AutismKB 2.0

Annotation Detail for FILIP1


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Basic Information Top
Gene Symbol:FILIP1 ( FILIP,KIAA1275 )
Gene Full Name: filamin A interacting protein 1
Band: 6q14.1
Quick LinksEntrez ID:27145; OMIM: 607307; Uniprot ID:FLIP1_HUMAN; ENSEMBL ID: ENSG00000118407; HGNC ID: 21015
Relate to Another Database: SFARIGene; denovo-db
Related Pathway Information Top
Related Diseases/Disorders Top
Comparative Toxicogenomics Database Top
Chemical ID Chemical Name Interaction Interaction Action Publication
C023514 2,6-dinitrotoluene 2,6-dinitrotoluene affects the expression of FILIP1 mRNAaffects expression 20406850
D000643 Ammonium Chloride Ammonium Chloride affects the expression of FILIP1 mRNAaffects expression 16483693
C006632 arsenic trioxide arsenic trioxide results in increased expression of FILIP1 mRNAincreases expression 20458559
C014347 decitabine decitabine results in increased expression of FILIP1 mRNAincreases expression 16367923
C023036 perfluorooctanoic acid perfluorooctanoic acid results in decreased expression of FILIP1 mRNAdecreases expression 16221955
Disease ID Disease Name Direct Evidence Inference Chemical Name Inference Score Publication
MESH:D000138 Acidosis Ammonium Chloride 4.1018287403
MESH:D000230 Adenocarcinoma arsenic trioxide 2.3511798837 19825857
MESH:D001778 Blood Coagulation Disorders arsenic trioxide 4.0416206674
MESH:D001943 Breast Neoplasms decitabine 2.5419208741 18320071
MESH:D002051 Burkitt Lymphoma arsenic trioxide 4.7311589617
MESH:D006528 Carcinoma, Hepatocellular 2,6-dinitrotoluene 3.1616705839
MESH:D006528 Carcinoma, Hepatocellular arsenic trioxide 3.1614691202 15553829 16217749 11135700 15073043
MESH:D002291 Carcinoma, Papillary arsenic trioxide 5.4919014326
MESH:D018288 Carcinoma, Small Cell arsenic trioxide 4.4712490120
MESH:D002294 Carcinoma, Squamous Cell decitabine 2.6719215824
MESH:D002471 Cell Transformation, Neoplastic 2,6-dinitrotoluene 3.006135515
MESH:D003110 Colonic Neoplasms decitabine 2.3817616700
MESH:D015179 Colorectal Neoplasms arsenic trioxide 2.6520501625
MESH:D015179 Colorectal Neoplasms decitabine 2.6518981723
MESH:D023903 Coronary Restenosis arsenic trioxide 4.6312609071
MESH:D019465 Craniofacial Abnormalities arsenic trioxide 1.8910525206
MESH:D003490 Cyanosis 2,6-dinitrotoluene 4.5018551238
MESH:D016757 Death, Sudden, Cardiac arsenic trioxide 4.5015213294
MESH:D056486 Drug-Induced Liver Injury 2,6-dinitrotoluene 2.0418551238 21346803
MESH:D004487 Edema perfluorooctanoic acid 3.9517259670 12083418
MESH:D004701 Endocrine Gland Neoplasms decitabine 5.7319294695
MESH:D004938 Esophageal Neoplasms arsenic trioxide 2.3812903497
MESH:D005234 Fatty Liver arsenic trioxide 3.6615073043
MESH:D005706 Gallbladder Neoplasms arsenic trioxide 4.7016904648
MESH:D006258 Head and Neck Neoplasms decitabine 3.7119215824
MESH:D006529 Hepatomegaly perfluorooctanoic acid 4.583609246
MESH:D006930 Hyperalgesia perfluorooctanoic acid 4.1412083418
MESH:D007248 Infertility, Male decitabine 3.4217581917
MESH:D007249 Inflammation perfluorooctanoic acid 3.2112083418
MESH:D007680 Kidney Neoplasms 2,6-dinitrotoluene 3.2816705839
MESH:D007938 Leukemia arsenic trioxide 6.9615070760
MESH:D007938 Leukemia decitabine 6.9618980019 19235587
MESH:D015459 Leukemia-Lymphoma, Adult T-Cell arsenic trioxide 4.1717077332 12560223
MESH:D007948 Leukemia, Monocytic, Acute arsenic trioxide 4.8516972261
MESH:D015464 Leukemia, Myelogenous, Chronic, BCR-ABL Positive arsenic trioxide 3.6914633726
MESH:D007951 Leukemia, Myeloid arsenic trioxide 10.8619077051
MESH:D007951 Leukemia, Myeloid decitabine 10.8618454857 19117987 17236224
MESH:D015470 Leukemia, Myeloid, Acute arsenic trioxide 4.1617050201 16467208 20471514 19850784 16968895
