodibenzodioxin 13.3016835633
MESH:D002280 Carcinoma, Basal Cell Arsenic 3.5117687452 15504454
MESH:D006528 Carcinoma, Hepatocellular Acetaminophen 16.513084413
MESH:D006528 Carcinoma, Hepatocellular Aflatoxin B1 16.5121507988 12619106 12907637
MESH:D006528 Carcinoma, Hepatocellular Arsenic 16.5117306315 16507464
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 16.5115073043 14691202 11135700 16217749 15553829
MESH:D006528 Carcinoma, Hepatocellular Cisplatin 16.5117982673
MESH:D006528 Carcinoma, Hepatocellular Estradiol 16.5116924424
MESH:D006528 Carcinoma, Hepatocellular Fluorouracil 16.5116799960 17971768 17045692 18930000 16332177 17088986
MESH:D006528 Carcinoma, Hepatocellular Paclitaxel 16.5116313753
MESH:D002289 Carcinoma, Non-Small-Cell Lung Cisplatin 2.9812023789 16685392
MESH:D002291 Carcinoma, Papillary arsenic trioxide 4.7219014326
MESH:D002292 Carcinoma, Renal Cell Fluorouracil 2.9518695887
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 3.9812490120
MESH:D002294 Carcinoma, Squamous Cell Arsenic 10.5118922899 15504454 17687452
MESH:D002294 Carcinoma, Squamous Cell Cisplatin 10.516189445 17066447 18337622
MESH:D002294 Carcinoma, Squamous Cell Dimethylnitrosamine 10.5116033868
MESH:D002294 Carcinoma, Squamous Cell Fluorouracil 10.5117066447 18986760 16757204 16280240
MESH:D002295 Carcinoma, Transitional Cell Arsenic 3.9418640142
MESH:D006332 Cardiomegaly Tetrachlorodibenzodioxin 2.2818670907 16120746 18850075
MESH:D002311 Cardiomyopathy, Dilated Mercury 3.4010334427
MESH:D002318 Cardiovascular Diseases Arsenic 7.3917938729 15738583 19152805
MESH:D002318 Cardiovascular Diseases Folic Acid 7.3916755160
MESH:D002340 Carotid Artery Diseases Arsenic 4.1818022660 16973168
MESH:D002386 Cataract Acetaminophen 2.4910977129
MESH:D002471 Cell Transformation, Neoplastic Cadmium 10.6617332340
MESH:D002471 Cell Transformation, Neoplastic Cyclosporine 10.6612371664
MESH:D002471 Cell Transformation, Neoplastic Estradiol 10.6618566989
MESH:D018281 Cholangiocarcinoma Tetrachlorodibenzodioxin 3.0316835633
MESH:D002779 Cholestasis Cyclosporine 2.8019486331
MESH:D002971 Cleft Lip Folic Acid 3.9021254359
MESH:D002972 Cleft Palate Folic Acid 5.898946559 21254359
MESH:D002972 Cleft Palate Tetrachlorodibenzodioxin 5.8915340226 16354765 8697196 15668235 12621046
MESH:D019970 Cocaine-Related Disorders Cocaine 5.5619606084
MESH:D003110 Colonic Neoplasms Fluorouracil 2.2117018589 16340194 18772588 17725105 17016597 15001691 17169374 16510598 17287894 17172411
MESH:D015179 Colorectal Neoplasms arsenic trioxide 6.3420501625
MESH:D015179 Colorectal Neoplasms Cisplatin 6.3415273666
MESH:D015179 Colorectal Neoplasms Fluorouracil 6.3415148649 16282729 14970324 20501625 16331619 16303861 17016601 18509181 16391804 17401013 17255274 17454858 17094418 16524972 18288408 18383874 18448328 17695437 15289873 18802399 17594712 18949393
MESH:D015179 Colorectal Neoplasms Folic Acid 6.3416963246 16985020 17087956 17245555 17116713
MESH:D015179 Colorectal Neoplasms Paclitaxel 6.3418802399
MESH:D000013 Congenital Abnormalities Tetrachlorodibenzodioxin 2.9314669216 17141729
MESH:D023903 Coronary Restenosis arsenic trioxide 4.0412609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 2.4210525206
MESH:D019465 Craniofacial Abnormalities Tetrachlorodibenzodioxin 2.4220055451 10048152 15322242
MESH:D007644 Darier Disease Fluorouracil 4.6416733453
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 3.9515213294
MESH:D017449 Dermatitis, Allergic Contact Mercury 3.6516823706
MESH:D003924 Diabetes Mellitus, Type 2 Folic Acid 4.4416886840
MESH:D003924 Diabetes Mellitus, Type 2 Tetrachlorodibenzodioxin 4.4417107852
MESH:D003928 Diabetic Nephropathies Estradiol 3.2819279558
MESH:D056486 Drug-Induced Liver Injury Acetaminophen 11.5618713872 11743745 11529661 14725611 16393943 12540782 12392966 11461765 16485898 11739529 17562736 19416960 19370779 12705907 10663392 18071297 10774834 14550746 12153990 16781746 19420014 16177239 15619225 12958197 11834606 12594235 14986274 17522070 2444490 19923254 16227642 16081117 19085960 11287661 17906064 19739265 16109766 10915739 15968718 19164858 11421492
MESH:D056486 Drug-Induced Liver Injury Chlorodiphenyl (54% Chlorine) 11.5617851650
MESH:D056486 Drug-Induced Liver Injury Dimethylnitrosamine 11.568172417
MESH:D056486 Drug-Induced Liver Injury pyrazole 11.5612499123
MESH:D056486 Drug-Induced Liver Injury Tetrachlorodibenzodioxin 11.5620420201
MESH:D056487 Drug-Induced Liver Injury, Chronic Acetaminophen 3.9519426721
MESH:D004362 Drug Toxicity Cisplatin 7.8112649298 12231392 15033597 19839026
MESH:D004362 Drug Toxicity Tetrachlorodibenzodioxin 7.8111462148
MESH:D004417 Dyspnea Furosemide 4.7916935035
MESH:D004487 Edema Furosemide 6.6411834646
MESH:D004487 Edema Tetrachlorodibenzodioxin 6.6412711302 11000095
MESH:D004489 Edema, Cardiac Tetrachlorodibenzodioxin 3.7515322242 18230668 16714409
MESH:D016889 Endometrial Neoplasms Estradiol 7.4219148513 18566989 11473722
MESH:D016889 Endometrial Neoplasms Folic Acid 7.4217301261
MESH:D004715 Endometriosis Tetrachlorodibenzodioxin 2.899294722 10568697
MESH:D004938 Esophageal Neoplasms arsenic trioxide 13.4412903497
MESH:D004938 Esophageal Neoplasms Cisplatin 13.4416481741 15464296 15173087 17638652 16785472
MESH:D004938 Esophageal Neoplasms Dimethylnitrosamine 13.4417016578
MESH:D004938 Esophageal Neoplasms Fluorouracil 13.4416481741 16337965 16785472 15173087 17638652
MESH:D004938 Esophageal Neoplasms Paclitaxel 13.4416481741
MESH:D017889 Exfoliation Syndrome Folic Acid 5.3416504073
MESH:D005124 Eye Abnormalities Tetrachlorodibenzodioxin 2.9011564622
MESH:D005234 Fatty Liver arsenic trioxide 7.2915073043
MESH:D005234 Fatty Liver Cyclosporine 7.2919224547
MESH:D005313 Fetal Death Tetrachlorodibenzodioxin 3.3111858732
MESH:D005355 Fibrosis Cyclosporine 7.9812168785 12639820
MESH:D005355 Fibrosis Tetrachlorodibenzodioxin 7.9820067830
MESH:D005534 Foot Diseases Arsenic 5.416392382
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.1116904648
MESH:D005756 Gastritis Acetaminophen 10.7716983495