MESH:D015470 Leukemia, Myeloid, Acute decitabine 4.1617679729 18206229 19010910 19387464 18460780 18704418
MESH:D015477 Leukemia, Myelomonocytic, Chronic decitabine 6.0718055864
MESH:D015473 Leukemia, Promyelocytic, Acute arsenic trioxide 3.4319642359 17869043 16823087 16330433 17107899 15622746 17712046 19225113 15213294 11161223 16891316 16331271 12712474 16966277 17649720 15336539 19075265 12679006 11468182 15748426 19035177 17217047 16112521 9834237 12018890
MESH:D015458 Leukemia, T-Cell arsenic trioxide 4.7916882451
MESH:D007984 Leydig Cell Tumor perfluorooctanoic acid 5.778812269
MESH:D008113 Liver Neoplasms 2,6-dinitrotoluene 8.217678174
MESH:D008113 Liver Neoplasms arsenic trioxide 8.2114682389
MESH:D008113 Liver Neoplasms perfluorooctanoic acid 8.2114757943 18709148
MESH:D008114 Liver Neoplasms, Experimental 2,6-dinitrotoluene 6.652876784 6135515 2876786
MESH:D008114 Liver Neoplasms, Experimental arsenic trioxide 6.6520377131
MESH:D008133 Long QT Syndrome arsenic trioxide 3.6215213294
MESH:D008175 Lung Neoplasms arsenic trioxide 1.8719825857 11798837
MESH:D008223 Lymphoma decitabine 3.6619470736
MESH:D008545 Melanoma decitabine 2.2816505122 17785578
MESH:D009101 Multiple Myeloma arsenic trioxide 8.2111468182 19417148 14977855 19549372 15949261
MESH:D009101 Multiple Myeloma decitabine 8.2118172295
MESH:D009182 Mycosis Fungoides arsenic trioxide 5.2818349030
MESH:D009190 Myelodysplastic Syndromes arsenic trioxide 8.1016105982 16882451
MESH:D009190 Myelodysplastic Syndromes decitabine 8.1016882708 19157545 18608210 19010910
MESH:D009336 Necrosis 2,6-dinitrotoluene 4.4018551238 7678174
MESH:D009361 Neoplasm Invasiveness arsenic trioxide 4.4016624393
MESH:D009369 Neoplasms decitabine 2.8619470736 19116145 17925555
MESH:D009436 Neural Tube Defects arsenic trioxide 3.3310525206
MESH:D052556 Niemann-Pick Disease, Type C perfluorooctanoic acid 5.449802331
MESH:D009784 Occupational Diseases 2,6-dinitrotoluene 3.7816049721
MESH:D010051 Ovarian Neoplasms arsenic trioxide 5.2819769630 12452020 16624393
MESH:D010051 Ovarian Neoplasms decitabine 5.2819331143 19259094
MESH:D010190 Pancreatic Neoplasms arsenic trioxide 5.7515580305
MESH:D010190 Pancreatic Neoplasms decitabine 5.7519294695
MESH:D010235 Paraganglioma arsenic trioxide 4.5719927285
MESH:D011297 Prenatal Exposure Delayed Effects perfluorooctanoic acid 4.9317132714
MESH:D055728 Primary Myelofibrosis decitabine 5.2117616702
MESH:D011471 Prostatic Neoplasms arsenic trioxide 3.2219131511
MESH:D012208 Rhabdomyosarcoma decitabine 4.8119155313
MESH:D012512 Sarcoma, Ewing's arsenic trioxide 4.4016646077
MESH:D012640 Seizures 2,6-dinitrotoluene 2.7618551238
MESH:D013274 Stomach Neoplasms marker/mechanism 16367923
MESH:D013274 Stomach Neoplasms arsenic trioxide 2.6317007042
MESH:D013274 Stomach Neoplasms decitabine 2.6319037991
MESH:D013964 Thyroid Neoplasms arsenic trioxide 8.2419014326
MESH:D013964 Thyroid Neoplasms decitabine 8.2417967635
MESH:D016171 Torsades de Pointes arsenic trioxide 4.5015213294
MESH:D001749 Urinary Bladder Neoplasms 2,6-dinitrotoluene 9.0416049721
MESH:D001749 Urinary Bladder Neoplasms arsenic trioxide 9.0420435036 12973940 12845720 11780464
MESH:D001749 Urinary Bladder Neoplasms decitabine 9.0419087683 17616700
MESH:D014571 Urologic Neoplasms 2,6-dinitrotoluene 4.8610091137
MESH:D014604 Uveal Neoplasms decitabine 5.5217785578
No data
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AutismKB Statistics

  • Studies: 1,036
  • Genes: 1,379
  • CNVs/SVs: 5,420
  • SNVs/Indels: 11,669
  • de novo Mutations: 5,669
  • Mosaics: 789
  • Linkage Regions: 172
  • Paper Collected: 6/30/2018
  • Last Update: 8/26/2018


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