MESH:D005756 Gastritis Folic Acid 10.7717171786
MESH:D005885 Gingival Hyperplasia Cyclosporine 4.078708960
MESH:D005901 Glaucoma Folic Acid 4.9316504073
MESH:D005910 Glioma Fluorouracil 2.8116145905
MESH:D006058 Gonadal Disorders Tetrachlorodibenzodioxin 4.4410696789
MESH:D006258 Head and Neck Neoplasms Cisplatin 7.6515102660 15464296
MESH:D006258 Head and Neck Neoplasms Fluorouracil 7.6518337622 15102660 15162350
MESH:D034381 Hearing Loss Cisplatin 9.8419898482
MESH:D034381 Hearing Loss Furosemide 9.8417868369
MESH:D006319 Hearing Loss, Sensorineural Cisplatin 4.2915464296
MESH:D006330 Heart Defects, Congenital Folic Acid 6.6017286298 16524890
MESH:D006330 Heart Defects, Congenital Tetrachlorodibenzodioxin 6.6011294989 10048152
MESH:D006333 Heart Failure Furosemide 3.9716011733 16845234 12660669
MESH:D006457 Hemoglobinuria, Paroxysmal Cyclosporine 4.2715720958
MESH:D006470 Hemorrhage Tetrachlorodibenzodioxin 3.2011000095
MESH:D006529 Hepatomegaly Tetrachlorodibenzodioxin 2.7412621046 15340226 16120746
MESH:D006558 Herpes Genitalis Estradiol 4.8815709030
MESH:D006679 HIV Seropositivity Folic Acid 5.3417209195
MESH:D006689 Hodgkin Disease Cisplatin 3.4716200630 16170182
MESH:D019584 Hot Flashes Estradiol 3.6017088409
MESH:D006869 Hydronephrosis Tetrachlorodibenzodioxin 3.8915340226 16959395 8697196 16354765 18606429
MESH:D006930 Hyperalgesia Acetaminophen 2.5816870215
MESH:D006934 Hypercalcemia Furosemide 4.9317652376
MESH:D053565 Hypercalciuria Furosemide 5.5017652376
MESH:D020138 Hyperhomocysteinemia Folic Acid 4.3716865747 16395265 16397167 16433478 16755160
MESH:D017488 Hyperkeratosis, Epidermolytic Arsenic 4.3217050553
MESH:D006962 Hyperparathyroidism, Secondary Furosemide 5.7215086907
MESH:D006973 Hypertension Arsenic 8.2511953799 9931084 16076760
MESH:D006973 Hypertension Cyclosporine 8.2510903974
MESH:D006973 Hypertension Tetrachlorodibenzodioxin 8.2518850075 18670907
MESH:D046110 Hypertension, Pregnancy-Induced Furosemide 5.1316612254
MESH:D006987 Hypesthesia Arsenic 5.4116093927
MESH:C537153 Hypomagnesemia primary Furosemide 5.5011041285
MESH:D007019 Hypoproteinemia Furosemide 5.7216096441
MESH:D007022 Hypotension Furosemide 4.4711041285
MESH:D007024 Hypotension, Orthostatic Furosemide 5.2715811171
MESH:D007249 Inflammation Tetrachlorodibenzodioxin 1.7812878042 12200463
MESH:D007333 Insulin Resistance Estradiol 2.8716627594 16393666
MESH:D007569 Jaw Abnormalities Tetrachlorodibenzodioxin 3.2016580747
MESH:D007638 Keratoconjunctivitis Sicca Cyclosporine 4.2915604871
MESH:D007642 Keratosis Arsenic 4.8412749816 16930632
MESH:D007673 Kidney Cortex Necrosis Cisplatin 4.9915464296
MESH:D007674 Kidney Diseases Acetaminophen 32.5015629191 12587719
MESH:D007674 Kidney Diseases Cadmium 32.5016322080 16226777 16962696
MESH:D007674 Kidney Diseases Cadmium Chloride 32.5016962696
MESH:D007674 Kidney Diseases Cisplatin 32.5012231392 18289764 12649298 15190930 19839026
MESH:D007674 Kidney Diseases Cyclosporine 32.508314463 10903974 18776723
MESH:D007674 Kidney Diseases Estradiol 32.5015618244
MESH:D007674 Kidney Diseases Furosemide 32.5011041285
MESH:D007674 Kidney Diseases Mercury 32.5017934191
MESH:D007680 Kidney Neoplasms Cyclosporine 11.6912371664
MESH:D007680 Kidney Neoplasms Estradiol 11.6915610895
MESH:D007680 Kidney Neoplasms Fluorouracil 11.6916985049
MESH:D007683 Kidney Tubular Necrosis, Acute Cisplatin 4.6411231351
MESH:D007938 Leukemia arsenic trioxide 2.7615070760
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 3.6612560223 17077332
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.1516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.3214633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 9.4919077051
MESH:D007951 Leukemia, Myeloid Hydroxyurea 9.4916532439
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 2.1119850784 20471514 16968895 17050201 16467208
MESH:D015473 Leukemia, Promyelocytic, Acute Arsenic 7.4517339181
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 7.4515622746 12018890 16330433 16891316 17217047 17712046 15336539 15213294 11161223 11468182 16331271 16823087 15748426 19642359 19225113 19035177 16966277 12712474 17869043 16112521 19075265 17649720 12679006 9834237 17107899
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.2016882451
MESH:D008080 Liposarcoma Paclitaxel 4.6817353645
MESH:D008106 Liver Cirrhosis, Experimental Dimethylnitrosamine 3.4315744066 18237412 14726149 17348192 17724770 18364076 18371158 14659978 17534399 15339415 15369754 14709902 12918455 12925901 15793283 15864749 15383259 17881167 18567088 15942678 15161499 17666798 16570917 16042886 14643895 16270385 18629640 15492853 15733078 17036385 17640959 15067225 15504291 17432682 15723089 15763062 15571005 15138612 15591649 15081153 17201889 15298665 18637143 18672772 15842777 18095165 16603200 16544323 16009107 17196135 15086199 18210741 17203207 17198567 15366600 17719030 14568256 15577212 15798949 15479170 17465448 16169303 18239293 15099470 16627068
MESH:D008106 Liver Cirrhosis, Experimental Estradiol 3.4314659978 14716833
MESH:D008106 Liver Cirrhosis, Experimental Tetrachlorodibenzodioxin 3.4312878042
MESH:D008107 Liver Diseases Acetaminophen 6.4319460945 19784758 19014921 16611625 12587719 12969438 11587558 16610002
MESH:D008107 Liver Diseases Arsenic 6.4311134558
MESH:D008107 Liver Diseases Folic Acid 6.4316877991
MESH:D017114 Liver Failure, Acute Acetaminophen 9.2316871587 17185352
MESH:D017114 Liver Failure, Acute Dimethylnitrosamine 9.2317457977
MESH:D008113 Liver Neoplasms Aflatoxin B1 17.252125692 18177683 9163691 15890375
MESH:D008113 Liver Neoplasms Arsenic 17.2516368122
MESH:D008113 Liver Neoplasms arsenic trioxide 17.2514682389
MESH:D008113 Liver Neoplasms Dimethylnitrosamine 17.2515890375 3113478
MESH:D008113 Liver Neoplasms Fluorouracil 17.2518383874 15113037 16603448 17045692
MESH:D008113 Liver Neoplasms Tetrachlorodibenzodioxin 17.2516984957
MESH:D008114 Liver Neoplasms, Experimental Aflatoxin B1 13.388603461
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 13.3820377131
MESH:D008114 Liver Neoplasms, Experimental Dimethylnitrosamine 13.386150874 1848544 15603536
MESH:D008114 Liver Neoplasms, Experimental Tetrachlorodibenzodioxin 13.3812151625
MESH:D008133 Long QT Syndrome arsenic trioxide 3.2315213294
MESH:D008175 Lung Neoplasms Aflatoxin B1 10.4214755239
MESH:D008175 Lung Neoplasms Arsenic 10.4217976673 17306315 19168569
MESH:D008175 Lung Neoplasms arsenic trioxide 10.4211798837 19825857
MESH:D008175 Lung Neoplasms Cisplatin 10.4211798837 17225452 6189445
MESH:D008175 Lung Neoplasms Dimethylnitrosamine 10.4216061637 19555203 11884234
MESH:D008175 Lung Neoplasms Fluorouracil 10.4215246190
MESH:D008175 Lung Neoplasms Tetrachlorodibenzodioxin 10.4211884234 19555203
MESH:D008178 Lupus Erythematosus, Cutaneous Fluorouracil 4.6415086387
MESH:D008180 Lupus Erythematosus, Systemic Folic Acid 3.3017718048
MESH:D008228 Lymphoma, Non-Hodgkin Paclitaxel 3.9714749477
MESH:D008325 Mammary Neoplasms, Experimental Estradiol 2.4717203775 11807958 11408345 16891317
MESH:D020149 Manganese Poisoning Estradiol 4.3319453300
MESH:D019767 Maxillofacial Abnormalities Folic Acid 5.5416832597
MESH:D008545 Melanoma Cisplatin 3.6515577323 18332650 12393984 12883367 16809738 11135225 16248763 12374674 17761969 18176117 17023156 16432458 18505091
MESH:D008545 Melanoma Paclitaxel 3.6512025231 12040289 16342250
MESH:D018328 Melanoma, Amelanotic Cisplatin 4.6215990972
MESH:D008546 Melanoma, Experimental Acetaminophen 3.4219513568
MESH:D008654 Mesothelioma Cisplatin 3.1917638057
MESH:D008664 Metal Metabolism, Inborn Errors Cyclosporine 4.6416801185
MESH:D009062 Mouth Neoplasms Fluorouracil 3.5118986760 16757204
MESH:D009101 Multiple Myeloma arsenic trioxide 7.1414977855 19549372 11468182 19417148 15949261
MESH:D009101 Multiple Myeloma Paclitaxel 7.1414749477
MESH:D009182 Mycosis Fungoides arsenic trioxide 4.5218349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 3.0616882451 16105982
MESH:D009203 Myocardial Infarction Cocaine 3.9218072171
MESH:D017202 Myocardial Ischemia Arsenic 8.6015371236
MESH:D017202 Myocardial Ischemia Tetrachlorodibenzodioxin 8.6012213967
MESH:D015428 Myocardial Reperfusion Injury Estradiol 3.1616810080
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 3.8116624393
MESH:D009362 Neoplasm Metastasis Paclitaxel 3.1915867366
MESH:D009369 Neoplasms Cisplatin 5.1016773208
MESH:D009369 Neoplasms Fluorouracil 5.1018239605 18600527 16928823
MESH:D009389 Neovascularization, Pathologic Estradiol 3.5817289903
MESH:D009395 Nephritis, Interstitial Cisplatin 4.3415464296
MESH:D009397 Nephrocalcinosis Furosemide 5.7215086907
MESH:D009402 Nephrosis, Lipoid Cyclosporine 4.2917954296
MESH:D009404 Nephrotic Syndrome Cyclosporine 3.1519348381 18481113
MESH:D009421 Nervous System Malformations Estradiol 8.9716427766 11399458
MESH:D009421 Nervous System Malformations Tetrachlorodibenzodioxin 8.9714600291
MESH:D009436 Neural Tube Defects Arsenic 11.7516620997
MESH:D009436 Neural Tube Defects arsenic trioxide 11.7510525206
MESH:D009436 Neural Tube Defects Folic Acid 11.7517438019
MESH:D009447 Neuroblastoma Cisplatin 3.378761367
MESH:D019636 Neurodegenerative Diseases Acetaminophen 2.7518514411
MESH:D017599 Neuroectodermal Tumors Cisplatin 4.558761367
MESH:D020078 Neurogenic Inflammation Arsenic 4.2317056641
MESH:D020258 Neurotoxicity Syndromes Fluorouracil 3.3416436463
MESH:D009503 Neutropenia Folic Acid 4.3616322990
MESH:D053206 Nocturnal Enuresis Furosemide 5.7217945291
MESH:D010014 Osteolysis Paclitaxel 4.8315867366
MESH:D010051 Ovarian Neoplasms Arsenic 14.4917306315
MESH:D010051 Ovarian Neoplasms arsenic trioxide 14.4916624393 19769630 12452020
MESH:D010051 Ovarian Neoplasms Cisplatin 14.4919769630 15464296 17225452 6897625
MESH:D010051 Ovarian Neoplasms Estradiol 14.4919401270
MESH:D010051 Ovarian Neoplasms Paclitaxel 14.4911161223
MESH:D010146 Pain Acetaminophen 2.2716870215
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 8.4015580305
MESH:D010190 Pancreatic Neoplasms Cisplatin 8.4019003803
MESH:D010190 Pancreatic Neoplasms Fluorouracil 8.4016929163 19003803 16500647 15113037
MESH:D010235 Paraganglioma arsenic trioxide 4.0219927285
MESH:D010382 Peliosis Hepatis Tetrachlorodibenzodioxin 4.1012520081
MESH:D010523 Peripheral Nervous System Diseases Arsenic 9.5716093927
MESH:D010523 Peripheral Nervous System Diseases Cisplatin 9.5715464296
MESH:D016491 Peripheral Vascular Diseases Arsenic 12.5816905509 6392382 15371236
MESH:D016491 Peripheral Vascular Diseases Cadmium 12.5815687053
MESH:D010997 Pleural Neoplasms Cisplatin 5.1917638057
MESH:D011141 Polyuria Furosemide 5.5017945291
MESH:D017119 Porphyria Cutanea Tarda Tetrachlorodibenzodioxin 3.4118163543
MESH:D011230 Precancerous Conditions Cyclosporine 3.0912371664
MESH:D011297 Prenatal Exposure Delayed Effects Tetrachlorodibenzodioxin 3.0411896295 11399792 11222880 11118676
MESH:D019048 Prostatic Intraepithelial Neoplasia Estradiol 3.7520887781
MESH:D011471 Prostatic Neoplasms Arsenic 1.8916140617
MESH:D011471 Prostatic Neoplasms arsenic trioxide 1.8919131511
MESH:D011471 Prostatic Neoplasms Cadmium 1.8917075824
MESH:D011471 Prostatic Neoplasms Estradiol 1.8916740699
MESH:D011471 Prostatic Neoplasms Fluorouracil 1.8918626508 19082440
MESH:D011471 Prostatic Neoplasms Paclitaxel 1.8916729912 17136230 17172428 16356831
MESH:D011507 Proteinuria Arsenic 3.8621343184
MESH:D011565 Psoriasis Cyclosporine 2.1816882103
MESH:D011618 Psychotic Disorders Cocaine 4.7116134406
MESH:D012004 Rectal Neoplasms Fluorouracil 3.8815538739 18286688 16160472 18722050
MESH:D051437 Renal Insufficiency Cisplatin 10.0815464296
MESH:D051437 Renal Insufficiency Folic Acid 10.0815728788
MESH:D015427 Reperfusion Injury Furosemide 3.8416526316
MESH:D012128 Respiratory Distress Syndrome, Adult Furosemide 4.4715912074 12394941 16096441
MESH:D015619 Respiratory System Abnormalities Tetrachlorodibenzodioxin 3.6918990726
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 9.8616646077
MESH:D012512 Sarcoma, Ewing's Cisplatin 9.8614601052
MESH:D012559 Schizophrenia Folic Acid 2.8816641680
MESH:D012640 Seizures Cocaine 3.9410454489
MESH:D012871 Skin Diseases Arsenic 5.2018709164 17548696 19834688 17050553 15952646 16702368 17453740 6392382 16353154 16759981 17938729
MESH:D012871 Skin Diseases Folic Acid 5.2018709164
MESH:D012878 Skin Neoplasms Arsenic 5.4717029826 15504454 17976673 19538983 17050553 16251483
MESH:D012878 Skin Neoplasms Tetrachlorodibenzodioxin 5.4716192470
MESH:D055752 Small Cell Lung Carcinoma Cisplatin 5.1915464296
MESH:D013118 Spinal Cord Diseases Folic Acid 5.3416361298
MESH:D013158 Splenic Diseases Dimethylnitrosamine 5.1212587719
MESH:D013274 Stomach Neoplasms arsenic trioxide 10.1817007042
MESH:D013274 Stomach Neoplasms Cisplatin 10.1817522103 18396642 15958060
MESH:D013274 Stomach Neoplasms Dimethylnitrosamine 10.1816033868
MESH:D013274 Stomach Neoplasms Fluorouracil 10.1817498489 17522103 17172411 18396642 19015929 18567086 15786421 19084572 16424979 16951190
MESH:D013274 Stomach Neoplasms Folic Acid 10.1817171786
MESH:D013274 Stomach Neoplasms Furosemide 10.1817052386
MESH:D013274 Stomach Neoplasms Paclitaxel 10.1818506536 18396642
MESH:D020521 Stroke Folic Acid 4.2116517955
MESH:D024801 Tauopathies Paclitaxel 4.6616930453
MESH:D013733 Testicular Diseases pyrazole 4.666499806
MESH:D013736 Testicular Neoplasms Cisplatin 4.4915464296 17225452
MESH:D013959 Thyroid Diseases Tetrachlorodibenzodioxin 3.7512697716
MESH:D013964 Thyroid Neoplasms arsenic trioxide 2.9719014326
MESH:D013978 Tibial Fractures Estradiol 4.5319048282
MESH:D014062 Tongue Neoplasms Fluorouracil 3.8516280240
MESH:D016171 Torsades de Pointes arsenic trioxide 3.8115213294
MESH:D001749 Urinary Bladder Neoplasms Arsenic 8.1211144890 18640142 19322015 15987713 17306315 19429237 17976673
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 8.1212845720 20435036 11780464 12973940
MESH:D001749 Urinary Bladder Neoplasms Cisplatin 8.1215464296 17225452 12973940
MESH:D014581 Urticaria Acetaminophen 2.8310982225
MESH:D002583 Uterine Cervical Neoplasms Cisplatin 9.2016803524
MESH:D002583 Uterine Cervical Neoplasms Fluorouracil 9.2016803524
MESH:D014605 Uveitis Cyclosporine 3.831336536
MESH:D014625 Vaginal Neoplasms Cisplatin 4.4615577323
MESH:D014652 Vascular Diseases Arsenic 4.5817056641
MESH:D054079 Vascular Malformations Tetrachlorodibenzodioxin 4.4412125929
MESH:D014839 Vomiting Cisplatin 4.5711897121
MESH:D019282 Wasting Syndrome Tetrachlorodibenzodioxin 4.1015886252
MESH:D014985 Xerophthalmia Cyclosporine 4.2917120751
No data
Pharmacogenomics Knowledge Base Top
  • PharmGKB Accession:PA26515
    • No data
    Releated disease ID Related disease Name
    PA446155Precursor Cell Lymphoblastic Leukemia-Lymphoma
    No data
    Drug Bank Top

    Simple Query:


      (e.g. CHD8)

    Syndromic Genes

    Non-syndromic Genes

    AutismKB Statistics

    • Studies: 1,036
    • Genes: 1,379
    • CNVs/SVs: 5,420
    • SNVs/Indels: 11,669
    • de novo Mutations: 5,669
    • Mosaics: 789
    • Linkage Regions: 172
    • Paper Collected: 6/30/2018
    • Last Update: 8/26/2018


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